AU2002224524A1 - Linkage of agents using microparticles - Google Patents

Linkage of agents using microparticles

Info

Publication number
AU2002224524A1
AU2002224524A1 AU2002224524A AU2452402A AU2002224524A1 AU 2002224524 A1 AU2002224524 A1 AU 2002224524A1 AU 2002224524 A AU2002224524 A AU 2002224524A AU 2452402 A AU2452402 A AU 2452402A AU 2002224524 A1 AU2002224524 A1 AU 2002224524A1
Authority
AU
Australia
Prior art keywords
microparticles
linkage
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002224524A
Inventor
Bruce J. Compton
George D. Corey
Philippe Dijan
Howard Green
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pericor Science Inc
Original Assignee
Pericor Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pericor Science Inc filed Critical Pericor Science Inc
Publication of AU2002224524A1 publication Critical patent/AU2002224524A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/94—Involves covalent bonding to the substrate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
AU2002224524A 2000-07-21 2001-07-19 Linkage of agents using microparticles Abandoned AU2002224524A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/620,783 2000-07-21
US09/620,783 US6958148B1 (en) 1998-01-20 2000-07-21 Linkage of agents to body tissue using microparticles and transglutaminase
PCT/US2001/022681 WO2002007707A2 (en) 2000-07-21 2001-07-19 Linkage of agents using microparticles

Publications (1)

Publication Number Publication Date
AU2002224524A1 true AU2002224524A1 (en) 2002-02-05

Family

ID=24487368

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002224524A Abandoned AU2002224524A1 (en) 2000-07-21 2001-07-19 Linkage of agents using microparticles

Country Status (6)

