JP2003504377A - ヌクレオシドから得られる新規ないエステルと、その製造方法と、それを含む医薬組成物 - Google Patents

ヌクレオシドから得られる新規ないエステルと、その製造方法と、それを含む医薬組成物

Info

Publication number
JP2003504377A
JP2003504377A JP2001509743A JP2001509743A JP2003504377A JP 2003504377 A JP2003504377 A JP 2003504377A JP 2001509743 A JP2001509743 A JP 2001509743A JP 2001509743 A JP2001509743 A JP 2001509743A JP 2003504377 A JP2003504377 A JP 2003504377A
Authority
JP
Japan
Prior art keywords
group
nucleoside
formula
amino
thymidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001509743A
Other languages
English (en)
Japanese (ja)
Inventor
ブレゲ，パトリック
クロ，ジャン−ルイ
クレルク，ティエリ
サレ，ジャン−ピエール
Original Assignee
ラボラトワール ラファル
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ラボラトワール ラファル filed Critical ラボラトワール ラファル
Publication of JP2003504377A publication Critical patent/JP2003504377A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2001509743A 1999-07-12 2000-07-11 ヌクレオシドから得られる新規ないエステルと、その製造方法と、それを含む医薬組成物 Withdrawn JP2003504377A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9909004A FR2796384A1 (fr) 1999-07-12 1999-07-12 Nouveaux esters derives de nucleosides, leurs procedes de preparation et les compositions pharmaceutiques en renfermant
FR99/09004 1999-07-12
PCT/FR2000/002002 WO2001004134A2 (fr) 1999-07-12 2000-07-11 Nouveaux esters derives de nucleosides, leurs procedes de preparation et les compositions pharmaceutiques en renfermant

Publications (1)

Publication Number Publication Date
JP2003504377A true JP2003504377A (ja) 2003-02-04

Family

ID=9547990

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001509743A Withdrawn JP2003504377A (ja) 1999-07-12 2000-07-11 ヌクレオシドから得られる新規ないエステルと、その製造方法と、それを含む医薬組成物

Country Status (10)

Country Link
JP (1) JP2003504377A (no)
AP (1) AP2002002395A0 (no)
AU (1) AU6452300A (no)
BR (1) BR0012381A (no)
CA (1) CA2374411A1 (no)
FR (1) FR2796384A1 (no)
IL (1) IL147449A0 (no)
NO (1) NO20020129L (no)
PL (1) PL352486A1 (no)
WO (1) WO2001004134A2 (no)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011099443A1 (ja) * 2010-02-15 2011-08-18 日産化学工業株式会社 β－ジヒドロフラン誘導化合物、β－ジヒドロフラン誘導化合物またはβ－テトラヒドロフラン誘導化合物の製造方法、β－グリコシド化合物、β－グリコシド化合物の製造方法、並びに、４'－エチニルｄ４Ｔ及びその類縁化合物の製造方法
US8975394B2 (en) 2010-02-15 2015-03-10 Nissan Chemical Industries, Ltd. Process for preparation of β-glycoside compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0988304T3 (da) * 1997-08-15 2001-08-20 Medivir Ab Nukleosidanaloger såsom antivirale midler omfattende inhibitorer af retroviral revers transkriptase og DNA-polymerasen fra hepatitis B-virus (HBV)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011099443A1 (ja) * 2010-02-15 2011-08-18 日産化学工業株式会社 β－ジヒドロフラン誘導化合物、β－ジヒドロフラン誘導化合物またはβ－テトラヒドロフラン誘導化合物の製造方法、β－グリコシド化合物、β－グリコシド化合物の製造方法、並びに、４'－エチニルｄ４Ｔ及びその類縁化合物の製造方法
US8975394B2 (en) 2010-02-15 2015-03-10 Nissan Chemical Industries, Ltd. Process for preparation of β-glycoside compounds
US9212174B2 (en) 2010-02-15 2015-12-15 Nissan Chemical Industries, Ltd. Certain β-dihydrofuran derivatives
JP5924479B2 (ja) * 2010-02-15 2016-05-25 日産化学工業株式会社 β−ジヒドロフラン誘導化合物、β−ジヒドロフラン誘導化合物またはβ−テトラヒドロフラン誘導化合物の製造方法、並びにβ−グリコシド化合物の製造方法

Also Published As

Publication number Publication date
NO20020129D0 (no) 2002-01-11
IL147449A0 (en) 2002-08-14
AP2002002395A0 (en) 2002-03-31
BR0012381A (pt) 2002-03-26
NO20020129L (no) 2002-03-11
PL352486A1 (en) 2003-08-25
FR2796384A1 (fr) 2001-01-19
CA2374411A1 (fr) 2001-01-18
WO2001004134A2 (fr) 2001-01-18
WO2001004134A3 (fr) 2001-09-27
AU6452300A (en) 2001-01-30

Similar Documents

Publication Publication Date Title
EP0717748B1 (fr) Composes 2' ou 3'-deoxy- et 2', 3'-dideoxy-beta-l-pentofuranonucleosides, procede de preparation et application therapeutique, notamment anti-virale
JPH06102655B2 (ja) ジフルオロ抗ウイルス剤の中間体
KR920004486B1 (ko) 시토신 누클레오시드의 제조방법
EP1373288B1 (en) Process for the preparation of 2'-halo-beta-l-arabinofuranosyl nucleosides
AU2002303187A1 (en) Process for the preparation of 2'-HALO-Beta-L-arabinofuranosyl nucleosides
EP0292101A2 (en) Process for the preparation of 3'-azido-3'-deoxythymidine and intermediates
KR20040021670A (ko) 리바비린의 제조방법
JP2003504377A (ja) ヌクレオシドから得られる新規ないエステルと、その製造方法と、それを含む医薬組成物
AU2006325622B2 (en) A manufacturing process of 2',2'-difluoronucleoside and intermediate
US7439351B2 (en) 2′ or 3′ -deoxy and 2′, 3′-dideoxy-β-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti-viral agents
CA2064916A1 (en) Substituted 2', 3'-dideoxy-5-trifluoromethyluridines, processes for their preparation and their use in medicaments
JP3046359B2 (ja) Ｄ−ペントフラノース誘導体及びその製造法
WO1990004603A1 (en) Nucleoside derivatives
WO1991006555A1 (en) Nucleoside derivative
JP3025559B2 (ja) アデノシン誘導体
JPS6152839B2 (no)
US7968521B2 (en) Stable cystal of protected pseudouridine
JPH0798833B2 (ja) ２′−ブロモ−２′，３′−ジデヒドロ−２′，３′−ジデオキシシチジン及びその製造法
JPH0692394B2 (ja) ２’，３’−ジデオキシシチジンの製造方法
JPH10330394A (ja) ヒドロキシアミノ置換ヌクレオシド誘導体
JP2001097993A (ja) ５−アルキル−２−チオシトシンヌクレオシドおよびその塩、ならびに該化合物を含有する抗ウイルス剤

Legal Events

Date Code Title Description
A300 Application deemed to be withdrawn because no request for examination was validly filed

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 20071002