JP2002535450A5 - - Google Patents
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- Publication number
- JP2002535450A5 JP2002535450A5 JP2000594947A JP2000594947A JP2002535450A5 JP 2002535450 A5 JP2002535450 A5 JP 2002535450A5 JP 2000594947 A JP2000594947 A JP 2000594947A JP 2000594947 A JP2000594947 A JP 2000594947A JP 2002535450 A5 JP2002535450 A5 JP 2002535450A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- monolayer
- sample
- molecules
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 description 27
- 239000000523 sample Substances 0.000 description 16
- 239000002356 single layer Substances 0.000 description 16
- 238000000034 method Methods 0.000 description 12
- 125000000524 functional group Chemical group 0.000 description 8
- 102000039446 nucleic acids Human genes 0.000 description 7
- 108020004707 nucleic acids Proteins 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 239000010410 layer Substances 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 3
- 239000003999 initiator Substances 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 150000008365 aromatic ketones Chemical class 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 239000003505 polymerization initiator Substances 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 150000003923 2,5-pyrrolediones Chemical class 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- WHNPOQXWAMXPTA-UHFFFAOYSA-N 3-methylbut-2-enamide Chemical compound CC(C)=CC(N)=O WHNPOQXWAMXPTA-UHFFFAOYSA-N 0.000 description 1
- 239000005046 Chlorosilane Substances 0.000 description 1
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- NQTADLQHYWFPDB-UHFFFAOYSA-N N-Hydroxysuccinimide Chemical class ON1C(=O)CCC1=O NQTADLQHYWFPDB-UHFFFAOYSA-N 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- -1 alkoxysilane Chemical compound 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 150000001540 azides Chemical class 0.000 description 1
- 125000000751 azo group Chemical group [*]N=N[*] 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- KOPOQZFJUQMUML-UHFFFAOYSA-N chlorosilane Chemical compound Cl[SiH3] KOPOQZFJUQMUML-UHFFFAOYSA-N 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 150000002118 epoxides Chemical class 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- 150000002540 isothiocyanates Chemical class 0.000 description 1
- 125000000468 ketone group Chemical group 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 238000001668 nucleic acid synthesis Methods 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99101340 | 1999-01-25 | ||
| EP99104278.9 | 1999-03-03 | ||
| EP99104278A EP1035218A1 (en) | 1999-03-03 | 1999-03-03 | Immobilization of molecules on surfaces via polymer brushes |
| EP99101340.0 | 1999-03-03 | ||
| PCT/EP2000/000554 WO2000043539A2 (en) | 1999-01-25 | 2000-01-25 | Immobilization of molecules on surfaces via polymer brushes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002535450A JP2002535450A (ja) | 2002-10-22 |
| JP2002535450A5 true JP2002535450A5 (enExample) | 2007-02-22 |
| JP4970654B2 JP4970654B2 (ja) | 2012-07-11 |
Family
ID=26152863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000594947A Expired - Fee Related JP4970654B2 (ja) | 1999-01-25 | 2000-01-25 | ポリマーブラシを介する表面上での分子の固定化 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7250253B1 (enExample) |
| EP (1) | EP1144677B1 (enExample) |
| JP (1) | JP4970654B2 (enExample) |
| AT (1) | ATE334226T1 (enExample) |
| AU (1) | AU3150400A (enExample) |
| CA (1) | CA2360027A1 (enExample) |
| DE (1) | DE60029561T2 (enExample) |
| WO (1) | WO2000043539A2 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60027309T2 (de) | 1999-07-02 | 2006-08-31 | Symyx Technologies, Inc., Santa Clara | Polymerverzweigungen zur immobilisierung von molekülen auf oberflächen oder substraten, wobei die polymere wasserlösliche oder wasserdispergierbare segmente und sonden aufweisen |
