JP2004502441A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004502441A5 JP2004502441A5 JP2002508311A JP2002508311A JP2004502441A5 JP 2004502441 A5 JP2004502441 A5 JP 2004502441A5 JP 2002508311 A JP2002508311 A JP 2002508311A JP 2002508311 A JP2002508311 A JP 2002508311A JP 2004502441 A5 JP2004502441 A5 JP 2004502441A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- oligonucleotides
- oligonucleotide
- microarray
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 25
- 108091034117 Oligonucleotide Proteins 0.000 claims 12
- 108090000623 proteins and genes Proteins 0.000 claims 10
- 108091033319 polynucleotide Proteins 0.000 claims 7
- 239000002157 polynucleotide Substances 0.000 claims 7
- 102000040430 polynucleotide Human genes 0.000 claims 7
- 239000000523 sample Substances 0.000 claims 7
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 6
- 238000002493 microarray Methods 0.000 claims 5
- 239000003550 marker Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 238000011534 incubation Methods 0.000 claims 3
- 108010058532 UTP-hexose-1-phosphate uridylyltransferase Proteins 0.000 claims 2
- 102000006321 UTP-hexose-1-phosphate uridylyltransferase Human genes 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 238000003752 polymerase chain reaction Methods 0.000 claims 2
- 108700028369 Alleles Proteins 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 102100021519 Hemoglobin subunit beta Human genes 0.000 claims 1
- 108091005904 Hemoglobin subunit beta Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 238000003205 genotyping method Methods 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/613,006 US6913879B1 (en) | 2000-07-10 | 2000-07-10 | Microarray method of genotyping multiple samples at multiple LOCI |
| PCT/US2001/021163 WO2002003849A2 (en) | 2000-07-10 | 2001-07-03 | Microarray method of genotyping multiple samples at multiple loci |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004502441A JP2004502441A (ja) | 2004-01-29 |
| JP2004502441A5 true JP2004502441A5 (enExample) | 2005-04-14 |
| JP4175884B2 JP4175884B2 (ja) | 2008-11-05 |
Family
ID=24455485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002508311A Expired - Fee Related JP4175884B2 (ja) | 2000-07-10 | 2001-07-03 | 複数の遺伝子座で複数のサンプルを遺伝子タイピングするマイクロアレイ方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6913879B1 (enExample) |
| EP (1) | EP1343911B1 (enExample) |
| JP (1) | JP4175884B2 (enExample) |
| KR (1) | KR100756015B1 (enExample) |
| CN (1) | CN100520401C (enExample) |
| AT (1) | ATE363543T1 (enExample) |
| AU (2) | AU1874002A (enExample) |
| CA (1) | CA2414105C (enExample) |
| DE (1) | DE60128720T2 (enExample) |
| IL (2) | IL153848A0 (enExample) |
| IS (1) | IS2651B (enExample) |
| NO (1) | NO20030101L (enExample) |
| NZ (1) | NZ523560A (enExample) |
| RU (1) | RU2003103771A (enExample) |
| TW (1) | TWI280282B (enExample) |
| WO (1) | WO2002003849A2 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10000001A1 (de) * | 2000-01-01 | 2001-07-19 | Agrobiogen Gmbh | DNA-Matrizes und deren Verwendung zur Untersuchung von Individuen einer Population |
| US6913879B1 (en) * | 2000-07-10 | 2005-07-05 | Telechem International Inc. | Microarray method of genotyping multiple samples at multiple LOCI |
