JP2004504379A5 - - Google Patents
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- Publication number
- JP2004504379A5 JP2004504379A5 JP2002514092A JP2002514092A JP2004504379A5 JP 2004504379 A5 JP2004504379 A5 JP 2004504379A5 JP 2002514092 A JP2002514092 A JP 2002514092A JP 2002514092 A JP2002514092 A JP 2002514092A JP 2004504379 A5 JP2004504379 A5 JP 2004504379A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrrolidine
- carboxylic acid
- mercapto
- alkyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00114949 | 2000-07-19 | ||
| PCT/EP2001/007951 WO2002008185A1 (en) | 2000-07-19 | 2001-07-10 | Pyrrolidine derivatives as metalloprotease inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004504379A JP2004504379A (ja) | 2004-02-12 |
| JP2004504379A5 true JP2004504379A5 (https=) | 2005-02-24 |
| JP3983663B2 JP3983663B2 (ja) | 2007-09-26 |
Family
ID=8169226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002514092A Expired - Lifetime JP3983663B2 (ja) | 2000-07-19 | 2001-07-10 | メタロプロテアーゼインヒビターとしてのピロリジン誘導体 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20020040146A1 (https=) |
| EP (1) | EP1303486A1 (https=) |
| JP (1) | JP3983663B2 (https=) |
| KR (1) | KR100613196B1 (https=) |
| CN (1) | CN100406439C (https=) |
| AR (1) | AR037990A1 (https=) |
| AU (2) | AU2001278479B2 (https=) |
| BR (1) | BR0112655A (https=) |
| CA (1) | CA2415740A1 (https=) |
| MX (1) | MXPA03000368A (https=) |
| PA (1) | PA8522301A1 (https=) |
| PE (1) | PE20020333A1 (https=) |
| UY (1) | UY26846A1 (https=) |
| WO (1) | WO2002008185A1 (https=) |
| ZA (1) | ZA200300170B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3983663B2 (ja) * | 2000-07-19 | 2007-09-26 | エフ．ホフマン−ラ ロシュ アーゲー | メタロプロテアーゼインヒビターとしてのピロリジン誘導体 |
| US7405234B2 (en) * | 2002-05-17 | 2008-07-29 | Bristol-Myers Squibb Company | Bicyclic modulators of androgen receptor function |
| EP1558591B1 (en) | 2002-10-07 | 2014-05-07 | The Regents of The University of California | Modulation of anxiety through blockade of anandamide hydrolysis |
| US7388027B2 (en) * | 2004-03-04 | 2008-06-17 | Bristol-Myers Squibb Company | Bicyclic compounds as modulators of androgen receptor function and method |
| CN101376656A (zh) * | 2007-08-30 | 2009-03-04 | 山东轩竹医药科技有限公司 | 培南衍生物 |
| JP2011517313A (ja) | 2007-12-11 | 2011-06-02 | ビアメト ファーマシューティカルズ，インク． | 金属結合部分を標的化部分と組み合わせて使用する金属酵素阻害剤 |
| WO2010028051A2 (en) * | 2008-09-03 | 2010-03-11 | Florida State University Research Foundation, Inc. | Substituted heterocyclic mercaptosulfonamide metalloprotease inhibitors |
| WO2017004485A1 (en) | 2015-07-02 | 2017-01-05 | Raptor Pharmaceuticals Inc. | Ado-resistant cysteamine analogs and uses thereof |
| BR112020014561A2 (pt) * | 2018-01-17 | 2020-12-08 | Migal - Galilee Research Institute Ltd. | Nibidores inovadores da via metabólica da metionina |
| CN111825582B (zh) * | 2020-08-12 | 2022-04-08 | 江西理工大学 | 一种以芳基磺酰氯为硫源合成β-硫代羰基化合物的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0182213B1 (en) * | 1984-11-08 | 1990-09-26 | Sumitomo Pharmaceuticals Company, Limited | Carbapenem compounds and production thereof |
| US4925838A (en) * | 1988-03-18 | 1990-05-15 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
| US5317016A (en) * | 1991-08-20 | 1994-05-31 | Shionogi Seiyaku Kabushiki Kaisha | Pyrrolidylthiocarbapenem derivative |
| GB9301276D0 (en) * | 1993-01-22 | 1993-03-17 | Fujisawa Pharmaceutical Co | Bicyclic compounds and their preparation |
| AU680736B2 (en) * | 1994-02-25 | 1997-08-07 | Banyu Pharmaceutical Co., Ltd. | Carbapenem derivative |
| IL125453A0 (en) * | 1996-02-13 | 1999-03-12 | Abbott Lab | 4-(Benzo-1,3-dioxylyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists |
| RU2221782C2 (ru) * | 1996-08-28 | 2004-01-20 | Дзе Проктер Энд Гэмбл Компани | Замещенные циклические аминовые ингибиторы металлопротеаз |
| BR9712792A (pt) * | 1996-08-28 | 1999-12-14 | Procter & Gamble | Inibidores de metaloprotease bidentada. |
| JP3983663B2 (ja) * | 2000-07-19 | 2007-09-26 | エフ．ホフマン−ラ ロシュ アーゲー | メタロプロテアーゼインヒビターとしてのピロリジン誘導体 |
| MXPA03000223A (es) * | 2000-07-19 | 2003-06-06 | Hoffmann La Roche | Derivados de pirrolidina como inhibidores de la enzima conversor de endotelina. |
-
2001
- 2001-07-10 JP JP2002514092A patent/JP3983663B2/ja not_active Expired - Lifetime
- 2001-07-10 AU AU2001278479A patent/AU2001278479B2/en not_active Ceased
- 2001-07-10 AU AU7847901A patent/AU7847901A/xx active Pending
- 2001-07-10 MX MXPA03000368A patent/MXPA03000368A/es not_active Application Discontinuation
- 2001-07-10 WO PCT/EP2001/007951 patent/WO2002008185A1/en not_active Ceased
- 2001-07-10 KR KR1020037000790A patent/KR100613196B1/ko not_active Expired - Fee Related
- 2001-07-10 CA CA002415740A patent/CA2415740A1/en not_active Abandoned
- 2001-07-10 BR BR0112655-5A patent/BR0112655A/pt not_active IP Right Cessation
- 2001-07-10 CN CNB018130534A patent/CN100406439C/zh not_active Expired - Fee Related
- 2001-07-10 EP EP01956523A patent/EP1303486A1/en not_active Withdrawn
- 2001-07-16 PA PA20018522301A patent/PA8522301A1/es unknown
- 2001-07-17 PE PE2001000719A patent/PE20020333A1/es not_active Application Discontinuation
- 2001-07-17 UY UY26846A patent/UY26846A1/es not_active Application Discontinuation
- 2001-07-17 AR ARP010103415A patent/AR037990A1/es not_active Application Discontinuation
- 2001-07-17 US US09/906,980 patent/US20020040146A1/en not_active Abandoned
-
2003
- 2003-01-07 ZA ZA200300170A patent/ZA200300170B/en unknown
- 2003-02-25 US US10/373,622 patent/US6790860B2/en not_active Expired - Fee Related
-
2004
- 2004-06-30 US US10/881,427 patent/US7189756B2/en not_active Expired - Fee Related
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