JP2004512815A5 - - Google Patents
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- Publication number
- JP2004512815A5 JP2004512815A5 JP2001548133A JP2001548133A JP2004512815A5 JP 2004512815 A5 JP2004512815 A5 JP 2004512815A5 JP 2001548133 A JP2001548133 A JP 2001548133A JP 2001548133 A JP2001548133 A JP 2001548133A JP 2004512815 A5 JP2004512815 A5 JP 2004512815A5
- Authority
- JP
- Japan
- Prior art keywords
- spacer
- epitope
- hla
- amino acid
- polyepitope construct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 14
- -1 spacer amino acids Chemical class 0.000 claims 8
- 125000006850 spacer group Chemical group 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 125000000539 amino acid group Chemical group 0.000 claims 3
- 230000037361 pathway Effects 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 125000000729 N-terminal amino-acid group Chemical group 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17339099P | 1999-12-28 | 1999-12-28 | |
| PCT/US2000/035568 WO2001047541A1 (en) | 1999-12-28 | 2000-12-28 | Optimized minigenes and peptides encoded thereby |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011056001A Division JP5628716B2 (ja) | 1999-12-28 | 2011-03-14 | 最適化されたミニ遺伝子及びそれによってコードされるペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004512815A JP2004512815A (ja) | 2004-04-30 |
| JP2004512815A5 true JP2004512815A5 (https=) | 2005-09-15 |
Family
ID=22631795
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001548133A Pending JP2004512815A (ja) | 1999-12-28 | 2000-12-28 | 最適化されたミニ遺伝子およびそれによってコードされるペプチド |
| JP2011056001A Expired - Fee Related JP5628716B2 (ja) | 1999-12-28 | 2011-03-14 | 最適化されたミニ遺伝子及びそれによってコードされるペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011056001A Expired - Fee Related JP5628716B2 (ja) | 1999-12-28 | 2011-03-14 | 最適化されたミニ遺伝子及びそれによってコードされるペプチド |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1242108B1 (https=) |
| JP (2) | JP2004512815A (https=) |
| KR (1) | KR100838507B1 (https=) |
| CN (1) | CN1437476A (https=) |
| AT (1) | ATE366582T1 (https=) |
| AU (1) | AU780064B2 (https=) |
| BR (1) | BR0017052B1 (https=) |
| CA (1) | CA2394748A1 (https=) |
| DE (1) | DE60035523T2 (https=) |
| DK (1) | DK1242108T3 (https=) |
| ES (1) | ES2288885T3 (https=) |
| HK (1) | HK1048068B (https=) |
| MX (1) | MXPA02006554A (https=) |
| WO (1) | WO2001047541A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7462354B2 (en) * | 1999-12-28 | 2008-12-09 | Pharmexa Inc. | Method and system for optimizing minigenes and peptides encoded thereby |
| AU2002950183A0 (en) * | 2002-07-12 | 2002-09-12 | The Council Of The Queensland Institute Of Medical Research | Expression of hydrophobic proteins |
| WO2004031210A2 (en) | 2002-10-03 | 2004-04-15 | Epimmune Inc. | Optimized multi-epitope constructs and uses thereof |
| CA2500715A1 (en) * | 2002-10-03 | 2004-04-15 | Epimmune Inc. | Hla binding peptides and their uses |
| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| EP1687022A4 (en) * | 2003-11-12 | 2008-02-13 | Medical Res Council | RENTA: HIV IMMUNOGEN, AND USES OF RENTA |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| US9511134B2 (en) | 2006-05-18 | 2016-12-06 | Epimmune Inc. | Inducing immune responses to influenza virus using polypeptide and nucleic acid compositions |
| EP2391635B1 (en) | 2009-01-28 | 2017-04-26 | Epimmune Inc. | Pan-dr binding polypeptides and uses thereof |
| GB0905519D0 (en) * | 2009-03-31 | 2009-05-13 | Biofortuna Ltd | Assay method and device |
