JP2003510037A5 - - Google Patents

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Publication number
JP2003510037A5
JP2003510037A5 JP2001522272A JP2001522272A JP2003510037A5 JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5 JP 2001522272 A JP2001522272 A JP 2001522272A JP 2001522272 A JP2001522272 A JP 2001522272A JP 2003510037 A5 JP2003510037 A5 JP 2003510037A5
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JP
Japan
Prior art keywords
seq
polypeptide
nucleic acid
sequence
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001522272A
Other languages
English (en)
Japanese (ja)
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JP2003510037A (ja
JP4339542B2 (ja
Filing date
Publication date
Priority claimed from US09/393,634 external-priority patent/US6558910B2/en
Application filed filed Critical
Priority claimed from PCT/US2000/024821 external-priority patent/WO2001018050A2/en
Publication of JP2003510037A publication Critical patent/JP2003510037A/ja
Publication of JP2003510037A5 publication Critical patent/JP2003510037A5/ja
Application granted granted Critical
Publication of JP4339542B2 publication Critical patent/JP4339542B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2001522272A 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー Expired - Fee Related JP4339542B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/393,634 1999-09-10
US09/393,634 US6558910B2 (en) 1999-09-10 1999-09-10 SF, a novel family of taste receptors
US09/510,332 2000-02-22
US09/510,332 US7244584B2 (en) 1999-09-10 2000-02-22 T2R, a novel family of taste receptors
PCT/US2000/024821 WO2001018050A2 (en) 1999-09-10 2000-09-08 T2r taste receptor family

Publications (3)

Publication Number Publication Date
JP2003510037A JP2003510037A (ja) 2003-03-18
JP2003510037A5 true JP2003510037A5 (cg-RX-API-DMAC7.html) 2007-09-06
JP4339542B2 JP4339542B2 (ja) 2009-10-07

Family

ID=27014384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001522272A Expired - Fee Related JP4339542B2 (ja) 1999-09-10 2000-09-08 Ｔ２ｒ、すなわち味覚受容体の新規ファミリー

Country Status (10)

