JP2003529593A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003529593A5 JP2003529593A5 JP2001572483A JP2001572483A JP2003529593A5 JP 2003529593 A5 JP2003529593 A5 JP 2003529593A5 JP 2001572483 A JP2001572483 A JP 2001572483A JP 2001572483 A JP2001572483 A JP 2001572483A JP 2003529593 A5 JP2003529593 A5 JP 2003529593A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxymutilin
- ester
- carbamic acid
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(CC([C@](C[C@@](*=O)O)*1)C(C)[C@]([C@](C)(*)C2)O)[C@@]1(C)[C@@]2OCNC(*)=O Chemical compound CC(CC([C@](C[C@@](*=O)O)*1)C(C)[C@]([C@](C)(*)C2)O)[C@@]1(C)[C@@]2OCNC(*)=O 0.000 description 9
- UDMSAJCHCPRAST-ISTVENEXSA-N CC(/C=N\C(\C)=C/N)N Chemical compound CC(/C=N\C(\C)=C/N)N UDMSAJCHCPRAST-ISTVENEXSA-N 0.000 description 1
- YKGUXRUBAFSWAN-QVXLNCAUSA-N CC(C)/C=C(\C=C/N)/N Chemical compound CC(C)/C=C(\C=C/N)/N YKGUXRUBAFSWAN-QVXLNCAUSA-N 0.000 description 1
- BOFGYEXXHNKKLA-UHFFFAOYSA-N CC1=CC=CNC1 Chemical compound CC1=CC=CNC1 BOFGYEXXHNKKLA-UHFFFAOYSA-N 0.000 description 1
- MHUGUFYRWAUTBP-UHFFFAOYSA-N Cc(cn1)cc(N)c1OC Chemical compound Cc(cn1)cc(N)c1OC MHUGUFYRWAUTBP-UHFFFAOYSA-N 0.000 description 1
- IWHCRXIOIHHNHX-UHFFFAOYSA-N Cc1c2nccc[n]2nc1 Chemical compound Cc1c2nccc[n]2nc1 IWHCRXIOIHHNHX-UHFFFAOYSA-N 0.000 description 1
- LKYQLOSMAQQSRZ-UHFFFAOYSA-N Cc1c[s]c(C2CCNCC2)n1 Chemical compound Cc1c[s]c(C2CCNCC2)n1 LKYQLOSMAQQSRZ-UHFFFAOYSA-N 0.000 description 1
- QVFHSGHXKXLQGN-UHFFFAOYSA-N Cc1cc(CC=C)c(N=C)nc1 Chemical compound Cc1cc(CC=C)c(N=C)nc1 QVFHSGHXKXLQGN-UHFFFAOYSA-N 0.000 description 1
- DBZRHTFNKRSZTF-UHFFFAOYSA-N Cc1ccnc(C=N)c1 Chemical compound Cc1ccnc(C=N)c1 DBZRHTFNKRSZTF-UHFFFAOYSA-N 0.000 description 1
- GUABFMPMKJGSBQ-UHFFFAOYSA-N Cc1cnc(N)[s]1 Chemical compound Cc1cnc(N)[s]1 GUABFMPMKJGSBQ-UHFFFAOYSA-N 0.000 description 1
- MHZNCOBCMWBPPM-UHFFFAOYSA-N Cc1cnc(N)nc1 Chemical compound Cc1cnc(N)nc1 MHZNCOBCMWBPPM-UHFFFAOYSA-N 0.000 description 1
- TWGNOYAGHYUFFR-UHFFFAOYSA-N Cc1cncnc1 Chemical compound Cc1cncnc1 TWGNOYAGHYUFFR-UHFFFAOYSA-N 0.000 description 1
- NWAGBIGYWRXBAI-UHFFFAOYSA-N Nc1nc(I)c[s]1 Chemical compound Nc1nc(I)c[s]1 NWAGBIGYWRXBAI-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0008260.2 | 2000-04-04 | ||
| GBGB0008260.2A GB0008260D0 (en) | 2000-04-04 | 2000-04-04 | Novel compounds |
| GB0027182.5 | 2000-11-04 | ||
| GB0027182A GB0027182D0 (en) | 2000-11-04 | 2000-11-04 | Novel comounds |
| PCT/EP2001/003594 WO2001074788A1 (en) | 2000-04-04 | 2001-03-29 | 2-hydroxy-mutilin carbamate derivatives for antibacterial use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003529593A JP2003529593A (ja) | 2003-10-07 |
| JP2003529593A5 true JP2003529593A5 (https=) | 2008-05-15 |
Family
ID=26244040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001572483A Pending JP2003529593A (ja) | 2000-04-04 | 2001-03-29 | 抗菌剤として用いるための２−ヒドロキシムチリンカルバメート誘導体 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6972297B2 (https=) |
| EP (1) | EP1268443B1 (https=) |
| JP (1) | JP2003529593A (https=) |
| KR (1) | KR100758441B1 (https=) |
| CN (1) | CN1210267C (https=) |
| AR (1) | AR030203A1 (https=) |
| AT (1) | ATE437860T1 (https=) |