Country Link
US (2) US6958148B1 (en)
EP (1) EP1303260A2 (en)
JP (1) JP2004504340A (en)
AU (1) AU2002224524A1 (en)
CA (1) CA2415345A1 (en)
WO (1) WO2002007707A2 (en)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69310339T2 (en) 1993-02-19 1997-08-21 Howard Green Preparations that contain corneocyte proteins
US6958148B1 (en) * 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
US6821509B2 (en) * 2000-04-14 2004-11-23 Cosmetica, Inc. Nanoscopic hair care products
GB0115320D0 (en) * 2001-06-22 2001-08-15 Univ Nottingham Matrix
WO2003022962A2 (en) * 2001-09-13 2003-03-20 Ansell Healthcare Products, Inc. Microencapsulation coating for gloves
FR2838640B1 (en) * 2002-04-19 2006-02-24 Oreal COSMETIC COMPOSITION COMPRISING A COSMETIC ACTIVE AND A FIXED EXOGENOUS LIGAND-RECEPTOR SYSTEM COMPRISING HAIR COVALENT AND HAIR PROCESSING METHOD USING THE SAME
IL165910A0 (en) * 2002-07-03 2006-01-15 Pericor Science Inc Compositions of hyaluronic acid and methods of use
MY140194A (en) * 2003-07-16 2009-11-30 Leo Pharma As Novel fusidic acid derivatives
US7309482B2 (en) * 2003-09-08 2007-12-18 E.I. Du Pont De Nemours And Company Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner
FR2870741B1 (en) * 2004-05-25 2008-03-14 Coletica Sa HYDRATED LAMELLAR OR LIPOSOME PHASE CONTAINING A FATTY MONOAMINE OR A CATIONIC POLYMER PROMOTING INTERCELLULAR PENETRATION AND A COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME.
US20070108418A1 (en) * 2005-08-09 2007-05-17 Soane Laboratories, Llc Hair hold formulations
UA100841C2 (en) 2006-02-21 2013-02-11 Мэри Кей, Инк. Normal;heading 1;heading 2;heading 3;STABLE VITAMIN C COMPOSITIONS
US20070225213A1 (en) * 2006-03-23 2007-09-27 Kosak Matthew K Nucleic acid carriers for delivery of therapeutic agents
US20080145323A1 (en) * 2006-09-07 2008-06-19 Epiderma Pet, Llc Formulation and method for a sunblock for animals
WO2008056623A1 (en) * 2006-11-09 2008-05-15 Daiichi Sankyo Company, Limited Composition for introduction of nucleic acid
WO2008156559A2 (en) * 2007-06-01 2008-12-24 Chx Technologies, Inc. Topical dental solution of chlorhexidine in sumatra benzoin bp/ep and methods of manufacturing and evaluating same
WO2009002800A1 (en) * 2007-06-22 2008-12-31 Aki, Inc. D/B/A Arcade Marketing, Inc. Cationic, energy-cured varnish with microcapsules
US8029771B2 (en) 2007-06-29 2011-10-04 Mary Kay Inc. Guar gum containing compounds
FR2918271B1 (en) * 2007-07-03 2009-11-13 Oreal COSMETIC COMPOSITION COMPRISING A SILICONE POLYMER AND A TACKIFYING RESIN HAVING CERTAIN ELASTICITY
EP2022467A1 (en) * 2007-08-07 2009-02-11 KPSS-Kao Professional Salon Services GmbH Two-phase composition for conditioning hair
US20090175945A1 (en) * 2008-01-08 2009-07-09 Jie Zhang Systems, Methods, and Formulations for Topically Treating Nail Fungal Infections and Nail Psoriasis
US20090202581A1 (en) * 2008-02-12 2009-08-13 Nathalie Schlemer Cosmetic formulation
KR101683042B1 (en) 2008-04-04 2016-12-06 포사이트 비젼4, 인크. Therapeutic device for pain management and vision
EP2355785A4 (en) 2008-12-09 2014-08-13 Oréal Sa L Transfer-resistant emulsion containing a surfactant
US9308396B2 (en) 2008-12-16 2016-04-12 L'oreal Transfer-resistant and long wear foundation in emulsion form containing oil absorbing powders
WO2010077940A2 (en) 2008-12-16 2010-07-08 Hy Si Bui Water-insoluble reaction product of a polyamine and an oil-soluble high carbon polar modified polymer
BRPI1008602A8 (en) * 2009-02-18 2018-01-02 Eyeon Particle Sciences Llc use of bi-functional copolymer for ophthalmic and other topical and local applications
EP2236520A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Stabilizing composition for immobilized biomolecules
US8388991B2 (en) * 2009-05-01 2013-03-05 Chattem, Inc. Moisturizing antimicrobial composition
EP2446461A2 (en) * 2009-06-24 2012-05-02 David W. Cunningham Incandescent lamp incorporating reflective filament supports and method for making it
