JP2004531270A5 - - Google Patents

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Publication number
JP2004531270A5
JP2004531270A5 JP2003507235A JP2003507235A JP2004531270A5 JP 2004531270 A5 JP2004531270 A5 JP 2004531270A5 JP 2003507235 A JP2003507235 A JP 2003507235A JP 2003507235 A JP2003507235 A JP 2003507235A JP 2004531270 A5 JP2004531270 A5 JP 2004531270A5
Authority
JP
Japan
Prior art keywords
monoclonal antibody
antibody
kda
antigen
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003507235A
Other languages
English (en)
Japanese (ja)
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JP2004531270A (ja
JP4455876B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/019646 external-priority patent/WO2003000848A2/en
Publication of JP2004531270A publication Critical patent/JP2004531270A/ja
Publication of JP2004531270A5 publication Critical patent/JP2004531270A5/ja
Application granted granted Critical
Publication of JP4455876B2 publication Critical patent/JP4455876B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2003507235A 2001-06-22 2002-06-21 肝移植細胞、アッセイ法、およびその使用法 Expired - Fee Related JP4455876B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30053501P 2001-06-22 2001-06-22
PCT/US2002/019646 WO2003000848A2 (en) 2001-06-22 2002-06-21 Liver engrafting cells, assays, and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009090608A Division JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Publications (3)

Publication Number Publication Date
JP2004531270A JP2004531270A (ja) 2004-10-14
JP2004531270A5 true JP2004531270A5 (https=) 2006-01-05
JP4455876B2 JP4455876B2 (ja) 2010-04-21

Family

ID=23159503

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003507235A Expired - Fee Related JP4455876B2 (ja) 2001-06-22 2002-06-21 肝移植細胞、アッセイ法、およびその使用法
JP2009090608A Withdrawn JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009090608A Withdrawn JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Country Status (11)

Country Link
US (3) US7211404B2 (https=)
EP (3) EP2388330B1 (https=)
JP (2) JP4455876B2 (https=)
CN (2) CN1665920A (https=)
AT (1) ATE371018T1 (https=)
AU (1) AU2002315392B2 (https=)
CA (1) CA2451637C (https=)
DE (1) DE60221987T2 (https=)
DK (1) DK1406998T3 (https=)
ES (1) ES2292772T3 (https=)
WO (1) WO2003000848A2 (https=)

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US20050014217A1 (en) * 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
AU2005209909B8 (en) * 2004-02-03 2009-01-15 The Regents Of The University Of Michigan Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
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EP1907858A4 (en) * 2005-06-13 2009-04-08 Univ Michigan COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
WO2006135886A2 (en) * 2005-06-13 2006-12-21 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
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WO2008121102A2 (en) * 2006-02-21 2008-10-09 The Regents Of The University Of Michigan Hedgehog signaling pathway antagonist cancer treatment
WO2008092002A2 (en) 2007-01-24 2008-07-31 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing pancreatic cancer
JP5497639B2 (ja) * 2007-06-05 2014-05-21 オレゴン ヘルス アンド サイエンス ユニバーシティ 生体内でヒト肝細胞を増大させる方法
JP2010534065A (ja) * 2007-07-20 2010-11-04 セルアーティス アーベー ヒト胚盤胞幹細胞に、胚体内胚葉（ＤＥ‐ｈｅｐ）を介して由来する新規な肝細胞の集団
WO2009075856A1 (en) * 2007-12-10 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Regenerative dot cells
WO2009111778A2 (en) * 2008-03-07 2009-09-11 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Lymph nodes as a site for regeneration
CN103002911B (zh) 2008-09-26 2015-08-26 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
US20100227393A1 (en) * 2009-03-06 2010-09-09 Eric Lagasse Liver stem cells: isolation of hepatic progenitor cells from the human gall bladder
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Ｗｎｔ拮抗劑及治療和篩選方法
JPWO2011102532A1 (ja) * 2010-02-16 2013-06-17 国立大学法人九州大学 誘導肝細胞
CA2794674A1 (en) 2010-04-01 2011-10-06 Oncomed Pharmaceuticals, Inc. Frizzled-binding agents and uses thereof
WO2014066328A1 (en) 2012-10-23 2014-05-01 Oncomed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using wnt pathway-binding agents
JP2016510411A (ja) 2013-02-04 2016-04-07 オンコメッド ファーマシューティカルズ インコーポレイテッド Ｗｎｔ経路インヒビターによる処置の方法およびモニタリング
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
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JP6672603B2 (ja) * 2015-03-27 2020-03-25 株式会社豊田中央研究所 物質と細胞との間の作用の評価方法
KR102664078B1 (ko) 2015-06-23 2024-05-10 더 잭슨 래보라토리 환자-유래 이종이식을 가지는 hla-비매칭의 인간화된 nsg 마우스 모델
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US20210238257A1 (en) * 2018-04-27 2021-08-05 The Regents Of The University Of California De Novo Formation of the Biliary System by Hepatocyte Transdifferentiation
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