JP2004528321A - ステロールおよびサポニンを含むポリヌクレオチド結合複合体 - Google Patents

ステロールおよびサポニンを含むポリヌクレオチド結合複合体 Download PDF

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JP2004528321A
JP2004528321A JP2002579019A JP2002579019A JP2004528321A JP 2004528321 A JP2004528321 A JP 2004528321A JP 2002579019 A JP2002579019 A JP 2002579019A JP 2002579019 A JP2002579019 A JP 2002579019A JP 2004528321 A JP2004528321 A JP 2004528321A
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conjugate
saponin
sterol
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group
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JP2004528321A5 (enExample
Inventor
セーレン キルビュ,ニコライ
ダルスガールト,クリスティアン
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ノルディック ワクチン テクノロジー アクティーゼルスカブ
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Publication of JP2004528321A publication Critical patent/JP2004528321A/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
JP2002579019A 2001-04-04 2002-04-04 ステロールおよびサポニンを含むポリヌクレオチド結合複合体 Withdrawn JP2004528321A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200100560 2001-04-04
US30860901P 2001-07-31 2001-07-31
PCT/DK2002/000229 WO2002080981A2 (en) 2001-04-04 2002-04-04 Polynucleotide binding complexes comprising sterols and saponins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010120290A Division JP2010180249A (ja) 2001-04-04 2010-05-26 ステロールおよびサポニンを含むポリヌクレオチド結合複合体

Publications (2)

Publication Number Publication Date
JP2004528321A true JP2004528321A (ja) 2004-09-16
JP2004528321A5 JP2004528321A5 (enExample) 2005-12-22

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Family Applications (2)

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JP2002579019A Withdrawn JP2004528321A (ja) 2001-04-04 2002-04-04 ステロールおよびサポニンを含むポリヌクレオチド結合複合体
JP2010120290A Pending JP2010180249A (ja) 2001-04-04 2010-05-26 ステロールおよびサポニンを含むポリヌクレオチド結合複合体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010120290A Pending JP2010180249A (ja) 2001-04-04 2010-05-26 ステロールおよびサポニンを含むポリヌクレオチド結合複合体

Country Status (7)

Country Link
EP (2) EP2011517A1 (enExample)
JP (2) JP2004528321A (enExample)
AT (1) ATE409495T1 (enExample)
DE (1) DE60229118D1 (enExample)
DK (1) DK1377320T3 (enExample)
NZ (1) NZ529347A (enExample)
WO (1) WO2002080981A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020526536A (ja) * 2017-07-11 2020-08-31 フライエ ウニヴェルジテート ベルリン サポニンの新規な使用およびその分離のための方法

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EP1545605B8 (en) * 2002-10-02 2010-05-26 Nordic Vaccine A/S Composition for vaccination
WO2009106085A1 (en) * 2008-02-28 2009-09-03 Nordic Vaccine A/S Vaccine compositions comprising saccharide antigens
PT2750683T (pt) 2011-10-03 2018-06-26 Mx Adjuvac Ab Nanopartículas, processo de preparação e seu uso como transportadores para moléculas hidrofóbicas anfipáticas no domínio da medicina, incluindo tratamento de cancro e compostos relacionados a alimentos
AR095962A1 (es) 2013-04-01 2015-11-25 Moreinx Ab Nanopartículas, compuestas de esterol y saponina de quillaja saponaria molina, proceso para preparación y uso de las mismas como portadores para moléculas anfipáticas o hidrófobas en el campo de la medicina incluyendo tratamiento de cáncer y compuestos relacionados con alimentos
CN108498376B (zh) * 2018-04-02 2020-11-13 榛硕(武汉)智能科技有限公司 一种甲基硅油乳液及其制备方法
CN109295080B (zh) * 2018-09-19 2021-08-20 昆明理工大学 珠子参β-香树脂醇合成酶基因Pjβ-AS的用途

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020526536A (ja) * 2017-07-11 2020-08-31 フライエ ウニヴェルジテート ベルリン サポニンの新規な使用およびその分離のための方法
US11708388B2 (en) 2017-07-11 2023-07-25 Freie Universität Berlin Uses of a saponin and method for its isolation
JP2023115283A (ja) * 2017-07-11 2023-08-18 フライエ ウニヴェルジテート ベルリン サポニンの新規な使用およびその分離のための方法

Also Published As

Publication number Publication date
NZ529347A (en) 2008-01-31
EP1377320B1 (en) 2008-10-01
ATE409495T1 (de) 2008-10-15
WO2002080981A2 (en) 2002-10-17
WO2002080981A3 (en) 2002-12-19
JP2010180249A (ja) 2010-08-19
EP1377320A2 (en) 2004-01-07
DK1377320T3 (da) 2009-02-09
DE60229118D1 (de) 2008-11-13
EP2011517A1 (en) 2009-01-07

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