JP2003504052A5 - - Google Patents

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Publication number
JP2003504052A5
JP2003504052A5 JP2001509486A JP2001509486A JP2003504052A5 JP 2003504052 A5 JP2003504052 A5 JP 2003504052A5 JP 2001509486 A JP2001509486 A JP 2001509486A JP 2001509486 A JP2001509486 A JP 2001509486A JP 2003504052 A5 JP2003504052 A5 JP 2003504052A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001509486A
Other languages
Japanese (ja)
Other versions
JP2003504052A (ja
JP4361708B2 (ja
Filing date
Publication date
Priority claimed from US09/351,778 external-priority patent/US7589069B1/en
Application filed filed Critical
Publication of JP2003504052A publication Critical patent/JP2003504052A/ja
Publication of JP2003504052A5 publication Critical patent/JP2003504052A5/ja
Application granted granted Critical
Publication of JP4361708B2 publication Critical patent/JP4361708B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2001509486A 1999-07-12 2000-07-12 複製−コンピテント抗癌ベクター Expired - Fee Related JP4361708B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/351,778 US7589069B1 (en) 1999-07-12 1999-07-12 Replication-competent anti-cancer vectors
US09/351,778 1999-07-12
PCT/US2000/018971 WO2001004282A2 (en) 1999-07-12 2000-07-12 Replication-competent anti-cancer vectors

Publications (3)

Publication Number Publication Date
JP2003504052A JP2003504052A (ja) 2003-02-04
JP2003504052A5 true JP2003504052A5 (enExample) 2005-12-22
JP4361708B2 JP4361708B2 (ja) 2009-11-11

Family

ID=23382352

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001509486A Expired - Fee Related JP4361708B2 (ja) 1999-07-12 2000-07-12 複製−コンピテント抗癌ベクター

Country Status (9)

Country Link
US (3) US7589069B1 (enExample)
EP (1) EP1196616B1 (enExample)
JP (1) JP4361708B2 (enExample)
AT (1) ATE286139T1 (enExample)
AU (1) AU780613B2 (enExample)
CA (1) CA2378586C (enExample)
DE (1) DE60017141T2 (enExample)
ES (1) ES2231281T3 (enExample)
WO (1) WO2001004282A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7589069B1 (en) * 1999-07-12 2009-09-15 Saint Louis University Replication-competent anti-cancer vectors
CA2439185A1 (en) 2001-02-23 2002-09-06 Novartis Ag Vector constructs
US8163892B2 (en) * 2002-07-08 2012-04-24 Oncolys Biopharma, Inc. Oncolytic virus replicating selectively in tumor cells
US20040213764A1 (en) * 2003-03-28 2004-10-28 William Wold Adenovirus replication-competent vectors expressing trail
CN1871034B (zh) * 2003-07-09 2011-07-06 亨利福特保健系统公司 用新型腺病毒治疗癌症的方法和组合物
US7815902B2 (en) 2003-07-09 2010-10-19 Henry Ford Health System Methods and compositions for cancer therapy using a novel adenovirus
WO2005049094A1 (en) * 2003-11-13 2005-06-02 Advantagene, Inc. A mixed complementary viral vector for gene therapy
WO2008136213A1 (ja) * 2007-04-27 2008-11-13 Oncolys Biopharma Inc. 放射線増感増強剤
US8696544B2 (en) 2009-02-05 2014-04-15 Coloplast A/S Minimally invasive adjustable support
WO2011146885A2 (en) * 2010-05-21 2011-11-24 Virxsys Corporation Compositions and methods for lentiviral expression of apoa-1 or variants thereof using spliceosome mediated rna trans-splicing
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (en) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
WO2018111902A1 (en) 2016-12-12 2018-06-21 Multivir Inc. Methods and compositions comprising viral gene therapy and an immune checkpoint inhibitor for treatment and prevention of cancer and infectious diseases
CA3094329A1 (en) 2018-03-19 2020-02-20 Multivir Inc. Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer
BR112020019942A2 (pt) * 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
WO2021113644A1 (en) 2019-12-05 2021-06-10 Multivir Inc. Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846945A (en) 1993-02-16 1998-12-08 Onyx Pharmaceuticals, Inc. Cytopathic viruses for therapy and prophylaxis of neoplasia
US5631236A (en) * 1993-08-26 1997-05-20 Baylor College Of Medicine Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
US6254862B1 (en) 1997-03-03 2001-07-03 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US6197293B1 (en) * 1997-03-03 2001-03-06 Calydon, Inc. Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof
US6627190B2 (en) * 1999-07-12 2003-09-30 Saint Louis University Recombinant adenovirus vectors that are replication-competent in tert-expressing cells
US7589069B1 (en) * 1999-07-12 2009-09-15 Saint Louis University Replication-competent anti-cancer vectors

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