| AU (2) | AU2001263827B2 (https=) |
| BR (1) | BR0109809A (https=) |
| CA (1) | CA2405132A1 (https=) |
| CO (1) | CO5280223A1 (https=) |
| CZ (1) | CZ20023290A3 (https=) |
| DE (1) | DE60139382D1 (https=) |
| ES (1) | ES2328109T3 (https=) |
| HU (1) | HUP0300370A3 (https=) |
| IL (1) | IL151887A0 (https=) |
| MX (1) | MXPA02009816A (https=) |
| NO (1) | NO324229B1 (https=) |
| NZ (1) | NZ521536A (https=) |
| PL (1) | PL358666A1 (https=) |
| WO (1) | WO2001074788A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0024811D0 (en) * | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
| US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
| GB0209262D0 (en) * | 2002-04-23 | 2002-06-05 | Biochemie Gmbh | Organic compounds |
| DE60317208T2 (de) * | 2002-07-24 | 2008-08-07 | Nabriva Therapeutics Forschungs Gmbh | Pleuromutilinderivate als antimikrobielle mittel |
| GB0218578D0 (en) * | 2002-08-09 | 2002-09-18 | Glaxo Group Ltd | Novel method |
| GB0308114D0 (en) * | 2003-04-08 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
| FR2856685B1 (fr) * | 2003-06-25 | 2005-09-23 | Merck Sante Sas | Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| EP1863768A1 (en) * | 2004-12-13 | 2007-12-12 | Glaxo Group Limited | Novel polymorph of (5-amino-6-methoxy-3-pyridincarbonyl)carbamic acid 2-(s)-hydroxymutilin 14-ester |
| CA2591898A1 (en) * | 2004-12-27 | 2006-07-06 | Kyorin Pharmaceutical Co., Ltd. | Mutilin-derivative substituted at position 12 |
| JP2008534443A (ja) * | 2005-03-10 | 2008-08-28 | スミスクライン・ビーチャム・コーポレイション | 新規な方法 |
| TW200738701A (en) | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| KR100695541B1 (ko) * | 2005-10-31 | 2007-03-16 | 한국단자공업 주식회사 | 연결터미널 |
| WO2007079173A2 (en) * | 2005-12-30 | 2007-07-12 | Emergent Biosolutions Inc. | Novel 2-heteroaryloxy-phenol derivatives as antibacterial agents |
| JP5322927B2 (ja) * | 2007-05-24 | 2013-10-23 | 杏林製薬株式会社 | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| EP2014640A1 (en) * | 2007-07-13 | 2009-01-14 | Nabriva Therapeutics AG | Pleuromutilin derivatives |
| JP2010100582A (ja) * | 2008-10-24 | 2010-05-06 | Kyorin Pharmaceut Co Ltd | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| EP2253617A1 (de) | 2009-05-20 | 2010-11-24 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| ES2843723T3 (es) * | 2015-06-17 | 2021-07-20 | Nabriva Therapeutics GmbH | Formulaciones farmacéuticas inyectables de lefamulina |
| JP7631212B2 (ja) | 2019-02-27 | 2025-02-18 | オティカラ，インコーポレーテッド | 鼻、副鼻腔、および鼻咽頭組織の感染および／または炎症を治療するための方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4163254B2 (ja) | 1996-01-03 | 2008-10-08 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ムチリンのカルバモイルオキシ誘導体および抗細菌剤としてのそれらの使用 |
| HUP0001741A3 (en) | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
| UY25225A1 (es) * | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
| FR2771008B1 (fr) | 1997-11-17 | 2000-04-28 | Hoechst Marion Roussel Inc | Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose |
| GB9817029D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Plc | Novel compounds |
-
2001
- 2001-03-29 DE DE60139382T patent/DE60139382D1/de not_active Expired - Lifetime
