JP2002542204A5 - - Google Patents
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- Publication number
- JP2002542204A5 JP2002542204A5 JP2000611937A JP2000611937A JP2002542204A5 JP 2002542204 A5 JP2002542204 A5 JP 2002542204A5 JP 2000611937 A JP2000611937 A JP 2000611937A JP 2000611937 A JP2000611937 A JP 2000611937A JP 2002542204 A5 JP2002542204 A5 JP 2002542204A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine composition
- rsv
- composition according
- streptococcus pneumoniae
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005486 vaccine Drugs 0.000 description 16
- 239000000203 mixture Substances 0.000 description 14
- 241000725643 Respiratory syncytial virus Species 0.000 description 10
- 241000193998 Streptococcus pneumoniae Species 0.000 description 8
- 239000000427 antigen Substances 0.000 description 8
- 102000036639 antigens Human genes 0.000 description 8
- 108091007433 antigens Proteins 0.000 description 8
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 8
- 150000004676 glycans Chemical class 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- 239000002671 adjuvant Substances 0.000 description 4
- 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 description 3
- 101710188053 Protein D Proteins 0.000 description 3
- 101710132893 Resolvase Proteins 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 108020001507 fusion proteins Proteins 0.000 description 2
- 102000037865 fusion proteins Human genes 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 229940031831 23-valent pneumococcal polysaccharide vaccine Drugs 0.000 description 1
- 102000016607 Diphtheria Toxin Human genes 0.000 description 1
- 108010053187 Diphtheria Toxin Proteins 0.000 description 1
- 101710121417 Envelope glycoprotein Proteins 0.000 description 1
- 241000606768 Haemophilus influenzae Species 0.000 description 1
- 241000711920 Human orthopneumovirus Species 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 102100021696 Syncytin-1 Human genes 0.000 description 1
- 108010055044 Tetanus Toxin Proteins 0.000 description 1
- 108010046722 Thrombospondin 1 Proteins 0.000 description 1
- 102100036034 Thrombospondin-1 Human genes 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 229940047650 haemophilus influenzae Drugs 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229940031960 pneumococcal polysaccharide vaccine Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 229940118376 tetanus toxin Drugs 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9909077.1A GB9909077D0 (en) | 1999-04-20 | 1999-04-20 | Novel compositions |
| GB9909077.1 | 1999-04-20 | ||
| PCT/EP2000/003514 WO2000062801A2 (en) | 1999-04-20 | 2000-04-17 | Combination vaccine against streptococcus pneumoniae and respiratory syncytial virus (rsv) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002542204A JP2002542204A (ja) | 2002-12-10 |
| JP2002542204A5 true JP2002542204A5 (https=) | 2007-06-14 |
Family
ID=10851924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000611937A Pending JP2002542204A (ja) | 1999-04-20 | 2000-04-17 | ストレプトコッカス・ニューモニエ及び呼吸性シンシチウムウィルス（ｒｓｖ）に対する複合ワクチン |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20040228879A1 (https=) |
| EP (2) | EP1171159B1 (https=) |
| JP (1) | JP2002542204A (https=) |
| KR (1) | KR100632835B1 (https=) |
| CN (1) | CN1192797C (https=) |
| AR (1) | AR023535A1 (https=) |
| AT (1) | ATE395079T1 (https=) |
| AU (1) | AU754101B2 (https=) |
| BR (1) | BR0010682A (https=) |
| CA (1) | CA2365579A1 (https=) |
| CO (1) | CO5300414A1 (https=) |
| CZ (1) | CZ20013773A3 (https=) |
| DE (1) | DE60038877D1 (https=) |
| ES (1) | ES2304960T3 (https=) |
| GB (1) | GB9909077D0 (https=) |
| HK (1) | HK1045100A1 (https=) |
| HU (1) | HUP0201905A3 (https=) |
| IL (1) | IL145981A0 (https=) |
| MY (1) | MY125000A (https=) |
| NO (1) | NO20015074L (https=) |