US8828366B2 (en) * 2009-06-29 2014-09-09 L'oreal Hydrating cream foundation in emulsion form
US8597626B2 (en) * 2009-06-29 2013-12-03 L'oreal Long wear, waterproof mascara composition with water washability
US8652451B2 (en) * 2009-06-29 2014-02-18 L'oreal Composition comprising a sugar silicone surfactant and a oil-soluble polar modified polymer
ES2662670T3 (en) 2009-06-29 2018-04-09 L'oreal S.A. Composition comprising a polyol and an oil soluble polar modified polymer
US8663667B2 (en) 2009-06-29 2014-03-04 L'oreal Refreshing cream foundation in gel form
EP2269569A3 (en) 2009-06-29 2014-04-23 L'oreal S.A. Composition containing a polyol and a reaction product
US8663609B2 (en) * 2009-06-29 2014-03-04 L'oreal Composition comprising a polyol, a sugar silicone surfactant and a oil-soluble polar modified polymer
US8470304B2 (en) 2009-08-04 2013-06-25 Avidas Pharmaceuticals Llc Therapeutic vitamin D sun-protecting formulations and methods for their use
US9498385B2 (en) 2009-10-23 2016-11-22 Nexisvision, Inc. Conformable therapeutic shield for vision and pain
WO2011050327A1 (en) 2009-10-23 2011-04-28 Forsight Labs Llc Corneal denervation for treatment of ocular pain
EA015599B1 (en) * 2009-11-11 2011-10-31 Открытое Акционерное Общество "Верофарм" Cosmetic agents with antimicrobial properties
MX351010B (en) * 2010-02-04 2017-09-28 Isp Investments Inc Self adapting polymers for anhydrous sunscreen formulations.
FR2959230B1 (en) * 2010-04-27 2016-03-25 Chanel Parfums Beaute POLYPEPTIDE EXPRESSED IN CORNEA LAYER AND USE THEREOF
US20170260235A1 (en) 2010-04-27 2017-09-14 Chanel Parfums Beaute Polypeptide expressed in the stratum corneum and use thereof
US20110280818A1 (en) * 2010-05-14 2011-11-17 L'oreal S.A. Compositions containing hyperbranched polyol and tackifier
PL2654474T3 (en) * 2010-12-22 2016-06-30 Avon Prod Inc Cosmetic adhesive composition
US8747868B2 (en) 2010-12-30 2014-06-10 L'oreal Reaction product of a polar modified polymer and an alkoxysilane and a composition containing the reaction product
US20120237466A1 (en) * 2011-03-18 2012-09-20 James Graham Photo-filtering composition for hair and scalp
EP2696677B1 (en) 2011-04-13 2021-08-11 BioSafe Technologies, Inc. Insecticide, insect repellant and anti-irritation composition
DE102011087320A1 (en) * 2011-11-29 2013-05-29 Henkel Ag & Co. Kgaa Novel combination of active ingredients for efficient anti-wrinkle action
US8992895B2 (en) * 2012-12-19 2015-03-31 L'oreal Sunscreen compositions
JP2016511747A (en) 2013-01-04 2016-04-21 マサチューセッツ インスティテュート オブ テクノロジー Drug delivery to tissues based on nanoparticle surface binding
CA2916885A1 (en) 2013-06-26 2014-12-31 Nexisvision, Inc. Contact lenses for refractive correction
BR112016000585A2 (en) 2013-07-11 2018-03-20 Novartis Ag site-specific chemoenzymatic protein modifications
WO2015066717A1 (en) 2013-11-04 2015-05-07 BioPharmX, Inc. Dosage form comprising an active ingredient and a plurality of solid porous microcarriers
CN103655335B (en) * 2013-12-11 2016-03-02 彭再辉 A kind of hair washing for child is taken a shower two-in-one compositions
US20160051723A1 (en) * 2014-08-21 2016-02-25 Gregory J. Pomrink Bioresorbable tissue repair composition
EP3324880A4 (en) * 2015-07-22 2019-03-13 Cao Group, Inc. Dental treatment films incorporating unmixed reactive ingredients
EP3439676B1 (en) 2016-04-04 2021-06-09 Omeza LLC Fish oil topical composition
CA3029391C (en) 2016-07-06 2024-01-02 Eyeon Particle Sciences Llc Bi-functional co-polymer use for ophthalmic and other topical and local applications
US10085926B2 (en) * 2017-01-26 2018-10-02 Anise Cosmetics, LLC Nail polish remover compositions and methods
US10433554B2 (en) 2017-05-01 2019-10-08 Ohio State Innovation Foundation Deodorizing compounds, compositions, and methods for repelling insects
WO2020018888A1 (en) 2018-07-20 2020-01-23 The Board Of Regents Of The University Of Oklahoma Antimicrobial peptides and methods of use

