JP2003508079A - 老年期体細胞からクローン化された動物中の細胞寿命のテロメア回復と延長 - Google Patents
老年期体細胞からクローン化された動物中の細胞寿命のテロメア回復と延長Info
- Publication number
- JP2003508079A JP2003508079A JP2001521771A JP2001521771A JP2003508079A JP 2003508079 A JP2003508079 A JP 2003508079A JP 2001521771 A JP2001521771 A JP 2001521771A JP 2001521771 A JP2001521771 A JP 2001521771A JP 2003508079 A JP2003508079 A JP 2003508079A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- gene
- telomerase
- cloned
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/04—Cells produced using nuclear transfer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Psychology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- AIDS & HIV (AREA)
- Obesity (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15234099P | 1999-09-07 | 1999-09-07 | |
| US60/152,340 | 1999-09-07 | ||
| US17948600P | 2000-02-01 | 2000-02-01 | |
| US60/179,486 | 2000-02-01 | ||
| US52702600A | 2000-03-16 | 2000-03-16 | |
| US09/527,026 | 2000-03-16 | ||
| US52087900A | 2000-04-05 | 2000-04-05 | |
| US09/520,879 | 2000-04-05 | ||
| PCT/US2000/024393 WO2001018236A1 (en) | 1999-09-07 | 2000-09-06 | Telomere restoration and extension of cell life-span in animals cloned from senescent somatic cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003508079A true JP2003508079A (ja) | 2003-03-04 |
| JP2003508079A5 JP2003508079A5 (https=) | 2007-11-01 |
Family
ID=27496015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001521771A Pending JP2003508079A (ja) | 1999-09-07 | 2000-09-06 | 老年期体細胞からクローン化された動物中の細胞寿命のテロメア回復と延長 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1214443A4 (https=) |
| JP (1) | JP2003508079A (https=) |
| CN (1) | CN1377424A (https=) |
| AU (1) | AU7350800A (https=) |
| BR (1) | BR0013844A (https=) |
| CA (1) | CA2383790C (https=) |
| IL (2) | IL148457A0 (https=) |
| MX (1) | MXPA02002443A (https=) |
| NZ (1) | NZ531844A (https=) |
| WO (1) | WO2001018236A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012120486A (ja) * | 2010-12-08 | 2012-06-28 | Kinki Univ | 免疫不全動物を用いた細胞の製法 |
| JP2023099826A (ja) * | 2013-03-15 | 2023-07-13 | エリクサージェン セラピューティクス,インコーポレイティド | ヒト細胞を若返らせるためのzscan4の使用方法 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001018193A1 (en) * | 1999-09-07 | 2001-03-15 | Advanced Cell Technology, Inc. | Method for generating immune-compatible cells and tissues using nuclear transfer techniques |
| US7947457B2 (en) | 2007-01-08 | 2011-05-24 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7709245B2 (en) | 2007-01-08 | 2010-05-04 | The Invention Science Fund I, Llc | Systems for genome selection |
| US8003371B2 (en) | 2007-01-08 | 2011-08-23 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7718418B2 (en) | 2007-01-08 | 2010-05-18 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7709244B2 (en) | 2007-01-08 | 2010-05-04 | The Invention Science Fund I, Llc | Systems for genome selection |
| US8012740B2 (en) | 2007-01-08 | 2011-09-06 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7947455B2 (en) | 2007-01-08 | 2011-05-24 | The Invention Science Fund I, Llc | System for genome selection |
| US7985578B2 (en) | 2007-01-08 | 2011-07-26 | The Invention Science Fund I, Llc | Systems for genome selection |
| US8521440B2 (en) | 2007-01-08 | 2013-08-27 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7648823B2 (en) | 2007-01-08 | 2010-01-19 | Searete Llc | Systems for genome selection |
| US7713728B2 (en) | 2007-01-08 | 2010-05-11 | The Invention Sciencefund I, Llc | Systems for genome selection |
