JP2003509502A5 - - Google Patents

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Publication number
JP2003509502A5
JP2003509502A5 JP2001524979A JP2001524979A JP2003509502A5 JP 2003509502 A5 JP2003509502 A5 JP 2003509502A5 JP 2001524979 A JP2001524979 A JP 2001524979A JP 2001524979 A JP2001524979 A JP 2001524979A JP 2003509502 A5 JP2003509502 A5 JP 2003509502A5
Authority
JP
Japan
Prior art keywords
carbonylamino
methyl
propyl
isoxazole
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001524979A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003509502A (ja
JP4195561B2 (ja
Filing date
Publication date
Priority claimed from PCT/KR1999/000561 external-priority patent/WO2001021599A1/en
Priority claimed from KR10-1999-0048608A external-priority patent/KR100399361B1/ko
Application filed filed Critical
Priority claimed from PCT/KR2000/001047 external-priority patent/WO2001021600A1/en
Publication of JP2003509502A publication Critical patent/JP2003509502A/ja
Publication of JP2003509502A5 publication Critical patent/JP2003509502A5/ja
Application granted granted Critical
Publication of JP4195561B2 publication Critical patent/JP4195561B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2001524979A 1999-09-17 2000-09-18 カスパーゼインヒビター Expired - Fee Related JP4195561B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/KR1999/000561 WO2001021599A1 (en) 1999-09-17 1999-09-17 Caspase inhibitor
KR99/00561 1999-09-17
KR1999/48608 1999-11-04
KR10-1999-0048608A KR100399361B1 (ko) 1999-11-04 1999-11-04 캐스파제 억제제 함유 치료제 조성물
PCT/KR2000/001047 WO2001021600A1 (en) 1999-09-17 2000-09-18 Caspase inhibitor

Publications (3)

Publication Number Publication Date
JP2003509502A JP2003509502A (ja) 2003-03-11
JP2003509502A5 true JP2003509502A5 (cg-RX-API-DMAC10.html) 2008-10-02
JP4195561B2 JP4195561B2 (ja) 2008-12-10

Family

ID=26634563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001524979A Expired - Fee Related JP4195561B2 (ja) 1999-09-17 2000-09-18 カスパーゼインヒビター

Country Status (8)

Country Link
EP (1) EP1212309B1 (cg-RX-API-DMAC10.html)
JP (1) JP4195561B2 (cg-RX-API-DMAC10.html)
CN (1) CN1137888C (cg-RX-API-DMAC10.html)
AT (1) ATE273705T1 (cg-RX-API-DMAC10.html)
AU (1) AU7322300A (cg-RX-API-DMAC10.html)
CA (1) CA2388564C (cg-RX-API-DMAC10.html)
DE (1) DE60013147T2 (cg-RX-API-DMAC10.html)
WO (1) WO2001021600A1 (cg-RX-API-DMAC10.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100399361B1 (ko) * 1999-11-04 2003-09-26 주식회사 엘지생명과학 캐스파제 억제제 함유 치료제 조성물
US7026111B2 (en) * 2001-10-15 2006-04-11 Beckman Coulter, Inc. Methods and reagents for improved cell-based assays
KR100594544B1 (ko) * 2003-08-27 2006-06-30 주식회사 엘지생명과학 이소옥사졸린 구조를 갖는 캐스파제 저해제
KR100774999B1 (ko) * 2005-02-26 2007-11-09 주식회사 엘지생명과학 이소옥사졸린 유도체 및 그의 제조 방법
EP1746167A1 (en) * 2005-07-20 2007-01-24 Apoxis SA Method for the identification of compounds susceptible to inhibit inflammation
WO2009013293A1 (en) * 2007-07-24 2009-01-29 Novartis Ag Substituted cyclohexanecarboxamides useful as bace inhibitors
KR20090099886A (ko) * 2008-03-18 2009-09-23 주식회사 엘지생명과학 캐스파제 저해제의 프로드럭
TW201919712A (zh) 2017-08-10 2019-06-01 法商塞勒尼斯醫療控股公司 運送子(cargomers)
TWI906428B (zh) * 2020-12-10 2025-12-01 南韓商Ｌｇ化學股份有限公司 酸（Ｂｏｒｏｎｉｃ Ａｃｉｄ）化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ283564B6 (cs) * 1993-11-26 1998-05-13 Pfizer Inc. 3-Aryl-2-isoxazolin-5-hydroxamové kyseliny a farmaceutické prostředky na jejich bázi
JP2818820B2 (ja) * 1993-11-26 1998-10-30 ファイザー・インク． 抗炎症剤としての３−アリール−２−イソオキサゾリン類
AU684887B2 (en) * 1994-03-09 1998-01-08 Pfizer Inc. Isoxazoline compounds as inhibitors of TNF release
BR9712987A (pt) * 1996-10-11 2000-04-18 Warner Lambert Co Inibidores de enzima de conversão de interleucina-1beta de sulfonamida
JPH11180891A (ja) * 1997-12-25 1999-07-06 Dai Ichi Seiyaku Co Ltd 抗細胞死剤
KR100373375B1 (ko) * 1998-04-03 2003-06-12 주식회사 엘지생명과학 인터루킨-1b-컨버팅효소및아포파인/cpp-32에대한저해제
WO2001021599A1 (en) * 1999-09-17 2001-03-29 Lg Chemical Ltd. Caspase inhibitor

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