JP2002535994A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002535994A5 JP2002535994A5 JP2000597444A JP2000597444A JP2002535994A5 JP 2002535994 A5 JP2002535994 A5 JP 2002535994A5 JP 2000597444 A JP2000597444 A JP 2000597444A JP 2000597444 A JP2000597444 A JP 2000597444A JP 2002535994 A5 JP2002535994 A5 JP 2002535994A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- vector
- restriction endonuclease
- target
- introducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091008146 restriction endonucleases Proteins 0.000 description 41
- 239000013598 vector Substances 0.000 description 41
- 238000000034 method Methods 0.000 description 22
- 239000013611 chromosomal DNA Substances 0.000 description 20
- 108090000623 proteins and genes Proteins 0.000 description 12
- 108020004707 nucleic acids Proteins 0.000 description 9
- 150000007523 nucleic acids Chemical class 0.000 description 9
- 102000039446 nucleic acids Human genes 0.000 description 9
- 230000006798 recombination Effects 0.000 description 9
- 238000005215 recombination Methods 0.000 description 9
- 230000035772 mutation Effects 0.000 description 5
- 230000008439 repair process Effects 0.000 description 4
- 238000013518 transcription Methods 0.000 description 3
- 230000035897 transcription Effects 0.000 description 3
- 239000013603 viral vector Substances 0.000 description 3
- 241000700605 Viruses Species 0.000 description 2
- 239000013612 plasmid Substances 0.000 description 2
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000002715 modification method Methods 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11847299P | 1999-02-03 | 1999-02-03 | |
| US60/118,472 | 1999-02-03 | ||
| PCT/US2000/002949 WO2000046385A1 (en) | 1999-02-03 | 2000-02-03 | Gene repair involving in vivo excision of targeting dna |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002535994A JP2002535994A (ja) | 2002-10-29 |
| JP2002535994A5 true JP2002535994A5 (enExample) | 2007-04-05 |
Family
ID=22378818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000597444A Pending JP2002535994A (ja) | 1999-02-03 | 2000-02-03 | 標的ｄｎａのインビボ除去による遺伝子修復 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20020110898A1 (enExample) |
| EP (1) | EP1151124A1 (enExample) |
| JP (1) | JP2002535994A (enExample) |
| AU (1) | AU2982300A (enExample) |
| CA (1) | CA2360878A1 (enExample) |
| WO (1) | WO2000046385A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7102055B1 (en) * | 1997-11-18 | 2006-09-05 | Pioneer Hi-Bred International, Inc. | Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant |
| ATE401410T1 (de) * | 1997-11-18 | 2008-08-15 | Pioneer Hi Bred Int | Zusammensetzungen und verfahren für die genetische modifizierung von pflanzen |
| CA2360878A1 (en) * | 1999-02-03 | 2000-08-10 | The Children's Medical Center Corporation | Gene repair involving excision of targeting dna |
| WO2000046386A2 (en) | 1999-02-03 | 2000-08-10 | The Children's Medical Center Corporation | Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site |
| ATE447967T1 (de) | 2001-09-14 | 2009-11-15 | Cytos Biotechnology Ag | Verpackung von immunstimulierendem cpg in virusähnlichen partikeln: herstellungsverfahren und verwendung |
| WO2003087341A2 (en) | 2002-01-23 | 2003-10-23 | The University Of Utah Research Foundation | Targeted chromosomal mutagenesis using zinc finger nucleases |
| WO2003078619A1 (en) | 2002-03-15 | 2003-09-25 | Cellectis | Hybrid and single chain meganucleases and use thereof |
| WO2009095742A1 (en) | 2008-01-31 | 2009-08-06 | Cellectis | New i-crei derived single-chain meganuclease and uses thereof |
| US20030232410A1 (en) * | 2002-03-21 | 2003-12-18 | Monika Liljedahl | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| JP2006502748A (ja) | 2002-09-05 | 2006-01-26 | カリフォルニア インスティテュート オブ テクノロジー | 遺伝子ターゲッティングを誘発するキメラヌクレアーゼの使用方法 |
| EP1590468A2 (en) | 2003-01-28 | 2005-11-02 | Cellectis | Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof |
| US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US20120196370A1 (en) | 2010-12-03 | 2012-08-02 | Fyodor Urnov | Methods and compositions for targeted genomic deletion |
| US11311574B2 (en) | 2003-08-08 | 2022-04-26 | Sangamo Therapeutics, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| CA2615797C (en) | 2005-07-18 | 2014-04-29 | Pioneer Hi-Bred International, Inc. | Modified frt recombination sites and methods of use |
| ES2626025T3 (es) | 2005-10-18 | 2017-07-21 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| US7852247B2 (en) * | 2006-12-05 | 2010-12-14 | Texas Instruments Incorporated | Mixed-signal filter |
| WO2009006297A2 (en) * | 2007-06-29 | 2009-01-08 | Pioneer Hi-Bred International, Inc. | Methods for altering the genome of a monocot plant cell |
