JP2004526760A5 - - Google Patents
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- Publication number
- JP2004526760A5 JP2004526760A5 JP2002580921A JP2002580921A JP2004526760A5 JP 2004526760 A5 JP2004526760 A5 JP 2004526760A5 JP 2002580921 A JP2002580921 A JP 2002580921A JP 2002580921 A JP2002580921 A JP 2002580921A JP 2004526760 A5 JP2004526760 A5 JP 2004526760A5
- Authority
- JP
- Japan
- Prior art keywords
- toluene sulfonamide
- pharmaceutical composition
- para
- composition according
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- YCMLQMDWSXFTIF-UHFFFAOYSA-N 2-methylbenzenesulfonimidic acid Chemical compound CC1=CC=CC=C1S(N)(=O)=O YCMLQMDWSXFTIF-UHFFFAOYSA-N 0.000 claims 27
- 239000008194 pharmaceutical composition Substances 0.000 claims 24
- 239000003814 drug Substances 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 14
- LMYRWZFENFIFIT-UHFFFAOYSA-N toluene-4-sulfonamide Chemical compound CC1=CC=C(S(N)(=O)=O)C=C1 LMYRWZFENFIFIT-UHFFFAOYSA-N 0.000 claims 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 7
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 5
- RWLALWYNXFYRGW-UHFFFAOYSA-N 2-Ethyl-1,3-hexanediol Chemical compound CCCC(O)C(CC)CO RWLALWYNXFYRGW-UHFFFAOYSA-N 0.000 claims 4
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical compound OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims 3
- 229920000305 Nylon 6,10 Polymers 0.000 claims 2
- 230000000259 anti-tumor effect Effects 0.000 claims 2
- 210000004204 blood vessel Anatomy 0.000 claims 2
- 230000001747 exhibiting effect Effects 0.000 claims 2
- 235000012907 honey Nutrition 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 230000005748 tumor development Effects 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/835,908 US6727287B2 (en) | 2001-04-16 | 2001-04-16 | Toluene sulfonamide-containing anti-tumor composition and method of use thereof |
| PCT/US2002/011786 WO2002083117A1 (en) | 2001-04-16 | 2002-04-16 | Toluene sulfonamide-containing anti-tumor composition and method of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004526760A JP2004526760A (ja) | 2004-09-02 |
| JP2004526760A5 true JP2004526760A5 (enExample) | 2005-12-15 |
Family
ID=25270767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580921A Withdrawn JP2004526760A (ja) | 2001-04-16 | 2002-04-16 | トルエンスルフォンアミド含有抗腫瘍組成物及びその製造方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6727287B2 (enExample) |
| EP (1) | EP1389101B1 (enExample) |
| JP (1) | JP2004526760A (enExample) |
| CN (1) | CN100471491C (enExample) |
| AT (1) | ATE415960T1 (enExample) |
| AU (1) | AU2002303350B2 (enExample) |
| BR (1) | BR0208961A (enExample) |
| CA (1) | CA2444842A1 (enExample) |
| DE (1) | DE60230133D1 (enExample) |
| EA (1) | EA007685B1 (enExample) |
| ES (1) | ES2316565T3 (enExample) |
| IL (2) | IL158433A0 (enExample) |
| MX (1) | MXPA03009483A (enExample) |
| NZ (1) | NZ529513A (enExample) |
| WO (1) | WO2002083117A1 (enExample) |
| ZA (1) | ZA200308814B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005005397B4 (de) * | 2005-02-05 | 2008-08-21 | Lts Lohmann Therapie-Systeme Ag | Isolierung von N-Butylbenzolsulfonamid, Synthese von Benzolsulfonamid-Derivaten sowie Verwendung von N-Butylbenzolsulfonamid und Benzolsulfonamid-Derivaten zur Behandlung der benignen Prostatahyperplasie und/oder des Prostatakarzinoms |
| US7790928B1 (en) * | 2005-04-25 | 2010-09-07 | Albert Raymond Hechinger | Therapeutic dimethyl sulfoxide (aka DMSO) compositions and methods of use |
