SI1161239T1 - 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis - Google Patents

3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis

Info

Publication number
SI1161239T1
SI1161239T1 SI200030586T SI200030586T SI1161239T1 SI 1161239 T1 SI1161239 T1 SI 1161239T1 SI 200030586 T SI200030586 T SI 200030586T SI 200030586 T SI200030586 T SI 200030586T SI 1161239 T1 SI1161239 T1 SI 1161239T1
Authority
SI
Slovenia
Prior art keywords
dichloropyrid
cyclopropylmethoxy
difluoromethoxy
benzamide
treatment
Prior art date
Application number
SI200030586T
Other languages
English (en)
Slovenian (sl)
Inventor
Hermann Amschler
Armin Hatzelmann
Christian Schudt
Hans-Peter Kley
Karl Sanders
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of SI1161239T1 publication Critical patent/SI1161239T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SI200030586T 1999-03-10 2000-03-01 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis SI1161239T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99104793 1999-03-10
PCT/EP2000/001703 WO2000053182A2 (en) 1999-03-10 2000-03-01 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis
EP00910736A EP1161239B1 (en) 1999-03-10 2000-03-01 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
SI1161239T1 true SI1161239T1 (en) 2005-06-30

Family

ID=8237737

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030586T SI1161239T1 (en) 1999-03-10 2000-03-01 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis

Country Status (12)

Country Link
US (1) US6531493B1 (enExample)
EP (1) EP1161239B1 (enExample)
JP (1) JP2002538207A (enExample)
AT (1) ATE279924T1 (enExample)
AU (1) AU3284000A (enExample)
CA (1) CA2364258C (enExample)
DE (1) DE60015098T2 (enExample)
DK (1) DK1161239T3 (enExample)
ES (1) ES2231162T3 (enExample)
PT (1) PT1161239E (enExample)
SI (1) SI1161239T1 (enExample)
WO (1) WO2000053182A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1188438A1 (en) * 2000-09-15 2002-03-20 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production
EP1199074A1 (en) * 2000-09-15 2002-04-24 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production
WO2002088079A2 (en) * 2001-05-01 2002-11-07 Bristol-Myers Squibb Company Dual inhibitors of pde 7 and pde 4
US20030092706A1 (en) * 2001-11-09 2003-05-15 Johannes Barsig Combination
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ES2319517T3 (es) 2002-05-28 2009-05-08 Nycomed Gmbh Preparacion farmaceutica aplicable topicamente.
US6822114B1 (en) 2002-10-08 2004-11-23 Albemarle Corporation Process for production of fluoroalkoxy-substituted benzamides and their intermediates
MXPA04008070A (es) 2003-03-10 2004-11-26 Altana Pharma Ag Novedoso proceso para la preparacion de roflumilasto.
DE102004046235A1 (de) 2004-09-22 2006-03-30 Altana Pharma Ag Arzneimittelzubereitung
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0652868B1 (en) 1992-07-28 2004-11-10 Aventis Pharma Limited INHIBITORS OF c-AMP PHOSPHODIESTERASE
HU220041B (hu) 1993-07-02 2001-10-28 Byk Gulden Lomberg Chemische Fabrik Gmbh. Fluor-alkoxi-helyettesített benzamidszármazékok, eljárás előállításukra és ezeket a vegyületeket tartalmazó gyógyászati készítmények
AU699085B2 (en) * 1994-04-21 1998-11-19 Schering Aktiengesellschaft PDE IV inhibitors for treating Multiple Sclerosis

Also Published As

Publication number Publication date
CA2364258C (en) 2008-12-30
JP2002538207A (ja) 2002-11-12
ATE279924T1 (de) 2004-11-15
EP1161239B1 (en) 2004-10-20
AU3284000A (en) 2000-09-28
US6531493B1 (en) 2003-03-11
EP1161239A2 (en) 2001-12-12
DK1161239T3 (da) 2005-02-14
PT1161239E (pt) 2005-02-28
WO2000053182A3 (en) 2001-04-12
WO2000053182A2 (en) 2000-09-14
ES2231162T3 (es) 2005-05-16
DE60015098D1 (de) 2004-11-25
DE60015098T2 (de) 2006-02-02
CA2364258A1 (en) 2000-09-14

Similar Documents

Publication Publication Date Title
DE60112974D1 (en) Carbolinderivate
BR0009480A (pt) Soluções de poliuretano com unidades de estrutura de alcoxissilano
ZA200107495B (en) N-cyanomethyl amides as protease inhibitors.
YU68002A (sh) Modifikovani faktor viii
MXPA02012712A (es) N-ureidoheterocicloalquil-piperidinas como moduladores de la actividad del receptor de quimiocinas.
AU2003297260A1 (en) Fast-disintegrating solid dosage forms being not friable and comprising pullulan
BG106586A (en) Pyrazolopyramidines as therapeutic agents
DE60236102D1 (en) 1h-indolderivate als hochselektive cyclooxygenase-2-inhibitoren
DK1200418T3 (da) Nematodicide trifluorbutener
MY116027A (en) New use
IL160081A0 (en) Novel 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity
EP1129089A4 (en) SPIRO-INDOLE AS Y5 RECEPTOR ANTAGONISTS
DE60216233D1 (en) Carbolinderivate
MXPA03002911A (es) Compuestos quimicos.
DE60205899D1 (en) 1-biaryl-1,8-naphthyridin-4-one als phosphodieseterase-inhibitoren
SI1161239T1 (en) 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis
ZA971892B (en) Compositions and use of benzamides and nicotin-amides as anti-inflammatory agents
MY133169A (en) Substituted heterocyclic benzocycloalkenes and the use thereof as substances having an analgesic effect
IL154675A0 (en) N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-yl-benzenesulfonamide
MXPA02007903A (es) Uso de acido 2-metil-tiazolidina-2, 4-dicarboxilico (2-mtdc) y/o sales fisiologicamente compatibles para tratar y/o prevenir canceres.
DE69426021D1 (de) Xamonelin-Tartrat
DK0720597T3 (da) Triarylethylenderivater til terapeutisk anvendelse
ATE242763T1 (de) Methoximinophenylessigsäureamide
MXPA04005226A (es) 1,3-diarilprop-2-en-1-onas, composiciones que las contienen y su utilizacion.
NZ516209A (en) Indoloazepines as vasopressin receptor antagonists