JP2004049003A5 - - Google Patents

Info

Publication number

JP2004049003A5

JP2004049003A5 JP2002172382A JP2002172382A JP2004049003A5 JP 2004049003 A5 JP2004049003 A5 JP 2004049003A5 JP 2002172382 A JP2002172382 A JP 2002172382A JP 2002172382 A JP2002172382 A JP 2002172382A JP 2004049003 A5 JP2004049003 A5 JP 2004049003A5

Authority

JP

Japan

Prior art keywords

amino acid

acid sequence

seq

salt

peptide

Prior art date

2002-06-13

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 108090000765 processed proteins & peptides Proteins 0.000 claims 117
• 125000003275 alpha amino acid group Chemical group 0.000 claims 112
• 150000003839 salts Chemical class 0.000 claims 107
• 150000002148 esters Chemical class 0.000 claims 55
• 150000001408 amides Chemical class 0.000 claims 53
• 108090000623 proteins and genes Proteins 0.000 claims 38
• 102000004169 proteins and genes Human genes 0.000 claims 38
• 150000001875 compounds Chemical class 0.000 claims 22
• 239000003814 drug Substances 0.000 claims 16
• 102000040430 polynucleotide Human genes 0.000 claims 15
• 108091033319 polynucleotide Proteins 0.000 claims 15
• 239000002157 polynucleotide Substances 0.000 claims 15
• 239000002243 precursor Substances 0.000 claims 13
• 238000012216 screening Methods 0.000 claims 12
• 206010020710 Hyperphagia Diseases 0.000 claims 7
• 208000008589 Obesity Diseases 0.000 claims 7
• 235000020824 obesity Nutrition 0.000 claims 7
• 229940124597 therapeutic agent Drugs 0.000 claims 7
• 239000000032 diagnostic agent Substances 0.000 claims 6
• 229940039227 diagnostic agent Drugs 0.000 claims 6
• 238000000034 method Methods 0.000 claims 6
• 125000000729 N-terminal amino-acid group Chemical group 0.000 claims 5
• 239000002948 appetite stimulant Substances 0.000 claims 5
• 208000000103 Anorexia Nervosa Diseases 0.000 claims 4
• 230000003449 preventive effect Effects 0.000 claims 4
• 239000000556 agonist Substances 0.000 claims 3
• 208000022531 anorexia Diseases 0.000 claims 3
• 239000005557 antagonist Substances 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 206010061428 decreased appetite Diseases 0.000 claims 3
• 230000000069 prophylactic effect Effects 0.000 claims 3
• 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 claims 3
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 230000000295 complement effect Effects 0.000 claims 1
• 230000007423 decrease Effects 0.000 claims 1
• 230000000694 effects Effects 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 230000003472 neutralizing effect Effects 0.000 claims 1