| AU2008335324A1 (en) * | 2007-12-07 | 2009-06-18 | Precision Biosciences, Inc. | Rationally-designed meganucleases with recognition sequences found in DNase hypersensitive regions of the human genome |
| WO2009114321A2 (en) * | 2008-03-11 | 2009-09-17 | Precision Biosciencs, Inc. | Rationally-designed meganucleases for maize genome engineering |
| US20100071083A1 (en) * | 2008-03-12 | 2010-03-18 | Smith James J | Temperature-dependent meganuclease activity |
| JP2011519558A (ja) * | 2008-04-28 | 2011-07-14 | プレシジョン バイオサイエンシズ，インク． | 合理的に設計されたｄｎａ結合タンパク質とエフェクタードメインとの融合分子 |
| DK2313498T3 (en) | 2008-07-14 | 2017-05-22 | Prec Biosciences Inc | RECOGNITION SEQUENCES FOR I-CREI-DERIVED MECHANUCLEASES AND APPLICATIONS THEREOF |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US285538A (en) * | 1883-09-25 | Ore-crusher | ||
| US5436150A (en) | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5474896A (en) | 1992-05-05 | 1995-12-12 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| US5792632A (en) * | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| ATE178654T1 (de) | 1993-12-20 | 1999-04-15 | Akzo Nobel Nv | Impstoff zum schutze von pferden gegen pferdeherpesvirus-infektionen |
| US5830729A (en) * | 1996-04-18 | 1998-11-03 | Institut Pasteur | I Sce I-induced gene replacement and gene conversion in embryonic stem cells |
| CA2360878A1 (en) | 1999-02-03 | 2000-08-10 | The Children's Medical Center Corporation | Gene repair involving excision of targeting dna |
| WO2000046386A2 (en) | 1999-02-03 | 2000-08-10 | The Children's Medical Center Corporation | Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site |
| DK1427828T3 (da) * | 2001-09-14 | 2010-07-19 | Cellectis | Tilfældig integration af et polynucleotid efter in vivo-linearisering |
| JP3915752B2 (ja) * | 2003-07-25 | 2007-05-16 | 船井電機株式会社 | デジタル情報記録装置およびそれを備える映像記録再生装置 |
-
2000
- 2000-02-03 CA CA002360878A patent/CA2360878A1/en not_active Abandoned
- 2000-02-03 JP JP2000597444A patent/JP2002535994A/ja active Pending
- 2000-02-03 EP EP00908491A patent/EP1151124A1/en not_active Ceased
- 2000-02-03 AU AU29823/00A patent/AU2982300A/en not_active Abandoned
- 2000-02-03 WO PCT/US2000/002949 patent/WO2000046385A1/en not_active Ceased
-
2001
- 2001-08-03 US US09/922,495 patent/US20020110898A1/en not_active Abandoned
-
2003
- 2003-01-02 US US10/336,069 patent/US7285538B2/en not_active Expired - Lifetime
-
2007
- 2007-09-25 US US11/904,034 patent/US7960525B2/en not_active Expired - Fee Related
-
2011
- 2011-05-05 US US13/101,463 patent/US20120165400A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002535994A5 (enExample) | ||
| Manghwar et al. | CRISPR/Cas systems in genome editing: methodologies and tools for sgRNA design, off‐target evaluation, and strategies to mitigate off‐target effects | |
| Choulika et al. | Induction of homologous recombination in mammalian chromosomes by using the I-Sce I system of Saccharomyces cerevisiae | |
| Hamilton et al. | Construction of tomato genomic DNA libraries in a binary‐BAC (BIBAC) vector | |
| Ren et al. | Bidirectional promoter-based CRISPR-Cas9 systems for plant genome editing | |
| US20210380983A1 (en) | ENGINEERING PLANT GENOMES USING CRISPR/Cas SYSTEMS | |
| CN114075559B (zh) | 一种2型CRISPR/Cas9基因编辑系统及其应用 | |
| JP2002535995A5 (enExample) | ||
| JP4689940B2 (ja) | ヘテロ二本鎖の相補性を増大させる方法 | |
| DE69943389D1 (de) | Verfahren und mittel zum erhalt von veränderten phänotypen | |
| CA2851807A1 (en) | Nucleic acid construct containing full length genome of human hepatitis c virus, recombinant full length virus genome-replicating cells having the nucleic acid construct transferred thereinto and method of producing hepatitis c virus particle | |
| CN113874503A (zh) | 用于调节crispr活性的系统和方法 | |
| CN107686842A (zh) | 一种靶多核苷酸编辑方法及其应用 | |
| CN115786304A (zh) | 一种Cas12a蛋白突变体、含有其的碱基编辑器和应用 | |
| JPWO2020014577A5 (enExample) | ||
| CN103757053A (zh) | 一种特异性的dna病毒基因组定点改造及筛选方法 | |
| JP2006508665A5 (enExample) | ||
| KR102679001B1 (ko) | 신규의 개량된 염기 편집 또는 교정용 융합단백질 및 이의 용도 | |
| CN105861485A (zh) | 一种提高基因置换效率的方法 | |
| US20230265421A1 (en) | Type ii crispr/cas9 genome editing system and the application thereof | |
| Badge et al. | The role of host factors in the population dynamics of selfish transposable elements | |
| Riederer et al. | The mode of cauliflower mosaic virus propagation in the plant allows rapid amplification of viable mutant strains | |
| US20030087254A1 (en) | Methods for the preparation of polynucleotide libraries and identification of library members having desired characteristics | |
| Jamsai et al. | Insertion of modifications in the β-globin locus using GET recombination with single-stranded oligonucleotides and denatured PCR fragments | |
| US7303897B2 (en) | Method of preparing polynucleotide fragments for use in shuffling, and shuffling of same |