- 2001-03-29 EP EP01938069A patent/EP1268443B1/en not_active Expired - Lifetime
- 2001-03-29 BR BR0109809-8A patent/BR0109809A/pt not_active Application Discontinuation
- 2001-03-29 ES ES01938069T patent/ES2328109T3/es not_active Expired - Lifetime
- 2001-03-29 CN CNB018091989A patent/CN1210267C/zh not_active Expired - Fee Related
- 2001-03-29 AU AU2001263827A patent/AU2001263827B2/en not_active Ceased
- 2001-03-29 WO PCT/EP2001/003594 patent/WO2001074788A1/en not_active Ceased
- 2001-03-29 JP JP2001572483A patent/JP2003529593A/ja active Pending
- 2001-03-29 NZ NZ521536A patent/NZ521536A/en unknown
- 2001-03-29 PL PL01358666A patent/PL358666A1/xx not_active Application Discontinuation
- 2001-03-29 IL IL15188701A patent/IL151887A0/xx unknown
- 2001-03-29 AT AT01938069T patent/ATE437860T1/de not_active IP Right Cessation
- 2001-03-29 US US10/240,908 patent/US6972297B2/en not_active Expired - Fee Related
- 2001-03-29 MX MXPA02009816A patent/MXPA02009816A/es active IP Right Grant
- 2001-03-29 KR KR1020027013202A patent/KR100758441B1/ko not_active Expired - Fee Related
- 2001-03-29 CZ CZ20023290A patent/CZ20023290A3/cs unknown
- 2001-03-29 HU HU0300370A patent/HUP0300370A3/hu unknown
- 2001-03-29 CA CA002405132A patent/CA2405132A1/en not_active Abandoned
- 2001-03-29 AU AU6382701A patent/AU6382701A/xx not_active Withdrawn
- 2001-03-30 AR ARP010101559A patent/AR030203A1/es not_active Application Discontinuation
- 2001-03-30 CO CO01025487A patent/CO5280223A1/es not_active Application Discontinuation
-
2002
- 2002-10-02 NO NO20024745A patent/NO324229B1/no unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2003529593A5 (https=) | ||
| EP3409667B1 (en) | Amide compounds for the treatment of hiv infections | |
| US10906895B2 (en) | Processes for the preparation of benzodiazepine derivatives | |
| CN109790168B (zh) | 取代的吡咯嗪化合物及其用途 | |
| EP2943481B1 (en) | (hetero)arylacetamide derivatives as antiretroviral agents | |
| JP6524081B2 (ja) | ジヒドロピリミジン化合物及び医薬におけるその適用 | |
| TWI699359B (zh) | ４ｈ-吡咯［３,２-ｃ］吡啶-４-酮衍生物 | |
| CN104428293B (zh) | 调节TNFα的苯并咪唑类 | |
| TWI480282B (zh) | 稠合雜環衍生物及其用途 | |
| KR102932904B1 (ko) | 새로운 화합물 및 그 용도 | |
| CN115443276B (zh) | 吡啶并嘧啶酮衍生物及其作为芳烃受体调节剂的应用 | |
| EA021463B1 (ru) | Пуриновые производные и их применение в качестве модуляторов толл-подобного рецептора 7 | |
| TW202120496A (zh) | 作為cd38抑制劑之雜雙環醯胺 | |
| SG10202111648YA (en) | Chemical compounds | |
| AU2014272776A1 (en) | Pyrazolopyrrolidine derivatives and their use in the treatment of disease | |
| GB0004887D0 (en) | Chemical compounds | |
| CN105121418A (zh) | 苯并噻唑-6-基乙酸衍生物及其治疗hiv感染的用途 | |
| EP2017278A1 (en) | Dihydropyrazolopyrimidinone derivative | |
| EP3412675A1 (en) | Imidazopyrrolidinone derivatives and their use in the treatment of disease | |
| JP2006515373A5 (https=) | ||
| EP3752506B1 (en) | Pyrimidine derivatives for prevention and treatment of bacterial infections | |
| JP2005513020A5 (https=) | ||
| ES2992772T3 (en) | Benzothiazol-6-yl acetic acid derivatives and their use for treating hiv infection | |
| WO2019154329A1 (zh) | 具有bet抑制活性的化合物及其制备方法和用途 | |
| CA2417629A1 (en) | Derivatives of variolin b |