| NZ (1) | NZ514961A (https=) |
| PL (1) | PL351894A1 (https=) |
| TR (1) | TR200103012T2 (https=) |
| TW (1) | TWI234463B (https=) |
| WO (1) | WO2000062801A2 (https=) |
| ZA (1) | ZA200108620B (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| ES2275499T3 (es) | 1999-03-19 | 2007-06-16 | Glaxosmithkline Biologicals S.A. | Vacuna contra streptococcus pneumoniae. |
| GB0000891D0 (en) * | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| AUPQ761200A0 (en) | 2000-05-19 | 2000-06-15 | Hunter Immunology Limited | Compositions and methods for treatment of mucosal infections |
| FR2828406B1 (fr) * | 2001-08-08 | 2005-06-24 | Aventis Pasteur | Composition vaccinale bivalente havi |
| RU2252784C1 (ru) * | 2003-12-29 | 2005-05-27 | НИИ вакцин и сывороток им. И.И. Мечникова РАМН | Способ профилактики обострений хронических воспалительных заболеваний легких у детей |
| CA2604363C (en) | 2005-04-08 | 2015-06-16 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US9839685B2 (en) | 2006-04-13 | 2017-12-12 | The Regents Of The University Of Michigan | Methods of inducing human immunodeficiency virus-specific immune responses in a host comprising nasally administering compositions comprising a naonemulsion and recombinant GP120 immunogen |
| TW200806315A (en) | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
| US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
| SI2271360T1 (sl) * | 2008-04-16 | 2015-12-31 | Glaxosmithkline Biologicals S.A. | Cepivo |
| BRPI1014031A2 (pt) * | 2009-06-16 | 2018-02-20 | Univ Michigan Regents | vacinas de nanoemulsão |
| CN102695523A (zh) | 2009-09-10 | 2012-09-26 | 诺华有限公司 | 针对呼吸道疾病的组合疫苗 |
| CN101703769B (zh) * | 2009-11-13 | 2013-05-08 | 广东永顺生物制药股份有限公司 | 一种新型猪链球菌病四价灭活疫苗 |
| PT2575870T (pt) * | 2010-06-04 | 2017-02-10 | Wyeth Llc | Formulações de vacinas |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| RU2017120039A (ru) | 2014-12-10 | 2019-01-10 | Дженентек, Инк. | Антитела к рецепторам гематоэнцефалического барьера и способы их применения |
| PH12018500305B1 (en) * | 2015-09-10 | 2023-03-15 | Inventprise Llc | Multivalent vlp conjugates |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| US11389519B2 (en) | 2018-06-11 | 2022-07-19 | Inventprise, Llc | Virus-like particle conjugates |
| PH12022552827A1 (en) * | 2020-05-01 | 2024-02-12 | Sinocelltech Ltd | Method for improving immunogenicity of protein/peptide antigen |
| CN119317445A (zh) | 2022-05-11 | 2025-01-14 | 辉瑞公司 | 用于生产含有防腐剂的疫苗制剂的方法 |
| WO2024241172A2 (en) * | 2023-05-19 | 2024-11-28 | Glaxosmithkline Biologicals Sa | Methods for eliciting an immune response to respiratory syncycial virus and streptococcus pneumoniae infection |
| CN117717608B (zh) * | 2023-12-15 | 2025-05-16 | 北京吉诺卫生物科技有限公司 | 一种包含肺炎球菌与流感病毒的联合疫苗、制备方法及其应用 |
| WO2026038177A1 (en) * | 2024-08-16 | 2026-02-19 | Pfizer Inc. | Immunogenic compositions and uses thereof |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| US4372945A (en) | 1979-11-13 | 1983-02-08 | Likhite Vilas V | Antigen compounds |
| IL61904A (en) | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
| BE889979A (fr) | 1981-08-14 | 1982-02-15 | Smith Kline Rit | Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation |
| US5149650A (en) | 1986-01-14 | 1992-09-22 | University Of North Carolina At Chapel Hill | Vaccines for human respiratory virus |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| KR0137963B1 (ko) | 1987-12-23 | 1998-04-30 | 로버트 에이. 아미테이지 | 인간의 호흡기 합포체성 바이러스에 대한 당단백질 면역 단편을 함유하는 키메라(chimeric) 당단백질 |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| DK0671948T3 (da) | 1992-06-25 | 1997-09-01 | Smithkline Beecham Biolog | Vaccinepræparat indeholdende adjuvanser |
| ATE157882T1 (de) | 1993-03-23 | 1997-09-15 | Smithkline Beecham Biolog | 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen |
