JP2004501727A5 - - Google Patents
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- Publication number
- JP2004501727A5 JP2004501727A5 JP2002506803A JP2002506803A JP2004501727A5 JP 2004501727 A5 JP2004501727 A5 JP 2004501727A5 JP 2002506803 A JP2002506803 A JP 2002506803A JP 2002506803 A JP2002506803 A JP 2002506803A JP 2004501727 A5 JP2004501727 A5 JP 2004501727A5
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- reservoir
- reservoir electrode
- patient
- polymer material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000463 material Substances 0.000 claims 15
- 239000002861 polymer material Substances 0.000 claims 14
- 150000003839 salts Chemical class 0.000 claims 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 6
- 239000000654 additive Substances 0.000 claims 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 6
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 5
- 230000002745 absorbent Effects 0.000 claims 5
- 239000002250 absorbent Substances 0.000 claims 5
- 230000000996 additive effect Effects 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 4
- YLXIPWWIOISBDD-NDAAPVSOSA-N (2r,3r)-2,3-dihydroxybutanedioic acid;4-[(1r)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.CNC[C@H](O)C1=CC=C(O)C(O)=C1 YLXIPWWIOISBDD-NDAAPVSOSA-N 0.000 claims 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims 3
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 3
- 229910001514 alkali metal chloride Inorganic materials 0.000 claims 3
- 125000005907 alkyl ester group Chemical group 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 150000003841 chloride salts Chemical class 0.000 claims 3
- 235000011187 glycerol Nutrition 0.000 claims 3
- 150000002500 ions Chemical class 0.000 claims 3
- YECIFGHRMFEPJK-UHFFFAOYSA-N lidocaine hydrochloride monohydrate Chemical compound O.[Cl-].CC[NH+](CC)CC(=O)NC1=C(C)C=CC=C1C YECIFGHRMFEPJK-UHFFFAOYSA-N 0.000 claims 3
- 229960005323 phenoxyethanol Drugs 0.000 claims 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims 2
- 229910021607 Silver chloride Inorganic materials 0.000 claims 2
- 239000012736 aqueous medium Substances 0.000 claims 2
- 239000002585 base Substances 0.000 claims 2
- 229960004106 citric acid Drugs 0.000 claims 2
- 239000012458 free base Substances 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 229910001507 metal halide Inorganic materials 0.000 claims 2
- 150000005309 metal halides Chemical class 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000010409 thin film Substances 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 229910001508 alkali metal halide Inorganic materials 0.000 claims 1
- 150000008045 alkali metal halides Chemical class 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 238000005260 corrosion Methods 0.000 claims 1
- 230000007797 corrosion Effects 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 239000011243 crosslinked material Substances 0.000 claims 1
- WBZKQQHYRPRKNJ-UHFFFAOYSA-L disulfite Chemical compound [O-]S(=O)S([O-])(=O)=O WBZKQQHYRPRKNJ-UHFFFAOYSA-L 0.000 claims 1
- 238000012377 drug delivery Methods 0.000 claims 1
- 229960005150 glycerol Drugs 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 229960004393 lidocaine hydrochloride Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940045641 monobasic sodium phosphate Drugs 0.000 claims 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims 1
- 235000019799 monosodium phosphate Nutrition 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 claims 1
- 229940001584 sodium metabisulfite Drugs 0.000 claims 1
- 235000010262 sodium metabisulphite Nutrition 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/610,563 US6629968B1 (en) | 2000-06-30 | 2000-06-30 | Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode |
| PCT/US2001/020886 WO2002002182A2 (en) | 2000-06-30 | 2001-06-29 | Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004501727A JP2004501727A (ja) | 2004-01-22 |
