JP2003503370A5 - - Google Patents

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Publication number
JP2003503370A5
JP2003503370A5 JP2001506715A JP2001506715A JP2003503370A5 JP 2003503370 A5 JP2003503370 A5 JP 2003503370A5 JP 2001506715 A JP2001506715 A JP 2001506715A JP 2001506715 A JP2001506715 A JP 2001506715A JP 2003503370 A5 JP2003503370 A5 JP 2003503370A5
Authority
JP
Japan
Prior art keywords
combination according
combination
copolymer
carrier
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001506715A
Other languages
English (en)
Japanese (ja)
Other versions
JP5025059B2 (ja
JP2003503370A (ja
Filing date
Publication date
Priority claimed from EP99112260A external-priority patent/EP1063254A1/de
Priority claimed from DE1999156502 external-priority patent/DE19956502A1/de
Application filed filed Critical
Priority claimed from PCT/EP2000/005778 external-priority patent/WO2001000708A1/de
Publication of JP2003503370A publication Critical patent/JP2003503370A/ja
Publication of JP2003503370A5 publication Critical patent/JP2003503370A5/ja
Application granted granted Critical
Publication of JP5025059B2 publication Critical patent/JP5025059B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2001506715A 1999-06-25 2000-06-21 核酸を細胞に導入するための配合剤 Expired - Fee Related JP5025059B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP99112260.7 1999-06-25
EP99112260A EP1063254A1 (de) 1999-06-25 1999-06-25 Copolymere für den Transport von Nukleinsäuren in die Zelle
DE19956502.3 1999-11-24
DE1999156502 DE19956502A1 (de) 1999-11-24 1999-11-24 Kombinationen zur Einführung von Nucleinsäuren in Zellen
PCT/EP2000/005778 WO2001000708A1 (de) 1999-06-25 2000-06-21 Kombinationen zur einführung von nucleinsäuren in zellen

Publications (3)

Publication Number Publication Date
JP2003503370A JP2003503370A (ja) 2003-01-28
JP2003503370A5 true JP2003503370A5 (https=) 2007-08-16
JP5025059B2 JP5025059B2 (ja) 2012-09-12

Family

ID=26055629

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001506715A Expired - Fee Related JP5025059B2 (ja) 1999-06-25 2000-06-21 核酸を細胞に導入するための配合剤

Country Status (9)

Country Link
US (2) US20030026840A1 (https=)
EP (1) EP1198489B1 (https=)
JP (1) JP5025059B2 (https=)
AT (1) ATE265488T1 (https=)
AU (1) AU776715B2 (https=)
CA (1) CA2377207C (https=)
DE (1) DE50006269D1 (https=)
ES (1) ES2219346T3 (https=)
WO (1) WO2001000708A1 (https=)