| GB0208364D0 (en) * | 2002-04-11 | 2002-05-22 | Sec Dep For The Home Departmen | Improvements in and relating to methods and apparatus for genotyping |
| WO2004044242A1 (en) * | 2002-11-14 | 2004-05-27 | John Nicholas Housby | Polymorphism assay |
| US7097070B2 (en) | 2003-08-15 | 2006-08-29 | Protedyne Corporation | Method and apparatus for handling small volume fluid samples |
| JP4458327B2 (ja) * | 2003-08-28 | 2010-04-28 | キヤノン株式会社 | 標的物質の定量方法および該方法に用いるプローブ担体 |
| US7108979B2 (en) * | 2003-09-03 | 2006-09-19 | Agilent Technologies, Inc. | Methods to detect cross-contamination between samples contacted with a multi-array substrate |
| US20080220420A1 (en) * | 2004-11-19 | 2008-09-11 | Shimadzu Corporation | Method of Detecting Gene Polymorphism, Method of Diagnosing, Apparatus Therefor, and Test Reagent Kit |
| RU2348695C2 (ru) | 2006-05-23 | 2009-03-10 | Закрытое акционерное общество "Молекулярно-медицинские технологии" | Дифференцирующий и специфический олигонуклеотиды для идентификации последовательностей днк инфекционных агентов в биологических материалах, способ видовой идентификации инфекционных агентов, биочип и набор для осуществления этого способа |
| GB0618514D0 (en) * | 2006-09-20 | 2006-11-01 | Univ Nottingham Trent | Method of detecting interactions on a microarray using nuclear magnetic resonance |
| EP2099935B1 (en) * | 2006-11-30 | 2014-02-26 | The Regents Of The University Of California | Array for detecting microbes |
| CN101801992A (zh) * | 2007-05-31 | 2010-08-11 | 孟山都技术公司 | 大豆多态性与基因分型方法 |
| CL2008002553A1 (es) | 2007-08-29 | 2009-09-04 | Monsanto Technology Llc | Metodo de mejoramiento de plantas mediante la introduccion de loci de caracteristicas cuantitativas asociadas con resistencia a la mancha foliar gris. |
| EP2604704B1 (en) | 2008-02-01 | 2018-10-03 | The General Hospital Corporation | Use of microvesicles in diagnosis and prognosis of brain tumor |
| US20110195426A1 (en) | 2009-07-16 | 2011-08-11 | The General Hospital Corporation | Nucleic acids analysis |
| CN102098909B (zh) | 2008-04-24 | 2014-12-31 | 孟山都技术有限公司 | 鉴定大豆中亚洲大豆锈病抗性数量性状基因座的方法和其组合物 |
| US9393566B2 (en) * | 2008-06-23 | 2016-07-19 | Canon U.S. Life Sciences, Inc. | System and method for temperature referencing for melt curve data collection |
| US12129514B2 (en) | 2009-04-30 | 2024-10-29 | Molecular Loop Biosolutions, Llc | Methods and compositions for evaluating genetic markers |
| JP2012525147A (ja) | 2009-04-30 | 2012-10-22 | グッド スタート ジェネティクス， インコーポレイテッド | 遺伝マーカーを評価するための方法および組成物 |
| US20100299773A1 (en) * | 2009-05-20 | 2010-11-25 | Monsanto Technology Llc | Methods and compositions for selecting an improved plant |
| EP2475989A4 (en) | 2009-09-09 | 2013-02-27 | Gen Hospital Corp | USE OF MICROVESICLES IN THE ANALYSIS OF KRAS MUTATIONS |
| EP3461912B1 (en) | 2009-09-09 | 2022-07-13 | The General Hospital Corporation | Use of microvesicles in analyzing nucleic acid profiles |
| US20140045915A1 (en) | 2010-08-31 | 2014-02-13 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| EP2638057B1 (en) | 2010-11-10 | 2019-03-06 | Exosome Diagnostics, Inc. | Method for isolation of nucleic acid containing particles and extraction of nucleic acids therefrom |
| US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
| WO2012149193A2 (en) | 2011-04-29 | 2012-11-01 | Monsanto Technology Llc | Diagnostic molecular markers for seed lot purity traits in soybeans |
