JP2003532675A - 癌細胞の増殖を阻害しそのアポトーシスを誘導する方法 - Google Patents
癌細胞の増殖を阻害しそのアポトーシスを誘導する方法Info
- Publication number
- JP2003532675A JP2003532675A JP2001581820A JP2001581820A JP2003532675A JP 2003532675 A JP2003532675 A JP 2003532675A JP 2001581820 A JP2001581820 A JP 2001581820A JP 2001581820 A JP2001581820 A JP 2001581820A JP 2003532675 A JP2003532675 A JP 2003532675A
- Authority
- JP
- Japan
- Prior art keywords
- leukotriene
- alkyl
- compound
- ethyl
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21934400P | 2000-05-09 | 2000-05-09 | |
US60/219,344 | 2000-05-09 | ||
PCT/US2001/040697 WO2001085166A1 (en) | 2000-05-09 | 2001-05-08 | Methods for inhibiting proliferation and inducing apoptosis in cancer cells |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2003532675A true JP2003532675A (ja) | 2003-11-05 |
Family
ID=22818912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001581820A Pending JP2003532675A (ja) | 2000-05-09 | 2001-05-08 | 癌細胞の増殖を阻害しそのアポトーシスを誘導する方法 |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1326605A4 (zh) |
JP (1) | JP2003532675A (zh) |
KR (1) | KR20030019372A (zh) |
CN (1) | CN1237968C (zh) |
AU (1) | AU2001261832A1 (zh) |
BR (1) | BR0110473A (zh) |
CA (1) | CA2408622A1 (zh) |
MX (1) | MXPA02010974A (zh) |
NO (1) | NO20025343L (zh) |
NZ (1) | NZ522387A (zh) |
WO (1) | WO2001085166A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5858391B2 (ja) * | 2013-04-22 | 2016-02-10 | 株式会社栃木臨床病理研究所 | 抗腫瘍剤 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6797723B1 (en) | 1999-11-11 | 2004-09-28 | Eli Lilly And Company | Heterocycle substituted diphenyl leukotriene antagonists |
US7012100B1 (en) | 2002-06-04 | 2006-03-14 | Avolix Pharmaceuticals, Inc. | Cell migration inhibiting compositions and methods and compositions for treating cancer |
EP2034022A1 (en) * | 2007-09-10 | 2009-03-11 | Universite Libre De Bruxelles | Leukotriene B4 binding soluble lipocalin receptor from ixodes ricinus |
MX2014008452A (es) | 2012-01-10 | 2014-08-27 | Lilly Co Eli | Compuesto antagonista del leucotrieno b4. |
UA117498C2 (uk) | 2013-12-20 | 2018-08-10 | Новартіс Аг | Гетероарильні похідні бутанової кислоти як інгібітори lta4h |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH30449A (en) * | 1991-11-25 | 1997-05-28 | Lilly Co Eli | Substituted phenyl phenol leukotriene antagonists |
WO1996006604A2 (en) * | 1994-08-31 | 1996-03-07 | Eli Lilly And Company | Methods for identifying and treating resistant tumors |
HUP9904672A2 (hu) * | 1997-03-21 | 2000-05-28 | Eli Lilly And Co. | Szájüregi laphámrák ellen alkalmazható leukotrién antagonisták |
AU1916501A (en) * | 1999-11-11 | 2001-06-06 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
WO2001034135A2 (en) * | 1999-11-11 | 2001-05-17 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
AU1916601A (en) * | 1999-11-11 | 2001-06-06 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
CN1390139A (zh) * | 1999-11-11 | 2003-01-08 | 伊莱利利公司 | 用于治疗癌症的肿瘤细胞溶解组合物 |
-
2001
- 2001-05-08 JP JP2001581820A patent/JP2003532675A/ja active Pending
- 2001-05-08 BR BR0110473-0A patent/BR0110473A/pt not_active IP Right Cessation
- 2001-05-08 NZ NZ522387A patent/NZ522387A/en unknown
- 2001-05-08 EP EP01935770A patent/EP1326605A4/en not_active Withdrawn
- 2001-05-08 MX MXPA02010974A patent/MXPA02010974A/es unknown
- 2001-05-08 KR KR1020027015033A patent/KR20030019372A/ko not_active Application Discontinuation
- 2001-05-08 WO PCT/US2001/040697 patent/WO2001085166A1/en not_active Application Discontinuation
- 2001-05-08 AU AU2001261832A patent/AU2001261832A1/en not_active Abandoned
- 2001-05-08 CA CA002408622A patent/CA2408622A1/en not_active Abandoned
- 2001-05-08 CN CNB018093299A patent/CN1237968C/zh not_active Expired - Fee Related
-
2002
- 2002-11-07 NO NO20025343A patent/NO20025343L/no not_active Application Discontinuation
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5858391B2 (ja) * | 2013-04-22 | 2016-02-10 | 株式会社栃木臨床病理研究所 | 抗腫瘍剤 |
JP2016094403A (ja) * | 2013-04-22 | 2016-05-26 | 株式会社栃木臨床病理研究所 | 抗腫瘍剤 |
US9775836B2 (en) | 2013-04-22 | 2017-10-03 | Tochigi Institute Of Clinical Pathology | Antitumor agent |
US10149846B2 (en) | 2013-04-22 | 2018-12-11 | Tochigi Institute Of Clinical Pathology | Antitumor agent |
US10729683B2 (en) | 2013-04-22 | 2020-08-04 | Tochigi Institute Of Clinical Pathology | Antitumor agent |
Also Published As
Publication number | Publication date |
---|---|
EP1326605A4 (en) | 2004-03-17 |
CN1237968C (zh) | 2006-01-25 |
KR20030019372A (ko) | 2003-03-06 |
AU2001261832A1 (en) | 2001-11-20 |
NZ522387A (en) | 2003-09-26 |
EP1326605A1 (en) | 2003-07-16 |
MXPA02010974A (es) | 2004-09-06 |
NO20025343D0 (no) | 2002-11-07 |
NO20025343L (no) | 2003-01-09 |
CN1429111A (zh) | 2003-07-09 |
CA2408622A1 (en) | 2001-11-15 |
BR0110473A (pt) | 2003-04-01 |
WO2001085166A1 (en) | 2001-11-15 |
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