JP2003504069A5 - - Google Patents
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- Publication number
- JP2003504069A5 JP2003504069A5 JP2001509533A JP2001509533A JP2003504069A5 JP 2003504069 A5 JP2003504069 A5 JP 2003504069A5 JP 2001509533 A JP2001509533 A JP 2001509533A JP 2001509533 A JP2001509533 A JP 2001509533A JP 2003504069 A5 JP2003504069 A5 JP 2003504069A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1999/27418 | 1999-07-08 | ||
| KR1019990027418A KR100356140B1 (ko) | 1999-07-08 | 1999-07-08 | 인간 과립구 콜로니 자극인자 변이체 및 이의 생산 방법 |
| PCT/KR2000/000733 WO2001004329A1 (en) | 1999-07-08 | 2000-07-07 | Modified human granulocyte-colony stimulating factor and process for producing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003504069A JP2003504069A (ja) | 2003-02-04 |
| JP2003504069A5 true JP2003504069A5 (https=) | 2005-12-22 |
Family
ID=36129291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001509533A Pending JP2003504069A (ja) | 1999-07-08 | 2000-07-07 | ヒト顆粒球コロニー刺激因子修飾体およびその生産方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20040224393A1 (https=) |
| EP (1) | EP1194575B2 (https=) |
| JP (1) | JP2003504069A (https=) |
| KR (1) | KR100356140B1 (https=) |
| CN (1) | CN1195859C (https=) |
| AT (1) | ATE299187T1 (https=) |
| AU (1) | AU757147C (https=) |
| BR (2) | BRPI0012265B8 (https=) |
| CA (1) | CA2378543C (https=) |
| DE (1) | DE60021188T3 (https=) |
| DK (1) | DK1194575T4 (https=) |
| ES (1) | ES2243275T5 (https=) |
| NZ (1) | NZ516476A (https=) |
| PT (1) | PT1194575E (https=) |
| RU (1) | RU2232772C2 (https=) |
| WO (1) | WO2001004329A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6831158B2 (en) | 2000-01-10 | 2004-12-14 | Maxygen Holdings Ltd. | G-CSF conjugates |
| EP1425304B9 (en) | 2001-07-11 | 2010-09-08 | Maxygen, Inc. | G-csf conjugates |
| DE60332358D1 (de) * | 2002-09-09 | 2010-06-10 | Hanall Pharmaceutical Co Ltd | Protease-resistente modifizierte interferon alpha polypeptide |
| US20090226397A1 (en) | 2003-10-24 | 2009-09-10 | Nora Therapeutics, Inc. | Compositions and methods for reducing the likelihood of implantation failure or miscarriage in recipients of artificial insemination |
| EP2196210A1 (en) | 2003-10-24 | 2010-06-16 | Nora, LLC | A method for reducing the likelihood of preeclampsia in a subject in need thereof |
| US8338373B2 (en) * | 2003-10-24 | 2012-12-25 | Nora Therapeutics, Inc. | Method for reducing the risk of spontaneous abortion in a human female subject |
| KR20080027291A (ko) | 2005-06-01 | 2008-03-26 | 맥시겐 홀딩스 엘티디 | 피이지화된 지-씨에스에프 폴리펩타이드 및 그 제조방법 |
| DE102005033250A1 (de) | 2005-07-15 | 2007-01-18 | Bioceuticals Arzneimittel Ag | Verfahren zur Reinigung von G-CSF |
| EP2274325A4 (en) * | 2008-05-13 | 2011-05-25 | Nora Therapeutics Inc | ANALOGUE OF HUMAN G-CSF AND METHOD OF MANUFACTURE AND APPLICATION THEREOF |
| PT2525787T (pt) | 2010-01-19 | 2017-12-18 | Hanmi Science Co Ltd | Formulações líquidas para conjugado de g-csf de longa ação |
| RU2612884C2 (ru) | 2010-04-02 | 2017-03-13 | Курна, Инк. | Лечение заболеваний, связанных с колониестимулирующим фактором 3 (csf3), путем ингибирования природного антисмыслового транскрипта k csf3 |
| KR101831300B1 (ko) * | 2010-10-29 | 2018-02-23 | 한미사이언스 주식회사 | 재조합 대장균으로부터 인간 과립구 콜로니 자극인자를 정제하는 방법 |
| RU2467764C2 (ru) * | 2011-01-12 | 2012-11-27 | Государственное бюджетное образовательное учреждение дополнительного профессионального образования "Пензенский институт усовершенствования врачей" Министерства здравоохранения и социального развития Российской Федерации | Способ лечения больных аутоиммунной хронической крапивницей с использованием внутривенного введения препарата "габриглобин" |
| WO2016013725A1 (ko) * | 2014-07-23 | 2016-01-28 | 주식회사 이큐스앤자루 | 과립구 콜로니 자극인자 변이 단백질 또는 이의 트랜스페린 융합 단백질을 유효성분으로 포함하는 약학적 조성물 |