Family Cites Families (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3867365A (en) 1970-08-05 1975-02-18 Kremers Urban Co Penicilloyl-polylysine conjugates having dextro-rotary optical activity, and methods for their preparation and use
LU65552A1 (en) 1972-06-20 1973-12-27
US3979508A (en) 1972-07-24 1976-09-07 Kremers-Urban Company Compositions and methods therewith for penicillin hypersensitivity detection
LU72593A1 (en) 1975-05-28 1977-02-10
JPS5835520B2 (en) 1976-06-01 1983-08-03 株式会社第一ラジオアイソト−プ研究所 6-carboxymethylthiocortisol and its derivatives
US4152411A (en) 1977-07-27 1979-05-01 Akzona Incorporated High specific activity labeled substances
US4357259A (en) 1977-08-01 1982-11-02 Northwestern University Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres
US4847240A (en) 1978-01-16 1989-07-11 The Trustees Of Boston University Method of effecting cellular uptake of molecules
US4701521A (en) 1978-07-17 1987-10-20 The Trustees Of Boston University Method of effecting cellular uptake of molecules
US4279996A (en) 1978-10-09 1981-07-21 Seiwa Kasei Co., Ltd. Keratin hydrolyzate useful as hair fixatives
US4356166A (en) 1978-12-08 1982-10-26 University Of Utah Time-release chemical delivery system
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
DE2945100A1 (en) 1979-11-08 1981-05-21 Henkel KGaA, 4000 Düsseldorf INNOVATIVE SURFACES, THEIR PRODUCTION AND USE IN SKIN-FRIENDLY DETERGENTS, WASHING AND CLEANING AGENTS AND CONTAINER-SKIN-FRIENDLY, IN PARTICULAR COSMETIC PREPARATIONS
JPS56163456A (en) 1980-05-21 1981-12-16 Otsuka Pharmaceut Co Ltd Preparation of antigen
US4284537A (en) 1980-07-03 1981-08-18 The United States Of America As Represented By The Department Of Health And Human Services Conjugate of streptococcal M protein peptide vaccine
US4369037A (en) 1980-11-19 1983-01-18 Kao Soap Co., Ltd. Hair treatment cosmetics containing cationic keratin derivatives
US4631190A (en) 1981-06-26 1986-12-23 Shen Wei C Acidity-sensitive spacer molecule to control the release of pharmaceuticals from molecular carriers
DE3150878A1 (en) 1981-12-22 1983-06-30 Boehringer Mannheim Gmbh, 6800 Mannheim "METHOD AND REAGENT FOR DETERMINING CREATININ"
US4532207A (en) 1982-03-19 1985-07-30 G. D. Searle & Co. Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase
US4880911A (en) 1982-03-19 1989-11-14 G. D. Searle & Co. Fused polypeptides and methods for their detection
JP2519024B2 (en) 1982-06-07 1996-07-31 花王株式会社 Hair cosmetics
US4728639A (en) 1982-07-27 1988-03-01 University Of Tennessee Research Corporation Type-specific opsonic antibodies evoked with a synthetic peptide of streptococcal M protein conjugated to polylysine without adjuvant
US4521334A (en) 1982-07-27 1985-06-04 The University Of Tennesse Research Corporation Synthetic polypeptide fragments
US4597967A (en) 1982-07-27 1986-07-01 The University Of Tennessee Research Corp. Synthetic polypeptide fragments
US5258041A (en) 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
CA1249395A (en) 1982-09-30 1989-01-24 Tetsuya Tachikawa Human leukemia virus-related peptides, a process for production thereof, antibodies of the peptides and a process for production of the antibodies
FR2540380B1 (en) 1983-02-03 1986-02-07 Oreal COSMETIC COMPOSITION FOR PROTECTION AGAINST ULTRAVIOLET RADIATION AND ITS USE THEREFOR
EP0117469B2 (en) 1983-02-25 1996-09-04 Kao Corporation Hair cosmetics
JPS6043658A (en) 1983-08-19 1985-03-08 Fuji Photo Film Co Ltd Silver salt diffusion transfer method photographic image receiving element
MX9203290A (en) 1983-09-19 1992-08-01 Liposome Co Inc LOCALIZED SUPPLY USING FIBRONECTIN CONJUGATES.
LU85067A1 (en) 1983-10-28 1985-06-19 Oreal COMPOSITION AND METHOD FOR TREATING KERATINIC MATERIALS WITH AT LEAST ONE ANIONIC POLYMER AND AT LEAST ONE QUATERNIZED PROTEIN
US4671954A (en) 1983-12-13 1987-06-09 University Of Florida Microspheres for incorporation of therapeutic substances and methods of preparation thereof
US4534881A (en) 1983-12-19 1985-08-13 University Of South Alabama Inhibition of inorganic or biological CaCO3 deposition by poly amino acid derivatives
IT1180156B (en) 1984-01-09 1987-09-23 Crinos Industria Farmaco GLYCOPROTEIN-BASED COSMETIC COMPOSITION FOR SKIN TREATMENT
