JP2003519176A5 - - Google Patents

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Publication number
JP2003519176A5
JP2003519176A5 JP2001549643A JP2001549643A JP2003519176A5 JP 2003519176 A5 JP2003519176 A5 JP 2003519176A5 JP 2001549643 A JP2001549643 A JP 2001549643A JP 2001549643 A JP2001549643 A JP 2001549643A JP 2003519176 A5 JP2003519176 A5 JP 2003519176A5
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JP
Japan
Prior art keywords
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nitrate
group
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scn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001549643A
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English (en)
Japanese (ja)
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JP2003519176A (ja
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Publication date
Priority claimed from US09/473,713 external-priority patent/US7115661B1/en
Application filed filed Critical
Publication of JP2003519176A publication Critical patent/JP2003519176A/ja
Publication of JP2003519176A5 publication Critical patent/JP2003519176A5/ja
Pending legal-status Critical Current

Links

JP2001549643A 1999-12-29 2000-12-27 痛みを緩和する方法および組成物 Pending JP2003519176A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/473,713 US7115661B1 (en) 1999-12-29 1999-12-29 Methods and compositions for mitigating pain
US09/473,713 1999-12-29
PCT/CA2000/001523 WO2001049275A2 (en) 1999-12-29 2000-12-27 Methods and compositions for mitigating pain using nitrate esters

Publications (2)

Publication Number Publication Date
JP2003519176A JP2003519176A (ja) 2003-06-17
JP2003519176A5 true JP2003519176A5 (https=) 2008-02-21

Family

ID=23880683

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001549643A Pending JP2003519176A (ja) 1999-12-29 2000-12-27 痛みを緩和する方法および組成物

Country Status (12)

Country Link
US (2) US7115661B1 (https=)
EP (2) EP1518553A2 (https=)
JP (1) JP2003519176A (https=)
AT (1) ATE283695T1 (https=)
AU (1) AU782489C (https=)
CA (1) CA2394184A1 (https=)
DE (1) DE60016460T2 (https=)
DK (1) DK1246625T3 (https=)
ES (1) ES2233489T3 (https=)
IL (1) IL150487A0 (https=)
PT (1) PT1246625E (https=)
WO (1) WO2001049275A2 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050137191A1 (en) * 1996-06-04 2005-06-23 Thatcher Gregory R. Nitrate esters and their use for mitigating cellular damage
US20040077702A1 (en) * 2001-09-14 2004-04-22 Wen-Mei Fu Treatment of nuerodegenerative diseases
US7049334B2 (en) * 2001-09-14 2006-05-23 Carlsbad Technology, Inc. Enhancement of learning and memory and treatment of amnesia
AU2003247792B2 (en) 2002-07-03 2009-09-24 Nicox S.A. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
US7244753B2 (en) 2002-07-29 2007-07-17 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
JP2005089457A (ja) * 2003-09-03 2005-04-07 Yung Shin Pharmaceutical Industry Co Ltd 骨成長を促進するまたは骨吸収を阻害するための薬剤組成物
US7968575B2 (en) 2004-05-05 2011-06-28 Renopharm Ltd. Nitric oxide donors and uses thereof
US7498445B2 (en) 2004-05-05 2009-03-03 Renopharm Ltd. Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof
US7189750B2 (en) * 2004-05-05 2007-03-13 Renopharm Ltd. Thiazole-based nitric oxide donors having at least two thiazole moieties and uses thereof
US8134010B2 (en) 2004-05-05 2012-03-13 Renopharm Ltd. Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof
EP1753734A1 (en) 2004-05-05 2007-02-21 Renopharm Ltd. Nitric oxide donors and uses thereof
KR20070053214A (ko) 2004-08-26 2007-05-23 니콜라스 피라말 인디아 리미티드 신규 생분해성 링커를 함유하는 프로드럭
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
CA2580627A1 (en) * 2004-09-17 2006-03-23 Queen's University At Kingston Nitrate esters and their use for mitigating cellular damage
WO2009044902A1 (ja) 2007-10-05 2009-04-09 Kyushu Institute Of Technology 誘電泳動装置および方法
WO2009152071A1 (en) * 2008-06-09 2009-12-17 Vanderbilt University Unnatural dispyrin analogues, preparation and uses thereof
US20100016446A1 (en) * 2008-07-21 2010-01-21 Sylvia Gonda Stable water-based topical pharmaceutical creams and methods of making and using same
US7807716B2 (en) * 2008-09-24 2010-10-05 Oral Delivery Technology Ltd. Nitric oxide amino acid ester compound, compositions for increasing nitric oxide levels and method of use
US8957086B2 (en) * 2010-05-05 2015-02-17 The Board Of Trustees Of The University Of Illinois Compounds and methods of treating brain disorders
WO2014013338A2 (en) * 2012-07-16 2014-01-23 Sgc Pharma, Inc. Compounds for the treatment of alzheimer's disease
WO2014039042A1 (en) 2012-09-06 2014-03-13 Northeastern University Novel cannabinergic compounds and uses thereof
US11964956B2 (en) 2012-09-06 2024-04-23 Northeastern University Cannabinergic compounds and uses thereof
WO2014134127A1 (en) * 2013-02-26 2014-09-04 Northeastern University Cannabinergic nitrate esters and related analogs
JP2018526448A (ja) 2015-09-07 2018-09-13 浙江華海薬業股▲フン▼有限公司 一酸化窒素を放出可能なプロドラッグ分子

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
GB1376892A (en) 1970-11-12 1974-12-11 Glaxo Lab Ltd 2beta-substituted-3alpha-hydroxysteroids and their esters
DE3443998A1 (de) 1984-12-01 1986-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
JPS62205052A (ja) 1986-03-05 1987-09-09 Terumo Corp 硝酸エステル誘導体およびこれを含有する血管拡張剤
US5428061A (en) 1988-09-15 1995-06-27 Schwarz Pharma Ag Organic nitrates and method for their preparation
NL8802276A (nl) 1988-09-15 1990-04-02 Cedona Pharm Bv Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat.
US5284872A (en) 1989-09-12 1994-02-08 Schwarz Pharma Ag Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
DE4321306A1 (de) 1993-06-26 1995-01-05 Sanol Arznei Schwarz Gmbh Disulfide
EP0722434B1 (en) 1993-10-06 1998-07-29 Nicox S.A. Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
JP3276762B2 (ja) 1993-12-28 2002-04-22 日本臓器製薬株式会社 イソキノリン誘導体を含有する医薬組成物
WO1995030641A1 (en) 1994-05-10 1995-11-16 Nicox S.A. Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities
JP3211892B2 (ja) 1994-05-27 2001-09-25 セイジィ ファーマスーティカルス インコーポレーテッド 肛門疾患を治療する窒素酸化物供与体及び方法
TW458776B (en) * 1995-08-15 2001-10-11 Chugai Pharmaceutical Co Ltd Pharmaceutical composition for the treatment of anxiety neurosis
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
US5807847A (en) 1996-06-04 1998-09-15 Queen's University At Kingston Nitrate esters
US6310052B1 (en) 1996-06-04 2001-10-30 Queen's University At Kingston Nitrate esters and their use for neurological conditions
FR2757159B1 (fr) 1996-12-12 1999-12-17 Hoechst Marion Roussel Inc Nouveaux derives nitres analgesiques, anti-inflammatoires et anti-thrombotiques, leur procede de preparation, leur application comme medicaments
IL120531A (en) 1997-03-26 2006-12-31 Yissum Res Dev Co Nitric oxide donors and pharmaceutical compositions containing them

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