JP2004519418A5 - - Google Patents
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- Publication number
- JP2004519418A5 JP2004519418A5 JP2002511766A JP2002511766A JP2004519418A5 JP 2004519418 A5 JP2004519418 A5 JP 2004519418A5 JP 2002511766 A JP2002511766 A JP 2002511766A JP 2002511766 A JP2002511766 A JP 2002511766A JP 2004519418 A5 JP2004519418 A5 JP 2004519418A5
- Authority
- JP
- Japan
- Prior art keywords
- thyroid hormone
- composition
- compound
- concentration
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000556 agonist Substances 0.000 description 9
- 150000001875 compounds Chemical class 0.000 description 9
- 230000003054 hormonal effect Effects 0.000 description 9
- 210000001685 thyroid gland Anatomy 0.000 description 9
- 239000005495 thyroid hormone Substances 0.000 description 8
- 229940036555 thyroid hormone Drugs 0.000 description 8
- -1 thyroid hormone compound Chemical class 0.000 description 8
- 239000003446 ligand Substances 0.000 description 6
- 102100031241 Thioredoxin reductase 2, mitochondrial Human genes 0.000 description 3
- 108010071769 Thyroid Hormone Receptors beta Proteins 0.000 description 3
- 238000010494 dissociation reaction Methods 0.000 description 3
- 230000005593 dissociations Effects 0.000 description 3
- 108020003175 receptors Proteins 0.000 description 3
- 108091008763 thyroid hormone receptors α Proteins 0.000 description 3
- 230000000699 topical effect Effects 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- PVNIQBQSYATKKL-UHFFFAOYSA-N Glycerol trihexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC PVNIQBQSYATKKL-UHFFFAOYSA-N 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- UOWZUVNAGUAEQC-UHFFFAOYSA-N tiratricol Chemical compound IC1=CC(CC(=O)O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 UOWZUVNAGUAEQC-UHFFFAOYSA-N 0.000 description 1
- PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/617,052 US6380255B1 (en) | 1995-06-07 | 2000-07-14 | Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds |
| PCT/GB2001/003182 WO2002005834A2 (en) | 2000-07-14 | 2001-07-16 | Novel uses for thyroid hormones or thyroid hormone-like agonist compounds for treating dermis conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012049349A Division JP2012144544A (ja) | 2000-07-14 | 2012-03-06 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004519418A JP2004519418A (ja) | 2004-07-02 |
| JP2004519418A5 true JP2004519418A5 (https=) | 2008-10-02 |
Family
ID=24472066
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002511766A Pending JP2004519418A (ja) | 2000-07-14 | 2001-07-16 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
| JP2012049349A Pending JP2012144544A (ja) | 2000-07-14 | 2012-03-06 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012049349A Pending JP2012144544A (ja) | 2000-07-14 | 2012-03-06 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6380255B1 (https=) |
| EP (1) | EP1328265A2 (https=) |
| JP (2) | JP2004519418A (https=) |
| AU (1) | AU2001270831A1 (https=) |
| CA (1) | CA2415285A1 (https=) |
| WO (1) | WO2002005834A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2260992C (en) | 1996-08-20 | 2004-03-09 | The Regents Of The University Of California | Eye treatments using synthetic thyroid hormone compositions |
| FI107018B (fi) * | 2000-04-06 | 2001-05-31 | Ipsat Therapies Oy | Dermatologinen käyttö ja valmiste |
| GB0111314D0 (en) * | 2001-05-09 | 2001-07-04 | Karobio Ab | Dermatological formulations |
| JP4473491B2 (ja) * | 2002-05-28 | 2010-06-02 | 株式会社資生堂 | 毛穴縮小剤 |
| CN1882327A (zh) * | 2003-11-19 | 2006-12-20 | 症变治疗公司 | 含磷的新的拟甲状腺素药 |
| WO2006128058A2 (en) | 2005-05-26 | 2006-11-30 | Metabasis Therapeutics, Inc. | Thyromimetics for the treatment of fatty liver diseases |
| US7919533B2 (en) * | 2004-10-20 | 2011-04-05 | Sal Abraham | Diiodothyroacetic acid and method of use |
| WO2006128056A2 (en) * | 2005-05-26 | 2006-11-30 | Metabasis Therapeutics, Inc. | Novel phosphinic acid-containing thyromimetics |
| WO2007002036A1 (en) * | 2005-06-24 | 2007-01-04 | Thomas Lavin | Tyroid hormone in burn and adipose deposites |
| WO2007059039A1 (en) * | 2005-11-11 | 2007-05-24 | Oregon Health & Science University | Thyroxine derivatives for preconditioning against stroke |
