JP2004528809A5 - - Google Patents
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- Publication number
- JP2004528809A5 JP2004528809A5 JP2002532629A JP2002532629A JP2004528809A5 JP 2004528809 A5 JP2004528809 A5 JP 2004528809A5 JP 2002532629 A JP2002532629 A JP 2002532629A JP 2002532629 A JP2002532629 A JP 2002532629A JP 2004528809 A5 JP2004528809 A5 JP 2004528809A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- sequence seq
- consensus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 description 10
- 101001130247 Homo sapiens Reticulon-4 receptor-like 2 Proteins 0.000 description 4
- 101001130249 Mus musculus Reticulon-4 receptor-like 1 Proteins 0.000 description 4
- 102000053414 human RTN4RL2 Human genes 0.000 description 4
- 102000000343 Nogo Receptor 1 Human genes 0.000 description 2
- 108010041199 Nogo Receptor 1 Proteins 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 239000002299 complementary DNA Substances 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 108091035707 Consensus sequence Proteins 0.000 description 1
- 101001130250 Homo sapiens Reticulon-4 receptor-like 1 Proteins 0.000 description 1
- 102000010410 Nogo Proteins Human genes 0.000 description 1
- 108010077641 Nogo Proteins Proteins 0.000 description 1
- 101710095853 Reticulon-4 receptor-like 1 Proteins 0.000 description 1
- 102100031540 Reticulon-4 receptor-like 1 Human genes 0.000 description 1
- 125000000539 amino acid group Chemical group 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23836100P | 2000-10-06 | 2000-10-06 | |
| PCT/US2001/031488 WO2002029059A2 (en) | 2000-10-06 | 2001-10-06 | Nogo receptor homologs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009022063A Division JP2009100767A (ja) | 2000-10-06 | 2009-02-02 | Ｎｏｇｏレセプターホモログ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004528809A JP2004528809A (ja) | 2004-09-24 |
| JP2004528809A5 true JP2004528809A5 (https=) | 2005-03-03 |
| JP4465148B2 JP4465148B2 (ja) | 2010-05-19 |
Family
ID=22897532
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002532629A Expired - Fee Related JP4465148B2 (ja) | 2000-10-06 | 2001-10-06 | Ｎｏｇｏレセプターホモログ |
| JP2009022063A Withdrawn JP2009100767A (ja) | 2000-10-06 | 2009-02-02 | Ｎｏｇｏレセプターホモログ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009022063A Withdrawn JP2009100767A (ja) | 2000-10-06 | 2009-02-02 | Ｎｏｇｏレセプターホモログ |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US20030124704A1 (https=) |
| EP (1) | EP1325130B1 (https=) |
| JP (2) | JP4465148B2 (https=) |
| AT (1) | ATE458815T1 (https=) |
| AU (2) | AU2002211539B2 (https=) |
| CA (1) | CA2424834A1 (https=) |
| DE (1) | DE60141409D1 (https=) |
| DK (1) | DK1325130T3 (https=) |
| ES (1) | ES2341608T3 (https=) |
| NZ (1) | NZ525422A (https=) |
| PT (1) | PT1325130E (https=) |
| WO (1) | WO2002029059A2 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7119165B2 (en) * | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| NZ525422A (en) * | 2000-10-06 | 2006-09-29 | Biogen Idec Inc | Isolated polynucleotides comprising a nucleic acid which encodes a polypeptide which modulates axonal growth in CNS neurons |
| JP2005507246A (ja) * | 2001-08-27 | 2005-03-17 | ノバルティス アクチエンゲゼルシャフト | Ｎｏｇｏレセプターホモログおよびそれらの使用 |
| WO2003035687A1 (en) * | 2001-10-22 | 2003-05-01 | Novartis Ag | Nogo receptor homologues and their use |
| US7309485B2 (en) * | 2001-12-03 | 2007-12-18 | Children's Medical Center Corporation | Reducing myelin-mediated inhibition of axon regeneration |
| JPWO2004005510A1 (ja) * | 2002-07-05 | 2005-11-04 | 塩野義製薬株式会社 | 新規Ｎｏｇｏ受容体様ポリペプチドおよびそのＤＮＡ |
| PT1534736E (pt) | 2002-08-10 | 2010-09-07 | Univ Yale | Antagonistas do receptor nogo |
| WO2004085648A2 (en) * | 2003-03-19 | 2004-10-07 | Biogen Idec Ma Inc. | Nogo receptor binding protein |
| US7541335B2 (en) | 2003-04-04 | 2009-06-02 | University Of Rochester | Nogo-receptors and methods of use |