US4568559A (en) 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US4663286A (en) 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
US4749620A (en) 1984-02-15 1988-06-07 Massachusetts Institute Of Technology Encapsulated active material system
US4744933A (en) 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
US4695562A (en) 1984-04-06 1987-09-22 Univ. Of Tennessee Research Corp. Synthetic peptide compounds
FR2563431B1 (en) 1984-04-26 1987-03-06 Roussel Uclaf NEW COSMETIC COMPOSITIONS CONTAINING LYSED EXTRACTS FROM HAFNIA
US4834978A (en) 1984-10-01 1989-05-30 Biotek, Inc. Method of transdermal drug delivery
US5409904A (en) 1984-11-13 1995-04-25 Alcon Laboratories, Inc. Hyaluronic acid compositions and methods
DE3517205A1 (en) 1985-05-13 1986-11-13 Henkel KGaA, 4000 Düsseldorf OLIGOPEPTIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS SKIN-FRIENDLY SURFACTANTS
US5202431A (en) 1985-07-08 1993-04-13 Fidia, S.P.A. Partial esters of hyaluronic acid
US4645503A (en) 1985-08-27 1987-02-24 Orthomatrix Inc. Moldable bone-implant material
US4680338A (en) 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
SE8505921D0 (en) 1985-12-13 1985-12-13 Kabigen Ab A METHOD TO EXPORT GENE PRODUCTS TO THE GROWTH MEDIUM OF GRAM NEGATIVE BACTERIA
US5145675A (en) 1986-03-31 1992-09-08 Advanced Polymer Systems, Inc. Two step method for preparation of controlled release formulations
US5955109A (en) * 1985-12-18 1999-09-21 Advanced Polymer Systems, Inc. Methods and compositions for topical delivery of retinoic acid
CH667874A5 (en) 1985-12-19 1988-11-15 Battelle Memorial Institute BIODEGRADABLE SYNTHETIC POLYPEPTIDE AND ITS USE FOR THE PREPARATION OF MEDICAMENTS.
US4741872A (en) 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
GB8630720D0 (en) 1986-12-23 1987-02-04 Unilever Plc Cosmetic compositions
ATE76331T1 (en) 1987-02-25 1992-06-15 Hoechst Ag MICROENCAPSULATION OF BIOLOGICALLY ACTIVE MATERIAL.
JPH0665280B2 (en) * 1987-03-04 1994-08-24 味の素株式会社 Protein gelling agent and protein gelling method using the same
US5166320A (en) 1987-04-22 1992-11-24 University Of Connecticut Carrier system and method for the introduction of genes into mammalian cells
US5985354A (en) * 1995-06-07 1999-11-16 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
CA1323839C (en) 1987-05-11 1993-11-02 Loren Ralph Pickart Methods for stimulating hair growth
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US4924624A (en) 1987-10-22 1990-05-15 Temple University-Of The Commonwealth System Of Higher Education 2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof
US5510329A (en) 1988-04-26 1996-04-23 Ramot University For Applied Research And Industrial Development Ltd. Preparations for the treatment of eyes
US4879116A (en) 1988-06-13 1989-11-07 Charles Fox Skin protein complexing composition for the potentiation of the substantivity of aluminum acetate through the use of a cationic emulsifier as an aid in skin healing
US4908404A (en) 1988-08-22 1990-03-13 Biopolymers, Inc. Synthetic amino acid-and/or peptide-containing graft copolymers
US5840293A (en) * 1988-11-16 1998-11-24 Advanced Polymer Systems, Inc. Ionic beads for controlled release and adsorption
US5470829A (en) 1988-11-17 1995-11-28 Prisell; Per Pharmaceutical preparation
EP0406404B1 (en) 1989-01-20 1994-06-22 Diagnostica Stago Submicron particles, preparation and utilization in immunodiagnosis
US5098833A (en) 1989-02-23 1992-03-24 Genentech, Inc. DNA sequence encoding a functional domain of a lymphocyte homing receptor
US5354844A (en) 1989-03-16 1994-10-11 Boehringer Ingelheim International Gmbh Protein-polycation conjugates
FR2645741B1 (en) 1989-03-20 1995-06-23 Dior Christian Parfums PROCESS FOR FIXING A PRODUCT ON THE MEMBRANE OF A KERATINOCYTE BY MEANS OF A LIGAND-RECEPTOR BINDING, PROCESS FOR PREPARING SUCH A PRODUCT, PRODUCT OBTAINED, COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR PREPARING THE SAME
US5132230A (en) 1989-03-28 1992-07-21 Isolab, Inc. Primary standard and method of making secondary standards for calibration of glycated protein assays
US4973473A (en) 1989-06-23 1990-11-27 Revlon, Inc. Skin care preparation
