JP2004531225A - ペプチド、蛋白質及び疑似ペプチド合成のための方法及び組成物 - Google Patents

ペプチド、蛋白質及び疑似ペプチド合成のための方法及び組成物 Download PDF

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JP2004531225A
JP2004531225A JP2002559580A JP2002559580A JP2004531225A JP 2004531225 A JP2004531225 A JP 2004531225A JP 2002559580 A JP2002559580 A JP 2002559580A JP 2002559580 A JP2002559580 A JP 2002559580A JP 2004531225 A JP2004531225 A JP 2004531225A
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peptide
trna
translation system
translation
product
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JP2004531225A5 (https=
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シー．フォースター アントニー
シー．ブラックロウ スティーブン
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
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  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002559580A 2001-01-25 2002-01-25 ペプチド、蛋白質及び疑似ペプチド合成のための方法及び組成物 Pending JP2004531225A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26414701P 2001-01-25 2001-01-25
PCT/US2002/002344 WO2002059293A2 (en) 2001-01-25 2002-01-25 Process and compositions for peptide, protein and peptidomimetic synthesis

Related Child Applications (1)

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JP2010152192A Division JP4972191B2 (ja) 2001-01-25 2010-07-02 ペプチド、蛋白質及びペプチドミメティック合成のための方法及び組成物

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JP2004531225A true JP2004531225A (ja) 2004-10-14
JP2004531225A5 JP2004531225A5 (https=) 2005-12-22

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JP2002559580A Pending JP2004531225A (ja) 2001-01-25 2002-01-25 ペプチド、蛋白質及び疑似ペプチド合成のための方法及び組成物
JP2010152192A Expired - Lifetime JP4972191B2 (ja) 2001-01-25 2010-07-02 ペプチド、蛋白質及びペプチドミメティック合成のための方法及び組成物

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JP2010152192A Expired - Lifetime JP4972191B2 (ja) 2001-01-25 2010-07-02 ペプチド、蛋白質及びペプチドミメティック合成のための方法及び組成物

Country Status (7)

Country Link
US (1) US6977150B2 (https=)
EP (1) EP1356036B1 (https=)
JP (2) JP2004531225A (https=)
AT (1) ATE394482T1 (https=)
CA (1) CA2435812C (https=)
DE (1) DE60226411D1 (https=)
WO (1) WO2002059293A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4061043B2 (ja) 2000-12-28 2008-03-12 株式会社ポストゲノム研究所 ｉｎｖｉｔｒｏ転写／翻訳系によるペプチド等の製造方法
AU2003225085A1 (en) * 2002-04-19 2003-11-03 California Institute Of Technology Unnatural amino acid containing display libraries
WO2004110964A2 (en) * 2003-06-16 2004-12-23 Nuevolution A/S Encoded molecules by translation (emt)
EP2327724A3 (en) 2004-02-02 2011-07-27 Ambrx, Inc. Modified human growth hormone polypeptides and their uses
WO2007139573A1 (en) * 2006-05-31 2007-12-06 The Trustees Of Columbia University In The City Of New York Ribosome and rna display of biologically active small molecules
WO2007140471A2 (en) * 2006-05-31 2007-12-06 The Trustees Of Columbia University In The City Of New York Ribosome and rna display of biologically active small molecules
WO2008005529A2 (en) 2006-07-07 2008-01-10 The Trustees Columbia University In The City Of New York Cell-mediated directed evolution
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
CN102348807B (zh) * 2009-01-12 2015-04-15 苏特罗生物制药公司 利用体外蛋白合成体系将非天然氨基酸引入蛋白的单装载体系
CA2843955A1 (en) 2011-08-01 2013-02-07 The General Hospital Corporation Protein and peptide libraries
JP6421122B2 (ja) 2012-10-12 2018-11-07 ストロ バイオファーマ， インコーポレイテッド 改善された発現のための、細菌抽出物中の選択タンパク質のタンパク質分解不活性化
WO2014189768A1 (en) * 2013-05-19 2014-11-27 The Board Of Trustees Of The Leland Devices and methods for display of encoded peptides, polypeptides, and proteins on dna
WO2015084867A1 (en) 2013-12-02 2015-06-11 Brandeis University Multivalent glycopeptides that tightly bind to target proteins
EP3237906B8 (en) 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
EP3274459A4 (en) * 2015-03-27 2018-08-22 The University of Queensland Platform for non-natural amino acid incorporation into proteins
US11174479B2 (en) 2018-08-13 2021-11-16 The Board Of Trustees Of The Leland Stanford Junior University Devices and methods for display of encoded peptides, PolyPeptides, and proteins on DNA
BR112022002365A2 (pt) 2019-08-09 2022-04-26 Nutcracker Therapeutics Inc Métodos e aparelhos para fabricar e para remover material de uma composição terapêutica

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8124694A (en) 1993-10-29 1995-05-22 Affymax Technologies N.V. In vitro peptide and antibody display libraries
US5643722A (en) * 1994-05-11 1997-07-01 Trustees Of Boston University Methods for the detection and isolation of proteins
JP4061043B2 (ja) * 2000-12-28 2008-03-12 株式会社ポストゲノム研究所 ｉｎｖｉｔｒｏ転写／翻訳系によるペプチド等の製造方法

Also Published As

Publication number Publication date
EP1356036A2 (en) 2003-10-29
WO2002059293A3 (en) 2003-05-30
CA2435812C (en) 2012-03-27
WO2002059293A2 (en) 2002-08-01
US6977150B2 (en) 2005-12-20
JP2010259440A (ja) 2010-11-18
ATE394482T1 (de) 2008-05-15
US20040091955A1 (en) 2004-05-13
DE60226411D1 (de) 2008-06-19
AU2002255488A2 (en) 2002-08-06
JP4972191B2 (ja) 2012-07-11
CA2435812A1 (en) 2002-08-01
EP1356036B1 (en) 2008-05-07

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