| EP1615654A2 (en) * | 2003-04-16 | 2006-01-18 | Yale University | Nogo-receptor antagonists for the treatment of conditions involving amyloid plaques |
| US20080274112A1 (en) * | 2003-08-07 | 2008-11-06 | Lee Daniel H S | Nogo Receptor Antagonists |
| WO2005059515A2 (en) * | 2003-12-16 | 2005-06-30 | Children's Medical Center Corporation | Method for treating neurological disorders |
| US8912144B2 (en) * | 2003-12-16 | 2014-12-16 | Children's Medical Center Corporation | Method for treating stroke via administration of NEP1-40 and inosine |
| CA2555018A1 (en) * | 2004-01-30 | 2005-08-18 | Biogen Idec Ma Inc. | Treatment of conditions involving dopaminergic neuronal degeneration using nogo receptor antagonists |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| WO2006047049A2 (en) * | 2004-10-01 | 2006-05-04 | Yale University | Nogo-a polypeptide fragments, variant nogo receptor-1 polypeptides, and uses thereof |
| US7893032B2 (en) * | 2005-07-07 | 2011-02-22 | Yale University | NgR variants and compositions thereof for suppressing axonal growth inhibition |
| SI1904104T1 (sl) | 2005-07-08 | 2013-12-31 | Biogen Idec Ma Inc. | Protitelesa SP35 in njihova uporaba |
| CN101248083A (zh) * | 2005-08-25 | 2008-08-20 | 比奥根艾迪克Ma公司 | Nogo受体多肽和多肽片段及其用途 |
| CA2913655A1 (en) | 2006-01-27 | 2007-08-09 | Biogen Ma Inc. | Nogo receptor antagonists |
| JP2009538282A (ja) * | 2006-05-15 | 2009-11-05 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 乏突起膠細胞の生存を促進させるためのＮｏｇｏ受容体−１（ＮｇＲ１）アンタゴニストの使用 |
| WO2007137303A2 (en) * | 2006-05-24 | 2007-11-29 | Myelin Repair Foundation, Inc. | Permeability of blood-brain barrier |
| US20100047232A1 (en) * | 2006-11-14 | 2010-02-25 | Jasvinder Atwal | Modulators of neuronal regeneration |
| ES2437110T3 (es) * | 2006-11-14 | 2014-01-08 | Genentech, Inc. | Moduladores de la regeneración neuronal |
| WO2009009743A2 (en) * | 2007-07-12 | 2009-01-15 | Institute For Advance Study | Sequence optimization for expression of a foreign gene |
| KR20100109923A (ko) * | 2007-12-11 | 2010-10-11 | 제넨테크, 인크. | 뉴런 재생의 조정인자 |
| EP2276500A4 (en) | 2008-03-13 | 2015-03-04 | Univ Yale | REACTIVATION OF AXON GROWTH AND AXON RECOVERY IN CHRONIC REVERSE MARKET INJURIES |
| CL2009001155A1 (es) * | 2008-05-13 | 2010-06-04 | Genentech Inc | Anticuerpo anti-pirb/lilrb aislado; polinucleotido que lo codifica; vector; celula huesped; metodo de obtencion; composicion farmaceutica que lo comprende; kit; y su uso para tratar enfermedades neurodegenerativas. |
| DK2982695T3 (da) | 2008-07-09 | 2019-05-13 | Biogen Ma Inc | Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf |
| EP2392208B1 (en) * | 2010-06-07 | 2016-05-04 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a non-specific cleavage domain of a restriction nuclease and their use |
| US9120111B2 (en) | 2012-02-24 | 2015-09-01 | Rain Bird Corporation | Arc adjustable rotary sprinkler having full-circle operation and automatic matched precipitation |
| CN104470541A (zh) | 2012-05-14 | 2015-03-25 | 比奥根艾迪克Ma公司 | 用于治疗涉及运动神经元的疾患的lingo-2拮抗剂 |
| US9156043B2 (en) | 2012-07-13 | 2015-10-13 | Rain Bird Corporation | Arc adjustable rotary sprinkler with automatic matched precipitation |
| JP2018504400A (ja) | 2015-01-08 | 2018-02-15 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用 |
| US12343748B2 (en) | 2021-03-16 | 2025-07-01 | Rain Bird Corporation | Multi-mode rotor sprinkler apparatus and method |
| US12434252B2 (en) | 2022-04-20 | 2025-10-07 | Rain Bird Corporation | Full-circle and part-circle rotor sprinkler |
| US12440855B2 (en) | 2022-10-27 | 2025-10-14 | Rain Bird Corporation | Multi-mode rotor sprinkler apparatus and method |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341050C (en) | 1988-11-04 | 2000-07-11 | Martin E. Schwab | Neurite growth regulatory factors |
| DE68923362T2 (de) | 1988-11-04 | 1996-03-28 | Zuerich Erziehungsdirektion | Wachstumsregelfaktoren für neuriten. |
| US5250414A (en) | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
