JP2003518138A5 - - Google Patents

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Publication number
JP2003518138A5
JP2003518138A5 JP2001547554A JP2001547554A JP2003518138A5 JP 2003518138 A5 JP2003518138 A5 JP 2003518138A5 JP 2001547554 A JP2001547554 A JP 2001547554A JP 2001547554 A JP2001547554 A JP 2001547554A JP 2003518138 A5 JP2003518138 A5 JP 2003518138A5
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JP
Japan
Prior art keywords
ligand
cells
receptor
domain
different
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JP2001547554A
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English (en)
Japanese (ja)
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JP2003518138A (ja
JP4777570B2 (ja
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Priority claimed from US09/721,908 external-priority patent/US6699677B1/en
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Publication of JP2003518138A publication Critical patent/JP2003518138A/ja
Publication of JP2003518138A5 publication Critical patent/JP2003518138A5/ja
Application granted granted Critical
Publication of JP4777570B2 publication Critical patent/JP4777570B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2001547554A 1999-12-20 2000-12-18 テザード・リガンド及び使用方法 Expired - Fee Related JP4777570B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US17297999P 1999-12-20 1999-12-20
US60/172,979 1999-12-20
US18662600P 2000-03-03 2000-03-03
US60/186,626 2000-03-03
US09/721,908 US6699677B1 (en) 1999-12-20 2000-11-24 Tethered ligands and methods of use
US09/721,908 2000-11-24
PCT/US2000/034503 WO2001046698A2 (en) 1999-12-20 2000-12-18 Tethered ligands and methods of use

Publications (3)

Publication Number Publication Date
JP2003518138A JP2003518138A (ja) 2003-06-03
JP2003518138A5 true JP2003518138A5 (https=) 2008-02-28
JP4777570B2 JP4777570B2 (ja) 2011-09-21

Family

ID=27390216

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001547554A Expired - Fee Related JP4777570B2 (ja) 1999-12-20 2000-12-18 テザード・リガンド及び使用方法

Country Status (9)

Country Link
US (1) US6699677B1 (https=)
EP (1) EP1247103B1 (https=)
JP (1) JP4777570B2 (https=)
AT (1) ATE405838T1 (https=)
AU (1) AU2440001A (https=)
CA (1) CA2390690C (https=)
DE (1) DE60040019D1 (https=)
ES (1) ES2311485T3 (https=)
WO (1) WO2001046698A2 (https=)

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Publication number Priority date Publication date Assignee Title
USRE39849E1 (en) 1999-10-12 2007-09-18 Chemocentryx, Inc. Methods for identifying modulators of CCX CKR activity
US6998239B1 (en) * 1999-10-12 2006-02-14 Chemocentryx, Inc. Method for identifying a modulator of the binding of CCX CKR polypeptide to a chemokine
US6780602B2 (en) * 2001-11-01 2004-08-24 Microbiosystems, Limited Partnership Taxonomic identification of pathogenic microorganisms and their toxic proteins
US7413866B2 (en) * 2001-11-30 2008-08-19 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
US7504364B2 (en) 2002-03-01 2009-03-17 Receptors Llc Methods of making arrays and artificial receptors
EP1511850A4 (en) * 2002-06-10 2006-06-07 Metabolex Inc METHODS OF TREATING AND DIAGNOSING DIABETES USING MODULATORS OF CX3CR1
WO2005003326A2 (en) 2003-03-28 2005-01-13 Receptors Llc. Artificial receptors including reversibly immobilized building blocks and methods
US7469076B2 (en) 2003-09-03 2008-12-23 Receptors Llc Sensors employing combinatorial artificial receptors
US20040115634A1 (en) * 2002-12-11 2004-06-17 Isis Pharmaceuticals, Inc. Modulation of stat 6 expression
US7981694B2 (en) * 2003-01-28 2011-07-19 The Regents Of The University Of California Solid phase isolation of proteins, nucleic acids and other macromolecules
GB0306428D0 (en) * 2003-03-20 2003-04-23 Oxagen Ltd Receptor proteins
EP1656092B1 (en) * 2003-08-12 2008-07-23 Philips Intellectual Property & Standards GmbH Closure device for a container
JP2007513337A (ja) * 2003-11-19 2007-05-24 サトリス， インコーポレイテッド アルツハイマー病の診断方法、層化方法およびモニタリング方法
US20060094064A1 (en) * 2003-11-19 2006-05-04 Sandip Ray Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids
EP1789797A1 (en) * 2004-09-03 2007-05-30 Receptors LLC Combinatorial artifical receptors including tether building blocks
WO2006029383A2 (en) 2004-09-11 2006-03-16 Receptors Llc Combinatorial artificial receptors including peptide building blocks
US7585968B2 (en) 2005-03-28 2009-09-08 Isis Pharmaceuticals, Inc. Compositions and their uses directed to thymus and activation-regulated chemokine (TARC)
US20060258610A1 (en) 2005-05-12 2006-11-16 Isis Pharmaceuticals, Inc. Modulation of STAT 6 expression for the treatment of airway hyperresponsiveness
WO2007005715A2 (en) * 2005-07-01 2007-01-11 Inhibtex, Inc. Staphylococcal antibodies which cross-react with fungal antigens
CN101622274A (zh) 2006-12-12 2010-01-06 比奥雷克西斯药物公司 转铁蛋白融合蛋白库
US8846639B2 (en) * 2008-04-04 2014-09-30 Isis Pharmaceutical, Inc. Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity
US20110202284A1 (en) * 2010-02-10 2011-08-18 Mcreynolds Cristopher Novel groups of biomarkers for diagnosing alzheimer's disease
US9163094B2 (en) 2011-09-27 2015-10-20 Massachusetts Institute Of Technology Light-activated fusion proteins and uses therefor
EP2892560B1 (en) 2012-09-06 2019-07-03 Adelaide Research&Innovation Pty Ltd Methods and products for preventing and/or treating metastatic cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6393994A (en) 1993-02-19 1994-09-14 Arris Pharmaceutical Corporation Thin film hpmp matrix systems and methods for constructing and displaying ligands
JPH07147987A (ja) 1993-05-28 1995-06-13 Wisconsin Alumni Res Found ユビキチン接合性酵素（ｅ２）融合タンパク質
US5763199A (en) 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay
US5817527A (en) 1995-11-06 1998-10-06 Chiron Diagnostics Corporation Conjugation of ligand to immobilized protein in organic solvent
EP0876487B1 (en) 1996-01-24 2008-03-12 Schering Corporation Mammalian cx3c chemokine genes
AU7164998A (en) 1997-04-28 1998-11-24 B-E Safe, Inc. Taxonomic identification of microorganisms, proteins and peptides involved in vertebrate disease states

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