JP2003507025A5 - - Google Patents

Download PDF

Info

Publication number
JP2003507025A5
JP2003507025A5 JP2001516946A JP2001516946A JP2003507025A5 JP 2003507025 A5 JP2003507025 A5 JP 2003507025A5 JP 2001516946 A JP2001516946 A JP 2001516946A JP 2001516946 A JP2001516946 A JP 2001516946A JP 2003507025 A5 JP2003507025 A5 JP 2003507025A5
Authority
JP
Japan
Prior art keywords
primer
sequence
target
hybridizing
label
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001516946A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003507025A (ja
Filing date
Publication date
Priority claimed from US09/376,097 external-priority patent/US6232104B1/en
Application filed filed Critical
Publication of JP2003507025A publication Critical patent/JP2003507025A/ja
Publication of JP2003507025A5 publication Critical patent/JP2003507025A5/ja
Pending legal-status Critical Current

Links

JP2001516946A 1999-08-17 2000-08-15 偶発的ｄｎａ分枝移動の抑制による核酸の相違の検出 Pending JP2003507025A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/376,097 US6232104B1 (en) 1999-08-17 1999-08-17 Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration
US09/376,097 1999-08-17
PCT/US2000/022446 WO2001012859A2 (en) 1999-08-17 2000-08-15 Detection of differences in nucleic acids by inhibition of spontaneous dna branch migration

Publications (2)

Publication Number Publication Date
JP2003507025A JP2003507025A (ja) 2003-02-25
JP2003507025A5 true JP2003507025A5 (enExample) 2007-10-04

Family

ID=23483699

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001516946A Pending JP2003507025A (ja) 1999-08-17 2000-08-15 偶発的ｄｎａ分枝移動の抑制による核酸の相違の検出

Country Status (6)

Country Link
US (1) US6232104B1 (enExample)
EP (1) EP1210457B1 (enExample)
JP (1) JP2003507025A (enExample)
DE (1) DE60033825T2 (enExample)
ES (1) ES2281354T3 (enExample)
WO (1) WO2001012859A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2370232T3 (es) * 2000-05-04 2011-12-13 Siemens Healthcare Diagnostics Products Gmbh Procedimiento para la detección de múltiples analitos.
JP4982921B2 (ja) * 2001-03-05 2012-07-25 ルネサスエレクトロニクス株式会社 半導体装置及びその製造方法
US6878530B2 (en) * 2002-02-07 2005-04-12 Panomics, Inc. Methods for detecting polymorphisms in nucleic acids
GB0310270D0 (en) * 2003-05-03 2003-06-11 Univ Edinburgh Biomolecular devices
US7273762B2 (en) * 2004-11-09 2007-09-25 Freescale Semiconductor, Inc. Microelectromechanical (MEM) device including a spring release bridge and method of making the same
GB0518867D0 (en) * 2005-09-15 2005-10-26 Secretary Trade Ind Brit Microscopy tip
US20140302486A1 (en) * 2011-09-02 2014-10-09 President And Fellows Of Harvard College Systems and methods for detecting biomarkers of interest
SG10201510189WA (en) 2011-10-19 2016-01-28 Nugen Technologies Inc Compositions And Methods For Directional Nucleic Acid Amplification And Sequencing
CN104093890B (zh) 2012-01-26 2016-04-20 纽亘技术公司 用于靶向核酸序列富集和高效文库产生的组合物和方法
ES2905448T3 (es) 2012-05-10 2022-04-08 Massachusetts Gen Hospital Métodos para determinar una secuencia nucleotídica
US9957549B2 (en) 2012-06-18 2018-05-01 Nugen Technologies, Inc. Compositions and methods for negative selection of non-desired nucleic acid sequences
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
EP2738263A1 (en) * 2012-11-30 2014-06-04 Fundacion para la Investigacion del Hospital Clinico de la Comunidad Valenciana Methods for DNA rearrengements analysis
EP2971130A4 (en) 2013-03-15 2016-10-05 Nugen Technologies Inc SEQUENTIAL SEQUENCING
CN105849264B (zh) 2013-11-13 2019-09-27 纽亘技术公司 用于鉴别重复测序读数的组合物和方法
WO2015112974A1 (en) 2014-01-27 2015-07-30 The General Hospital Corporation Methods of preparing nucleic acids for sequencing
US9745614B2 (en) 2014-02-28 2017-08-29 Nugen Technologies, Inc. Reduced representation bisulfite sequencing with diversity adaptors
EP3287528A1 (de) 2016-08-25 2018-02-28 AGCT GmbH Verfahren zur amplifikation von nukleinsäuren und kit zu dessen durchführung
JP6997772B2 (ja) 2016-09-15 2022-01-18 アーチャーディーエックス， エルエルシー 核酸サンプル調製の方法
EP4353830A3 (en) 2016-09-15 2024-07-03 ArcherDX, LLC Methods of nucleic acid sample preparation for analysis of cell-free dna
US12492430B2 (en) 2017-04-11 2025-12-09 Tecan Genomics, Inc. Library quantitation and qualification
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
AU2020218190A1 (en) * 2019-02-04 2021-08-26 Akoya Biosciences, Inc. Analyte detection by selective labeling of biological samples
US12059674B2 (en) 2020-02-03 2024-08-13 Tecan Genomics, Inc. Reagent storage system