US5091173A (en) 1989-06-29 1992-02-25 The University Of Dundee Hair growth composition
IT1230297B (en) 1989-07-05 1991-10-18 Carmelo Lo Duca SYRINGE USABLE ONLY ONCE.
FR2649888B1 (en) 1989-07-18 1994-08-26 Exsymol Sa PRODUCTS FOR SKIN APPLICATIONS, WITH COSMETIC OR / AND THERAPEUTIC EFFECTS
US5162505A (en) 1989-09-19 1992-11-10 Centocor Proteins modified with positively charged carriers and compositions prepared therefrom
US5461081A (en) 1989-09-28 1995-10-24 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
JP2571874B2 (en) * 1989-11-06 1997-01-16 アルカーメス コントロールド セラピューティクス，インコーポレイテッド Protein microsphere composition
US5271961A (en) 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
US5075019A (en) 1989-12-14 1991-12-24 Exxon Chemical Patents Inc. Low sediment method for preparing copper salts of polyolefinic-substituted dicarboxylic acids
US5733572A (en) * 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
DE4004430A1 (en) 1990-02-09 1991-08-14 Schering Ag CONSTRUCTED POLYALDEHYDE CONSTITUENTS
FR2658719B1 (en) 1990-02-28 1992-05-15 Oreal USE IN ASSOCIATION, IN THE PREPARATION OF COSMETIC COMPOSITIONS IN THE FORM OF COMPACTED POWDERS, HOLLOW MICROSPHERES OF THERMOPLASTIC SYNTHETIC MATERIAL, HEXAGONAL BORON NITRIDE, AND N-ACYL LYSINE.
IL97350A (en) 1990-03-09 1995-05-26 Ciba Geigy Hybridomas producing monoclonal antibodies specific for metolachlor such antibodies and their use in immunoassays for metolachlor
US5100956A (en) 1990-06-27 1992-03-31 Siltech Inc. Silicone protein polymers
US5149543A (en) 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
US5232984A (en) 1990-10-15 1993-08-03 The Board Of The Regents The University Of Texas Biocompatible microcapsules
US5646120A (en) * 1990-10-24 1997-07-08 Allelix Biopharmaceuticals, Inc. Peptide-based inhibitors of HIV replication
US5831001A (en) * 1990-10-24 1998-11-03 Allelix Biopharmaceuticals Inc. Treatment of herpesvirus infection
US5674849A (en) * 1990-10-24 1997-10-07 Allelix Biopharmaceuticals Inc. Anti-viral compositions
US5633230A (en) * 1990-10-24 1997-05-27 Allelix Biopharmaceuticals, Inc. Treatment of cytomegalovirus infection
KR920702912A (en) 1990-11-29 1992-12-17 후지이 야쓰오 Polymer Electrolyte Complex Antibacterial and Antimicrobial Materials
US5993805A (en) * 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
IT1247175B (en) 1991-04-19 1994-12-12 Fidia Spa PROCEDURE FOR PURIFICATION OF HYALURONIC ACID AND FRACTION OF PURE HYALURONIC ACID FOR OPHTHALMIC USE.
US5246780A (en) 1991-08-29 1993-09-21 L'oreal Coated particle for use in cosmetic preparations and method
US5521291A (en) 1991-09-30 1996-05-28 Boehringer Ingelheim International, Gmbh Conjugates for introducing nucleic acid into higher eucaryotic cells
US5487977A (en) 1991-10-01 1996-01-30 De Weck; Alain L. Method for the determination of sulfidoleukotrienes in tissues and biological fluids and its application in diagnosis of allergies and other inflammatory diseases
JPH07503943A (en) * 1991-10-29 1995-04-27 クローバー　コンソリデイテッド，リミテッド Cross-linked polysaccharides, polycations and lipids useful for encapsulation and drug release
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
US5578442A (en) 1992-03-23 1996-11-26 Vivorx, Inc. Graft copolymers of polycationic species and water-soluble polymers, and use therefor
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
US5614212A (en) * 1992-04-08 1997-03-25 International Medical Associates, Inc. Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
US5436291A (en) 1992-07-09 1995-07-25 University Of Michigan, The Board Of . . . Calcification-resistant synthetic biomaterials
FR2695558B1 (en) * 1992-09-11 1994-10-21 Oreal Cosmetic composition containing solid particles coated with an amphoteric polymer.
US5358706A (en) 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
EP0608117A3 (en) 1993-01-20 1996-01-17 Ono Pharmaceutical Co Antibodies for mevalonic acid and methods for determination of mevalonic acid.
AU6254494A (en) 1993-02-16 1994-09-14 Virginia Tech Intellectual Properties, Inc. Polyelectrolyte dna conjugation and genetic transformation of an animal
