JP2004248507A5 - - Google Patents
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- Publication number
- JP2004248507A5 JP2004248507A5 JP2002292682A JP2002292682A JP2004248507A5 JP 2004248507 A5 JP2004248507 A5 JP 2004248507A5 JP 2002292682 A JP2002292682 A JP 2002292682A JP 2002292682 A JP2002292682 A JP 2002292682A JP 2004248507 A5 JP2004248507 A5 JP 2004248507A5
- Authority
- JP
- Japan
- Prior art keywords
- neural progenitor
- cells
- neural
- stem cells
- undifferentiated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 210000005155 neural progenitor cell Anatomy 0.000 description 19
- 238000012258 culturing Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 230000004069 differentiation Effects 0.000 description 5
- 210000001671 embryonic stem cell Anatomy 0.000 description 5
- 210000000130 stem cell Anatomy 0.000 description 5
- 210000002257 embryonic structure Anatomy 0.000 description 3
- 210000002950 fibroblast Anatomy 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 210000000653 nervous system Anatomy 0.000 description 3
- 210000003061 neural cell Anatomy 0.000 description 3
- 230000001537 neural effect Effects 0.000 description 3
- 239000012679 serum free medium Substances 0.000 description 3
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 description 2
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 description 2
- 230000030833 cell death Effects 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 210000001705 ectoderm cell Anatomy 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 210000001178 neural stem cell Anatomy 0.000 description 2
- 210000004498 neuroglial cell Anatomy 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 208000027205 Congenital disease Diseases 0.000 description 1
- 101000595198 Homo sapiens Podocalyxin Proteins 0.000 description 1
- 102000012411 Intermediate Filament Proteins Human genes 0.000 description 1
- 108010061998 Intermediate Filament Proteins Proteins 0.000 description 1
- 102000008730 Nestin Human genes 0.000 description 1
- 108010088225 Nestin Proteins 0.000 description 1
- 102000007354 PAX6 Transcription Factor Human genes 0.000 description 1
- 108010032788 PAX6 Transcription Factor Proteins 0.000 description 1
- 102100036031 Podocalyxin Human genes 0.000 description 1
- 102000013127 Vimentin Human genes 0.000 description 1
- 108010065472 Vimentin Proteins 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
- 210000002459 blastocyst Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004289 cerebral ventricle Anatomy 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 210000005055 nestin Anatomy 0.000 description 1
- 230000004770 neurodegeneration Effects 0.000 description 1
- 208000015122 neurodegenerative disease Diseases 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 210000001778 pluripotent stem cell Anatomy 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000025366 tissue development Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000005048 vimentin Anatomy 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/970,543 US7011828B2 (en) | 2000-03-14 | 2001-10-04 | Implanting neural progenitor cells derived for human embryonic stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008101883A Division JP2008201792A (ja) | 2001-10-04 | 2008-04-09 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004248507A JP2004248507A (ja) | 2004-09-09 |
| JP2004248507A5 true JP2004248507A5 (https=) | 2006-02-23 |
Family
ID=25517110
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002292682A Withdrawn JP2004248507A (ja) | 2001-10-04 | 2002-10-04 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
| JP2008101883A Pending JP2008201792A (ja) | 2001-10-04 | 2008-04-09 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008101883A Pending JP2008201792A (ja) | 2001-10-04 | 2008-04-09 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7011828B2 (https=) |
| EP (1) | EP1302536A3 (https=) |
