JP2004524810A5 - - Google Patents

Info

Publication number

JP2004524810A5

JP2004524810A5 JP2002527250A JP2002527250A JP2004524810A5 JP 2004524810 A5 JP2004524810 A5 JP 2004524810A5 JP 2002527250 A JP2002527250 A JP 2002527250A JP 2002527250 A JP2002527250 A JP 2002527250A JP 2004524810 A5 JP2004524810 A5 JP 2004524810A5

Authority

JP

Japan

Prior art keywords

amino acid

seq

polypeptide

cripto

full length

Prior art date

2001-09-18

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 150000001413 amino acids Chemical class 0.000 description 61
• 235000001014 amino acid Nutrition 0.000 description 58
• 101000835745 Homo sapiens Teratocarcinoma-derived growth factor 1 Proteins 0.000 description 42
• 102100026404 Teratocarcinoma-derived growth factor 1 Human genes 0.000 description 28
• 229920001184 polypeptide Polymers 0.000 description 24
• 108090000765 processed proteins & peptides Proteins 0.000 description 24
• 102000004196 processed proteins & peptides Human genes 0.000 description 24
• 239000012634 fragment Substances 0.000 description 16
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 10
• 238000006467 substitution reaction Methods 0.000 description 8
• 108010076504 Protein Sorting Signals Proteins 0.000 description 5
• 125000000539 amino acid group Chemical group 0.000 description 5
• DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 4
• 201000010099 disease Diseases 0.000 description 3
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
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• 108091026890 Coding region Proteins 0.000 description 2
• 239000004471 Glycine Substances 0.000 description 2
• QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 2
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• 235000004279 alanine Nutrition 0.000 description 2
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• 229920001059 synthetic polymer Polymers 0.000 description 2
• 230000004568 DNA-binding Effects 0.000 description 1
• 108010070675 Glutathione transferase Proteins 0.000 description 1
• 102000005720 Glutathione transferase Human genes 0.000 description 1
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• HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
• 238000009396 hybridization Methods 0.000 description 1
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• 238000000338 in vitro Methods 0.000 description 1
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