JP2004525087A5 - - Google Patents
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- Publication number
- JP2004525087A5 JP2004525087A5 JP2002545472A JP2002545472A JP2004525087A5 JP 2004525087 A5 JP2004525087 A5 JP 2004525087A5 JP 2002545472 A JP2002545472 A JP 2002545472A JP 2002545472 A JP2002545472 A JP 2002545472A JP 2004525087 A5 JP2004525087 A5 JP 2004525087A5
- Authority
- JP
- Japan
- Prior art keywords
- aqueous solution
- group
- microbicide
- compound
- alexidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007864 aqueous solution Substances 0.000 claims 16
- 150000003839 salts Chemical class 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 4
- 230000003641 microbiacidal effect Effects 0.000 claims 4
- 229940124561 microbicide Drugs 0.000 claims 4
- 239000002855 microbicide agent Substances 0.000 claims 4
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims 3
- 229920002413 Polyhexanide Polymers 0.000 claims 3
- LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical compound CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 claims 3
- 229950010221 alexidine Drugs 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 239000002738 chelating agent Substances 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 239000012929 tonicity agent Substances 0.000 claims 2
- 239000004034 viscosity adjusting agent Substances 0.000 claims 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical group CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 claims 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 229960000686 benzalkonium chloride Drugs 0.000 claims 1
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 claims 1
- 229960001950 benzethonium chloride Drugs 0.000 claims 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims 1
- HHKZCCWKTZRCCL-UHFFFAOYSA-N bis-tris propane Chemical compound OCC(CO)(CO)NCCCNC(CO)(CO)CO HHKZCCWKTZRCCL-UHFFFAOYSA-N 0.000 claims 1
- 229960003168 bronopol Drugs 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- 229960003260 chlorhexidine Drugs 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- 229960002163 hydrogen peroxide Drugs 0.000 claims 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 1
- 229940071676 hydroxypropylcellulose Drugs 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- 229920000609 methyl cellulose Polymers 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 229940066429 octoxynol Drugs 0.000 claims 1
- 229920002113 octoxynol Polymers 0.000 claims 1
- 229960003330 pentetic acid Drugs 0.000 claims 1
- 229920001987 poloxamine Polymers 0.000 claims 1
- -1 polyquaternium-1 Chemical compound 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- MDYZKJNTKZIUSK-UHFFFAOYSA-N tyloxapol Chemical compound O=C.C1CO1.CC(C)(C)CC(C)(C)C1=CC=C(O)C=C1 MDYZKJNTKZIUSK-UHFFFAOYSA-N 0.000 claims 1
- 229960004224 tyloxapol Drugs 0.000 claims 1
- 229920001664 tyloxapol Polymers 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25375700P | 2000-11-29 | 2000-11-29 | |
| PCT/EP2001/013835 WO2002043482A2 (en) | 2000-11-29 | 2001-11-27 | Aqueous disinfecting systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004525087A JP2004525087A (ja) | 2004-08-19 |
| JP2004525087A5 true JP2004525087A5 (enExample) | 2005-12-22 |
| JP4322503B2 JP4322503B2 (ja) | 2009-09-02 |
Family
ID=22961578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002545472A Expired - Fee Related JP4322503B2 (ja) | 2000-11-29 | 2001-11-27 | 水性消毒系 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7419944B2 (enExample) |
| EP (1) | EP1339278B1 (enExample) |
| JP (1) | JP4322503B2 (enExample) |
| KR (1) | KR20030068148A (enExample) |
| CN (1) | CN1477929A (enExample) |
| AR (1) | AR031417A1 (enExample) |
| AT (1) | ATE284138T1 (enExample) |
| AU (1) | AU2002233204A1 (enExample) |
| BR (1) | BR0115693A (enExample) |
| CA (1) | CA2430127C (enExample) |
| DE (1) | DE60107715T2 (enExample) |
| HU (1) | HUP0302161A3 (enExample) |
| MX (1) | MXPA03004816A (enExample) |
| NO (1) | NO20032324L (enExample) |
| TW (1) | TW496745B (enExample) |
| WO (1) | WO2002043482A2 (enExample) |
| ZA (1) | ZA200303628B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004305535A1 (en) * | 2003-12-09 | 2005-07-07 | Alcon, Inc. | Use of organic buffering agents to enhance the antimicrobial activity of pharmaceutical compositions |
| JP4644682B2 (ja) * | 2003-12-09 | 2011-03-02 | アルコン、インコーポレイテッド | 水性組成物の抗微生物活性を強化するためのビスアミンの使用 |
| US20060141059A1 (en) * | 2004-12-27 | 2006-06-29 | Alcon, Inc. | Self-preserved ophthalmic pharmaceutical compositions containing tobramycin |
| EP1998907B1 (en) | 2006-02-28 | 2011-02-16 | Cellular Bioengineering, Inc. | Polymer composition and method for removing contaminates from a substrate |
| US20070287752A1 (en) * | 2006-06-08 | 2007-12-13 | Burke Susan E | Ophthalmic Compositions Comprising A Branched, Glycerol Compound |
| TWI394564B (zh) * | 2006-09-21 | 2013-05-01 | Alcon Res Ltd | 自行保存型水性藥學組成物 |