| JP (2) | JP2004248507A (https=) |
| AU (1) | AU2002301347B2 (https=) |
| CA (1) | CA2406610A1 (https=) |
| IL (1) | IL152106A0 (https=) |
| SG (1) | SG144689A1 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2403000C (en) * | 2000-03-14 | 2015-06-23 | Es Cell International Pte Ltd | Embryonic stem cells and neural progenitor cells derived therefrom |
| US20080268054A1 (en) * | 2000-12-04 | 2008-10-30 | Eugene Bell | Dermal derived human stem cells and compositions and methods thereof |
| US7566101B2 (en) * | 2002-07-15 | 2009-07-28 | Hennessy Industries, Inc. | Vehicle wheel balance weights |
| WO2004099395A2 (en) * | 2003-05-08 | 2004-11-18 | Cellartis Ab | A method for the generation of neural progenitor cells |
| US7638328B2 (en) * | 2003-05-08 | 2009-12-29 | Cellartis Ab | Method for efficient transfer of human blastocyst-derived stem cells (hBS cells) from a feeder-supported to a feeder-free culture system, long-term propagation of hBS cells under feeder-free conditions and use of cultured hBS cells for applications in myocardial regeneration |
| JP4389037B2 (ja) * | 2003-06-03 | 2009-12-24 | 独立行政法人理化学研究所 | Ｅｓ細胞の電気パルス処理によって得られた神経細胞 |
| EP1743012A4 (en) * | 2004-04-09 | 2008-08-27 | Ronald S Coldstein | METHODS OF GENERATING NEURONAL CELLS FROM HUMAN EMBRYONIC STEM CELLS AND THEIR APPLICATIONS |
| US20080044395A1 (en) * | 2004-04-13 | 2008-02-21 | Sungkwang Educational Foundation | In Vitro Method for Isolating, Proliferating and Differentiating Germ-Line Stem Cells |
| US7622108B2 (en) | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
| WO2005108559A2 (en) | 2004-04-23 | 2005-11-17 | Bioe, Inc. | Multi-lineage progenitor cells |
| JP2006149329A (ja) * | 2004-12-01 | 2006-06-15 | Univ Of Tokyo | 繊毛上皮細胞調製方法 |
| JP2006204292A (ja) * | 2004-12-27 | 2006-08-10 | Asahi Kasei Corp | ヒト胚性幹細胞分化抑制剤 |
| EP1856248A4 (en) * | 2005-02-09 | 2010-01-20 | Burnham Inst Medical Research | HOMOGENEOUS NEURALE CURRENT CELLS |
| US9295543B2 (en) * | 2005-03-17 | 2016-03-29 | Stratatech Corporation | Skin substitutes with improved purity |
| US8999706B2 (en) * | 2005-04-12 | 2015-04-07 | The Trustees Of The University Of Pennsylvania | Methods for preparation of human hair-follicle derived multipotent adult stem cells |
| BRPI0617085A2 (pt) * | 2005-09-02 | 2016-11-08 | Agency Science Tech & Res | método para obter uma célula-tronco mesenquimal (msc), célula ou linhagem celular, método para derivar uma cultura celular a partir de uma célula-tronco embrionária, método para tratamento de uma doença, uso de uma célula-tronco mesenquimal, linhagem diferenciada, composição farmacêutica, método para condicionar um meio de cultura celular, meio condicionado e uso do mesmo, mpetodo para obterum polipeptídeo, método para obtar uma cultura celular, cultura celular, célula-tronco mesenquimal, linhagem de célula-tronco mesenquimal ou uma célula mesenquimal diferenciada |
| ITNA20060017A1 (it) * | 2006-02-20 | 2007-08-21 | Aquino Riccardo D | Tecnica di prelievo e selezione di un una popolazione di cellule staminali di tipo embrionale da tessuti follicolari peridentari di uomo adulto. |
| CA2646491A1 (en) | 2006-04-17 | 2007-10-25 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
| US20080003681A1 (en) * | 2006-06-28 | 2008-01-03 | Mahalaxmi Gita Bangera | Methods for altering cellular susceptibility to infection |
| GB0622394D0 (en) * | 2006-11-09 | 2006-12-20 | Univ Cambridge Tech | Differentiation of pluripotent cells |
| RU2341270C2 (ru) * | 2006-12-28 | 2008-12-20 | Александр Сергеевич Ботин | Композиция для стимулирования роста и регенерации клеток, а также способы ее получения |
| EP2192908A4 (en) * | 2007-07-25 | 2010-09-01 | Bioe Inc | DIFFERENTIATION OF PRECURSOR CELLS OF MULTIPLE ABSTRACTS AGAINST CHONDROCYTES |
| US8338176B2 (en) * | 2007-07-30 | 2012-12-25 | The Board Of Trustees Of The Leland Stanford Junior University | Derivation of neural stem cells from embryonic stem cells |
