BR0208961A - Composição farmacêutica demonstrando atividade anti-tumor, método para fabricar a mesma, e uso de uma tolueno sulfonamida - Google Patents

Composição farmacêutica demonstrando atividade anti-tumor, método para fabricar a mesma, e uso de uma tolueno sulfonamida

Info

Publication number
BR0208961A
BR0208961A BR0208961-0A BR0208961A BR0208961A BR 0208961 A BR0208961 A BR 0208961A BR 0208961 A BR0208961 A BR 0208961A BR 0208961 A BR0208961 A BR 0208961A
Authority
BR
Brazil
Prior art keywords
tumor activity
manufacturing
pharmaceutical composition
toluene sulfonamide
demonstrating anti
Prior art date
Application number
BR0208961-0A
Other languages
English (en)
Inventor
John Wu
Rocky C S Shih
Lester Wu
Original Assignee
Pts International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pts International Inc filed Critical Pts International Inc
Publication of BR0208961A publication Critical patent/BR0208961A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA DEMONSTRANDO ATIVIDADE ANTI-TUMOR, MéTODO PARA FABRICAR A MESMA, E USO DE UMA TOLUENO SULFONAMIDA". A invenção refere-se a uma composição que demonstra atividade anti-tumor e que compreende uma tolueno sulfonamida em uma concentração não previamente reconhecida como sendo eficaz para este fim. A composição demonstra a capacidade de inibir o crescimento de tumor, encolher (isto é, necrotizar) tumores e evitar a formação de tumores em humanos. A invenção também inclui métodos para fabricar e usar as composições.
BR0208961-0A 2001-04-16 2002-04-16 Composição farmacêutica demonstrando atividade anti-tumor, método para fabricar a mesma, e uso de uma tolueno sulfonamida BR0208961A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/835,908 US6727287B2 (en) 2001-04-16 2001-04-16 Toluene sulfonamide-containing anti-tumor composition and method of use thereof
PCT/US2002/011786 WO2002083117A1 (en) 2001-04-16 2002-04-16 Toluene sulfonamide-containing anti-tumor composition and method of use thereof

Publications (1)

Publication Number Publication Date
BR0208961A true BR0208961A (pt) 2005-02-01

Family

ID=25270767

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208961-0A BR0208961A (pt) 2001-04-16 2002-04-16 Composição farmacêutica demonstrando atividade anti-tumor, método para fabricar a mesma, e uso de uma tolueno sulfonamida

Country Status (17)

Country Link
US (1) US6727287B2 (pt)
EP (1) EP1389101B1 (pt)
JP (1) JP2004526760A (pt)
CN (1) CN100471491C (pt)
AT (1) ATE415960T1 (pt)
AU (1) AU2002303350B2 (pt)
BR (1) BR0208961A (pt)
CA (1) CA2444842A1 (pt)
DE (1) DE60230133D1 (pt)
EA (1) EA007685B1 (pt)
ES (1) ES2316565T3 (pt)
HK (1) HK1067545A1 (pt)
IL (2) IL158433A0 (pt)
MX (1) MXPA03009483A (pt)
NZ (1) NZ529513A (pt)
WO (1) WO2002083117A1 (pt)
ZA (1) ZA200308814B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005005397B4 (de) * 2005-02-05 2008-08-21 Lts Lohmann Therapie-Systeme Ag Isolierung von N-Butylbenzolsulfonamid, Synthese von Benzolsulfonamid-Derivaten sowie Verwendung von N-Butylbenzolsulfonamid und Benzolsulfonamid-Derivaten zur Behandlung der benignen Prostatahyperplasie und/oder des Prostatakarzinoms
US7790928B1 (en) * 2005-04-25 2010-09-07 Albert Raymond Hechinger Therapeutic dimethyl sulfoxide (aka DMSO) compositions and methods of use
EP1976495A2 (en) * 2006-01-06 2008-10-08 Aarhus Universitet Compounds acting on the serotonin transporter
CN104473914B (zh) * 2015-01-06 2017-01-11 天津红日药业股份有限公司 一种磺酰胺类药物组合物
CN106655030B (zh) 2015-10-29 2021-03-16 因特瓦产品有限责任公司 缆线端头配件和缆线接合器及其固定方法
US9782370B2 (en) 2015-12-21 2017-10-10 Gongwin Biopharm Holdings Co., Ltd. Pharmaceutical compositions of benzenesulfonamide derivatives for treatment of adenoid cystic carcinoma
US10182998B2 (en) * 2016-06-10 2019-01-22 Gongwin Biopharm Holdings Co., Ltd. Benzenesulfonamide compositions for treatment of malignant pleural effusions
US9668990B1 (en) 2016-06-10 2017-06-06 Gongwin Biopharm Holdings Co., Ltd. Benzenesulfonamides compositions for treatment of malignant pleural effusions
US20180055796A1 (en) * 2016-08-23 2018-03-01 Gongwin Biopharm Holdings Co., Ltd. Pharmaceutical composition exhibiting anti-tumor activity, method for treating patient suffering from cancer and method for inhibiting tumor growth
WO2019133797A1 (en) * 2017-12-29 2019-07-04 Wu, Lester J. Benzenesulfonamide derivatives and method for modulating lipid raft

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340148A (en) 1961-03-22 1967-09-05 Gillette Inhibitor Co Treatment of fungus diseases of the skin
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4160452A (en) 1977-04-07 1979-07-10 Alza Corporation Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4777049A (en) 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
US4663308A (en) 1984-07-18 1987-05-05 Medical College Of Ohio Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract
US4764381A (en) 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
US4983396A (en) 1985-12-06 1991-01-08 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1,3-hexanediol
US5891454A (en) 1997-03-28 1999-04-06 Alexander Wu Anti-cancer drug and special tumor necrotizing agent
CN1073415C (zh) 1997-07-03 2001-10-24 吴宜庄 磺酰胺类化合物在制备抗癌药物中的应用

Also Published As

Publication number Publication date
EP1389101B1 (en) 2008-12-03
HK1067545A1 (en) 2005-04-15
MXPA03009483A (es) 2004-12-06
ATE415960T1 (de) 2008-12-15
WO2002083117A1 (en) 2002-10-24
US6727287B2 (en) 2004-04-27
CN100471491C (zh) 2009-03-25
EP1389101A1 (en) 2004-02-18
US20030022843A1 (en) 2003-01-30
ZA200308814B (en) 2004-11-23
EA007685B1 (ru) 2006-12-29
EA200301126A1 (ru) 2004-06-24
EP1389101A4 (en) 2005-05-04
AU2002303350B2 (en) 2007-08-02
DE60230133D1 (de) 2009-01-15
JP2004526760A (ja) 2004-09-02
CN1511032A (zh) 2004-07-07
NZ529513A (en) 2005-10-28
IL158433A (en) 2010-11-30
ES2316565T3 (es) 2009-04-16
IL158433A0 (en) 2004-05-12
CA2444842A1 (en) 2002-10-24

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: PTS INTERNATIONAL, INC. (US), ROCKY C.H. SHIH (US), LESTER WU (US)

B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 31/18

Ipc: A61K 31/18 (2011.01), A61P 35/00 (2011.01)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.