JP2002538207A5 - - Google Patents
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- Publication number
- JP2002538207A5 JP2002538207A5 JP2000603671A JP2000603671A JP2002538207A5 JP 2002538207 A5 JP2002538207 A5 JP 2002538207A5 JP 2000603671 A JP2000603671 A JP 2000603671A JP 2000603671 A JP2000603671 A JP 2000603671A JP 2002538207 A5 JP2002538207 A5 JP 2002538207A5
- Authority
- JP
- Japan
- Prior art keywords
- multiple sclerosis
- cyclopropylmethoxy
- difluoromethoxy
- benzamide
- dichloropyrid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 201000006417 multiple sclerosis Diseases 0.000 description 12
- 239000003814 drug Substances 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 239000002775 capsule Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 150000001204 N-oxides Chemical class 0.000 description 1
- 206010053395 Progressive multiple sclerosis Diseases 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000009517 secondary packaging Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99104793 | 1999-03-10 | ||
| EP99104793.7 | 1999-03-10 | ||
| PCT/EP2000/001703 WO2000053182A2 (en) | 1999-03-10 | 2000-03-01 | 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002538207A JP2002538207A (ja) | 2002-11-12 |
| JP2002538207A5 true JP2002538207A5 (enExample) | 2007-05-10 |
Family
ID=8237737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000603671A Pending JP2002538207A (ja) | 1999-03-10 | 2000-03-01 | 多発性硬化症治療のための３−シクロプロピルメトキシ−４−ジフルオロメトキシ−ｎ−（３，５−ジクロロピリド−４−イル）ベンズアミド |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6531493B1 (enExample) |
| EP (1) | EP1161239B1 (enExample) |
| JP (1) | JP2002538207A (enExample) |
| AT (1) | ATE279924T1 (enExample) |
| AU (1) | AU3284000A (enExample) |
| CA (1) | CA2364258C (enExample) |
| DE (1) | DE60015098T2 (enExample) |
| DK (1) | DK1161239T3 (enExample) |
| ES (1) | ES2231162T3 (enExample) |
| PT (1) | PT1161239E (enExample) |
| SI (1) | SI1161239T1 (enExample) |
| WO (1) | WO2000053182A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1199074A1 (en) * | 2000-09-15 | 2002-04-24 | Warner-Lambert Company | Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production |
| EP1188438A1 (en) * | 2000-09-15 | 2002-03-20 | Warner-Lambert Company | Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production |
| WO2002088079A2 (en) * | 2001-05-01 | 2002-11-07 | Bristol-Myers Squibb Company | Dual inhibitors of pde 7 and pde 4 |
| US20030092706A1 (en) * | 2001-11-09 | 2003-05-15 | Johannes Barsig | Combination |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| HUE039709T2 (hu) | 2002-05-28 | 2019-01-28 | Astrazeneca Ab | Helyileg alkalmazandó gyógyászati készítmény |
| US6822114B1 (en) | 2002-10-08 | 2004-11-23 | Albemarle Corporation | Process for production of fluoroalkoxy-substituted benzamides and their intermediates |
| ES2335498T3 (es) | 2003-03-10 | 2010-03-29 | Nycomed Gmbh | Nuevo proceso para la preparacion de reflumilast. |
| DE102004046235A1 (de) | 2004-09-22 | 2006-03-30 | Altana Pharma Ag | Arzneimittelzubereitung |
| EP2258350B1 (en) * | 2005-03-16 | 2014-12-24 | Takeda GmbH | Taste masked dosage form containing roflumilast |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9304571A (es) * | 1992-07-28 | 1994-05-31 | Rhone Poulenc Rorer Ltd | Compuestos fanilicos ligados a un arilo o heteroarilo mediante un radical alifatico o un atomo heterogeneo que contiene un grupo eslabonador. |
| KR100331255B1 (ko) | 1993-07-02 | 2002-10-25 | 빅굴덴 롬베르그 케미쉐 화부리크 게엠베하 | 플루오로알콕시-치환된벤즈아미드및시클릭뉴클레오티드포스포디에스테라아제억제제로서의그의용도 |
| EP0758233B1 (en) | 1994-04-21 | 2003-12-03 | Schering Aktiengesellschaft | Pde iv inhibitors for treating multiple sclerosis |
-
2000
- 2000-03-01 PT PT00910736T patent/PT1161239E/pt unknown
- 2000-03-01 JP JP2000603671A patent/JP2002538207A/ja active Pending
- 2000-03-01 SI SI200030586T patent/SI1161239T1/xx unknown
- 2000-03-01 US US09/914,763 patent/US6531493B1/en not_active Expired - Lifetime
- 2000-03-01 CA CA002364258A patent/CA2364258C/en not_active Expired - Fee Related
- 2000-03-01 WO PCT/EP2000/001703 patent/WO2000053182A2/en not_active Ceased
- 2000-03-01 EP EP00910736A patent/EP1161239B1/en not_active Expired - Lifetime
- 2000-03-01 DE DE60015098T patent/DE60015098T2/de not_active Expired - Lifetime
- 2000-03-01 ES ES00910736T patent/ES2231162T3/es not_active Expired - Lifetime
- 2000-03-01 AT AT00910736T patent/ATE279924T1/de active
- 2000-03-01 AU AU32840/00A patent/AU3284000A/en not_active Abandoned
- 2000-03-01 DK DK00910736T patent/DK1161239T3/da active
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