JP2004215669A5 - - Google Patents

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Publication number
JP2004215669A5
JP2004215669A5 JP2004064978A JP2004064978A JP2004215669A5 JP 2004215669 A5 JP2004215669 A5 JP 2004215669A5 JP 2004064978 A JP2004064978 A JP 2004064978A JP 2004064978 A JP2004064978 A JP 2004064978A JP 2004215669 A5 JP2004215669 A5 JP 2004215669A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004064978A
Other languages
Japanese (ja)
Other versions
JP2004215669A (ja
JP3811745B2 (ja
Filing date
Publication date
Priority claimed from DE19944412177 external-priority patent/DE4412177C1/de
Application filed filed Critical
Publication of JP2004215669A publication Critical patent/JP2004215669A/ja
Publication of JP2004215669A5 publication Critical patent/JP2004215669A5/ja
Application granted granted Critical
Publication of JP3811745B2 publication Critical patent/JP3811745B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2004064978A 1994-04-08 2004-03-09 アポトーシス阻害剤 Expired - Lifetime JP3811745B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19944412177 DE4412177C1 (de) 1994-04-08 1994-04-08 Hemmer von Apoptose

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP52603195A Division JP3778453B2 (ja) 1994-04-08 1995-02-16 アポプトシス阻害剤

Publications (3)

Publication Number Publication Date
JP2004215669A JP2004215669A (ja) 2004-08-05
JP2004215669A5 true JP2004215669A5 (enExample) 2005-06-09
JP3811745B2 JP3811745B2 (ja) 2006-08-23

Family

ID=6514949

Family Applications (2)

Application Number Title Priority Date Filing Date
JP52603195A Expired - Lifetime JP3778453B2 (ja) 1994-04-08 1995-02-16 アポプトシス阻害剤
JP2004064978A Expired - Lifetime JP3811745B2 (ja) 1994-04-08 2004-03-09 アポトーシス阻害剤

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP52603195A Expired - Lifetime JP3778453B2 (ja) 1994-04-08 1995-02-16 アポプトシス阻害剤

Country Status (8)

Country Link
US (1) US20070207160A1 (enExample)
EP (1) EP0705278B1 (enExample)
JP (2) JP3778453B2 (enExample)
AT (1) ATE255129T1 (enExample)
DE (1) DE4447484C2 (enExample)
DK (1) DK0705278T3 (enExample)
ES (1) ES2211899T3 (enExample)
WO (1) WO1995027735A1 (enExample)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
DE69636170T2 (de) * 1995-03-20 2006-11-02 Okumura, Ko Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellung
AU6091496A (en) * 1995-06-07 1996-12-30 Chiron Corporation Antibodies to fas antigen capable of inhibiting apoptosis
US6096312A (en) * 1995-06-30 2000-08-01 Mochida Pharmaceutical Co., Ltd. Agent for suppressing a reduction of CD4+ lymphocytes
JPH09124509A (ja) * 1995-10-27 1997-05-13 Sumitomo Electric Ind Ltd 肝炎治療剤
DE19544333C2 (de) * 1995-11-28 1998-12-10 Deutsches Krebsforsch Verfahren zur Beurteilung der Aktivität von Arzneistoffen
AU2814897A (en) * 1996-04-25 1997-11-12 T Cell Sciences, Inc. Method of isolating regulators of t cell activation
GB9703276D0 (en) * 1997-02-17 1997-04-09 Screaton Gavin R Materials and methods relating to the protection of useful immune cells
AU1288099A (en) * 1997-10-30 1999-05-24 Cornell Research Foundation Inc. A method of inhibiting an immune response to a recombinant vector
EP1447093A1 (en) * 2003-02-14 2004-08-18 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Inhibition of the CD95 ligand/receptor system for the treatment of neurological disorders and injuries
JP2007533595A (ja) * 2003-03-26 2007-11-22 アポゲニクス ゲゼルシャフト ミット ベシュレンクテル ハフツング ウィルス感染の治療
DK2101877T3 (da) 2006-12-28 2013-09-23 Deutsches Krebsforsch Neutralisering af virkningen af CD95 til blokering af invasion af glioblastomceller in vivo
WO2010003766A2 (en) 2008-06-17 2010-01-14 Apogenix Gmbh Multimeric tnf receptors
EP2456468A1 (en) * 2009-07-21 2012-05-30 Queen Mary and Westfield College Fas (apo-1, cd95) targeted platforms for intracellular drug delivery
JP6297552B2 (ja) 2012-07-18 2018-03-20 アポジェニックス アーゲー Mdsの治療のための、cd95シグナル伝達経路阻害剤
EP3076179A1 (en) 2015-03-30 2016-10-05 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Diagnosis and treatment of low grade gliomas
TWI788307B (zh) 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
CN110462027A (zh) 2017-01-06 2019-11-15 艾欧凡斯生物治疗公司 用肿瘤坏死因子受体超家族(tnfrsf)激动剂扩增肿瘤浸润淋巴细胞(til)及til和tnfrsf激动剂的治疗组合
CA3049165A1 (en) 2017-01-06 2018-07-12 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
IL270412B2 (en) 2017-05-10 2025-03-01 Iovance Biotherapeutics Inc Expansion of infiltrating lymphocytes from liquid samples and their medical uses
EP3714041A1 (en) 2017-11-22 2020-09-30 Iovance Biotherapeutics, Inc. Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
WO2019118873A2 (en) 2017-12-15 2019-06-20 Iovance Biotherapeutics, Inc. Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof
EP3752600A1 (en) 2018-02-13 2020-12-23 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes (tils) with adenosine a2a receptor antagonists and therapeutic combinations of tils and adenosine a2a receptor antagonists
MX2021010288A (es) 2019-03-01 2021-09-23 Iovance Biotherapeutics Inc Expansion de linfocitos infiltrantes de tumores a partir de tumores liquidos y usos terapeuticos de los mismos.
EP3946437B1 (en) 2019-03-29 2025-11-19 H. Lee Moffitt Cancer Center and Research Institute, Inc. Ex vivo methods for producing a t cell therapeutic and related compositions and methods
CN115023270A (zh) 2019-11-27 2022-09-06 迈斯特治疗公司 使用调节剂产生肿瘤反应性t细胞组合物的方法
IL295990A (en) 2020-02-27 2022-11-01 Myst Therapeutics Llc Methods for in vitro enrichment and expansion of tumor-reactive t cells and preparations related thereto
WO2024098024A1 (en) 2022-11-04 2024-05-10 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486344A (en) * 1983-03-28 1984-12-04 Miles Laboratories, Inc. Urea-linked immunogens, antibodies, and preparative method
DK354487A (da) * 1986-07-11 1988-01-12 Noboru Yanaihara Oncogen-relaterede peptider
PT90657B (pt) * 1988-05-27 1995-03-01 Ortho Pharma Corp Processo para a preparacao de peptidos que bloqueiam a ligacao de hiv-1 a proteina cd4 receptora
AU7677891A (en) * 1990-03-30 1991-10-30 Smithkline Beecham Corporation Inhibition of disease associated with immunodeficiency virus infection
DE69233441T2 (de) * 1991-04-26 2005-10-13 Osaka Bioscience Institute, Suita Menschliches Zelloberflächen-Antigen codierende DNA
NZ275711A (en) * 1993-10-14 1998-03-25 Immunex Corp Monoclonal antibodies and binding proteins which bind to human fas antigen (nerve growth factor/tumour necrosis factor receptor type)
US5830469A (en) * 1993-10-14 1998-11-03 Immunex Corporation Fas antagonists and uses thereof

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