JP2003514576A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003514576A5 JP2003514576A5 JP2001540121A JP2001540121A JP2003514576A5 JP 2003514576 A5 JP2003514576 A5 JP 2003514576A5 JP 2001540121 A JP2001540121 A JP 2001540121A JP 2001540121 A JP2001540121 A JP 2001540121A JP 2003514576 A5 JP2003514576 A5 JP 2003514576A5
- Authority
- JP
- Japan
- Prior art keywords
- hcv
- virus
- immunogenic
- particle
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16722499P | 1999-11-24 | 1999-11-24 | |
| US60/167,224 | 1999-11-24 | ||
| PCT/US2000/032249 WO2001038358A2 (en) | 1999-11-24 | 2000-11-22 | Hbv/hcv virus-like particle |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003514576A JP2003514576A (ja) | 2003-04-22 |
| JP2003514576A5 true JP2003514576A5 (https=) | 2008-01-10 |
| JP4647870B2 JP4647870B2 (ja) | 2011-03-09 |
Family
ID=22606465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001540121A Expired - Lifetime JP4647870B2 (ja) | 1999-11-24 | 2000-11-22 | Hbv/hcvウイルス様粒子 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1233783B9 (https=) |
| JP (1) | JP4647870B2 (https=) |
| AT (1) | ATE290399T1 (https=) |
| AU (1) | AU1928201A (https=) |
| CA (1) | CA2392527C (https=) |
| DE (2) | DE60018601D1 (https=) |
| ES (1) | ES2430368T3 (https=) |
| WO (1) | WO2001038358A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60234375D1 (de) | 2001-09-14 | 2009-12-24 | Cytos Biotechnology Ag | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| CN100497604C (zh) * | 2002-02-07 | 2009-06-10 | 墨尔本保健公司 | 对核苷类似物具有改变的敏感性的病毒变体及其应用 |
| DE10218129A1 (de) * | 2002-04-23 | 2003-11-20 | Univ Ruprecht Karls Heidelberg | Genetischer Impfstoff gegen RNA-Virus-Infektionen |
| US20060240039A1 (en) * | 2003-06-13 | 2006-10-26 | Isis Innovation Limited | Vaccines |
| CA2636139A1 (en) | 2005-12-14 | 2007-06-21 | Cytos Biotechnology Ag | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
| US8541559B2 (en) | 2006-06-12 | 2013-09-24 | Cytos Biotechnology Ag | Process for producing aggregated oligonucleotides |
| US20080166785A1 (en) * | 2006-08-16 | 2008-07-10 | Monica Sala-Schaeffer | Polynucleotides allowing the expression and secretion of recombinant HBsAg virus-like particles containing a foreign peptide, their production and use |
| US8586728B2 (en) | 2006-12-12 | 2013-11-19 | Cytos Biotechnology Ag | Oligonucleotides containing high concentrations of guanine monomers |
| FR2932388B1 (fr) * | 2008-06-17 | 2013-03-29 | Univ Rabelais Francois | Nouvelles proteines de fusion et leur application pour la preparation de vaccins contre l'hepatite c |
| US9238679B2 (en) * | 2011-02-11 | 2016-01-19 | The Trustees Of The University Of Pennslyvania | Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same |
| JP2014212722A (ja) * | 2013-04-24 | 2014-11-17 | 学校法人加計学園 | 八面体構造を有するb型肝炎ウイルス様粒子結晶 |
| US11021692B2 (en) | 2017-12-19 | 2021-06-01 | Janssen Sciences Ireland Unlimited Company | Hepatitis B virus (HBV) vaccines and uses thereof |
| TW202245809A (zh) * | 2020-12-18 | 2022-12-01 | 美商詹森藥物公司 | 用於治療b型肝炎病毒感染之組合療法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5098704A (en) * | 1984-06-18 | 1992-03-24 | Chiron Corporation | Hepatitis surface antigen particle vaccine |