DE69310339T2 (en) * 1993-02-19 1997-08-21 Howard Green Preparations that contain corneocyte proteins
US5981719A (en) * 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5548064A (en) 1993-05-24 1996-08-20 Biotech Australia Pty Limited Vitamin B12 conjugates with EPO, analogues thereof and pharmaceutical compositions
FR2715847B1 (en) * 1994-02-08 1996-04-12 Rhone Poulenc Rorer Sa Composition containing nucleic acids, preparation and uses.
US5773577A (en) * 1994-03-03 1998-06-30 Protein Polymer Technologies Products comprising substrates capable of enzymatic cross-linking
US5505952A (en) 1994-04-19 1996-04-09 United States Surgical Corporation Modified synthetic cross-linked amino acid polymers and medical devices formed therefrom
EP0769063A1 (en) * 1994-06-27 1997-04-23 The Johns Hopkins University Targeted gene delivery system
US5716614A (en) * 1994-08-05 1998-02-10 Molecular/Structural Biotechnologies, Inc. Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-conjugated polycationic carrier
US5490980A (en) 1994-09-28 1996-02-13 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Covalent bonding of active agents to skin, hair or nails
FR2725369B1 (en) * 1994-10-07 1997-01-03 Oreal COSMETIC OR DERMATOLOGICAL COMPOSITION CONSISTING OF AN OIL IN WATER EMULSION BASED ON OIL CELLS PROVIDED WITH A LAMELLAR LIQUID CRYSTAL COATING
US5783178A (en) * 1994-11-18 1998-07-21 Supratek Pharma. Inc. Polymer linked biological agents
FR2728165A1 (en) * 1994-12-19 1996-06-21 Oreal USE OF AN ANTAGONIST OF SUBSTANCE P FOR THE TREATMENT OF SKIN REDNESS OF NEUROGENIC ORIGIN
FR2729946A1 (en) * 1995-01-31 1996-08-02 Oreal NOVEL LYSINE DERIVATIVES, PREPARATION METHOD, USES AND COMPOSITIONS COMPRISING SAME
US5629021A (en) * 1995-01-31 1997-05-13 Novavax, Inc. Micellar nanoparticles
US5916790A (en) * 1995-03-03 1999-06-29 Metabolex, Inc. Encapsulation compositions, and methods
US5587301A (en) 1995-03-10 1996-12-24 Incyte Pharmaceuticals, Inc. DNA encoding a hyaluronan receptor expressed in human umbilical vein endothelial cells
US5686113A (en) * 1995-03-21 1997-11-11 Temple University Of The Commonwealth System Of Higher Education Microcapsules of predetermined peptide(s) specificity (ies), their preparation and uses
FR2732220B1 (en) * 1995-03-28 1997-04-25 Oreal USE OF A CGRP ANTAGONIST TO TREAT LICHENS AND PRURITES AND COMPOSITION OBTAINED
US5811510A (en) * 1995-04-14 1998-09-22 General Hospital Corporation Biodegradable polyacetal polymers and methods for their formation and use
FR2736042B1 (en) * 1995-06-30 1997-09-12 Rhone Poulenc Chimie COLLOIDAL DISPERSION AND REDISPERSIBLE COMPOSITION IN THE FORM OF A COLLOIDAL DISPERSION BASED ON CERIUM OXIDE
US5968543A (en) * 1996-01-05 1999-10-19 Advanced Polymer Systems, Inc. Polymers with controlled physical state and bioerodibility
US5785977A (en) * 1996-02-07 1998-07-28 Breithbarth; Richard Non-metallic microparticle carrier materials
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5913884A (en) * 1996-09-19 1999-06-22 The General Hospital Corporation Inhibition of fibrosis by photodynamic therapy
DE69818987T2 (en) * 1997-05-21 2004-07-29 The Board Of Trustees Of The Leland Stanford Junior University, Stanford COMPOSITION AND METHOD FOR DELAYING THE TRANSPORT BY BIOLOGICAL MEMBRANES
US5861149A (en) * 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
CN100335624C (en) * 1997-06-25 2007-09-05 诺沃奇梅兹有限公司 Modified polypeptide
US6045835A (en) * 1997-10-08 2000-04-04 Givaudan Roure (International) Sa Method of encapsulating flavors and fragrances by controlled water transport into microcapsules
US6958148B1 (en) * 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
US6919076B1 (en) * 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
JP3981525B2 (en) * 1998-01-20 2007-09-26 ハワード・グリーン Transglutaminase linkage of substances to tissues
US5962018A (en) * 1998-04-28 1999-10-05 Avon Products, Inc. Method of treating the skin with organic acids in anhydrous microsphere delivery systems
US5939453A (en) * 1998-06-04 1999-08-17 Advanced Polymer Systems, Inc. PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
WO2001007009A1 (en) * 1999-07-22 2001-02-01 Pericor Science, Inc. Lysine oxidase linkage of agents to tissue