| KR101623906B1 (ko) | 2014-07-23 | 2016-05-24 | 주식회사 이큐스앤자루 | 과립구 콜로니 자극인자 변이 단백질 또는 이의 트랜스페린 융합 단백질을 유효성분으로 포함하는 약학적 조성물 |
| CN110545849A (zh) | 2017-02-03 | 2019-12-06 | 韩美药品株式会社 | 具有增加的持续性的生理活性物质的缀合物及其应用 |
| US11267858B2 (en) | 2019-05-31 | 2022-03-08 | Spectrum Pharmaceuticals, Inc. | Methods of treatment using G-CSF protein complex |
| US11684655B2 (en) | 2019-05-31 | 2023-06-27 | Spectrum Pharmaceuticals, Inc. | Methods of treating neutorpenia using G-CSF protein complex |
| KR102375269B1 (ko) * | 2021-01-27 | 2022-03-17 | 한미약품 주식회사 | 단백질 액상 제제 및 이의 제조방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4810643A (en) * | 1985-08-23 | 1989-03-07 | Kirin- Amgen Inc. | Production of pluripotent granulocyte colony-stimulating factor |
| AU7675487A (en) * | 1986-08-11 | 1988-05-19 | Cetus Corporation | Expression of granulocyte colony-stimulating factor |
| US5362853A (en) * | 1986-12-23 | 1994-11-08 | Kyowa Hakko Kogyo Co., Ltd. | Polypeptide derivatives of human granulocyte colony stimulating factor |
| US5681720A (en) * | 1986-12-23 | 1997-10-28 | Kyowa Hakko Co., Ltd. | DNA encoding human granulocyte colony stimulating factor plasmids and host cells comprising same, and methods of expressing the encoded polypeptide |
| JPH02104598A (ja) | 1988-04-12 | 1990-04-17 | Kirin Amgen Inc | ヒト顆粒球コロニー刺激因子ポリペプチド誘導体 |
| NZ236819A (en) * | 1990-02-03 | 1993-07-27 | Max Planck Gesellschaft | Enzymatic cleavage of fusion proteins; fusion proteins; recombinant dna and pharmaceutical compositions |
| GB9107846D0 (en) * | 1990-04-30 | 1991-05-29 | Ici Plc | Polypeptides |
| EP0626448A3 (de) * | 1993-05-26 | 1998-01-14 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Herstellung und Reinigung von alpha-Interferon |
| US6476198B1 (en) * | 1993-07-13 | 2002-11-05 | The Scripps Research Institute | Multispecific and multivalent antigen-binding polypeptide molecules |
| US5451660A (en) * | 1993-12-13 | 1995-09-19 | Genentech, Inc. | Method for purifying polypeptides |
| JPH09511916A (ja) * | 1994-11-01 | 1997-12-02 | ベルス，ビンフリート | 核酸伝達系 |
| US6100070A (en) * | 1995-10-05 | 2000-08-08 | G. D. Searle & Co. | G-CSF receptor agonists |
| KR100316347B1 (ko) * | 1998-09-15 | 2002-08-27 | 한미약품(주) | 대장균엔테로톡신ⅱ신호펩티드의변형체와인체성장호르몬의융합단백질을발현하는재조합미생물및그를이용한인체성장호르몬의제조방법 |
| IL152804A0 (en) * | 2000-05-16 | 2003-06-24 | Bolder Biotechnology Inc | Methods for refolding proteins containing free cysteine residues |
-
1999
- 1999-07-08 KR KR1019990027418A patent/KR100356140B1/ko not_active Expired - Lifetime
-
2000
- 2000-07-07 RU RU2002103159/13A patent/RU2232772C2/ru active
- 2000-07-07 WO PCT/KR2000/000733 patent/WO2001004329A1/en not_active Ceased
- 2000-07-07 CA CA2378543A patent/CA2378543C/en not_active Expired - Lifetime
- 2000-07-07 NZ NZ516476A patent/NZ516476A/en not_active IP Right Cessation
- 2000-07-07 EP EP00942494A patent/EP1194575B2/en not_active Expired - Lifetime
- 2000-07-07 AU AU57106/00A patent/AU757147C/en not_active Expired
- 2000-07-07 PT PT00942494T patent/PT1194575E/pt unknown
- 2000-07-07 DK DK00942494T patent/DK1194575T4/da active
- 2000-07-07 DE DE60021188T patent/DE60021188T3/de not_active Expired - Lifetime
- 2000-07-07 CN CNB008100942A patent/CN1195859C/zh not_active Expired - Lifetime
- 2000-07-07 AT AT00942494T patent/ATE299187T1/de active
- 2000-07-07 BR BRPI0012265A patent/BRPI0012265B8/pt unknown
- 2000-07-07 ES ES00942494T patent/ES2243275T5/es not_active Expired - Lifetime
- 2000-07-07 JP JP2001509533A patent/JP2003504069A/ja active Pending
- 2000-07-07 BR BR0012265-3A patent/BR0012265A/pt not_active IP Right Cessation
-
2002
- 2002-01-09 US US10/031,123 patent/US20040224393A1/en not_active Abandoned
-
2007
- 2007-10-19 US US11/975,541 patent/US7704709B2/en not_active Expired - Fee Related