|
US20040022788A1
(en)
|
1998-05-19 |
2004-02-05 |
Moser Tammy L. |
Compositions and methods for promoting or inhibiting angiogenesis
|
|
CN1218182C
(zh)
*
|
1999-05-28 |
2005-09-07 |
干细胞技术公司 |
利用免疫玫瑰花结分离细胞的方法
|
|
CN1399562A
(zh)
|
1999-11-28 |
2003-02-26 |
拉卓拉药物公司 |
基于抗体亲和力来治疗狼疮的方法及使用这种方法的筛选方法和组合物
|
|
CA2398466A1
(en)
*
|
2000-01-27 |
2001-08-02 |
Medimmune, Inc. |
Ultra high affinity neutralizing antibodies
|
|
JP2003525061A
(ja)
*
|
2000-03-01 |
2003-08-26 |
メディミューン,インコーポレイテッド |
高効力組換え抗体およびその産生法
|
|
CA2417432C
(en)
*
|
2000-09-01 |
2010-11-02 |
The Center For Blood Research, Inc. |
Modified polypeptides stabilized in a desired conformation and methods for producing same
|
|
US6855493B2
(en)
|
2000-11-28 |
2005-02-15 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
US7179900B2
(en)
*
|
2000-11-28 |
2007-02-20 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
EP1355919B1
(en)
|
2000-12-12 |
2010-11-24 |
MedImmune, LLC |
Molecules with extended half-lives, compositions and uses thereof
|
|
US7658921B2
(en)
*
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
|
US6820011B2
(en)
|
2001-04-11 |
2004-11-16 |
The Regents Of The University Of Colorado |
Three-dimensional structure of complement receptor type 2 and uses thereof
|
|
WO2003016470A2
(en)
*
|
2001-08-10 |
2003-02-27 |
University Of Virginia Patent Foundation |
Enhancing the efficacy of immunotherapies by supplementing with complement
|
|
US20030114405A1
(en)
*
|
2001-08-13 |
2003-06-19 |
Linnik Matthew D. |
Methods of treating systemic lupus erythematosus in individuals having significantly impaired renal function
|
|
US7105135B2
(en)
*
|
2001-10-16 |
2006-09-12 |
Lockheed Martin Corporation |
System and method for large scale detection of hazardous materials in the mail or in other objects
|
|
EP1483383A4
(en)
*
|
2002-02-15 |
2007-10-24 |
Cygene Inc |
METHODS AND COMPOSITIONS FOR THE CLEANING OF PATHOGENS IN VIVO
|
|
WO2003106695A2
(en)
*
|
2002-06-13 |
2003-12-24 |
Cygene, Inc. |
Methods and compositions for in vivo clearance of pathogens
|
|
US7132100B2
(en)
*
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
US7425618B2
(en)
*
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
|
AT413487B
(de)
*
|
2002-08-12 |
2006-03-15 |
Igeneon Krebs Immuntherapie |
Verwendung von antikörpern gegen ein tumor-assoziiertes antigen
|
|
EP1539811A4
(en)
*
|
2002-09-16 |
2006-05-24 |
Elusys Therapeutics Inc |
PREPARATION OF BISPEQIFIC MOLECULES WITH POLYETHYLENE GLYCOL LINKER
|
|
US7550256B2
(en)
*
|
2002-12-13 |
2009-06-23 |
Aurelium Biopharma, Inc. |
Vimentin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
|
|
AU2003302986A1
(en)
*
|
2002-12-13 |
2004-07-09 |
Aurelium Biopharma Inc. |
Nucleophosmin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
|
|
US7670604B2
(en)
|
2002-12-13 |
2010-03-02 |
Aurelium Biopharma, Inc. |
Vimentin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
|
|
AU2003303524A1
(en)
*
|
2002-12-27 |
2004-07-29 |
La Jolla Pharmaceutical Company |
Methods of improving health-related quality of life in individuals with systemic lupus erythematosus
|
|
AU2003300676A1
(en)
*
|
2003-01-03 |
2004-07-29 |
Aurelium Biopharma Inc. |
Hsc70 directed diagnostics and therapeutics for multidrug resistant neoplastic disease
|
|
WO2004080819A2
(en)
*
|
2003-03-14 |
2004-09-23 |
Aurelium Biopharma Inc. |
Triosephosphate isomerase directed diagnostics and therapeutics for multidrug resistant neoplastic disease
|
|
WO2004089422A2
(en)
*
|
2003-03-30 |
2004-10-21 |
La Jolla Pharmaceutical Co. |
Methods of treating and monitoring systemic lupus erythematosus in individuals
|
|
US20090004183A1
(en)
*
|
2004-07-23 |
2009-01-01 |
Taylor Ronald P |
Compositions and Methods for Regulating the Alternative Pathway of Complement
|
|
CA2585891A1
(en)
*
|
2004-10-29 |
2006-05-11 |
Medimmune, Inc. |
Methods of preventing and treating rsv infections and related conditions
|
|
US8420783B2
