JP2002535994A - 標的ｄｎａのインビボ除去による遺伝子修復 - Google Patents

標的ｄｎａのインビボ除去による遺伝子修復

Info

Publication number
JP2002535994A
JP2002535994A JP2000597444A JP2000597444A JP2002535994A JP 2002535994 A JP2002535994 A JP 2002535994A JP 2000597444 A JP2000597444 A JP 2000597444A JP 2000597444 A JP2000597444 A JP 2000597444A JP 2002535994 A JP2002535994 A JP 2002535994A
Authority
JP
Japan
Prior art keywords
dna
vector
restriction endonuclease
target dna
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000597444A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002535994A5 (enExample
Inventor
シューリカ，アンドレ
マリガン，リチャード，シー．
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur filed Critical Institut Pasteur
Publication of JP2002535994A publication Critical patent/JP2002535994A/ja
Publication of JP2002535994A5 publication Critical patent/JP2002535994A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2000597444A 1999-02-03 2000-02-03 標的ｄｎａのインビボ除去による遺伝子修復 Pending JP2002535994A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11847299P 1999-02-03 1999-02-03
US60/118,472 1999-02-03
PCT/US2000/002949 WO2000046385A1 (en) 1999-02-03 2000-02-03 Gene repair involving in vivo excision of targeting dna

Publications (2)

Publication Number Publication Date
JP2002535994A true JP2002535994A (ja) 2002-10-29
JP2002535994A5 JP2002535994A5 (enExample) 2007-04-05

Family

ID=22378818

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000597444A Pending JP2002535994A (ja) 1999-02-03 2000-02-03 標的ｄｎａのインビボ除去による遺伝子修復

Country Status (6)

Country Link
US (4) US20020110898A1 (enExample)
EP (1) EP1151124A1 (enExample)
JP (1) JP2002535994A (enExample)
AU (1) AU2982300A (enExample)
CA (1) CA2360878A1 (enExample)
WO (1) WO2000046385A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006518372A (ja) * 2003-01-28 2006-08-10 セレクティス 脊椎動物の体組織においてエクスビボかつイントトで相同的組換えを誘発するためのメガヌクレアーゼの使用およびその応用

Families Citing this family (24)

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US7102055B1 (en) * 1997-11-18 2006-09-05 Pioneer Hi-Bred International, Inc. Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant
ATE401410T1 (de) * 1997-11-18 2008-08-15 Pioneer Hi Bred Int Zusammensetzungen und verfahren für die genetische modifizierung von pflanzen
CA2360878A1 (en) * 1999-02-03 2000-08-10 The Children's Medical Center Corporation Gene repair involving excision of targeting dna
WO2000046386A2 (en) 1999-02-03 2000-08-10 The Children's Medical Center Corporation Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site
ATE447967T1 (de) 2001-09-14 2009-11-15 Cytos Biotechnology Ag Verpackung von immunstimulierendem cpg in virusähnlichen partikeln: herstellungsverfahren und verwendung
WO2003087341A2 (en) 2002-01-23 2003-10-23 The University Of Utah Research Foundation Targeted chromosomal mutagenesis using zinc finger nucleases
WO2003078619A1 (en) 2002-03-15 2003-09-25 Cellectis Hybrid and single chain meganucleases and use thereof
WO2009095742A1 (en) 2008-01-31 2009-08-06 Cellectis New i-crei derived single-chain meganuclease and uses thereof
US20030232410A1 (en) * 2002-03-21 2003-12-18 Monika Liljedahl Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
JP2006502748A (ja) 2002-09-05 2006-01-26 カリフォルニア インスティテュート オブ テクノロジー 遺伝子ターゲッティングを誘発するキメラヌクレアーゼの使用方法
US8409861B2 (en) 2003-08-08 2013-04-02 Sangamo Biosciences, Inc. Targeted deletion of cellular DNA sequences
US7888121B2 (en) 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
US20120196370A1 (en) 2010-12-03 2012-08-02 Fyodor Urnov Methods and compositions for targeted genomic deletion
US11311574B2 (en) 2003-08-08 2022-04-26 Sangamo Therapeutics, Inc. Methods and compositions for targeted cleavage and recombination
US7972854B2 (en) 2004-02-05 2011-07-05 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
CA2615797C (en) 2005-07-18 2014-04-29 Pioneer Hi-Bred International, Inc. Modified frt recombination sites and methods of use
ES2626025T3 (es) 2005-10-18 2017-07-21 Precision Biosciences Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas
US7852247B2 (en) * 2006-12-05 2010-12-14 Texas Instruments Incorporated Mixed-signal filter
WO2009006297A2 (en) * 2007-06-29 2009-01-08 Pioneer Hi-Bred International, Inc. Methods for altering the genome of a monocot plant cell
AU2008335324A1 (en) * 2007-12-07 2009-06-18 Precision Biosciences, Inc. Rationally-designed meganucleases with recognition sequences found in DNase hypersensitive regions of the human genome
WO2009114321A2 (en) * 2008-03-11 2009-09-17 Precision Biosciencs, Inc. Rationally-designed meganucleases for maize genome engineering
US20100071083A1 (en) * 2008-03-12 2010-03-18 Smith James J Temperature-dependent meganuclease activity
JP2011519558A (ja) * 2008-04-28 2011-07-14 プレシジョン バイオサイエンシズ，インク． 合理的に設計されたｄｎａ結合タンパク質とエフェクタードメインとの融合分子
DK2313498T3 (en) 2008-07-14 2017-05-22 Prec Biosciences Inc RECOGNITION SEQUENCES FOR I-CREI-DERIVED MECHANUCLEASES AND APPLICATIONS THEREOF