| JP2004501727A5 true JP2004501727A5 (https=) | 2005-06-09 |
| JP4024673B2 JP4024673B2 (ja) | 2007-12-19 |
Family
ID=24445534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002506803A Expired - Fee Related JP4024673B2 (ja) | 2000-06-30 | 2001-06-29 | 保存安定性を有するイオントフォレシス用リザーバ電極及び該リザーバ電極を具えるイオントフォレシスシステム |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6629968B1 (https=) |
| EP (1) | EP1294439B1 (https=) |
| JP (1) | JP4024673B2 (https=) |
| AT (1) | ATE369891T1 (https=) |
| AU (1) | AU2001273104A1 (https=) |
| CA (1) | CA2413624C (https=) |
| DE (1) | DE60129965T2 (https=) |
| WO (1) | WO2002002182A2 (https=) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6757560B1 (en) * | 1999-04-09 | 2004-06-29 | Novosis Pharma Ag | Transdermal delivery system (TDS) with electrode network |
| JP4033382B2 (ja) * | 2002-04-08 | 2008-01-16 | 久光製薬株式会社 | インスリン投与装置 |
| AU2003218271A1 (en) | 2002-04-18 | 2003-11-03 | Carnegie Mellon University | Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids |
| US7776600B2 (en) | 2002-04-18 | 2010-08-17 | Carnegie Mellon University | Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids |
| JP4089875B2 (ja) * | 2002-06-12 | 2008-05-28 | 共同印刷株式会社 | 凹部を含む電極装置 |
| US7917205B2 (en) * | 2003-03-20 | 2011-03-29 | Nobuyoshi Karashima | Iontophoresis-based medical device |
| JP3493359B1 (ja) * | 2003-03-20 | 2004-02-03 | 宣美 辛島 | イオン泳動式治療装置 |
| ATE424884T1 (de) * | 2003-03-31 | 2009-03-15 | Alza Corp | Elektrotransportvorrichtung mit einem behältergehäuse mit einem biegsamen leitfähigen element |
| WO2005020967A1 (ja) * | 2003-08-29 | 2005-03-10 | Hisamitsu Pharmaceutical Co., Inc. | 電気的薬物移送製剤 |
| CA2553901C (en) | 2004-01-22 | 2015-01-20 | Rehabtronics Inc. | Method of routing electrical current to bodily tissues via implanted passive conductors |
| US20100016929A1 (en) * | 2004-01-22 | 2010-01-21 | Arthur Prochazka | Method and system for controlled nerve ablation |
| US20050234516A1 (en) * | 2004-02-16 | 2005-10-20 | Gueret Jean-Louis H | Treatment kit, composite structure, electric exciter, and cosmetic treatment method |
| FR2866240B1 (fr) * | 2004-02-16 | 2006-06-23 | Oreal | Kit de traitement comportant une structure composite a appliquer sur la peau et un excitateur electrique |
| US20050228335A1 (en) * | 2004-04-07 | 2005-10-13 | Reddy Vilambi N | Physical, structural, mechanical, electrical and electromechanical features for use in association with electrically assisted delivery devices and systems |
| US20050228336A1 (en) * | 2004-04-07 | 2005-10-13 | Preston Keusch | Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability |
| US7537590B2 (en) * | 2004-07-30 | 2009-05-26 | Microchips, Inc. | Multi-reservoir device for transdermal drug delivery and sensing |
| JP4728631B2 (ja) * | 2004-11-30 | 2011-07-20 | Ｔｔｉ・エルビュー株式会社 | イオントフォレーシス装置 |
| US7590444B2 (en) * | 2004-12-09 | 2009-09-15 | Tti Ellebeau, Inc. | Iontophoresis device |
| JP4731931B2 (ja) * | 2005-02-03 | 2011-07-27 | Ｔｔｉ・エルビュー株式会社 | イオントフォレーシス装置 |
| JP4793806B2 (ja) * | 2005-03-22 | 2011-10-12 | Ｔｔｉ・エルビュー株式会社 | イオントフォレーシス装置 |
| US8386029B2 (en) | 2005-03-31 | 2013-02-26 | Encore Medical Asset Corporation | Apparatus for electrotherapy drug delivery with added impurities |
| US20070027426A1 (en) * | 2005-06-24 | 2007-02-01 | Transcutaneous Technologies Inc. | Iontophoresis device to deliver active agents to biological interfaces |
| US8386030B2 (en) | 2005-08-08 | 2013-02-26 | Tti Ellebeau, Inc. | Iontophoresis device |
| US8295922B2 (en) | 2005-08-08 | 2012-10-23 | Tti Ellebeau, Inc. | Iontophoresis device |
| US20070088331A1 (en) * | 2005-08-18 | 2007-04-19 | Transcutaneous Technologies Inc. | Method and apparatus for managing active agent usage, and active agent injecting device |
| EP1925336A4 (en) | 2005-09-15 | 2011-01-19 | Tti Ellebeau Inc | ROD TYPE IONTOPHORESIS APPARATUS |
