JP2004504340A5 - - Google Patents

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JP2004504340A5
JP2004504340A5 JP2002513443A JP2002513443A JP2004504340A5 JP 2004504340 A5 JP2004504340 A5 JP 2004504340A5 JP 2002513443 A JP2002513443 A JP 2002513443A JP 2002513443 A JP2002513443 A JP 2002513443A JP 2004504340 A5 JP2004504340 A5 JP 2004504340A5
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JP
Japan
Prior art keywords
microparticles
skin surface
subject
transglutaminase
bind
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Pending
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JP2002513443A
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JP2004504340A (ja
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Priority claimed from US09/620,783 external-priority patent/US6958148B1/en
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Publication of JP2004504340A publication Critical patent/JP2004504340A/ja
Publication of JP2004504340A5 publication Critical patent/JP2004504340A5/ja
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【特許請求の範囲】
【請求項1】 対象の皮膚表面に微小粒子を結合させるための対象の処置方法であって、
内因性トランスグルタミナーゼの存在下で、微小粒子を皮膚表面に結合させるのに十分な量で、表面利用性トランスグルタミナーゼ基質反応基を有する微小粒子を皮膚表面に接触させるステップと、
微小粒子の層が皮膚表面に共有結合するのに十分な時間、微小粒子を皮膚表面に接触させたままとするステップとを含む、前記方法。




JP2002513443A 2000-07-21 2001-07-19 微小粒子を用いる用剤の結合 Pending JP2004504340A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/620,783 US6958148B1 (en) 1998-01-20 2000-07-21 Linkage of agents to body tissue using microparticles and transglutaminase
PCT/US2001/022681 WO2002007707A2 (en) 2000-07-21 2001-07-19 Linkage of agents using microparticles

Publications (2)

Publication Number Publication Date
JP2004504340A JP2004504340A (ja) 2004-02-12
JP2004504340A5 true JP2004504340A5 (ja) 2008-09-04

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JP2002513443A Pending JP2004504340A (ja) 2000-07-21 2001-07-19 微小粒子を用いる用剤の結合

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US (2) US6958148B1 (ja)
EP (1) EP1303260A2 (ja)
JP (1) JP2004504340A (ja)
AU (1) AU2002224524A1 (ja)
CA (1) CA2415345A1 (ja)
WO (1) WO2002007707A2 (ja)

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