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10508478A (ja) * 1994-11-07 1998-08-25 アンスティテュ・パストゥール Ｉ−Ｓｃｅ Ｉ酵素をコードするヌクレオチド配列、及びその使用
US5830729A (en) * 1996-04-18 1998-11-03 Institut Pasteur I Sce I-induced gene replacement and gene conversion in embryonic stem cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US285538A (en) * 1883-09-25 Ore-crusher
US5436150A (en) 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
US5474896A (en) 1992-05-05 1995-12-12 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
ATE178654T1 (de) 1993-12-20 1999-04-15 Akzo Nobel Nv Impstoff zum schutze von pferden gegen pferdeherpesvirus-infektionen
CA2360878A1 (en) 1999-02-03 2000-08-10 The Children's Medical Center Corporation Gene repair involving excision of targeting dna
WO2000046386A2 (en) 1999-02-03 2000-08-10 The Children's Medical Center Corporation Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site
DK1427828T3 (da) * 2001-09-14 2010-07-19 Cellectis Tilfældig integration af et polynucleotid efter in vivo-linearisering
JP3915752B2 (ja) * 2003-07-25 2007-05-16 船井電機株式会社 デジタル情報記録装置およびそれを備える映像記録再生装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10508478A (ja) * 1994-11-07 1998-08-25 アンスティテュ・パストゥール Ｉ−Ｓｃｅ Ｉ酵素をコードするヌクレオチド配列、及びその使用
US5830729A (en) * 1996-04-18 1998-11-03 Institut Pasteur I Sce I-induced gene replacement and gene conversion in embryonic stem cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN5002003148, ＣＯＨＥＮ−ＴＡＮＮＯＵＤＪＩ Ｍ, ＭＯＬＥＣＵＬＡＲ ＡＮＤ ＣＥＬＬＵＬＡＲ ＢＩＯＬＯＧＹ, 199803, Ｖ１８ Ｎ３, Ｐ１４４４−１４４８ *
JPN5002003149, ＣＨＯＵＬＩＫＡ Ａ, ＭＯＬＥＣＵＬＡＲ ＡＮＤ ＣＥＬＬＵＬＡＲ ＢＩＯＬＯＧＹ, 199504, Ｖ１５ Ｎ４, Ｐ１９６８−１９７３, US *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006518372A (ja) * 2003-01-28 2006-08-10 セレクティス 脊椎動物の体組織においてエクスビボかつイントトで相同的組換えを誘発するためのメガヌクレアーゼの使用およびその応用

Also Published As

Publication number Publication date
US20090060896A1 (en) 2009-03-05
CA2360878A1 (en) 2000-08-10
EP1151124A1 (en) 2001-11-07
US7285538B2 (en) 2007-10-23
US7960525B2 (en) 2011-06-14
US20120165400A1 (en) 2012-06-28
AU2982300A (en) 2000-08-25
US20030229039A1 (en) 2003-12-11
WO2000046385A1 (en) 2000-08-10
US20020110898A1 (en) 2002-08-15

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