| EP2185694A2 (en) | 2007-08-02 | 2010-05-19 | California Stem Cell, Inc. | Neuronal progenitor cells and methods of derivation and purification of neuronal progenitor cells from embryonic stem cells |
| KR101175175B1 (ko) * | 2008-07-28 | 2012-08-20 | 서울대학교병원 | 인간 줄기세포에서 고활성 줄기세포를 분리하는 방법 및상기 방법에 의해 분리된 고활성 줄기 세포 |
| US8642334B2 (en) | 2009-02-17 | 2014-02-04 | Memorial Sloan Kettering Cancer Center | Methods of neural conversion of human embryonic stem cells |
| JP5783504B2 (ja) * | 2009-03-30 | 2015-09-24 | 国立研究開発法人国立環境研究所 | 胎生プログラミングに対する影響を評価するための方法 |
| US20110052549A1 (en) * | 2009-08-27 | 2011-03-03 | The Regents Of The University Of California | Cell culture device to differentiate stem cells in a specific orientation |
| US20110091427A1 (en) * | 2009-10-02 | 2011-04-21 | Baxter International Inc. | Methods for treating a kidney injury |
| EP2512514B1 (en) | 2009-12-14 | 2014-11-05 | Kyoto University | Screening method for identifying compounds for treating amyotrophic lateral sclerosis |
| AU2011279250B2 (en) | 2010-07-12 | 2014-12-04 | California Institute Of Technology | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| CN103429734A (zh) * | 2010-10-26 | 2013-12-04 | 卡斯西部储备大学 | 用于产生神经胶质细胞的群体的分化方法 |
| JP6185907B2 (ja) * | 2011-03-30 | 2017-08-23 | セルラー ダイナミクス インターナショナル， インコーポレイテッド | 神経分化のための多能性幹細胞の予備刺激 |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| PT2773748T (pt) | 2011-11-04 | 2020-03-26 | Memorial Sloan Kettering Cancer Center | Neurónios dopaminérgicos (da) do mesencéfalo para enxerto |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| JP2015508101A (ja) | 2012-02-21 | 2015-03-16 | バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ | Ｃｄ３４＋細胞を含む薬学的組成物 |
| EP2829605B1 (en) | 2012-03-21 | 2019-05-08 | Kyoto University | Method for screening therapeutic and/or prophylactic agents for alzheimer's disease |
| JP6300807B2 (ja) * | 2012-10-16 | 2018-03-28 | メルツ ファルマ ゲーエムベーハー ウント コンパニー カーゲーアーアー | 神経毒素ポリペプチドの生物学的活性の決定のための細胞試験系 |
| CN105431522B (zh) | 2013-03-14 | 2021-08-03 | 加利福尼亚大学董事会 | 内侧神经节隆起前体细胞的体外产生 |
| EP3498824A1 (en) | 2013-04-26 | 2019-06-19 | Memorial Sloan-Kettering Cancer Center | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
| JP6723918B2 (ja) | 2013-11-21 | 2020-07-15 | メモリアル スローン ケタリング キャンサー センター | ヒト多能性幹細胞からの機能的頭蓋プラコード派生体の特定 |
| JP6329468B2 (ja) * | 2014-09-16 | 2018-05-23 | 三菱製紙株式会社 | 線維芽細胞のガラス化凍結保存方法 |
| CA2971901C (en) * | 2014-12-24 | 2022-06-21 | Neuorphan Pty Ltd | Improvements in oligodendroglial cell culturing methods and in methods for treating neurodegenerative disorders by using thyroid hormones or analogues |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
| DE19756864C5 (de) | 1997-12-19 | 2014-07-10 | Oliver Brüstle | Neurale Vorläuferzellen, Verfahren zu ihrer Herstellung und ihre Verwendung zur Therapie von neuralen Defekten |
| WO2000027995A1 (en) * | 1998-11-09 | 2000-05-18 | Monash University | Embryonic stem cells |
| CA2403000C (en) | 2000-03-14 | 2015-06-23 | Es Cell International Pte Ltd | Embryonic stem cells and neural progenitor cells derived therefrom |
| AU779694B2 (en) * | 2000-03-14 | 2005-02-03 | Es Cell International Pte Ltd | Embryonic stem cells and neural progenitor cells derived therefrom |
| JP5943533B2 (ja) * | 2000-05-17 | 2016-07-06 | アステリアス バイオセラピューティクス インコーポレイテッド | 神経前駆細胞の集団 |
-
2001
- 2001-10-04 US US09/970,543 patent/US7011828B2/en not_active Expired - Lifetime
-
2002
- 2002-10-03 IL IL15210602A patent/IL152106A0/xx unknown
- 2002-10-03 CA CA002406610A patent/CA2406610A1/en not_active Abandoned
- 2002-10-04 AU AU2002301347A patent/AU2002301347B2/en not_active Ceased
- 2002-10-04 EP EP02256974A patent/EP1302536A3/en not_active Withdrawn
- 2002-10-04 SG SG200206039-0A patent/SG144689A1/en unknown
- 2002-10-04 JP JP2002292682A patent/JP2004248507A/ja not_active Withdrawn
-
2008
- 2008-04-09 JP JP2008101883A patent/JP2008201792A/ja active Pending
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