| HRP20211595T1 (hr) | 2011-05-24 | 2022-01-21 | BioNTech SE | Individualizirana cjepiva protiv raka |
| WO2013143555A1 (en) | 2012-03-26 | 2013-10-03 | Biontech Ag | Rna formulation for immunotherapy |
| CA2889064A1 (en) | 2012-10-19 | 2014-04-24 | The Council Of The Queensland Institute Of Medical Research | Improved human herpesvirus immunotherapy |
| WO2014082729A1 (en) | 2012-11-28 | 2014-06-05 | Biontech Ag | Individualized vaccines for cancer |
| WO2014180490A1 (en) | 2013-05-10 | 2014-11-13 | Biontech Ag | Predicting immunogenicity of t cell epitopes |
| WO2016045732A1 (en) | 2014-09-25 | 2016-03-31 | Biontech Rna Pharmaceuticals Gmbh | Stable formulations of lipids and liposomes |
| WO2016128060A1 (en) | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| WO2017059902A1 (en) | 2015-10-07 | 2017-04-13 | Biontech Rna Pharmaceuticals Gmbh | 3' utr sequences for stabilization of rna |
| CN105254719B (zh) * | 2015-10-21 | 2018-07-13 | 黑龙江八一农垦大学 | 金黄色葡萄球菌trap蛋白的cd4+t细胞表位鉴定及其重组表位疫苗 |
| MX2019013259A (es) | 2017-05-08 | 2020-01-13 | Gritstone Oncology Inc | Vectores de neoantigeno de alfavirus. |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| EP3744847A4 (en) * | 2018-01-22 | 2021-12-08 | Japan as Represented by The Director-General of National Institute of Infectious Diseases | SELECTIVE CD8 POSITIVE T CELL INDUCING VACCINE ANTIGEN |
| CN112368386A (zh) * | 2018-05-23 | 2021-02-12 | 磨石肿瘤生物技术公司 | 共有抗原 |
| MX2021014525A (es) | 2019-05-30 | 2022-03-17 | Gritstone Bio Inc | Adenovirus modificados. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2195642A1 (en) * | 1994-07-27 | 1996-02-08 | Andreas Suhrbier | Polyepitope vaccines |
| JP4108126B2 (ja) * | 1996-04-26 | 2008-06-25 | リュクスウニヴェルシテート テ レイデン | Ｔ細胞ペプチド・エピトープの選択と産生方法および選択したエピトープを組込むワクチン |
| CA2250723C (en) * | 1996-05-24 | 2012-07-17 | Chiron Corporation | Multiple epitope fusion protein |
| GB9711957D0 (en) * | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| GB9808932D0 (en) * | 1998-04-27 | 1998-06-24 | Chiron Spa | Polyepitope carrier protein |
| CA2685270C (en) * | 1998-05-13 | 2014-07-29 | Pharmexa Inc. | Expression vectors for stimulating an immune response and methods of using the same |
-
2000
- 2000-12-28 MX MXPA02006554A patent/MXPA02006554A/es not_active Application Discontinuation
- 2000-12-28 AT AT00989585T patent/ATE366582T1/de active
- 2000-12-28 DK DK00989585T patent/DK1242108T3/da active
- 2000-12-28 HK HK03100192.3A patent/HK1048068B/en not_active IP Right Cessation
- 2000-12-28 DE DE60035523T patent/DE60035523T2/de not_active Expired - Lifetime
- 2000-12-28 WO PCT/US2000/035568 patent/WO2001047541A1/en not_active Ceased
- 2000-12-28 JP JP2001548133A patent/JP2004512815A/ja active Pending
- 2000-12-28 CN CN00819182A patent/CN1437476A/zh active Pending
- 2000-12-28 ES ES00989585T patent/ES2288885T3/es not_active Expired - Lifetime
- 2000-12-28 EP EP00989585A patent/EP1242108B1/en not_active Expired - Lifetime
- 2000-12-28 CA CA002394748A patent/CA2394748A1/en not_active Abandoned
- 2000-12-28 BR BRPI0017052-6B1A patent/BR0017052B1/pt not_active IP Right Cessation
- 2000-12-28 AU AU26075/01A patent/AU780064B2/en not_active Ceased
- 2000-12-28 KR KR1020027008507A patent/KR100838507B1/ko not_active Expired - Fee Related
-
2011
- 2011-03-14 JP JP2011056001A patent/JP5628716B2/ja not_active Expired - Fee Related
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