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JP5170934B2 (ja) * 2001-08-16 2013-03-27 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 改良ｄｎａリポフェクションならびに／または徐放性プロドラッグおよび薬物療法のための試薬の合成と使用
US8740973B2 (en) * 2001-10-26 2014-06-03 Icon Medical Corp. Polymer biodegradable medical device
WO2003059382A2 (en) * 2001-12-28 2003-07-24 Supratek Pharma Inc. Pharmaceutical compositions comprising polyanionic polymers and amphiphilic block copolymers and methods of use thereof to improve gene expression
US8016881B2 (en) * 2002-07-31 2011-09-13 Icon Interventional Systems, Inc. Sutures and surgical staples for anastamoses, wound closures, and surgical closures
JP5153072B2 (ja) 2003-04-18 2013-02-27 独立行政法人国立循環器病研究センター ベクター
US7883720B2 (en) 2003-07-09 2011-02-08 Wisconsin Alumni Research Foundation Charge-dynamic polymers and delivery of anionic compounds
US7211108B2 (en) * 2004-01-23 2007-05-01 Icon Medical Corp. Vascular grafts with amphiphilic block copolymer coatings
WO2006110197A2 (en) 2005-03-03 2006-10-19 Icon Medical Corp. Polymer biodegradable medical device
US20060201601A1 (en) * 2005-03-03 2006-09-14 Icon Interventional Systems, Inc. Flexible markers
US7540995B2 (en) * 2005-03-03 2009-06-02 Icon Medical Corp. Process for forming an improved metal alloy stent
US8323333B2 (en) * 2005-03-03 2012-12-04 Icon Medical Corp. Fragile structure protective coating
US9107899B2 (en) 2005-03-03 2015-08-18 Icon Medical Corporation Metal alloys for medical devices
US20060264914A1 (en) * 2005-03-03 2006-11-23 Icon Medical Corp. Metal alloys for medical devices
AU2006221046B2 (en) * 2005-03-03 2012-02-02 Icon Medical Corp. Improved metal alloys for medical device
US8734851B2 (en) * 2005-04-29 2014-05-27 Wisconsin Alumni Research Foundation Localized delivery of nucleic acid by polyelectrolyte assemblies
JP4870941B2 (ja) * 2005-05-09 2012-02-08 公立大学法人大阪府立大学 高分子化合物
US20060263328A1 (en) * 2005-05-19 2006-11-23 Sang Van Hydrophilic polymers with pendant functional groups and method thereof
KR100777249B1 (ko) * 2006-02-14 2007-11-28 (주)바이오니아 건조 올리고뉴클레오티드 조성물 및 이의 제조 방법
WO2008008291A2 (en) * 2006-07-13 2008-01-17 Icon Medical Corp. Stent
US8834918B2 (en) * 2007-01-22 2014-09-16 Wisconsin Alumni Research Foundation Modified multilayered film
WO2009049100A2 (en) 2007-10-09 2009-04-16 Wisconsin Alumni Research Foundation Ultrathin multilayered films for controlled release of anionic reagents
JP5392674B2 (ja) * 2008-04-03 2014-01-22 公立大学法人大阪府立大学 コラーゲン医薬組成物及びその製造方法
US8324333B2 (en) 2008-06-05 2012-12-04 Wisconsin Alumni Research Foundation Anionic charge-dynamic polymers for release of cationic agents
EP2306929A1 (en) * 2008-07-14 2011-04-13 SurModics, Inc. Medical devices and methods for delivery of nucleic acids
CA2769670C (en) 2009-07-31 2018-10-02 Ethris Gmbh Rna with a combination of unmodified and modified nucleotides for protein expression
JPWO2011096408A1 (ja) * 2010-02-02 2013-06-10 国立大学法人 東京大学 複合体微粒子およびその製造方法、ならびに該複合体微粒子を用いた薬学組成物
US8398916B2 (en) 2010-03-04 2013-03-19 Icon Medical Corp. Method for forming a tubular medical device
US9057067B2 (en) 2010-07-10 2015-06-16 Kinki University Method for transfecting nucleic acid to cell and nucleic acid complex
WO2012175617A1 (en) * 2011-06-24 2012-12-27 Stichting Dutch Polymer Institute Diblock copolymer
US12064484B2 (en) 2013-06-28 2024-08-20 Ethris Gmbh Compositions for introducing RNA into cells
JP2017507946A (ja) 2014-02-26 2017-03-23 エスリス ゲーエムベーハーｅｔｈｒｉｓ ＧｍｂＨ Ｒｎａを胃腸内投与するための組成物
BR112016030273A2 (pt) 2014-06-24 2017-08-22 Icon Medical Corp Dispositivo médico e método para formar o referido dispositivo
WO2016075154A1 (en) 2014-11-10 2016-05-19 Ethris Gmbh Induction of osteogenesis by delivering bmp encoding rna
EP3034539A1 (en) 2014-12-19 2016-06-22 Ethris GmbH Compositions for introducing nucleic acid into cells
EP3115039B1 (de) * 2015-07-09 2021-12-15 beniag GmbH Verfahren zum herstellen einer fusionsmischung zur übertragung eines geladenen moleküls in und/oder durch eine lipidmembran
WO2017151548A1 (en) 2016-03-04 2017-09-08 Mirus Llc Stent device for spinal fusion
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
WO2018127382A1 (en) 2017-01-03 2018-07-12 Ethris Gmbh Ornithine transcarbamylase coding polyribonucleotides and formulations thereof
HUE065017T2 (hu) 2019-02-14 2024-04-28 Ethris Gmbh Poliribonukleotid ciliogenezisre gyakorolt hatásának elemzése
WO2024121160A1 (en) 2022-12-05 2024-06-13 Ethris Gmbh Regulator(s) of energy homeostasis-encoding rna molecule(s) with increased translation efficiency
CN121335708A (zh) 2023-05-01 2026-01-13 耶鲁大学 用于疫苗接种的抗原特异性生理性树突状细胞
WO2024227806A1 (en) 2023-05-01 2024-11-07 Yale University Antigen-specific physiologic dendritic cells for therapy
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US5763416A (en) * 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
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US5863984A (en) * 1995-12-01 1999-01-26 Universite Laval, Cite Universitaire Biostable porous material comprising composite biopolymers
GB9600272D0 (en) * 1996-01-06 1996-03-06 Univ Nottingham Polymers
JP3808938B2 (ja) * 1996-07-16 2006-08-16 久光製薬株式会社 核酸運搬体
GB9623051D0 (en) * 1996-11-06 1997-01-08 Schacht Etienne H Delivery of DNA to target cells in biological systems

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