| EP0705109B2 (en) * | 1993-05-25 | 2004-01-02 | American Cyanamid Company | Adjuvants for vaccines against respiratory syncytial virus |
| NZ274376A (en) | 1993-09-22 | 1997-11-24 | Jackson H M Found Military Med | Activating soluble carbohydrate using cyanylating reagents for the production of immunogenic constructs |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US6764682B1 (en) * | 1994-06-16 | 2004-07-20 | Aventis Pasteur Limited | Adjuvant compositions containing more than one adjuvant |
| ATE509102T1 (de) | 1994-07-15 | 2011-05-15 | Univ Iowa Res Found | Immunomodulatorische oligonukleotide |
| WO1996032963A1 (en) * | 1995-04-17 | 1996-10-24 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Induction and enhancement of the immune response to polysaccharides with bacterial lipoproteins |
| UA56132C2 (uk) * | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| GB9620795D0 (en) * | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
| AU1146597A (en) * | 1995-12-06 | 1997-06-27 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Compositions and method for stimulating antibody release by b lymphocytes |
| SE9601158D0 (sv) * | 1996-03-26 | 1996-03-26 | Stefan Svenson | Method of producing immunogenic products and vaccines |
| US6020182A (en) * | 1996-07-12 | 2000-02-01 | Connaught Laboratories Limited | Subunit respiratory syncytial virus vaccine preparation |
| WO1998018819A1 (en) * | 1996-10-29 | 1998-05-07 | Smithkline Beecham Biologicals S.A. | Purification of respiratory syncytial virus antigens |
| US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| FR2763244B1 (fr) * | 1997-05-14 | 2003-08-01 | Pasteur Merieux Serums Vacc | Composition vaccinale multivalente a porteur mixte |
| GB9712347D0 (en) * | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
-
1999
- 1999-04-20 GB GBGB9909077.1A patent/GB9909077D0/en not_active Ceased
-
2000
- 2000-04-17 AT AT00940231T patent/ATE395079T1/de not_active IP Right Cessation
- 2000-04-17 ES ES00940231T patent/ES2304960T3/es not_active Expired - Lifetime
- 2000-04-17 HK HK02104796.6A patent/HK1045100A1/zh unknown
- 2000-04-17 TR TR2001/03012T patent/TR200103012T2/xx unknown
- 2000-04-17 AU AU55233/00A patent/AU754101B2/en not_active Ceased
- 2000-04-17 CZ CZ20013773A patent/CZ20013773A3/cs unknown
- 2000-04-17 CN CNB00809053XA patent/CN1192797C/zh not_active Expired - Fee Related
- 2000-04-17 PL PL00351894A patent/PL351894A1/xx not_active Application Discontinuation
- 2000-04-17 BR BR0010682-8A patent/BR0010682A/pt not_active IP Right Cessation
- 2000-04-17 HU HU0201905A patent/HUP0201905A3/hu not_active Application Discontinuation
- 2000-04-17 DE DE60038877T patent/DE60038877D1/de not_active Expired - Lifetime
- 2000-04-17 NZ NZ514961A patent/NZ514961A/en unknown
- 2000-04-17 EP EP00940231A patent/EP1171159B1/en not_active Expired - Lifetime
- 2000-04-17 WO PCT/EP2000/003514 patent/WO2000062801A2/en not_active Ceased
- 2000-04-17 JP JP2000611937A patent/JP2002542204A/ja active Pending
- 2000-04-17 EP EP08151478A patent/EP1927366A1/en not_active Withdrawn
- 2000-04-17 KR KR1020017013365A patent/KR100632835B1/ko not_active Expired - Fee Related
- 2000-04-17 CA CA002365579A patent/CA2365579A1/en not_active Abandoned
- 2000-04-17 IL IL14598100A patent/IL145981A0/xx unknown
- 2000-04-18 AR ARP000101808A patent/AR023535A1/es not_active Application Discontinuation
- 2000-04-18 MY MYPI20001649A patent/MY125000A/en unknown
- 2000-04-19 CO CO00028930A patent/CO5300414A1/es not_active Application Discontinuation
- 2000-04-20 TW TW089107452A patent/TWI234463B/zh not_active IP Right Cessation
-
2001
- 2001-10-18 NO NO20015074A patent/NO20015074L/no not_active Application Discontinuation
- 2001-10-19 ZA ZA200108620A patent/ZA200108620B/en unknown
-
2004
- 2004-06-15 US US10/867,880 patent/US20040228879A1/en not_active Abandoned
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