Also Published As

Publication number Publication date
WO2002007707A2 (en) 2002-01-31
WO2002007707A3 (en) 2002-08-15
US20060110379A1 (en) 2006-05-25
JP2004504340A (en) 2004-02-12
CA2415345A1 (en) 2002-01-31
US6958148B1 (en) 2005-10-25
EP1303260A2 (en) 2003-04-23

Similar Documents

Publication Publication Date Title
AU2002224524A1 (en) Linkage of agents using microparticles
AU2001252135A1 (en) Therapeutic agents
AU2002338914A1 (en) Cosmetic agents
AU2002243277A1 (en) Methods and compositions for encapsulating active agents
AU2001290779A1 (en) Shampoo and body wash composition
AU2001291222A1 (en) Wax-modified thermosettable compositions
AU2001291183A1 (en) Long acting antidepressant microparticles
AU2001294073A1 (en) Processor architecture
AU2001295768A1 (en) Processor architecture
AU2002221601A1 (en) Disinfectant
AU2002214284A1 (en) Anti-helicobacterial agents
AU2001281666A1 (en) Lavatory
AU2001259657A1 (en) Software modem architecture
AU2001272974A1 (en) Human receptors
AU2364601A (en) Detergent compositions comprising benefit agents
AU2001283586A1 (en) Enhancement of the action of anti-infective agents
AU2451500A (en) Therapeutic agents
AU2001240605A1 (en) Endoparasiticidal agents
AU2001241771A1 (en) Use of avocado-soybean unsaponifiable preparations
AU2002239291A1 (en) G protein coupled receptors
AU2001273903A1 (en) Therapeutic agents
AU2002241767A1 (en) Concurrent-multitasking processor
AU5973600A (en) Therapeutic agents
AU2001252713A1 (en) Pesticide composition
AU2001274683A1 (en) Contrast agents