JP2004511426A - 活性化血管部位に関連する陽イオン性の診断薬、画像化剤、および治療薬 - Google Patents

活性化血管部位に関連する陽イオン性の診断薬、画像化剤、および治療薬 Download PDF

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JP2004511426A
JP2004511426A JP2001579774A JP2001579774A JP2004511426A JP 2004511426 A JP2004511426 A JP 2004511426A JP 2001579774 A JP2001579774 A JP 2001579774A JP 2001579774 A JP2001579774 A JP 2001579774A JP 2004511426 A JP2004511426 A JP 2004511426A
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JP2004511426A5 (enExample
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シュルツ　ブリタ
ザウアー　ビルギータ
デリアン　マルク
ミヒャエリス　ウーヴェ
テイフェル　ミヒャエル
ナウジョクス　クルト　ダブリュ．
ビロ　クラウディア
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ミュンヘン　バイオテク　アーゲー
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
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    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
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    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
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    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
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    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
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    • A61K49/0017—Fluorescence in vivo
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    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
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    • A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
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    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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JP2001579774A 2000-05-03 2001-05-03 活性化血管部位に関連する陽イオン性の診断薬、画像化剤、および治療薬 Pending JP2004511426A (ja)

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US20167300P 2000-05-03 2000-05-03
PCT/IB2001/001206 WO2001082899A2 (en) 2000-05-03 2001-05-03 Cationic diagnostic, imaging and therapeutic agents associated with activated vascular sites

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US (1) US20020034537A1 (enExample)
EP (1) EP1278512A2 (enExample)
JP (1) JP2004511426A (enExample)
AU (2) AU2001266272B2 (enExample)
CA (1) CA2406650C (enExample)
CZ (1) CZ20023913A3 (enExample)
HU (1) HUP0301835A2 (enExample)
MX (1) MXPA02010801A (enExample)
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JP2005535730A (ja) * 2002-06-26 2005-11-24 メディゲーネ オンコロギー ゲゼルシャフト ミット ベシュレンクテル ハフツング 脂肪親和性化合物から成る陽イオン性リポソームの製法
WO2006028129A1 (ja) * 2004-09-10 2006-03-16 Toray Industries, Inc. 医薬品製剤
JP2009512712A (ja) * 2005-10-20 2009-03-26 ジョージタウン・ユニバーシティ 癌の早期ｍｒｉ検出を改善するための腫瘍標的化ナノ送達系
JP2012526843A (ja) * 2009-05-15 2012-11-01 バクスター・インターナショナル・インコーポレイテッド 薬物送達のための組成物および方法
US8562991B2 (en) 2008-09-26 2013-10-22 Chugai Seiyaku Kabushiki Kaisha Antibody molecules that bind to IL-6 receptor
US8575317B2 (en) 2007-12-05 2013-11-05 Chugai Seiyaku Kabushiki Kaisha Anti-NR10 antibody and use thereof
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