| EP1976495A2 (en) * | 2006-01-06 | 2008-10-08 | Aarhus Universitet | Compounds acting on the serotonin transporter |
| CN104473914B (zh) * | 2015-01-06 | 2017-01-11 | 天津红日药业股份有限公司 | 一种磺酰胺类药物组合物 |
| US10465742B2 (en) | 2015-10-29 | 2019-11-05 | Inteva Products, Llc | Cable end fitting and cable abutment and method of securement |
| US9782370B2 (en) * | 2015-12-21 | 2017-10-10 | Gongwin Biopharm Holdings Co., Ltd. | Pharmaceutical compositions of benzenesulfonamide derivatives for treatment of adenoid cystic carcinoma |
| US10182998B2 (en) * | 2016-06-10 | 2019-01-22 | Gongwin Biopharm Holdings Co., Ltd. | Benzenesulfonamide compositions for treatment of malignant pleural effusions |
| US9668990B1 (en) * | 2016-06-10 | 2017-06-06 | Gongwin Biopharm Holdings Co., Ltd. | Benzenesulfonamides compositions for treatment of malignant pleural effusions |
| US20180055796A1 (en) | 2016-08-23 | 2018-03-01 | Gongwin Biopharm Holdings Co., Ltd. | Pharmaceutical composition exhibiting anti-tumor activity, method for treating patient suffering from cancer and method for inhibiting tumor growth |
| KR20250020713A (ko) * | 2017-12-29 | 2025-02-11 | 공윈 바이오팜 컴퍼니, 리미티드 | 벤젠술폰아미드 유도체 및 지질 래프트 조정 방법 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3340148A (en) | 1961-03-22 | 1967-09-05 | Gillette Inhibitor Co | Treatment of fungus diseases of the skin |
| US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4777049A (en) | 1983-12-01 | 1988-10-11 | Alza Corporation | Constant release system with pulsed release |
| US4663308A (en) | 1984-07-18 | 1987-05-05 | Medical College Of Ohio | Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract |
| US4764381A (en) | 1985-12-06 | 1988-08-16 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol |
| US4983396A (en) | 1985-12-06 | 1991-01-08 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1,3-hexanediol |
| US5891454A (en) | 1997-03-28 | 1999-04-06 | Alexander Wu | Anti-cancer drug and special tumor necrotizing agent |
| CN1073415C (zh) | 1997-07-03 | 2001-10-24 | 吴宜庄 | 磺酰胺类化合物在制备抗癌药物中的应用 |
-
2001
- 2001-04-16 US US09/835,908 patent/US6727287B2/en not_active Expired - Lifetime
-
2002
- 2002-04-16 MX MXPA03009483A patent/MXPA03009483A/es active IP Right Grant
- 2002-04-16 BR BR0208961-0A patent/BR0208961A/pt not_active Application Discontinuation
- 2002-04-16 AU AU2002303350A patent/AU2002303350B2/en not_active Ceased
- 2002-04-16 AT AT02731370T patent/ATE415960T1/de not_active IP Right Cessation
- 2002-04-16 JP JP2002580921A patent/JP2004526760A/ja not_active Withdrawn
- 2002-04-16 EA EA200301126A patent/EA007685B1/ru not_active IP Right Cessation
- 2002-04-16 ES ES02731370T patent/ES2316565T3/es not_active Expired - Lifetime
- 2002-04-16 IL IL15843302A patent/IL158433A0/xx unknown
- 2002-04-16 EP EP02731370A patent/EP1389101B1/en not_active Expired - Lifetime
- 2002-04-16 DE DE60230133T patent/DE60230133D1/de not_active Expired - Lifetime
- 2002-04-16 CN CNB028106393A patent/CN100471491C/zh not_active Expired - Fee Related
- 2002-04-16 WO PCT/US2002/011786 patent/WO2002083117A1/en not_active Ceased
- 2002-04-16 CA CA002444842A patent/CA2444842A1/en not_active Abandoned
- 2002-04-16 NZ NZ529513A patent/NZ529513A/en not_active IP Right Cessation
-
2003
- 2003-10-15 IL IL158433A patent/IL158433A/en not_active IP Right Cessation
- 2003-11-12 ZA ZA200308814A patent/ZA200308814B/en unknown
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