| US20110086424A1 (en) * | 2008-05-06 | 2011-04-14 | Advanced Cell Technology, Inc. | Methods for producing enucleated erythroid cells derived from pluripotent stem cells |
| CN103562376B (zh) * | 2011-04-08 | 2017-12-29 | 国家医疗保健研究所 | 复壮细胞的方法 |
| SG10201907918VA (en) | 2015-03-23 | 2019-10-30 | Astellas Inst For Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| CN112654244B (zh) * | 2018-09-06 | 2023-07-25 | 德克萨斯大学系统董事会 | 端粒酶全酶复合体及其使用方法 |
| EP4525895A1 (en) * | 2022-05-17 | 2025-03-26 | National University of Singapore | Chimeric ovarian follicle-based therapy to treat female infertility |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998039416A1 (en) * | 1997-03-06 | 1998-09-11 | Infigen, Inc. | Method of cloning animals |
| JP2003509028A (ja) * | 1999-09-07 | 2003-03-11 | アドバンスド セル テクノロジー、インコーポレイテッド | 核移植技術を用いた免疫適合性を有する細胞及び組織を産生する方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5489508A (en) * | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
| US5648215A (en) * | 1992-05-13 | 1997-07-15 | Board Of Regents, The University Of Texas System | Telomerase diagnostic methods |
| US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| GB9809178D0 (en) * | 1998-04-29 | 1998-07-01 | Univ Edinburgh | Nuclear reprogramming of somatic cells |
| AU782286B2 (en) * | 1999-06-30 | 2005-07-14 | Advanced Cell Technology, Inc. | Cytoplasmic transfer to de-differentiate recipient cells |
-
2000
- 2000-09-06 CN CN00813712A patent/CN1377424A/zh active Pending
- 2000-09-06 JP JP2001521771A patent/JP2003508079A/ja active Pending
- 2000-09-06 IL IL14845700A patent/IL148457A0/xx unknown
- 2000-09-06 MX MXPA02002443A patent/MXPA02002443A/es not_active Application Discontinuation
- 2000-09-06 AU AU73508/00A patent/AU7350800A/en not_active Abandoned
- 2000-09-06 EP EP00961569A patent/EP1214443A4/en not_active Ceased
- 2000-09-06 WO PCT/US2000/024393 patent/WO2001018236A1/en not_active Ceased
- 2000-09-06 BR BR0013844-4A patent/BR0013844A/pt not_active Application Discontinuation
- 2000-09-06 NZ NZ531844A patent/NZ531844A/en not_active IP Right Cessation
- 2000-09-06 CA CA2383790A patent/CA2383790C/en not_active Expired - Lifetime
-
2002
- 2002-02-28 IL IL148457A patent/IL148457A/en active IP Right Grant
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998039416A1 (en) * | 1997-03-06 | 1998-09-11 | Infigen, Inc. | Method of cloning animals |
| JP2003509028A (ja) * | 1999-09-07 | 2003-03-11 | アドバンスド セル テクノロジー、インコーポレイテッド | 核移植技術を用いた免疫適合性を有する細胞及び組織を産生する方法 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012120486A (ja) * | 2010-12-08 | 2012-06-28 | Kinki Univ | 免疫不全動物を用いた細胞の製法 |
| JP2023099826A (ja) * | 2013-03-15 | 2023-07-13 | エリクサージェン セラピューティクス,インコーポレイティド | ヒト細胞を若返らせるためのzscan4の使用方法 |
| JP7633309B2 (ja) | 2013-03-15 | 2025-02-19 | エリクサージェン セラピューティクス,インコーポレイティド | ヒト細胞を若返らせるためのzscan4の使用方法 |
| JP2025065335A (ja) * | 2013-03-15 | 2025-04-17 | エリクサージェン セラピューティクス,インコーポレイティド | ヒト細胞を若返らせるためのzscan4の使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001018236A1 (en) | 2001-03-15 |
| NZ531844A (en) | 2005-08-26 |
| IL148457A (en) | 2013-01-31 |
| EP1214443A4 (en) | 2003-08-27 |
| CA2383790A1 (en) | 2001-03-15 |
| AU7350800A (en) | 2001-04-10 |
| CN1377424A (zh) | 2002-10-30 |
| CA2383790C (en) | 2016-11-22 |
| MXPA02002443A (es) | 2004-07-16 |
| IL148457A0 (en) | 2002-09-12 |
| BR0013844A (pt) | 2002-05-14 |
| EP1214443A1 (en) | 2002-06-19 |
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