| EP3569607A1 (en) | 2011-05-11 | 2019-11-20 | Exosome Diagnostics, Inc. | Nucleic acid extraction from heterogeneous biological materials |
| EP2748335B1 (en) | 2011-08-22 | 2018-10-03 | Exosome Diagnostics, Inc. | Urine biomarkers |
| WO2013033611A1 (en) | 2011-08-31 | 2013-03-07 | Monsanto Technology Llc | Methods and compositions for watermelon firmness |
| CA2852665A1 (en) | 2011-10-17 | 2013-04-25 | Good Start Genetics, Inc. | Analysis methods |
| US10174361B2 (en) | 2011-11-10 | 2019-01-08 | Exosome Diagnostics, Inc. | Cerebrospinal fluid assay |
| WO2013106737A1 (en) * | 2012-01-13 | 2013-07-18 | Data2Bio | Genotyping by next-generation sequencing |
| US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
| US8812422B2 (en) | 2012-04-09 | 2014-08-19 | Good Start Genetics, Inc. | Variant database |
| US10227635B2 (en) | 2012-04-16 | 2019-03-12 | Molecular Loop Biosolutions, Llc | Capture reactions |
| CN104995311A (zh) | 2012-08-30 | 2015-10-21 | 外来体诊断公司 | 用于核酸测定的对照 |
| CN105025878A (zh) | 2012-10-03 | 2015-11-04 | 外来体诊断公司 | 微泡在医学疾病和病况的诊断、预后和治疗中的用途 |
| CA2890441A1 (en) | 2012-11-07 | 2014-05-15 | Good Start Genetics, Inc. | Methods and systems for identifying contamination in samples |
| GB201220924D0 (en) | 2012-11-21 | 2013-01-02 | Cancer Res Inst Royal | Materials and methods for determining susceptibility or predisposition to cancer |
| ES2689084T3 (es) * | 2012-12-03 | 2018-11-08 | Statens Serum Institut | Método de diagnóstico de la galactosemia en un cribado neonatal |
| US10314253B2 (en) | 2012-12-04 | 2019-06-11 | Seminis Vegetable Seeds, Inc. | Methods and compositions for watermelon sex expression |
| WO2014152421A1 (en) | 2013-03-14 | 2014-09-25 | Good Start Genetics, Inc. | Methods for analyzing nucleic acids |
| US10294489B2 (en) | 2013-03-15 | 2019-05-21 | Board Of Trustees Of Southern Illinois University | Soybean resistant to cyst nematodes |
| WO2014197377A2 (en) | 2013-06-03 | 2014-12-11 | Good Start Genetics, Inc. | Methods and systems for storing sequence read data |
| US10059999B2 (en) | 2013-06-10 | 2018-08-28 | Monsanto Technology Llc | Molecular markers associated with soybean tolerance to low iron growth conditions |
| US10301681B2 (en) | 2013-08-06 | 2019-05-28 | Exosome Diagnostics, Inc. | Methods of treating a subject with a high gleason score prostate cancer |
| NZ630628A (en) | 2013-10-08 | 2015-04-24 | Seminis Vegetable Seeds Inc | Methods and compositions for peronospora resistance in spinach |
| EP3058096A1 (en) | 2013-10-18 | 2016-08-24 | Good Start Genetics, Inc. | Methods for assessing a genomic region of a subject |
| US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
| NZ630717A (en) | 2013-11-27 | 2016-04-29 | Seminis Vegetable Seeds Inc | Disease resistance loci in onion |
| EA202091497A3 (ru) | 2014-02-21 | 2020-12-30 | Зингента Партисипейшнс Аг | Генетические локусы, связанные с повышенной фертильностью у маиса |
| NZ630710A (en) | 2014-02-27 | 2016-03-31 | Seminis Vegetable Seeds Inc | Compositions and methods for peronospora resistance in spinach |
| US11053548B2 (en) | 2014-05-12 | 2021-07-06 | Good Start Genetics, Inc. | Methods for detecting aneuploidy |
| US10316369B2 (en) | 2014-06-27 | 2019-06-11 | Seminis Vegetable Seeds, Inc. | Methods and assays for male sterile watermelon |