| WO1994017831A1 (en) | 1993-02-11 | 1994-08-18 | Erziehungsdirektion Of The Canton Zurich | A combination of neurotrophin and antibody directed toward myelin-associated neurite growth inhibitory protein promotes central nervous system regeneration |
| WO2000073452A2 (en) | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US5858708A (en) | 1996-08-12 | 1999-01-12 | Bandman; Olga | Polynucleotides encoding two novel human neuroendocrine-specific proteins |
| WO2000053756A2 (en) | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO1999066041A1 (en) | 1998-06-16 | 1999-12-23 | Human Genome Sciences, Inc. | 94 human secreted proteins |
| WO2000070050A1 (en) | 1999-05-14 | 2000-11-23 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| JP2003521216A (ja) * | 1997-08-05 | 2003-07-15 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ９０個のヒト分泌タンパク質 |
| JP3868740B2 (ja) | 1998-03-10 | 2007-01-17 | ジェネンテック・インコーポレーテッド | 新規なポリペプチド及びそれをコードする核酸 |
| DE69942803D1 (de) | 1998-07-22 | 2010-11-11 | Smithkline Beecham Ltd | Rotein änhelt, und dafür kodierende cdns |
| CZ304224B6 (cs) * | 1998-11-06 | 2014-01-15 | Schwab | Monoklonální protilátka |
| KR100529270B1 (ko) | 1998-12-01 | 2005-11-21 | 제넨테크, 인크. | 혈관신생 및 심혈관형성의 촉진 또는 억제 |
| JP3993746B2 (ja) | 1998-12-22 | 2007-10-17 | ジェネンテック・インコーポレーテッド | 腫瘍性細胞成長阻害のための組成物及び方法 |
| CA2362427A1 (en) | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| CA2383592A1 (en) | 1999-03-31 | 2000-10-05 | Curagen Corporation | 2384891 acids including open reading frames encoding polypeptides; orfx |
| WO2001009162A2 (en) | 1999-07-30 | 2001-02-08 | Millennium Pharmaceuticals, Inc. | Secreted proteins and uses thereof |
| WO2001042286A2 (en) | 1999-12-08 | 2001-06-14 | Millennium Pharmaceuticals, Inc. | Human leucine rich repeat-containing polypeptide and uses therefor |
| IL150566A0 (en) * | 2000-01-12 | 2003-02-12 | Univ Yale | Nucleic acids and polypeptides and nogo-receptor proteins |
| US7119165B2 (en) | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| CA2376873A1 (en) | 2000-04-18 | 2001-10-25 | Teijin Limited | Oxygen concentrating apparatus |
| NZ525422A (en) | 2000-10-06 | 2006-09-29 | Biogen Idec Inc | Isolated polynucleotides comprising a nucleic acid which encodes a polypeptide which modulates axonal growth in CNS neurons |
| JP2005507246A (ja) | 2001-08-27 | 2005-03-17 | ノバルティス アクチエンゲゼルシャフト | Ｎｏｇｏレセプターホモログおよびそれらの使用 |
| WO2003035687A1 (en) | 2001-10-22 | 2003-05-01 | Novartis Ag | Nogo receptor homologues and their use |
| PT1534736E (pt) | 2002-08-10 | 2010-09-07 | Univ Yale | Antagonistas do receptor nogo |
-
2001
- 2001-10-06 NZ NZ525422A patent/NZ525422A/en unknown
- 2001-10-06 AT AT01979595T patent/ATE458815T1/de active
- 2001-10-06 WO PCT/US2001/031488 patent/WO2002029059A2/en not_active Ceased
- 2001-10-06 JP JP2002532629A patent/JP4465148B2/ja not_active Expired - Fee Related
- 2001-10-06 AU AU2002211539A patent/AU2002211539B2/en not_active Ceased
- 2001-10-06 PT PT01979595T patent/PT1325130E/pt unknown
- 2001-10-06 DE DE60141409T patent/DE60141409D1/de not_active Expired - Lifetime
- 2001-10-06 ES ES01979595T patent/ES2341608T3/es not_active Expired - Lifetime
- 2001-10-06 CA CA002424834A patent/CA2424834A1/en not_active Abandoned
- 2001-10-06 DK DK01979595.4T patent/DK1325130T3/da active
- 2001-10-06 AU AU1153902A patent/AU1153902A/xx active Pending
- 2001-10-06 US US09/972,546 patent/US20030124704A1/en not_active Abandoned
- 2001-10-06 EP EP01979595A patent/EP1325130B1/en not_active Expired - Lifetime
-
2003
- 2003-12-12 US US10/735,256 patent/US7173118B2/en not_active Expired - Lifetime
-
2006
- 2006-10-06 US US11/544,013 patent/US7456255B2/en not_active Expired - Lifetime
-
2008
- 2008-11-24 US US12/277,187 patent/US20090175850A1/en not_active Abandoned
-
2009
- 2009-02-02 JP JP2009022063A patent/JP2009100767A/ja not_active Withdrawn
-
2010
- 2010-11-23 US US12/952,747 patent/US20110129477A1/en not_active Abandoned
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