JP2004520335A - 興奮性アミノ酸レセプターアンタゴニスト - Google Patents
興奮性アミノ酸レセプターアンタゴニスト Download PDFInfo
- Publication number
- JP2004520335A JP2004520335A JP2002554680A JP2002554680A JP2004520335A JP 2004520335 A JP2004520335 A JP 2004520335A JP 2002554680 A JP2002554680 A JP 2002554680A JP 2002554680 A JP2002554680 A JP 2002554680A JP 2004520335 A JP2004520335 A JP 2004520335A
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compound
- alkyl
- acceptable salt
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- AZNNFRBTUPHBIE-WIJBJCKWSA-N CCOC([C@H](C1)N(CC(CC2)CC(C3)C2CN[C@@H]3C(OCC)=O)CC1(F)F)=O Chemical compound CCOC([C@H](C1)N(CC(CC2)CC(C3)C2CN[C@@H]3C(OCC)=O)CC1(F)F)=O AZNNFRBTUPHBIE-WIJBJCKWSA-N 0.000 description 1
- OXQXJYQSWZFDBB-IUCVHNFVSA-N OC([C@H](C1)N(CC(CC2)CC(C3)[C@@H]2CN[C@@H]3C(O)=O)CC1(F)F)=O Chemical compound OC([C@H](C1)N(CC(CC2)CC(C3)[C@@H]2CN[C@@H]3C(O)=O)CC1(F)F)=O OXQXJYQSWZFDBB-IUCVHNFVSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26001401P | 2001-01-05 | 2001-01-05 | |
PCT/US2001/044715 WO2002053561A1 (en) | 2001-01-05 | 2001-12-20 | Excitatory amino acid receptor antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2004520335A true JP2004520335A (ja) | 2004-07-08 |
JP2004520335A5 JP2004520335A5 (no) | 2005-12-22 |
Family
ID=22987455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002554680A Pending JP2004520335A (ja) | 2001-01-05 | 2001-12-20 | 興奮性アミノ酸レセプターアンタゴニスト |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1351955A1 (no) |
JP (1) | JP2004520335A (no) |
KR (1) | KR20030066797A (no) |
CN (1) | CN1484642A (no) |
AR (1) | AR035679A1 (no) |
BR (1) | BR0116672A (no) |
CA (1) | CA2431545A1 (no) |
CZ (1) | CZ20031856A3 (no) |
DZ (1) | DZ3460A1 (no) |
EA (1) | EA200300770A1 (no) |
EC (1) | ECSP034682A (no) |
HR (1) | HRP20030544A2 (no) |
HU (1) | HUP0302528A2 (no) |
IL (1) | IL156138A0 (no) |
MX (1) | MXPA03005981A (no) |
NO (1) | NO20032973L (no) |
NZ (1) | NZ525821A (no) |
PE (1) | PE20020792A1 (no) |
PL (1) | PL361934A1 (no) |
SK (1) | SK8242003A3 (no) |
TW (1) | TW591023B (no) |
WO (1) | WO2002053561A1 (no) |
ZA (1) | ZA200304311B (no) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5284957A (en) * | 1992-09-03 | 1994-02-08 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
JP2002505254A (ja) * | 1998-02-06 | 2002-02-19 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | パロキセチン塩 |
GB9908175D0 (en) * | 1999-04-09 | 1999-06-02 | Lilly Co Eli | Method of treating neurological disorders |
US6566370B1 (en) * | 1999-07-06 | 2003-05-20 | Eli Lilly And Company | Selective iGluR5 receptor antagonists for the treatment of migraine |
-
2001
- 2001-12-20 KR KR10-2003-7008977A patent/KR20030066797A/ko not_active Application Discontinuation
- 2001-12-20 PL PL01361934A patent/PL361934A1/xx not_active Application Discontinuation
- 2001-12-20 EP EP01995980A patent/EP1351955A1/en not_active Withdrawn
- 2001-12-20 CZ CZ20031856A patent/CZ20031856A3/cs unknown
- 2001-12-20 DZ DZ013460A patent/DZ3460A1/fr active
- 2001-12-20 NZ NZ525821A patent/NZ525821A/en unknown
- 2001-12-20 HU HU0302528A patent/HUP0302528A2/hu unknown
- 2001-12-20 CN CNA018217508A patent/CN1484642A/zh active Pending
- 2001-12-20 EA EA200300770A patent/EA200300770A1/ru unknown
- 2001-12-20 CA CA002431545A patent/CA2431545A1/en not_active Abandoned
- 2001-12-20 WO PCT/US2001/044715 patent/WO2002053561A1/en not_active Application Discontinuation
- 2001-12-20 SK SK824-2003A patent/SK8242003A3/sk unknown
- 2001-12-20 IL IL15613801A patent/IL156138A0/xx unknown
- 2001-12-20 JP JP2002554680A patent/JP2004520335A/ja active Pending
- 2001-12-20 BR BR0116672-7A patent/BR0116672A/pt not_active IP Right Cessation
- 2001-12-20 MX MXPA03005981A patent/MXPA03005981A/es unknown
-
2002
- 2002-01-04 TW TW091100071A patent/TW591023B/zh not_active IP Right Cessation
- 2002-01-04 PE PE2002000003A patent/PE20020792A1/es not_active Application Discontinuation
- 2002-01-04 AR ARP020100030A patent/AR035679A1/es not_active Application Discontinuation
-
2003
- 2003-06-02 ZA ZA200304311A patent/ZA200304311B/en unknown
- 2003-06-27 NO NO20032973A patent/NO20032973L/no not_active Application Discontinuation
- 2003-07-03 EC EC2003004682A patent/ECSP034682A/es unknown
- 2003-07-03 HR HR20030544A patent/HRP20030544A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA200304311B (en) | 2004-09-02 |
AR035679A1 (es) | 2004-06-23 |
MXPA03005981A (es) | 2003-09-10 |
HUP0302528A2 (hu) | 2003-11-28 |
NO20032973D0 (no) | 2003-06-27 |
TW591023B (en) | 2004-06-11 |
ECSP034682A (es) | 2003-08-29 |
EA200300770A1 (ru) | 2003-10-30 |
PL361934A1 (en) | 2004-10-18 |
HRP20030544A2 (en) | 2004-08-31 |
NO20032973L (no) | 2003-06-27 |
KR20030066797A (ko) | 2003-08-09 |
WO2002053561A1 (en) | 2002-07-11 |
IL156138A0 (en) | 2003-12-23 |
SK8242003A3 (en) | 2004-01-08 |
CA2431545A1 (en) | 2002-07-11 |
PE20020792A1 (es) | 2002-09-06 |
DZ3460A1 (fr) | 2002-07-11 |
NZ525821A (en) | 2004-07-30 |
CZ20031856A3 (cs) | 2003-09-17 |
BR0116672A (pt) | 2003-09-23 |
EP1351955A1 (en) | 2003-10-15 |
CN1484642A (zh) | 2004-03-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20040831 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20040831 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080325 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20080819 |