| US20160048608A1 (en) | 2014-08-15 | 2016-02-18 | Good Start Genetics, Inc. | Systems and methods for genetic analysis |
| WO2016040446A1 (en) | 2014-09-10 | 2016-03-17 | Good Start Genetics, Inc. | Methods for selectively suppressing non-target sequences |
| CA2999708A1 (en) | 2014-09-24 | 2016-03-31 | Good Start Genetics, Inc. | Process control for increased robustness of genetic assays |
| EP3005862A1 (en) | 2014-10-10 | 2016-04-13 | Seminis Vegetable Seeds, Inc. | Melon plants with improved disease tolerance |
| US10066259B2 (en) | 2015-01-06 | 2018-09-04 | Good Start Genetics, Inc. | Screening for structural variants |
| HUE053541T2 (hu) | 2015-04-28 | 2021-07-28 | Monsanto Technology Llc | Eljárások és készítmények brachitikus kukoricanövények elõállítására |
| CA2981819A1 (en) | 2015-04-30 | 2016-11-03 | Monsanto Technology Llc | Methods for producing canola plants with clubroot resistance and compositions thereof |
| WO2017031059A1 (en) | 2015-08-18 | 2017-02-23 | Monsanto Technology Llc | Methods for producing cotton plants with enhanced drought tolerance and compositions thereof |
| US10448595B2 (en) | 2015-09-03 | 2019-10-22 | Seminis Vegetable Seeds, Inc. | Downy mildew resistant lettuce plants |
| US10858709B2 (en) | 2015-09-10 | 2020-12-08 | Monsanto Technology Llc | Methods for producing corn plants with downy mildew resistance and compositions thereof |
| BR112018012039A2 (pt) | 2015-12-18 | 2018-12-04 | Monsanto Technology Llc | métodos para produção de plantas de milho com resistência à helmintosporiose e composições dos mesmos |
| KR20190020649A (ko) | 2016-04-15 | 2019-03-04 | 엑소좀 디아그노스틱스, 인크. | 역형성 림프종 키나아제(alk) 핵산 및 alk 융합 전사물의 혈장 기반 검출 및 암의 진단 및 치료에 있어 이의 용도 |
| WO2017197399A1 (en) | 2016-05-13 | 2017-11-16 | Exosome Diagnostics, Inc. | Automated and manual methods for isolation of extracellular vesicles and co-isolation of cell-free dna from biofluids |
| EP3496528A4 (en) | 2016-08-11 | 2020-03-18 | Monsanto Technology LLC | METHODS AND COMPOSITIONS FOR PRODUCING CORN PLANTS WITH RESISTANCE TO LATE FAILURE |
| AU2017232187B2 (en) | 2016-09-30 | 2023-11-09 | Seminis Vegetable Seeds, Inc. | Xanthomonas resistant brassica oleracea plants |
| CN110191962A (zh) | 2016-10-21 | 2019-08-30 | 外来体诊断公司 | 外来体相关核酸的测序和分析 |
| AU2017366813B2 (en) | 2016-11-30 | 2023-04-20 | Exosome Diagnostics, Inc. | Methods and compositions to detect mutations in plasma using exosomal RNA and cell free DNA from non-small cell lung cancer patients |
| WO2018126278A2 (en) | 2017-01-02 | 2018-07-05 | Exosome Diagnostics, Inc. | Methods to distinguish rna and dna in a combined preparation |
| EP3652315A4 (en) | 2017-07-12 | 2021-09-01 | Exosome Diagnostics, Inc. | METHODS FOR ISOLATION AND ENRICHMENT OF EXTRACELLULAR VESICLE POPULATIONS DERIVED FROM BIOFLUIDS, AND ASSOCIATED METHODS OF USE |
| US11268102B2 (en) | 2018-05-16 | 2022-03-08 | University Of Florida Research Foundation, Incorporated | Compositions and methods for identifying and selecting brachytic locus in solanaceae |
| WO2020106853A1 (en) | 2018-11-20 | 2020-05-28 | Exosome Diagnostics, Inc. | Compositions and methods for internal controls of microvesicle isolations |