(en)
*
|
2004-12-08 |
2013-04-16 |
Immunomedics, Inc. |
Method and compositions for immunotherapy of inflammatory and immune-dysregulatory diseases
|
|
US20090196850A1
(en)
|
2005-01-06 |
2009-08-06 |
Novo Nordisk A/S |
Anti-Kir Combination Treatments and Methods
|
|
US20090192077A1
(en)
*
|
2005-04-15 |
2009-07-30 |
Shizuko Sei |
North-2'deoxy -methanocarbathymidines as antiviral agents for treatment of kaposi's sarcoma-associated herpes virus
|
|
US8524453B2
(en)
*
|
2006-02-10 |
2013-09-03 |
The Brigham And Woman's Hospital, Inc. |
Lectin complement pathway assays and related compositions and methods
|
|
JP5250548B2
(ja)
|
2006-06-21 |
2013-07-31 |
エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント |
疾患の治療のための補体h因子の標的化
|
|
US8889632B2
(en)
|
2007-01-31 |
2014-11-18 |
Dana-Farber Cancer Institute, Inc. |
Stabilized p53 peptides and uses thereof
|
|
EP2508531B1
(en)
|
2007-03-28 |
2016-10-19 |
President and Fellows of Harvard College |
Stitched polypeptides
|
|
EP1997830A1
(en)
|
2007-06-01 |
2008-12-03 |
AIMM Therapeutics B.V. |
RSV specific binding molecules and means for producing them
|
|
CA2728739C
(en)
|
2008-06-20 |
2017-07-11 |
Duke University |
Use of human cytomegalovirus antigens to enhance immune responses to cancer cells
|
|
US8775090B2
(en)
|
2008-12-12 |
2014-07-08 |
Medimmune, Llc |
Crystals and structure of a human IgG Fc variant with enhanced FcRn binding
|
|
PL3912643T3
(pl)
|
2009-02-13 |
2023-01-23 |
Immunomedics Inc. |
Immunokoniugaty z połączeniem rozszczepialnym wewnątrzkomórkowo
|
|
JP5871798B2
(ja)
|
2009-07-02 |
2016-03-01 |
エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント |
肝再生を刺激する方法
|
|
WO2011034660A1
(en)
|
2009-09-16 |
2011-03-24 |
Immunomedics, Inc. |
Class i anti-cea antibodies and uses thereof
|
|
CA2774973A1
(en)
|
2009-09-22 |
2011-03-31 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
US8568726B2
(en)
|
2009-10-06 |
2013-10-29 |
Medimmune Limited |
RSV specific binding molecule
|
|
CN102958535A
(zh)
|
2009-11-05 |
2013-03-06 |
亚力史剑桥公司 |
阵发性夜间血红蛋白尿、溶血性贫血和涉及血管内和血管外溶血的疾病状态的治疗
|
|
IN2012DN03354A
(cg-RX-API-DMAC7.html)
|
2009-12-02 |
2015-10-23 |
Immunomedics Inc |
|
|
MX2012013233A
(es)
|
2010-05-14 |
2013-05-20 |
Univ Colorado Regents |
Grupos que apuntan a receptor 2 de complemento (cr2) mejorados.
|
|
BR112012033119A2
(pt)
|
2010-06-22 |
2016-10-25 |
Univ Colorado Regents |
anticorpos para o fragamento c3d do componente do complemento 3.
|
|
US8791121B2
(en)
|
2010-08-12 |
2014-07-29 |
New York University |
Oligooxopiperazines and methods of making and using them
|
|
SI2603600T1
(sl)
|
2010-08-13 |
2019-04-30 |
Aileron Therapeutics, Inc. |
Peptidomimetični makrocikli
|
|
AU2012250924B2
(en)
|
2011-05-02 |
2017-05-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
TW201806968A
(zh)
|
2011-10-18 |
2018-03-01 |
艾利倫治療公司 |
擬肽巨環化合物
|
|
KR102112373B1
(ko)
|
2012-02-15 |
2020-05-18 |
에일러론 테라퓨틱스 인코포레이티드 |
펩티드모방체 마크로사이클
|
|
HK1205454A1
(en)
|
2012-02-15 |
2015-12-18 |
Aileron Therapeutics, Inc. |
Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
|
|
WO2013123511A1
(en)
|
2012-02-16 |
2013-08-22 |
New York University |
Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics
|
|
AU2013302696B9
(en)
|
2012-08-14 |
2018-08-09 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
|
US10413620B2
(en)
|
2012-08-17 |
2019-09-17 |
The Regents Of The University Of Colorado, A Body Corporate |
Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging
|
|
JP2015535212A
(ja)
|
2012-08-17 |
2015-12-10 |
ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト |
補体活性化を検出するための組成物および方法
|
|
WO2014071241A1
(en)
|
2012-11-01 |
2014-05-08 |
Aileron Therapeutics, Inc. |
Disubstituted amino acids and methods of preparation and use thereof
|
|
CN107753954A
(zh)
|
2012-12-13 |
2018-03-06 |
免疫医疗公司 |
功效改进且毒性降低的抗体与sn‑38的免疫缀合物的剂量
|
|
IL312865B2
(en)
*
|
2013-09-11 |
2025-06-01 |
Eagle Biologics Inc |
