JP2004520409A - 乾燥粉体製剤からの放出の調節 - Google Patents

乾燥粉体製剤からの放出の調節 Download PDF

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Publication number
JP2004520409A
JP2004520409A JP2002567270A JP2002567270A JP2004520409A JP 2004520409 A JP2004520409 A JP 2004520409A JP 2002567270 A JP2002567270 A JP 2002567270A JP 2002567270 A JP2002567270 A JP 2002567270A JP 2004520409 A JP2004520409 A JP 2004520409A
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particles
particle
bioactive agent
weight
microns
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JP2002567270A
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Japanese (ja)
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JP2004520409A5 (enExample
Inventor
バス，スジト，ケイ．
カポネッティ，ジョバンニ
ディーバー，ダニエル，アール．
エルバート，カタリーナ，ジェイ．
ルカシュ，ジェフリー，エス．
リップ，マイケル，エム．
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アドバンスト インハレーション リサーチ，インコーポレイテッド
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Publication of JP2004520409A publication Critical patent/JP2004520409A/ja
Publication of JP2004520409A5 publication Critical patent/JP2004520409A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002567270A 2001-02-23 2002-02-22 乾燥粉体製剤からの放出の調節 Pending JP2004520409A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/792,869 US20010036481A1 (en) 1999-08-25 2001-02-23 Modulation of release from dry powder formulations
PCT/US2002/005629 WO2002067902A2 (en) 2001-02-23 2002-02-22 Modulation of release from dry powder formulations

Publications (2)

Publication Number Publication Date
JP2004520409A true JP2004520409A (ja) 2004-07-08
JP2004520409A5 JP2004520409A5 (enExample) 2005-07-07

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JP2002567270A Pending JP2004520409A (ja) 2001-02-23 2002-02-22 乾燥粉体製剤からの放出の調節

Country Status (6)

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US (2) US20010036481A1 (enExample)
EP (1) EP1370246A2 (enExample)
JP (1) JP2004520409A (enExample)
AU (1) AU2002242253B2 (enExample)
CA (1) CA2438268A1 (enExample)
WO (1) WO2002067902A2 (enExample)

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Publication number Publication date
AU2002242253B2 (en) 2005-04-21
EP1370246A2 (en) 2003-12-17
WO2002067902A2 (en) 2002-09-06
CA2438268A1 (en) 2002-09-06
US20050003003A1 (en) 2005-01-06
WO2002067902A3 (en) 2003-03-13
US20010036481A1 (en) 2001-11-01

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