| CA3145881A1 (en) | 2019-01-15 | 2020-07-23 | Seminis Vegetable Seeds, Inc. | Green bean plants with improved resistance to sclerotinia sclerotiorum and genetic markers therefor |
| US11542513B2 (en) | 2019-09-26 | 2023-01-03 | Seminis Vegetable Seeds, Inc. | Lettuce plants having resistance to Nasonovia ribisnigri biotype Nr:1 |
| AU2021204717A1 (en) | 2020-07-15 | 2022-02-03 | Seminis Vegetable Seeds, Inc. | Green Bean Plants with Improved Disease Resistance |
| US20230193310A1 (en) | 2021-12-10 | 2023-06-22 | Seminis Vegetabe Seeds, Inc. | Lettuce plants having resistance to downy mildew |
| US20230404003A1 (en) | 2022-06-21 | 2023-12-21 | Seminis Vegetable Seeds, Inc. | Novel qtls conferring resistance to cucumber mosaic virus |
| US20240344079A1 (en) | 2023-04-14 | 2024-10-17 | Seminis Vegetable Seeds, Inc. | Methods and compositions for peronospora resistance in spinach |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981783A (en) | 1986-04-16 | 1991-01-01 | Montefiore Medical Center | Method for detecting pathological conditions |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5700637A (en) | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
| US5800992A (en) * | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5925525A (en) | 1989-06-07 | 1999-07-20 | Affymetrix, Inc. | Method of identifying nucleotide differences |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| WO1993021345A1 (en) | 1992-04-21 | 1993-10-28 | The Regents Of The University Of California | Multicolor in situ hybridization methods for genetic testing |
| US5403708A (en) | 1992-07-06 | 1995-04-04 | Brennan; Thomas M. | Methods and compositions for determining the sequence of nucleic acids |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US6045996A (en) | 1993-10-26 | 2000-04-04 | Affymetrix, Inc. | Hybridization assays on oligonucleotide arrays |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5834181A (en) | 1994-07-28 | 1998-11-10 | Genzyme Corporation | High throughput screening method for sequences or genetic alterations in nucleic acids |
| US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| US5958342A (en) | 1996-05-17 | 1999-09-28 | Incyte Pharmaceuticals, Inc. | Jet droplet device |
| AU3568897A (en) | 1996-06-07 | 1998-01-05 | Eos Biotechnology, Inc. | Immobilised linear oligonucleotide arrays |
| US5919626A (en) | 1997-06-06 | 1999-07-06 | Orchid Bio Computer, Inc. | Attachment of unmodified nucleic acids to silanized solid phase surfaces |
| US6013449A (en) | 1997-11-26 | 2000-01-11 | The United States Of America As Represented By The Department Of Health And Human Services | Probe-based analysis of heterozygous mutations using two-color labelling |
| US6232066B1 (en) | 1997-12-19 | 2001-05-15 | Neogen, Inc. | High throughput assay system |
| US6238869B1 (en) | 1997-12-19 | 2001-05-29 | High Throughput Genomics, Inc. | High throughput assay system |
| CA2306446A1 (en) | 1998-09-25 | 2000-04-06 | Massachusetts Institute Of Technology | Methods and products related to genotyping and dna analysis |
| US6268147B1 (en) * | 1998-11-02 | 2001-07-31 | Kenneth Loren Beattie | Nucleic acid analysis using sequence-targeted tandem hybridization |
| WO2001061043A2 (en) * | 2000-02-16 | 2001-08-23 | Illumina, Inc. | Parallel genotyping of multiple patient samples |