| US20070078434A1 (en) * | 2005-09-30 | 2007-04-05 | Vyteris, Inc. | Indications For Local Transport of Anaesthetic Agents By Electrotransport Devices |
| JP2009509682A (ja) * | 2005-09-30 | 2009-03-12 | バイテリス，インコーポレイテッド | 予め充填された結合電気搬送パッチからの性腺刺激ホルモン放出ホルモンのパルス状搬送 |
| EP1931416A2 (en) * | 2005-09-30 | 2008-06-18 | Tti Ellebeau, Inc. | Iontophoresis method and apparatus for systemic delivery of active agents |
| US20070078372A1 (en) * | 2005-09-30 | 2007-04-05 | Vyteris, Inc. | Iontophoresis Drug Delivery Formulation Providing Acceptable Sensation and Dermal Anesthesia |
| US20070093743A1 (en) * | 2005-09-30 | 2007-04-26 | Vyteris, Inc. | Iontophoresis Drug Delivery Device Providing Acceptable Depth and Duration of Dermal Anesthesia |
| US20070083147A1 (en) * | 2005-09-30 | 2007-04-12 | Transcutaneous Technologies Inc. | Iontophoresis apparatus and method to deliver antibiotics to biological interfaces |
| JP2009509657A (ja) | 2005-09-30 | 2009-03-12 | Ｔｔｉ・エルビュー株式会社 | 生体界面への活性物質の送達のイオントフォレーシス装置及び方法 |
| JP5116482B2 (ja) * | 2005-11-14 | 2013-01-09 | 帝國製薬株式会社 | イオントフォレーシス用製剤 |
| US7848801B2 (en) | 2005-12-30 | 2010-12-07 | Tti Ellebeau, Inc. | Iontophoretic systems, devices, and methods of delivery of active agents to biological interface |
| US8483820B2 (en) * | 2006-10-05 | 2013-07-09 | Bioness Inc. | System and method for percutaneous delivery of electrical stimulation to a target body tissue |
| US8332028B2 (en) * | 2006-11-28 | 2012-12-11 | Polyplus Battery Company | Protected lithium electrodes for electro-transport drug delivery |
| US8062783B2 (en) | 2006-12-01 | 2011-11-22 | Tti Ellebeau, Inc. | Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices |
| EP2123259A1 (en) * | 2007-01-16 | 2009-11-25 | Hokkaido University | Liposome preparation for iontophoresis having antioxidant component encapsulated therein |
| US7844345B2 (en) * | 2007-02-08 | 2010-11-30 | Neuropace, Inc. | Drug eluting lead systems |
| US7813811B2 (en) * | 2007-02-08 | 2010-10-12 | Neuropace, Inc. | Refillable reservoir lead systems |
| WO2008101171A2 (en) * | 2007-02-16 | 2008-08-21 | Thermage, Inc. | Temperature sensing apparatus and methods for treatment devices used to deliver high frequency energy to tissue |
| US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
| WO2009006349A2 (en) * | 2007-06-29 | 2009-01-08 | Polyplus Battery Company | Electrotransport devices, methods and drug electrode assemblies |
| US7945320B2 (en) * | 2007-08-17 | 2011-05-17 | Isis Biopolymer, Inc. | Iontophoretic drug delivery system |
| US8738137B2 (en) * | 2007-08-23 | 2014-05-27 | Bioness Inc. | System for transmitting electrical current to a bodily tissue |
| US9757554B2 (en) | 2007-08-23 | 2017-09-12 | Bioness Inc. | System for transmitting electrical current to a bodily tissue |
| CA2697381A1 (en) * | 2007-08-23 | 2009-02-26 | Bioness, Inc. | System for transmitting electrical current to a bodily tissue |
| US20090069740A1 (en) * | 2007-09-07 | 2009-03-12 | Polyplus Battery Company | Protected donor electrodes for electro-transport drug delivery |
| US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
| WO2010027771A1 (en) | 2008-08-27 | 2010-03-11 | Edwards Lifesciences Corporation | Analyte sensor |
| PL2401027T3 (pl) | 2009-02-26 | 2018-04-30 | The University Of North Carolina At Chapel Hill | Układ do interwencyjnego dostarczania leku |
| US20110092881A1 (en) * | 2009-05-08 | 2011-04-21 | Isis Biopolymer Inc. | Iontophoretic device with contact sensor |
| CN102421480A (zh) * | 2009-05-08 | 2012-04-18 | 伊思伊思生物高分子公司 | 具有改善的反电极的离子电渗设备 |
| WO2011002776A1 (en) * | 2009-06-29 | 2011-01-06 | Nitric Biotherapeutics, Inc. | Pharmaceutical formulations for iontophoretic delivery of an immunomodulator |
| JP5463136B2 (ja) | 2009-12-22 | 2014-04-09 | 帝國製薬株式会社 | イオントフォレーシス療法に用いる電極装置 |