Liquid protein formulations containing viscosity-lowering agents
|
|
WO2015105973A1
(en)
|
2014-01-08 |
2015-07-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
ANTIBODY TARGETING CELL SURFACE DEPOSITED COMPLEMENT PROTEIN C3d AND USE THEREOF
|
|
ES2978993T3
(es)
|
2014-02-21 |
2024-09-23 |
Ibc Pharmaceuticals Inc |
Terapia de enfermedades mediante la inducción de la respuesta inmunitaria a las células que expresan Trop-2
|
|
CA2935748A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
|
US9580495B2
(en)
|
2014-06-24 |
2017-02-28 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
|
JP2018503595A
(ja)
|
2014-09-24 |
2018-02-08 |
エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. |
ペプチド模倣大環状分子およびその製剤
|
|
BR112017005598A2
(pt)
|
2014-09-24 |
2017-12-12 |
Aileron Therapeutics Inc |
macrociclos peptidomiméticos e usos dos mesmos
|
|
PL3204018T3
(pl)
|
2014-10-07 |
2022-01-03 |
Immunomedics, Inc. |
Neoadiuwantowe zastosowanie koniugatów przeciwciało-lek
|
|
WO2016154058A1
(en)
|
2015-03-20 |
2016-09-29 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles and uses thereof
|
|
EP3286224A4
(en)
|
2015-04-22 |
2018-11-14 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
|
|
PT3313443T
(pt)
|
2015-06-25 |
2023-08-30 |
Immunomedics Inc |
Combinação de anticorpos anti-hla-dr ou anti-trop-2 com inibidores de microtúbulos, inibidores de parp, inibidores de bruton quinase ou inibidores de fosfoinositídeo 3-quinase melhora significativamente o resultado terapêutico no cancro
|
|
PL3316885T3
(pl)
|
2015-07-01 |
2021-12-06 |
Immunomedics, Inc. |
Immunokoniugaty przeciwciało-sn-38 z linkerem cl2a
|
|
US10059741B2
(en)
|
2015-07-01 |
2018-08-28 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
US10023613B2
(en)
|
2015-09-10 |
2018-07-17 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles as modulators of MCL-1
|
|
EP3371211B1
(en)
|
2015-11-04 |
2025-01-01 |
Icahn School of Medicine at Mount Sinai |
Rho-associated protein kinase ("rock") inhibitor for treating tumors and cancer, and identifying candidate subjects for such treatment
|
|
EP3448881B1
(en)
|
2016-04-26 |
2023-06-07 |
Icahn School of Medicine at Mount Sinai |
Treatment of hippo pathway mutant tumors and methods of identifying subjects as candidates for treatment
|
|
EP3571221A2
(en)
|
2017-01-20 |
2019-11-27 |
Juno Therapeutics GmbH |
Cell surface conjugates and related cell compositions and methods
|
|
CN110944651A
(zh)
|
2017-02-08 |
2020-03-31 |
蜻蜓疗法股份有限公司 |
用于自然杀伤细胞激活的多特异性结合蛋白及其治疗癌症的治疗性用途
|
|
EP4273258A3
(en)
|
2017-02-20 |
2024-01-17 |
Dragonfly Therapeutics, Inc. |
Proteins binding her2, nkg2d and cd16
|
|
MX2019012017A
(es)
|
2017-04-07 |
2020-02-12 |
Juno Therapeutics Inc |
Celulas modificadas que expresan antigeno de membrana especifico de prostata (psma) o una forma modificada del mismo y metodos relacionados.
|
|
CA3090244A1
(en)
|
2018-02-08 |
2019-08-15 |
Dragonfly Therapeutics, Inc. |
Antibody variable domains targeting the nkg2d receptor
|
|
MX2020008333A
(es)
|
2018-02-08 |
2020-09-21 |
Dragonfly Therapeutics Inc |
Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales.
|
|
CN112119093A
(zh)
|
2018-02-20 |
2020-12-22 |
蜻蜓治疗公司 |
结合cd33、nkg2d和cd16的多特异性结合蛋白和使用方法
|
|
CA3108427A1
(en)
|
2018-08-08 |
2020-02-13 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
|
|
CN113164570B
(zh)
|
2018-08-08 |
2024-05-14 |
蜻蜓疗法股份有限公司 |
结合nkg2d、cd16和肿瘤相关抗原的蛋白质
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
AU2021268340A1
(en)
|
2020-05-06 |
2022-12-08 |
Dragonfly Therapeutics, Inc. |
Proteins binding NKG2D, CD16 and CLEC12A
|
|
EP4301774A4
(en)
|
2021-03-03 |
2025-08-13 |
Dragonfly Therapeutics Inc |
METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN
|
|
EP4342497A1
(en)
|
2021-05-10 |
2024-03-27 |
Kawasaki Institute of Industrial Promotion |
Antibody having reduced binding affinity for antigen
|
|
WO2025143000A1
(ja)
*
|
2023-12-27 |
2025-07-03 |
東亞合成株式会社 |
C3 rna配列に基づく新規二本鎖rna及びその利用
|