| WO2008036855A2 (en) * | 2006-09-21 | 2008-03-27 | Alcon Research, Ltd. | Self-preserved aqueous pharmaceutical compositions |
| CN101522171A (zh) * | 2006-09-28 | 2009-09-02 | 爱尔康研究有限公司 | 自身防腐的水性药物组合物 |
| EP2173161A1 (en) * | 2007-06-19 | 2010-04-14 | Cellular Bioengineering, Inc. | Method for treating microorganisms and/or infectious agents |
| WO2008157670A2 (en) * | 2007-06-19 | 2008-12-24 | Cellular Bioengineering, Inc. | Method for protecting substrates and removing contaminants from such substrates |
| TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| BRPI0909738A2 (pt) * | 2008-03-17 | 2015-10-06 | Alcon Res Ltd | composições farmacêuticas aquosas contendo complexos de boratopoliol |
| GB0818869D0 (en) * | 2008-10-15 | 2008-11-19 | Byotrol Plc | Anti-microbial composition |
| TWI489997B (zh) * | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸－多元醇錯合物之水性藥學組成物 |
| EP2742510A1 (en) | 2011-08-11 | 2014-06-18 | Cellular Bioengineering, Inc. | Polymer composition |
| US9132106B2 (en) * | 2013-03-14 | 2015-09-15 | Abbott Medical Optics Inc. | Synergistic ophthalmic compositions for disinfecting contact lenses |
| CN108024532A (zh) * | 2015-07-24 | 2018-05-11 | 泰利福医疗公司 | 用于手术应用的抗微生物组合物 |
| CA3077050A1 (en) | 2017-09-26 | 2019-04-04 | Ecolab Usa Inc. | Acidic/anionic antimicrobial and virucidal compositions and uses thereof |
| WO2020097536A1 (en) * | 2018-11-08 | 2020-05-14 | Chen Hwang Hsing | Tris-substituted biguanide compounds and their uses |
| US12053540B2 (en) | 2018-12-04 | 2024-08-06 | Virox Technologies Inc. | Antimicrobial compositions containing solvents including a C3-C5 N-alkyl-gamma-butyrolactam |
| AU2019391650B2 (en) | 2018-12-04 | 2024-10-03 | Virox Technologies Inc. | C3-C5 N-alkyl-gamma-butyrolactam-containing antimicrobial compositions and uses thereof |
| US12052990B2 (en) | 2018-12-04 | 2024-08-06 | Virox Technologies Inc. | C3-C5 n-alkyl-gamma-butyrolactam containing antimicrobial compositions and methods of using same |
| US12532886B2 (en) | 2018-12-04 | 2026-01-27 | Virox Technologies Inc. | Method of killing microbes using C3-C5 n-alkyl-gamma-butyrolactams and antimicrobial compositions containing same |
| CN114901072B (zh) | 2019-12-16 | 2024-12-17 | 埃科莱布美国股份有限公司 | 阴离子表面活性剂对杀病毒功效的影响 |
| CN115777722B (zh) * | 2022-11-30 | 2024-04-30 | 华中农业大学 | 阿来西定二盐酸盐在抑制植物病原菌的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1432345A (en) | 1972-04-13 | 1976-04-14 | Smith Enphew Research Ltd | Ophthalmic compositions and contact lens disinfecting compo sitions |
| US4758595A (en) | 1984-12-11 | 1988-07-19 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| HU212184B (en) * | 1990-12-27 | 1996-03-28 | Allergan Inc | Method and composition for disinfecting contact-lenses |
| DK172894B1 (da) | 1991-01-03 | 1999-09-27 | Niels Aage Aunsholt | Hæmodialyseapparat |
| US5312749A (en) | 1992-05-12 | 1994-05-17 | The United States Of America As Represented By The Secretary Of Agriculture | Industrial alkaline protease from shipworm bacterium |
| GB9320782D0 (en) | 1993-10-08 | 1993-12-01 | Univ Leeds Innovations Ltd | Stabilising of proteins on solution |
| JP3883739B2 (ja) * | 1998-05-22 | 2007-02-21 | 株式会社メニコン | コンタクトレンズ用殺菌液 |
| US6162393A (en) * | 1998-08-06 | 2000-12-19 | Ndt, Inc. | Contact lens and ophthalmic solutions |
| US7067547B1 (en) * | 1999-11-04 | 2006-06-27 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions comprising imidazole |
| JP2001356307A (ja) * | 2000-06-14 | 2001-12-26 | Menicon Co Ltd | コンタクトレンズ用液 |
| US9492581B2 (en) * | 2000-11-08 | 2016-11-15 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers |
-
2001
- 2001-11-27 CA CA2430127A patent/CA2430127C/en not_active Expired - Lifetime
- 2001-11-27 TW TW090129253A patent/TW496745B/zh not_active IP Right Cessation
- 2001-11-27 KR KR10-2003-7006333A patent/KR20030068148A/ko not_active Withdrawn
- 2001-11-27 EP EP01984771A patent/EP1339278B1/en not_active Expired - Lifetime
- 2001-11-27 BR BR0115693-4A patent/BR0115693A/pt not_active Application Discontinuation
- 2001-11-27 JP JP2002545472A patent/JP4322503B2/ja not_active Expired - Fee Related
- 2001-11-27 WO PCT/EP2001/013835 patent/WO2002043482A2/en not_active Ceased
- 2001-11-27 MX MXPA03004816A patent/MXPA03004816A/es unknown
- 2001-11-27 AR ARP010105503A patent/AR031417A1/es unknown
- 2001-11-27 AU AU2002233204A patent/AU2002233204A1/en not_active Abandoned
- 2001-11-27 DE DE60107715T patent/DE60107715T2/de not_active Expired - Lifetime
- 2001-11-27 CN CNA018197817A patent/CN1477929A/zh active Pending
- 2001-11-27 AT AT01984771T patent/ATE284138T1/de not_active IP Right Cessation
- 2001-11-27 HU HU0302161A patent/HUP0302161A3/hu unknown
- 2001-11-29 US US09/997,099 patent/US7419944B2/en not_active Expired - Lifetime
-
2003
- 2003-05-12 ZA ZA200303628A patent/ZA200303628B/en unknown
- 2003-05-22 NO NO20032324A patent/NO20032324L/no unknown
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