JP2003510037A5 - - Google Patents

Download PDF

Info

Publication number
JP2003510037A5
JP2003510037A5 JP2001522272A JP2001522272A JP2003510037A5 JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5 JP 2001522272 A JP2001522272 A JP 2001522272A JP 2001522272 A JP2001522272 A JP 2001522272A JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5
Authority
JP
Japan
Prior art keywords
seq
polypeptide
nucleic acid
sequence
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001522272A
Other languages
English (en)
Japanese (ja)
Other versions
JP4339542B2 (ja
JP2003510037A (ja
Filing date
Publication date
Priority claimed from US09/393,634 external-priority patent/US6558910B2/en
Application filed filed Critical
Priority claimed from PCT/US2000/024821 external-priority patent/WO2001018050A2/en
Publication of JP2003510037A publication Critical patent/JP2003510037A/ja
Publication of JP2003510037A5 publication Critical patent/JP2003510037A5/ja
Application granted granted Critical
Publication of JP4339542B2 publication Critical patent/JP4339542B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2001522272A 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー Expired - Fee Related JP4339542B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/393,634 1999-09-10
US09/393,634 US6558910B2 (en) 1999-09-10 1999-09-10 SF, a novel family of taste receptors
US09/510,332 US7244584B2 (en) 1999-09-10 2000-02-22 T2R, a novel family of taste receptors
US09/510,332 2000-02-22
PCT/US2000/024821 WO2001018050A2 (en) 1999-09-10 2000-09-08 T2r taste receptor family

Publications (3)

Publication Number Publication Date
JP2003510037A JP2003510037A (ja) 2003-03-18
JP2003510037A5 true JP2003510037A5 (https=) 2007-09-06
JP4339542B2 JP4339542B2 (ja) 2009-10-07

Family

ID=27014384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001522272A Expired - Fee Related JP4339542B2 (ja) 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー

Country Status (10)