| US6913879B1 (en) * | 2000-07-10 | 2005-07-05 | Telechem International Inc. | Microarray method of genotyping multiple samples at multiple LOCI |
-
2000
- 2000-07-10 US US09/613,006 patent/US6913879B1/en not_active Expired - Fee Related
-
2001
- 2001-07-03 AU AU1874002A patent/AU1874002A/xx active Pending
- 2001-07-03 KR KR1020037000360A patent/KR100756015B1/ko not_active Expired - Fee Related
- 2001-07-03 NZ NZ523560A patent/NZ523560A/en unknown
- 2001-07-03 RU RU2003103771/13A patent/RU2003103771A/ru not_active Application Discontinuation
- 2001-07-03 IL IL15384801A patent/IL153848A0/xx unknown
- 2001-07-03 JP JP2002508311A patent/JP4175884B2/ja not_active Expired - Fee Related
- 2001-07-03 AT AT01984136T patent/ATE363543T1/de not_active IP Right Cessation
- 2001-07-03 AU AU2002218740A patent/AU2002218740B2/en not_active Ceased
- 2001-07-03 CN CNB018139728A patent/CN100520401C/zh not_active Expired - Fee Related
- 2001-07-03 WO PCT/US2001/021163 patent/WO2002003849A2/en not_active Ceased
- 2001-07-03 EP EP01984136A patent/EP1343911B1/en not_active Expired - Lifetime
- 2001-07-03 DE DE60128720T patent/DE60128720T2/de not_active Expired - Lifetime
- 2001-07-03 CA CA2414105A patent/CA2414105C/en not_active Expired - Fee Related
- 2001-07-09 TW TW090116726A patent/TWI280282B/zh not_active IP Right Cessation
-
2003
- 2003-01-08 IL IL153848A patent/IL153848A/en not_active IP Right Cessation
- 2003-01-09 IS IS6674A patent/IS2651B/is unknown
- 2003-01-09 NO NO20030101A patent/NO20030101L/no not_active Application Discontinuation
-
2004
- 2004-11-05 US US10/981,829 patent/US20050153318A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004502441A5 (enExample) | ||
| US10760123B2 (en) | Sequential sequencing | |
| US6306643B1 (en) | Methods of using an array of pooled probes in genetic analysis | |
| US6027880A (en) | Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis | |
| US20040096853A1 (en) | Isothermal amplification of nucleic acids on a solid support | |
| JP2004531274A5 (enExample) | ||
| US6221635B1 (en) | Methods for solid-phase amplification of DNA template (SPADT) using multiarrays | |
| CA2374406A1 (en) | Microarray-based analysis of polynucleotide sequence variations | |
| CA2414105A1 (en) | Microarray method of genotyping multiple samples at multiple loci | |
| JPH08510910A (ja) | ヒトゲノムの延長ヌクレオチド反復配列の直接検出 | |
| WO2000047766A1 (en) | Method for detecting variant nucleotides using arms multiplex amplification | |
| WO2000047767A1 (en) | Oligonucleotide array and methods of use | |
| JP2002525127A5 (enExample) | ||
| Kwok et al. | Single‐molecule analysis for molecular haplotyping | |
| JP2007530026A (ja) | 核酸配列決定 | |
| CN108291254B (zh) | 用于检测单核苷酸多态性的试剂盒和方法 | |
| EP1620536A4 (en) | MOLECULAR HAPLOTPIZATION OF GENOMIC DNA | |
| Pastinen | Single nucleotide polymorphism genotyping using microarrays | |
| Brès et al. | New method for DNA microarrays development: applied to human platelet antigens polymorphisms | |
| JP4283578B2 (ja) | 不一致増幅物質を含むプローブ核酸を用いる標的配列の検出方法、プローブ核酸および標的配列検出用アッセイキット | |
| CA2393874C (en) | Method for selectively isolating a nucleic acid | |
| US20240167088A1 (en) | Methods and devices of generating clusters of amplicons | |
| JP5530185B2 (ja) | 核酸検出方法及び核酸検出用キット | |
| JP2005245272A (ja) | アルコール脱水素酵素遺伝子多型の簡易検出方法および検出用試薬 | |
| Pastinen | Single Nucleotide |