| USD678534S1 (en) | 2010-07-20 | 2013-03-19 | Iontera, Inc. | Iontophoretic device for application to the brow/forehead of a person |
| WO2012086700A1 (ja) * | 2010-12-22 | 2012-06-28 | 帝國製薬株式会社 | イオントフォレシス用の電極パッド |
| US9610440B2 (en) * | 2013-06-10 | 2017-04-04 | Iontera, Inc | Systems, devices, and methods for transdermal delivery |
| GB2524777A (en) * | 2014-04-02 | 2015-10-07 | Microarray Ltd | Dressing comprising electrodes |
| CN104287714A (zh) * | 2014-11-10 | 2015-01-21 | 青岛柏恩鸿泰电子科技有限公司 | 一种银/氯化银粉末电极 |
| CN107405483A (zh) * | 2015-03-09 | 2017-11-28 | 皇家飞利浦有限公司 | 离子电渗的设备、装置和方法 |
| EP3400985A4 (en) * | 2016-01-05 | 2019-07-31 | Biosensor Laboratories Inc. | IONTOPHORESIS DEVICE FOR DISPOSING A MEDICAMENT AND METHOD FOR THE PRODUCTION THEREOF |
| US12324792B2 (en) | 2020-12-28 | 2025-06-10 | Smith & Nephew, Inc. | Methods for making and using pharmaceutical compositions for iontophoresis |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4416274A (en) | 1981-02-23 | 1983-11-22 | Motion Control, Inc. | Ion mobility limiting iontophoretic bioelectrode |
| JPS5810066A (ja) * | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
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| US5135477A (en) | 1984-10-29 | 1992-08-04 | Medtronic, Inc. | Iontophoretic drug delivery |
| US4752285B1 (en) | 1986-03-19 | 1995-08-22 | Univ Utah Res Found | Methods and apparatus for iontophoresis application of medicaments |
| US5496266A (en) * | 1990-04-30 | 1996-03-05 | Alza Corporation | Device and method of iontophoretic drug delivery |
| US4989607A (en) * | 1989-03-30 | 1991-02-05 | Preston Keusch | Highly conductive non-stringy adhesive hydrophilic gels and medical electrode assemblies manufactured therefrom |
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| FI944321L (fi) | 1992-11-05 | 1994-11-16 | Becton Dickinson Co | Käyttäjäaktivoitu iontoforeettinen laite ja menetelmä sen käyttämiseksi |
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| US5990179A (en) * | 1995-04-28 | 1999-11-23 | Alza Corporation | Composition and method of enhancing electrotransport agent delivery |
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| FR2755372B1 (fr) * | 1996-11-07 | 1998-12-24 | Elf Aquitaine | Dispositif d'ionophorese comportant au moins un ensemble electrode a membrane, pour l'administration transcutanee de principes actifs a un sujet |
| DE69721293T2 (de) | 1996-11-14 | 2004-01-29 | Alza Corp | Einrichtung zur verabreichung von substanzen wie lidocain und epinephrin mit unterstuetzung von elektrischem strom |
| US6004577A (en) * | 1997-08-12 | 1999-12-21 | Murdock; Thomas O. | Enhanced electrotransport of therapeutic agents having polybasic anionic counter ions |
| US5882677A (en) * | 1997-09-30 | 1999-03-16 | Becton Dickinson And Company | Iontophoretic patch with hydrogel reservoir |
| US6295469B1 (en) * | 1997-11-14 | 2001-09-25 | Alza Corporation | Formulation for electrically assisted delivery of lidocaine and epinephrine |
| US6496727B1 (en) * | 2000-05-31 | 2002-12-17 | Becton, Dickinson And Company | Medicament-loaded transdermal reservoir and method for its formation |
-
2000
- 2000-06-30 US US09/610,563 patent/US6629968B1/en not_active Expired - Fee Related
-
2001
- 2001-06-29 JP JP2002506803A patent/JP4024673B2/ja not_active Expired - Fee Related
- 2001-06-29 CA CA002413624A patent/CA2413624C/en not_active Expired - Fee Related
- 2001-06-29 US US09/897,698 patent/US6635045B2/en not_active Expired - Fee Related
- 2001-06-29 WO PCT/US2001/020886 patent/WO2002002182A2/en not_active Ceased
- 2001-06-29 DE DE60129965T patent/DE60129965T2/de not_active Expired - Lifetime
- 2001-06-29 AT AT01952340T patent/ATE369891T1/de not_active IP Right Cessation
- 2001-06-29 AU AU2001273104A patent/AU2001273104A1/en not_active Abandoned
- 2001-06-29 EP EP01952340A patent/EP1294439B1/en not_active Expired - Lifetime
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