Country Link
US (8) US7465550B2 (https=)
EP (1) EP1214343A2 (https=)
JP (1) JP4339542B2 (https=)
CN (1) CN1289525C (https=)
AU (2) AU773600B2 (https=)
CA (1) CA2384777A1 (https=)
IL (1) IL148593A0 (https=)
MX (1) MXPA02002538A (https=)
NO (1) NO20021164L (https=)
WO (1) WO2001018050A2 (https=)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
EP1214343A2 (en) 1999-09-10 2002-06-19 The Regents Of The University Of California T2r taste receptor family
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
AU2001251258B2 (en) 2000-04-07 2008-06-05 Senomyx, Inc. T2r taste receptors and genes encoding same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US20080244761A1 (en) 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7883856B2 (en) 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US8030008B2 (en) 2001-04-05 2011-10-04 Senomyx, Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
AU2002326315B2 (en) 2001-06-26 2007-07-05 Senomyx, Inc. T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
CA2452337A1 (en) * 2001-07-10 2003-01-23 Senomyx, Inc. Use of specific t2r taste receptors to identify compounds that block bitter taste
AU2002326429B2 (en) * 2001-07-20 2007-09-20 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Phenylthiocarbamide (PTC) taste receptor
US20070059688A1 (en) * 2001-10-12 2007-03-15 Rozengurt Juan E Gastrointestinal chemosensory receptors
WO2004011617A2 (en) 2002-07-29 2004-02-05 Senomyx, Inc. Identification of a novel bitter taste receptor, t2r76
EP2267129B1 (en) * 2002-09-25 2015-03-25 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Bitter taste receptors
DE60320682T2 (de) 2002-12-18 2009-06-10 Givaudan S.A. Chimäre alpha q-gustducin g-proteine
EP1644528A2 (en) 2003-06-19 2006-04-12 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, the Department of Health and Human Services, Variants of human taste receptor genes
WO2006053771A2 (en) 2004-11-18 2006-05-26 Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts Agonists of bitter taste receptors and uses thereof
MX2007009497A (es) 2005-02-08 2008-01-18 Senomyx Inc Receptores t2r humanos para acetaminofen, ranitidina, estricnina y denatonio, y ensayos relacionados para identificar moduladores de sabor amargo humanos.
US8017336B2 (en) 2005-12-27 2011-09-13 Nihon University Method of examining zinc-deficient taste disturbance by determining expression level of taste receptor genes
JP2009533065A (ja) 2006-04-20 2009-09-17 ジボダン エス エー 味覚物質同定のための機能的方法
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
WO2007121604A2 (en) 2006-04-20 2007-11-01 Givaudan Sa Method relating to sweetness enhancement
WO2008030429A2 (en) * 2006-09-05 2008-03-13 Senomyx, Inc. Novel haplotype of human t2r receptor ht2r50 and its use in assays for identifying human bitter taste modulators
WO2008086634A2 (en) 2007-01-18 2008-07-24 Givaudan Sa Chimeric umami taste receptor, nucleic acid encoding it and use thereof
KR20100016044A (ko) 2007-03-30 2010-02-12 지보당 에스아 조절제의 동정 방법
CA2691906A1 (en) * 2007-06-08 2009-01-15 Senomyx, Inc. Identification of trpml3 (mcoln3) as a salty taste receptor and use in assays for identifying taste (salty) modulators and/or therapeutics that modulate sodium transport, absorption or excretion and/or aldosterone and/or vasopressin production or release
KR101558193B1 (ko) 2007-08-21 2015-10-12 세노믹스, 인코포레이티드 인간 ｔ2ｒ 쓴맛 수용체 및 이의 용도
EP2245171A2 (en) * 2008-02-01 2010-11-03 Chromocell Corporation Cell lines and methods for making and using them
EP2567231A1 (en) 2010-05-07 2013-03-13 Givaudan SA Methods to identify modulators of tas2r4s receptors
US20130115624A1 (en) 2010-05-07 2013-05-09 Givaudan S.A. Methods To Identify Modulators
CN103068380A (zh) * 2010-06-17 2013-04-24 加州理工学院 用于调节激素的方法和系统以及相关的方法、剂和组合物
EP2742350B1 (en) 2011-08-08 2019-10-30 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
WO2013159227A1 (en) * 2012-04-25 2013-10-31 University Of Manitoba Bitter taste receptor constitutively active mutants
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
JP6461901B2 (ja) 2013-03-15 2019-01-30 アプライド フード バイオテクノロジー インコーポレーテッド ネコ科苦味受容体及び方法
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
CN105339384A (zh) 2013-05-10 2016-02-17 百事可乐公司 作为鉴别潜在味觉调节剂的模型的细胞
HK1218302A1 (zh) * 2013-05-10 2017-02-10 百事可乐公司 味觉感受器内化试验
EP3104712B1 (en) 2014-02-12 2020-05-06 Firmenich Incorporated Improved process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016178A2 (en) 1992-02-12 1993-08-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Sequences characteristic of human gene transcription product
WO1998013478A2 (en) 1996-09-04 1998-04-02 Mogen International N.V. Antifungal proteins, dna coding therefore, and hosts incorporating same
EP1056764A4 (en) 1998-02-18 2001-08-29 Genetics Inst SECRETED PROTEINS AND POLYNUCLEOTIDES ENCODING SAID PROTEINS
CA2356533C (en) 1998-12-23 2010-07-13 Mount Sinai School Of Medicine Inhibitors of the bitter taste response
EP1214343A2 (en) 1999-09-10 2002-06-19 The Regents Of The University Of California T2r taste receptor family
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors

Similar Documents

Publication Publication Date Title
JP2003510037A5 (https=)
CA2335318A1 (en) Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction
JP2009201525A5 (https=)
AU660950B2 (en) Cell-free receptor binding assays, the production and use thereof
Chang et al. Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases
Hsu et al. Artificial mutations and natural variations in the CD46 molecules from human and monkey cells define regions important for measles virus binding
US5237051A (en) Purified enterotoxin receptor protein
Koizumi et al. Taste-modifying sweet protein, neoculin, is received at human T1R3 amino terminal domain
CA2452716A1 (en) Mammalian sweet and amino acid heterodimeric taste receptors
Lodh et al. Voltage-gated calcium channels of Paramecium cilia
RU2016149596A (ru) Новые полипептиды со специфическим связыванием и пути их применения
JP2010522541A5 (https=)
WO2002036622A2 (en) GαqPROETIN VARIANTS AND THEIR USE IN THE ANALYSIS AND DISCOVERY OF AGONISTS AND ANTAGONISTS OF CHEMOSENSORY RECEPTORS
JP2007507544A5 (https=)
Hamm et al. Loop I of U1 small nuclear RNA is the only essential RNA sequence for binding of specific U1 small nuclear ribonucleoprotein particle proteins
CN102186976B (zh) 修饰型生物素结合蛋白
JPWO2020027010A5 (https=)
JPH1066585A5 (https=)
EP0793721A1 (fr) Peptides capables de se lier au domaine sh3 de la proteine gap, sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation
JP2003527844A5 (https=)
JP2006502738A5 (https=)
JP2009517015A5 (https=)
Lang Purification and characterization of subforms of the guanine‐nucleotide‐binding proteins Gαi and Gαo
JP2003514549A5 (https=)
CN108276488A (zh) 一种鸡髓样细胞触发受体b2多克隆抗体及其制备方法和应用