Country Link
US (8) US7465550B2 (cg-RX-API-DMAC7.html)
EP (1) EP1214343A2 (cg-RX-API-DMAC7.html)
JP (1) JP4339542B2 (cg-RX-API-DMAC7.html)
CN (1) CN1289525C (cg-RX-API-DMAC7.html)
AU (2) AU773600B2 (cg-RX-API-DMAC7.html)
CA (1) CA2384777A1 (cg-RX-API-DMAC7.html)
IL (1) IL148593A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA02002538A (cg-RX-API-DMAC7.html)
NO (1) NO20021164L (cg-RX-API-DMAC7.html)
WO (1) WO2001018050A2 (cg-RX-API-DMAC7.html)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL148593A0 (en) 1999-09-10 2002-09-12 Univ California T2r, a novel family of taste receptors
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
JP2003530098A (ja) * 2000-04-07 2003-10-14 セノミックス、インコーポレイテッド Ｔ２ｒ味覚受容体及びそれをコードする遺伝子
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US20080244761A1 (en) 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7883856B2 (en) 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US8030008B2 (en) 2001-04-05 2011-10-04 Senomyx, Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US7338771B2 (en) * 2001-07-10 2008-03-04 Alexey Pronin Use of specific T2R taste receptors to identify compounds that block bitter taste
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
EP1412750B1 (en) 2001-06-26 2012-05-23 Senomyx, Inc. T1r2-t1r3 hetero-oligomeric sweet taste receptors and cell lines that express said receptors and use thereof for identification of sweet taste compounds
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
WO2003008627A2 (en) * 2001-07-20 2003-01-30 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Phenylthiocarbamide (ptc) taste receptor
US20070059688A1 (en) * 2001-10-12 2007-03-15 Rozengurt Juan E Gastrointestinal chemosensory receptors
IL165669A0 (en) 2002-07-29 2006-01-15 Senomyx Inc Identification of a novel bitter taste receptor t2r76
EP2270154A3 (en) * 2002-09-25 2011-08-10 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Bitter taste receptors
AU2003286069A1 (en) 2002-12-18 2004-07-09 Givaudan Sa Chimeric alpha q-gustducin g-proteins
EP1644528A2 (en) * 2003-06-19 2006-04-12 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, the Department of Health and Human Services, Variants of human taste receptor genes
US7829299B2 (en) 2004-11-18 2010-11-09 Deutsches Institut fur Ernahrungforschung Potsdam-Rehbrucke Stiftung des Offentlichen Rechts Agonists of bitter taste receptors and uses thereof
JP2008537473A (ja) 2005-02-08 2008-09-18 セノミクス・インコーポレーテッド アセトアミノフェン、ラニチジン、ストリキニーネおよびデナトニウムのｐヒトＴ２Ｒ受容体、ならびにヒト苦味調節剤を同定するための関連アッセイ
JPWO2007074937A1 (ja) 2005-12-27 2009-06-04 学校法人日本大学 亜鉛欠乏性味覚異常検査法
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
EP2995950B1 (en) 2006-04-20 2024-01-17 Givaudan SA Method relating to sweetness enhancement
US8124360B2 (en) 2006-04-20 2012-02-28 Givaudan S.A. Use of a T1R2 nucleic acid sequence to identify tastants
US7811788B2 (en) * 2006-09-05 2010-10-12 Senomyx Inc. Nucleic acid encoding a haplotype of human T2R receptor hT2R50
KR101511394B1 (ko) 2007-01-18 2015-04-10 지보당 에스아 키메라 우마미 미각 수용체, 이를 코딩하는 핵산 및 이의 용도
WO2008119195A1 (en) 2007-03-30 2008-10-09 Givaudan Sa Methods to identify modulators
WO2008153924A2 (en) 2007-06-08 2008-12-18 Senomyx, Inc. Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays
EP2195656A4 (en) 2007-08-21 2011-10-19 Senomyx Inc HUMAN T2R BITTERITY RECEPTORS AND USES THEREOF
CN103525751B (zh) * 2008-02-01 2017-04-12 克罗莫塞尔公司 细胞系以及制备和使用其的方法
US20130123135A1 (en) 2010-05-07 2013-05-16 Jay Patrick Slack Methods To Identify Modulators of TAS2R48 Receptors
US20130115624A1 (en) 2010-05-07 2013-05-09 Givaudan S.A. Methods To Identify Modulators
KR20130112019A (ko) 2010-06-17 2013-10-11 캘리포니아 인스티튜트 오브 테크놀로지 호르몬을 조절하기 위한 방법 및 시스템 및 관련 방법, 작용제 및 조성물
US9128079B2 (en) 2011-08-08 2015-09-08 The Coca-Cola Company Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
WO2013159227A1 (en) * 2012-04-25 2013-10-31 University Of Manitoba Bitter taste receptor constitutively active mutants
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
ES2797547T3 (es) 2013-03-15 2020-12-02 Applied Food Biotech Inc Receptores del sabor amargo felino y métodos.
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
PL2994482T3 (pl) * 2013-05-10 2020-06-01 Pepsico, Inc. Test internalizacji receptora smaku
HK1218301A1 (zh) 2013-05-10 2017-02-10 百事可乐公司 作為鑒別潛在味覺調節劑的模型的細胞
EP3104712B1 (en) 2014-02-12 2020-05-06 Firmenich Incorporated Improved process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016178A2 (en) 1992-02-12 1993-08-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Sequences characteristic of human gene transcription product
EP0939798B1 (en) 1996-09-04 2004-11-17 Syngenta Mogen B.V. Antifungal proteins, dna coding therefore, and hosts incorporating same
EP1056764A4 (en) 1998-02-18 2001-08-29 Genetics Inst SECRETED PROTEINS AND POLYNUCLEOTIDES ENCODING SAID PROTEINS
WO2000038536A2 (en) 1998-12-23 2000-07-06 Mount Sinai School Of Medicine Of New York University Inhibitors of the bitter taste response
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
IL148593A0 (en) 1999-09-10 2002-09-12 Univ California T2r, a novel family of taste receptors

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