| US7708699B2 (en) * | 2005-11-18 | 2010-05-04 | Daag International, Inc. | Reflexometry and hormone function |
| WO2007149998A2 (en) | 2006-06-21 | 2007-12-27 | Neology, Inc. | Systems and methods for interrogator multiple radio frequency identification enabled documents |
| US20090131380A1 (en) * | 2007-11-16 | 2009-05-21 | Pekka Heino | Novel pharmaceutical composition for topical treatment of skin psoriasis and the treatment method thereof |
| CA3044059A1 (en) | 2016-11-21 | 2018-05-24 | Viking Therapeutics, Inc. | Method of treating glycogen storage disease |
| US11707472B2 (en) | 2017-06-05 | 2023-07-25 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis |
| ES3053674T3 (en) | 2018-03-22 | 2026-01-23 | Viking Therapeutics Inc | Crystalline forms and methods of producing crystalline forms of a compound |
| WO2020117962A1 (en) | 2018-12-05 | 2020-06-11 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis and inflammation |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE515812A (https=) | ||||
| GB782745A (en) | 1953-08-13 | 1957-09-11 | Arthur Alfred Hellbaum | Improvements in or relating to pharmaceutical compositions |
| GB859546A (en) | 1956-05-29 | 1961-01-25 | Arthur Alfred Hellbaum | Composition for treatment of the skin |
| US3090724A (en) * | 1961-01-03 | 1963-05-21 | Baxter Laboratories Inc | Method of treating dermatological conditions |
| FR6435M (https=) * | 1967-02-24 | 1968-11-04 | ||
| FR6656M (https=) * | 1967-02-23 | 1969-01-27 | ||
| FR2139748B1 (https=) | 1971-06-03 | 1974-08-30 | Theranol Lab | |
| FR2153202A1 (en) | 1971-09-24 | 1973-05-04 | Ind Chimique | Triiodothyroacetic acid salts prepn - with metals and organic bases |
| CH622703A5 (en) | 1976-06-10 | 1981-04-30 | Berema Sa | Therapeutic compositions for treating deposits of excess fat and infiltrates causing cellulite |
| FR2357246A1 (fr) | 1976-07-09 | 1978-02-03 | Martinez Gerard | Nouvelles compositions therapeutiques douees d'activite anti-inflammatoire, antalgique et anti-cellulitique |
| CH642851A5 (en) | 1980-02-13 | 1984-05-15 | Berema Sa | Medicinal compositions for the treatment of cellulite |
| FR2501505A1 (fr) | 1981-03-11 | 1982-09-17 | Ana Laboratoires | Nouveaux medicaments destines au traitement des hyperlipidemies et hypercholesterolemies a base d'acide 3,5-diiodo-3'-isopropyl-thyroacetique |
| US5019569A (en) | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
| US4889847A (en) | 1986-11-03 | 1989-12-26 | Ortho Pharmaceutical Corporation | Prevention of glucocorticoid-induced skin atrophy |
| US5118707A (en) | 1990-10-31 | 1992-06-02 | The Procter & Gamble Company | Compositions for regulating skin wrinkles comprising a benzofuran derivative |
| HUT67319A (en) * | 1991-08-30 | 1995-03-28 | Life Medical Sciences Inc | Compositions for treating wounds |
| US5591709A (en) * | 1991-08-30 | 1997-01-07 | Life Medical Sciences, Inc. | Compositions and methods for treating wounds |
| CA2122923C (en) | 1991-11-25 | 1999-01-19 | Roy L. Blank | Compositions for regulating skin wrinkles and/or skin atrophy |
| US5284971A (en) | 1992-07-16 | 1994-02-08 | Syntex (U.S.A.) Inc. | 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents |
| EP0831769B2 (en) * | 1995-06-07 | 2008-07-23 | Lavin, Dr., Thomas N. | Novel uses for thyroid hormones or thyroid hormone-like compounds |
| US6221911B1 (en) * | 1995-06-07 | 2001-04-24 | Karo Bio Ab | Uses for thyroid hormone compounds or thyroid hormone-like compounds |
| US5951989A (en) * | 1997-04-07 | 1999-09-14 | Heymann; Warren R. | Method for the treatment of dry skin |
| GB9713739D0 (en) * | 1997-06-27 | 1997-09-03 | Karobio Ab | Thyroid receptor ligands |
-
2000
- 2000-07-14 US US09/617,052 patent/US6380255B1/en not_active Expired - Lifetime
-
2001
- 2001-07-16 EP EP01949712A patent/EP1328265A2/en not_active Withdrawn
- 2001-07-16 WO PCT/GB2001/003182 patent/WO2002005834A2/en not_active Ceased
- 2001-07-16 AU AU2001270831A patent/AU2001270831A1/en not_active Abandoned
- 2001-07-16 JP JP2002511766A patent/JP2004519418A/ja active Pending
- 2001-07-16 CA CA002415285A patent/CA2415285A1/en not_active Abandoned
-
2002
- 2002-02-25 US US10/081,397 patent/US20020123521A1/en not_active Abandoned
-
2012
- 2012-03-06 JP JP2012049349A patent/JP2012144544A/ja active Pending
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