| FR2581394B1 (fr) * | 1985-05-02 | 1988-08-05 | Grp Genie Genetique | Particules ayant les proprietes immunogenes de l'antigene hbs et portant un site antigenique etranger aux epitopes portes par l'antigene hbs, vecteurs et cellules animales pour la production de telles particules et compositions contenant de telles particules pour la production de vaccins mixtes |
| KR970010787A (ko) * | 1995-08-14 | 1997-03-27 | 성재갑 | B형 간염 바이러스 표면항원과 c형 간염 바이러스 외피 단백질의 융합 단백질 및 이를 포함하는 혼합 백신 |
-
2000
- 2000-11-22 EP EP00982225A patent/EP1233783B9/en not_active Expired - Lifetime
- 2000-11-22 AT AT00982225T patent/ATE290399T1/de active
- 2000-11-22 JP JP2001540121A patent/JP4647870B2/ja not_active Expired - Lifetime
- 2000-11-22 DE DE60018601A patent/DE60018601D1/de not_active Expired - Lifetime
- 2000-11-22 DE DE60018601T patent/DE60018601T4/de not_active Expired - Lifetime
- 2000-11-22 CA CA2392527A patent/CA2392527C/en not_active Expired - Lifetime
- 2000-11-22 ES ES04078119T patent/ES2430368T3/es not_active Expired - Lifetime
- 2000-11-22 AU AU19282/01A patent/AU1928201A/en not_active Abandoned
- 2000-11-22 WO PCT/US2000/032249 patent/WO2001038358A2/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Lazdina et al. | Priming of cytotoxic T cell responses to exogenous hepatitis B virus core antigen is B cell dependent | |
| ES2213754T3 (es) | Particulas quimericas de tipo papilomavirus. | |
| Clarke et al. | Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein | |
| EP1037917B1 (en) | Recombinant nodavirus compositions and methods | |
| JP2003514576A5 (https=) | ||
| CA2405438A1 (en) | Hepatitis b core antigen fusion proteins | |
| Wizemann et al. | Purification of E. coli-expressed HIS-tagged hepatitis B core antigen by Ni2+-chelate affinity chromatography | |
| JP2006523189A5 (https=) | ||
| Ulrich et al. | New chimaeric hepatitis B virus core particles carrying hantavirus (serotype Puumala) epitopes: immunogenicity and protection against virus challenge | |
| JP2002510494A5 (https=) | ||
| JPS63196293A (ja) | 融合蛋白 | |
| Sominskaya et al. | A VLP library of C-terminally truncated Hepatitis B core proteins: correlation of RNA encapsidation with a Th1/Th2 switch in the immune responses of mice | |
| Beames et al. | Carboxy-terminal truncations of the HBV core protein affect capsid formation and the apparent size of encapsidated HBV RNA | |
| JP2008074867A (ja) | ペプチドリガンドを介して結合された複数の免疫原性成分を有するhbvコア抗原粒子 | |
| Koletzki et al. | HBV core particles allow the insertion and surface exposure of the entire potentially protective region of Puumala hantavirus nucleocapsid protein | |
| EP1780285A1 (en) | Improved virus like particles (VLP) based on the small envelope protein of hepatitis B virus (HBsAg-S) | |
| JPH0327400A (ja) | B型肝炎ウイルスコア抗原粒子 | |
| Pumpens et al. | Evaluation of HBs, HBc, and frCP virus-like particles for expression of human papillomavirus 16 E7 oncoprotein epitopes | |
| Freivalds et al. | Assembly of bacteriophage Qβ virus-like particles in yeast Saccharomyces cerevisiae and Pichia pastoris | |
| JP2001019643A (ja) | 慢性ウイルス性肝臓病に対する治療薬として用いる組成物 | |
| Mihailova et al. | Recombinant virus-like particles as a carrier of B-and T-cell epitopes of hepatitis C virus (HCV) | |
| JP2004501646A5 (https=) | ||
| Borisova et al. | Spatial structure and insertion capacity of immunodominant region of hepatitis B core antigen | |
| JP5656832B2 (ja) | 新規な融合タンパク質及びc型肝炎ワクチンの製造のためのその使用 | |
| CN101036784B (zh) | 一种乙型肝炎治疗性细胞毒性t细胞表位疫苗及其制备方法 |