ES2311485T3 - Ligandos anclados y procedimientos de utilizacion. - Google Patents
Ligandos anclados y procedimientos de utilizacion. Download PDFInfo
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- ES2311485T3 ES2311485T3 ES00988164T ES00988164T ES2311485T3 ES 2311485 T3 ES2311485 T3 ES 2311485T3 ES 00988164 T ES00988164 T ES 00988164T ES 00988164 T ES00988164 T ES 00988164T ES 2311485 T3 ES2311485 T3 ES 2311485T3
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Classifications
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
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- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17297999P | 1999-12-20 | 1999-12-20 | |
| US172979P | 1999-12-20 | ||
| US18662600P | 2000-03-03 | 2000-03-03 | |
| US186626P | 2000-03-03 | ||
| US09/721,908 US6699677B1 (en) | 1999-12-20 | 2000-11-24 | Tethered ligands and methods of use |
| US721908 | 2000-11-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2311485T3 true ES2311485T3 (es) | 2009-02-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00988164T Expired - Lifetime ES2311485T3 (es) | 1999-12-20 | 2000-12-18 | Ligandos anclados y procedimientos de utilizacion. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6699677B1 (https=) |
| EP (1) | EP1247103B1 (https=) |
| JP (1) | JP4777570B2 (https=) |
| AT (1) | ATE405838T1 (https=) |
| AU (1) | AU2440001A (https=) |
| CA (1) | CA2390690C (https=) |
| DE (1) | DE60040019D1 (https=) |
| ES (1) | ES2311485T3 (https=) |
| WO (1) | WO2001046698A2 (https=) |
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| USRE39849E1 (en) | 1999-10-12 | 2007-09-18 | Chemocentryx, Inc. | Methods for identifying modulators of CCX CKR activity |
| US6998239B1 (en) * | 1999-10-12 | 2006-02-14 | Chemocentryx, Inc. | Method for identifying a modulator of the binding of CCX CKR polypeptide to a chemokine |
| US6780602B2 (en) * | 2001-11-01 | 2004-08-24 | Microbiosystems, Limited Partnership | Taxonomic identification of pathogenic microorganisms and their toxic proteins |
| US7413866B2 (en) * | 2001-11-30 | 2008-08-19 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7504364B2 (en) | 2002-03-01 | 2009-03-17 | Receptors Llc | Methods of making arrays and artificial receptors |
| EP1511850A4 (en) * | 2002-06-10 | 2006-06-07 | Metabolex Inc | METHODS OF TREATING AND DIAGNOSING DIABETES USING MODULATORS OF CX3CR1 |
| WO2005003326A2 (en) | 2003-03-28 | 2005-01-13 | Receptors Llc. | Artificial receptors including reversibly immobilized building blocks and methods |
| US7469076B2 (en) | 2003-09-03 | 2008-12-23 | Receptors Llc | Sensors employing combinatorial artificial receptors |
| US20040115634A1 (en) * | 2002-12-11 | 2004-06-17 | Isis Pharmaceuticals, Inc. | Modulation of stat 6 expression |
| US7981694B2 (en) * | 2003-01-28 | 2011-07-19 | The Regents Of The University Of California | Solid phase isolation of proteins, nucleic acids and other macromolecules |
| GB0306428D0 (en) * | 2003-03-20 | 2003-04-23 | Oxagen Ltd | Receptor proteins |
| EP1656092B1 (en) * | 2003-08-12 | 2008-07-23 | Philips Intellectual Property & Standards GmbH | Closure device for a container |
| JP2007513337A (ja) * | 2003-11-19 | 2007-05-24 | サトリス， インコーポレイテッド | アルツハイマー病の診断方法、層化方法およびモニタリング方法 |
| US20060094064A1 (en) * | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| EP1789797A1 (en) * | 2004-09-03 | 2007-05-30 | Receptors LLC | Combinatorial artifical receptors including tether building blocks |
