PT1161239E - 3-ciclopropilmetoxi-4-difluorometoxi-n-(3,5-dicloropirid-4-il)-benzamida para o tratamento da esclerose multipla - Google Patents

3-ciclopropilmetoxi-4-difluorometoxi-n-(3,5-dicloropirid-4-il)-benzamida para o tratamento da esclerose multipla

Info

Publication number
PT1161239E
PT1161239E PT00910736T PT00910736T PT1161239E PT 1161239 E PT1161239 E PT 1161239E PT 00910736 T PT00910736 T PT 00910736T PT 00910736 T PT00910736 T PT 00910736T PT 1161239 E PT1161239 E PT 1161239E
Authority
PT
Portugal
Prior art keywords
dichloropyrid
cyclopropylmethoxy
difluoromethoxy
benzamide
treatment
Prior art date
Application number
PT00910736T
Other languages
English (en)
Portuguese (pt)
Inventor
Christian Schudt
Armin Hatzelmann
Hermann Amschler
Karl Sanders
Kley Hans-Peter
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PT1161239E publication Critical patent/PT1161239E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PT00910736T 1999-03-10 2000-03-01 3-ciclopropilmetoxi-4-difluorometoxi-n-(3,5-dicloropirid-4-il)-benzamida para o tratamento da esclerose multipla PT1161239E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99104793 1999-03-10
PCT/EP2000/001703 WO2000053182A2 (en) 1999-03-10 2000-03-01 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
PT1161239E true PT1161239E (pt) 2005-02-28

Family

ID=8237737

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00910736T PT1161239E (pt) 1999-03-10 2000-03-01 3-ciclopropilmetoxi-4-difluorometoxi-n-(3,5-dicloropirid-4-il)-benzamida para o tratamento da esclerose multipla

Country Status (12)

Country Link
US (1) US6531493B1 (enExample)
EP (1) EP1161239B1 (enExample)
JP (1) JP2002538207A (enExample)
AT (1) ATE279924T1 (enExample)
AU (1) AU3284000A (enExample)
CA (1) CA2364258C (enExample)
DE (1) DE60015098T2 (enExample)
DK (1) DK1161239T3 (enExample)
ES (1) ES2231162T3 (enExample)
PT (1) PT1161239E (enExample)
SI (1) SI1161239T1 (enExample)
WO (1) WO2000053182A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1199074A1 (en) * 2000-09-15 2002-04-24 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production
EP1188438A1 (en) * 2000-09-15 2002-03-20 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production
WO2002088079A2 (en) * 2001-05-01 2002-11-07 Bristol-Myers Squibb Company Dual inhibitors of pde 7 and pde 4
US20030092706A1 (en) * 2001-11-09 2003-05-15 Johannes Barsig Combination
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
NZ537308A (en) 2002-05-28 2009-09-25 Nycomed Gmbh Ophthalmological use of roflumilast for the treatment of diseases of the eye
US6822114B1 (en) 2002-10-08 2004-11-23 Albemarle Corporation Process for production of fluoroalkoxy-substituted benzamides and their intermediates
KR101179012B1 (ko) 2003-03-10 2012-09-03 니코메드 게엠베하 로플루미라스트 신규한 제조 방법
DE102004046235A1 (de) 2004-09-22 2006-03-30 Altana Pharma Ag Arzneimittelzubereitung
EP1861074B1 (en) * 2005-03-16 2013-04-24 Takeda GmbH Taste masked dosage form containing roflumilast

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL106517A0 (en) * 1992-07-28 1994-08-26 Rhone Poulenc Rorer Ltd Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic or heteroatom containing linking group
US5712298A (en) * 1993-07-02 1998-01-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Fluoroalkoxy-substituted benzamides and their use as cyclic nucleotide phosphodiesterase inhibitors
ATE255413T1 (de) * 1994-04-21 2003-12-15 Schering Ag Pde iv-inhibitoren zur behandlung der multiplen sklerose

Also Published As

Publication number Publication date
DK1161239T3 (da) 2005-02-14
JP2002538207A (ja) 2002-11-12
DE60015098D1 (de) 2004-11-25
ES2231162T3 (es) 2005-05-16
US6531493B1 (en) 2003-03-11
EP1161239A2 (en) 2001-12-12
WO2000053182A3 (en) 2001-04-12
CA2364258A1 (en) 2000-09-14
WO2000053182A2 (en) 2000-09-14
SI1161239T1 (en) 2005-06-30
ATE279924T1 (de) 2004-11-15
DE60015098T2 (de) 2006-02-02
CA2364258C (en) 2008-12-30
AU3284000A (en) 2000-09-28
EP1161239B1 (en) 2004-10-20

Similar Documents

Publication Publication Date Title
BR0209580A (pt) Derivados de ciclohexan-1, 4 diamina substituìdos
DK1525177T3 (da) Substituerede 1,3-diphenylprop-2-en-1-on-derivater, fremstilling og anvendelse deraf
NO20033566L (no) Acylerte 6,7,8,9-tetrehydro-5H-benzocykloheptenyl-aminer og deres anvendelse som farmasöytiske midler
DK1178958T3 (da) N-cyanomethylamider som proteaseinhibitorer
TR200101859T2 (tr) Kemokin alıcı aktivitesinin modülatörleri olarak N-üreidoalkil-piperidinler
BR0214263B1 (pt) processos para a preparaÇço de uma composiÇço para o tratamento dos cabelos.
DE60133389D1 (de) Gabapentinanaloga für schlafstörungen
DK1280799T3 (da) Orthosubstituerede anthranilsyreamider og anvendelse heraf som lægemidler
BR0009480A (pt) Soluções de poliuretano com unidades de estrutura de alcoxissilano
SE0101932D0 (sv) Pharmaceutical combinations
BR0114903A (pt) 7-azaindóis, sua aplicação como inibidores da fosfodiesterase 4 e processos para a sua preparação
ATE303384T1 (de) 1-biaryl-1,8-naphthyridin-4-one als phosphodieseterase-inhibitoren
PT1161239E (pt) 3-ciclopropilmetoxi-4-difluorometoxi-n-(3,5-dicloropirid-4-il)-benzamida para o tratamento da esclerose multipla
IS2212B (is) 2-(3,5-Bis-trifluoromethyl-phenyl)-N-methyl-N-(6-morpholin-4-yl-4-o-tolyl-pyridin-3-yl)-isobutyrarramide
DK1404304T3 (da) Tablet omfattende cetirizin og pseudoephedrin
IL126110A0 (en) Use of aryl n-substituted carboxamides to kill tumors and novel compounds for such use
DK1379508T3 (da) N-(aryl)-2arylethensulfonamider og terapeutiske anvendelser deraf
DK1463735T3 (da) Imidazo-2,1-B -1,3,4-thiadiazol-sulfonamider
HRP20031057B1 (hr) Tableta koja sadrži cetirizin i pseudoefedrin
DE60121048D1 (de) PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE
BR0108980A (pt) Aplicação e formulação farmacêuticas compreendendo inibidor de reabsorção de norepinefrina
BR0007183A (pt) Isonipectoamidas para o tratamento de distúrbios mediados por integrina
BG105984A (bg) Използване на озанетант за приготвяне на лекарствени средства полезни за лечение на разстройства на настроението
ITRM20010136A0 (it) Composti utili per il trattamento di patologie che rispondono all'attivazione del recettore ppar-gamma.
ATE265418T1 (de) Neue substituierte 3-phenoxy- und 3- phenylalkyloxy-2-phenyl-propylamine