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254114A (en) 1984-05-07 1989-05-16 Allied Corporation Displacement polynucleotide assay employing recombination protein and diagnostic kit
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
JP2650159B2 (ja) 1988-02-24 1997-09-03 アクゾ・ノベル・エヌ・ベー 核酸増幅方法
US5622820A (en) 1988-03-10 1997-04-22 City Of Hope Method for amplification and detection of RNA and DNA sequences
EP0433363A4 (en) 1988-09-08 1992-05-06 The Salk Institute For Biological Studies Replicative rna-based amplification detection systems
US5508178A (en) 1989-01-19 1996-04-16 Rose; Samuel Nucleic acid amplification using single primer
US5556750A (en) 1989-05-12 1996-09-17 Duke University Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
US5035996A (en) 1989-06-01 1991-07-30 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5766849A (en) 1989-07-11 1998-06-16 Gen-Probe Incorporated Methods of amplifying nucleic acids using promoter-containing primer sequence
GB8920097D0 (en) 1989-09-06 1989-10-18 Ici Plc Amplification processes
US5187066A (en) 1990-02-14 1993-02-16 Syntex (U.S.A.) Inc. Methods for detecting amphiphilic antigens
CA2037349C (en) 1990-03-26 2008-06-17 James G. Wetmur Branch migration of nucleotides
HU218095B (hu) 1990-05-01 2000-05-28 Amgen Inc. Eljárás átvitt szennyeződések csökkentésére, amplifikációs eljárásokban
US5595891A (en) 1990-07-19 1997-01-21 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
US5525462A (en) 1991-05-02 1996-06-11 Toyo Boseki Kabushiki Kaisha Nucleic acid sequence amplification method, detection method, and reagent kit therefor
DE69213112T2 (de) * 1991-06-20 1997-04-03 Hoffmann La Roche Verbesserte Methoden zur Nukleinsäure-Amplifizierung
US5582981A (en) 1991-08-14 1996-12-10 Gilead Sciences, Inc. Method for identifying an oligonucleotide aptamer specific for a target
EP0543484B1 (en) 1991-08-30 2001-01-31 Research Development Corporation of Japan A method of DNA amplification
DE4213029A1 (de) 1991-09-26 1993-04-01 Boehringer Mannheim Gmbh Verfahren zur spezifischen vervielfaeltigung von nukleins aeuresequenzen
CA2100159C (en) 1991-11-15 2003-01-21 John R. Link Rapid assays for amplification products
US5567583A (en) 1991-12-16 1996-10-22 Biotronics Corporation Methods for reducing non-specific priming in DNA detection
WO1993017127A1 (en) 1992-02-20 1993-09-02 The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University Boomerand dna amplification
FR2690691B1 (fr) 1992-04-29 1999-02-12 Bio Merieux Procede d'amplification d'arn necessitant une seule etape de manipulation.
CA2135073C (en) 1992-05-06 2002-11-19 Daniel L. Kacian Nucleic acid sequence amplification method, composition and kit
DK0653066T3 (da) 1992-07-31 1998-09-23 Dade Behring Marburg Gmbh Fotoaktiverbare kemiluminescerende matricer
US5340728A (en) 1992-12-09 1994-08-23 E. I. Du Pont De Nemours And Company Method for amplification of targeted segments of nucleic acid using nested polymerase chain reaction
US5593840A (en) 1993-01-27 1997-01-14 Oncor, Inc. Amplification of nucleic acid sequences
US5616464A (en) 1994-12-27 1997-04-01 Naxcor Nucleic acid sequence detection employing amplification probes
US5470723A (en) 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
US5422252A (en) * 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
KR100189229B1 (ko) * 1993-07-23 1999-06-01 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 핵산 증폭을 강화하는 방법
AU7551594A (en) 1993-07-29 1995-02-28 MURASHIGE, Kate H. Method for recognition of the nucleotide sequence of a purified dna segment
US5556773A (en) 1993-08-06 1996-09-17 Yourno; Joseph Method and apparatus for nested polymerase chain reaction (PCR) with single closed reaction tubes
US5480783A (en) 1994-03-31 1996-01-02 The Perkin-Elmer Corporation Method for reducing background signals in DNA replication/detection assays
US5580730A (en) 1994-08-19 1996-12-03 Olympus America, Inc. Enzyme digestion method for the detection of amplified DNA
FR2724934B1 (fr) 1994-09-26 1997-01-24 Bio Merieux Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
US5512441A (en) 1994-11-15 1996-04-30 American Health Foundation Quantative method for early detection of mutant alleles and diagnostic kits for carrying out the method
US5710029A (en) 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
FR2737223B1 (fr) * 1995-07-24 1997-09-12 Bio Merieux Procede d'amplification de sequences d'acide nucleique par deplacement, a l'aide d'amorces chimeres
US5681705A (en) 1995-08-28 1997-10-28 Schram; James L. Amplification and detection of mycobacterium avium complex species
US5780231A (en) 1995-11-17 1998-07-14 Lynx Therapeutics, Inc. DNA extension and analysis with rolling primers
US6013439A (en) * 1995-12-22 2000-01-11 Dade Behring Marburg Gmbh Detection of differences in nucleic acids
WO2000043546A2 (en) * 1999-01-19 2000-07-27 Dade Behring Inc. Detection of drug resistant organisms