| WO2006029383A2 (en) | 2004-09-11 | 2006-03-16 | Receptors Llc | Combinatorial artificial receptors including peptide building blocks |
| US7585968B2 (en) | 2005-03-28 | 2009-09-08 | Isis Pharmaceuticals, Inc. | Compositions and their uses directed to thymus and activation-regulated chemokine (TARC) |
| US20060258610A1 (en) | 2005-05-12 | 2006-11-16 | Isis Pharmaceuticals, Inc. | Modulation of STAT 6 expression for the treatment of airway hyperresponsiveness |
| WO2007005715A2 (en) * | 2005-07-01 | 2007-01-11 | Inhibtex, Inc. | Staphylococcal antibodies which cross-react with fungal antigens |
| CN101622274A (zh) | 2006-12-12 | 2010-01-06 | 比奥雷克西斯药物公司 | 转铁蛋白融合蛋白库 |
| US8846639B2 (en) * | 2008-04-04 | 2014-09-30 | Isis Pharmaceutical, Inc. | Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity |
| US20110202284A1 (en) * | 2010-02-10 | 2011-08-18 | Mcreynolds Cristopher | Novel groups of biomarkers for diagnosing alzheimer's disease |
| US9163094B2 (en) | 2011-09-27 | 2015-10-20 | Massachusetts Institute Of Technology | Light-activated fusion proteins and uses therefor |
| EP2892560B1 (en) | 2012-09-06 | 2019-07-03 | Adelaide Research&Innovation Pty Ltd | Methods and products for preventing and/or treating metastatic cancer |
Family Cites Families (6)
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|---|---|---|---|---|
| AU6393994A (en) | 1993-02-19 | 1994-09-14 | Arris Pharmaceutical Corporation | Thin film hpmp matrix systems and methods for constructing and displaying ligands |
| JPH07147987A (ja) | 1993-05-28 | 1995-06-13 | Wisconsin Alumni Res Found | ユビキチン接合性酵素（ｅ２）融合タンパク質 |
| US5763199A (en) | 1994-09-29 | 1998-06-09 | Mount Sinai School Of Medicine Of The City University Of New York | Platelet blockade assay |
| US5817527A (en) | 1995-11-06 | 1998-10-06 | Chiron Diagnostics Corporation | Conjugation of ligand to immobilized protein in organic solvent |
| EP0876487B1 (en) | 1996-01-24 | 2008-03-12 | Schering Corporation | Mammalian cx3c chemokine genes |
| AU7164998A (en) | 1997-04-28 | 1998-11-24 | B-E Safe, Inc. | Taxonomic identification of microorganisms, proteins and peptides involved in vertebrate disease states |
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2000
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- 2000-12-18 DE DE60040019T patent/DE60040019D1/de not_active Expired - Lifetime
- 2000-12-18 AT AT00988164T patent/ATE405838T1/de not_active IP Right Cessation
- 2000-12-18 CA CA2390690A patent/CA2390690C/en not_active Expired - Fee Related
- 2000-12-18 AU AU24400/01A patent/AU2440001A/en not_active Abandoned
- 2000-12-18 ES ES00988164T patent/ES2311485T3/es not_active Expired - Lifetime
- 2000-12-18 JP JP2001547554A patent/JP4777570B2/ja not_active Expired - Fee Related
- 2000-12-18 EP EP00988164A patent/EP1247103B1/en not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1247103A2 (en) | 2002-10-09 |
| JP2003518138A (ja) | 2003-06-03 |
| US6699677B1 (en) | 2004-03-02 |
| EP1247103B1 (en) | 2008-08-20 |
| JP4777570B2 (ja) | 2011-09-21 |
| WO2001046698A3 (en) | 2002-02-21 |
| DE60040019D1 (de) | 2008-10-02 |
| AU2440001A (en) | 2001-07-03 |
| WO2001046698A2 (en) | 2001-06-28 |
| CA2390690A1 (en) | 2001-06-28 |
| ATE405838T1 (de) | 2008-09-15 |
| CA2390690C (en) | 2010-08-10 |
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