Similar Documents

Publication Publication Date Title
JP2003507025A5 (enExample)
AU2016252998B2 (en) Amplification with primers of limited nucleotide composition
CN104379763B (zh) 使用包含硫代磷酸酯基的寡核苷酸的聚合酶链式反应检测系统
US6261846B1 (en) Gene amplifying method
AU2022203553B2 (en) Exponential base-greater-than-2 nucleic acid amplification
JP2025026849A (ja) 核酸検出方法
EP0379369A2 (en) Nucleic acid amplification using single primer
AU7691796A (en) A cascade nucleic acid amplification reaction
CN109642251B (zh) 核酸扩增过程中的改进或与核酸扩增过程相关的改进
BRPI0609031B1 (pt) METHODS FOR THE SYNTHESIS OF A NUCLEIC ACID MOLECULE, TO SELECTIVELY AMPLIFY A SEQUENCE OF NUCLEIC ACID TARGETED OF A DNA OR A MIXTURE OF NUCLEIC ACIDS, TO AMPLIFY TWO OR MORE SEQUENCES OF NUCLEOTIDE TARGET SIMULTANEOUSLY, TO SEQUENCE A TARGETED NUCLEIC ACID MOLECULE , To detect a nucleic acid molecule with genetic diversity to detect a target nucleotide sequence in a sample of the nucleic acid and to allow a ring specificity of an oligonucleotide to be determined by a structure of the oligonucleotide and oligonucleotide OF DUAL SPECIFICITY
WO2010030716A1 (en) Detection of nucleic acids by oligonucleotide probes cleaved in presence of endonuclease v
RU2729983C2 (ru) Способ амплификации днк на основе внедрения в цепь
EP1017855B1 (en) Methods of synthesizing polynucleotides by ligation of multiple oligomers
JP2003527866A5 (enExample)
Oberc et al. Nucleic acid amplification test (NAAT) conducted in a microfluidic chip to differentiate between various ginseng species
JP2025507309A (ja) 核酸増幅のための内部対照
KR101096570B1 (ko) 비듬 원인균인 말라세지아 속 효모균 검출용 올리고뉴클레오타이드
EP1200624A2 (en) Multiplexed strand displacement for nucleic acid determinations
US20220002792A1 (en) Accelerated polymerase chain reaction
WO2018009677A1 (en) Fast target enrichment by multiplexed relay pcr with modified bubble primers
JP2025541744A (ja) 核酸検出のための非対称性ヘアピンプローブ
KR20250040124A (ko) 프라이머 형성 회전환 증폭용 프로브를 이용한 식중독균 검출 방법
Yan JUNCTION PROBES-SEQUENCE SPECIFIC DETECTION OF NUCLEIC ACIDS VIA TEMPLATE ENHANCED HYBRIDIZATION PROCESSES