| AU6075900A (en) * | 1999-07-07 | 2001-01-22 | Mirus Corporation | Substrates for nucleic acid immobilization onto solid supports |
| CA2317179A1 (en) * | 1999-09-01 | 2001-03-01 | Affymetrix, Inc. | Macromolecular arrays on polymeric brushes and methods for preparing the same |
| FR2802550B1 (fr) * | 1999-12-17 | 2004-03-05 | Centre Nat Rech Scient | Biopuces, preparation et utilisations |
| EP1176423B1 (en) * | 2000-07-27 | 2007-02-28 | Micronas Holding GmbH | Surface-attached polyfunctional polymer networks for sensor chips |
| ATE316581T1 (de) | 2000-09-05 | 2006-02-15 | Zeltz Patrick Dr | Verfahren zur spezifischen bestimmung von dna- sequenzen mittels paralleler amplifikation |
| DE60033665T2 (de) * | 2000-10-31 | 2007-10-31 | Micronas Gmbh | Gemusterte Polymeroberflächen geeignet für Biokonjugationen und Verfahren zu ihrer Herstellung |
| US7205161B2 (en) | 2001-01-10 | 2007-04-17 | Symyx Technologies, Inc. | Polymer brushes for immobilizing molecules to a surface or substrate having improved stability |
| US20030068317A1 (en) * | 2001-04-20 | 2003-04-10 | William Lee | High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon |
| AU2002367825A1 (en) * | 2001-07-30 | 2003-10-13 | Sts Biopolymers, Inc. | Graft polymer matrices |
| US20040253596A1 (en) * | 2001-08-27 | 2004-12-16 | Michael Pawlak | Bioanalytical recognition surface with optimized recognition element density |
| US6867295B2 (en) | 2001-09-07 | 2005-03-15 | Dionex Corporation | Ion exchange cryptands covalently bound to substrates |
| WO2003049671A2 (en) * | 2001-12-10 | 2003-06-19 | Emembrane, Inc. | Functionalized materials and libraries thereof |
| JP2003294742A (ja) * | 2002-03-29 | 2003-10-15 | Inst Of Physical & Chemical Res | ハイブリダイゼーション用基板及びその使用方法 |
| EP1527202A1 (de) * | 2002-08-08 | 2005-05-04 | Siemens Aktiengesellschaft | Erkennungsschichten aus hydrogel auf der basis von polyacrylamid für die biosensorik |
| WO2004014969A1 (en) * | 2002-08-09 | 2004-02-19 | Ottawa Health Research Institute | Bio-synthetic matrix and uses thereof |
| AU2003270769A1 (en) * | 2002-09-18 | 2004-04-08 | Emembrane, Inc. | Functionalized materials and methods of using same |
| DE10245435B4 (de) | 2002-09-27 | 2006-03-16 | Micronas Gmbh | Vorrichtung zur Detektion mindestens eines in einer zu untersuchenden Probe enthaltenen Liganden |
| DE10328730B4 (de) * | 2003-06-25 | 2006-08-17 | Micronas Gmbh | Verfahren zum Herstellen eines Microarrays und Vorrichtung zum Versehen eines Trägers für ein Microarray mit Beschichtungsstoffen |
| US7354706B2 (en) | 2003-09-09 | 2008-04-08 | The Regents Of The University Of Colorado, A Body Corporate | Use of photopolymerization for amplification and detection of a molecular recognition event |
| US20090163375A1 (en) | 2003-09-09 | 2009-06-25 | Bowman Christopher N | Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event |
| DE102004010430A1 (de) | 2004-03-01 | 2005-09-22 | Rühe, Jürgen, Prof. Dr. | Verfahren zur kovalenten Immobilisierung von Biomolekülen an organischen Oberflächen |
| US7514764B2 (en) | 2005-03-23 | 2009-04-07 | Wisconsin Alumni Research Foundation | Materials and methods for creating imaging layers |
| DE102005022782A1 (de) | 2005-05-12 | 2006-11-16 | Tesa Ag | Haftklebemassen und Verfahren zu deren Herstellung |
| WO2006128644A1 (en) * | 2005-05-30 | 2006-12-07 | Giovanna Pirri | Polymer coating and functionalization of solid surfaces |
| US8357433B2 (en) | 2005-06-14 | 2013-01-22 | Siemens Energy, Inc. | Polymer brushes |
| US7862886B2 (en) * | 2005-08-12 | 2011-01-04 | Fujifilm Corporation | Optical film, antireflection film, processes for producing the same, and polarizing plate and display employing the same |
| EP1811300B1 (de) | 2005-12-23 | 2008-11-12 | Micronas GmbH | Sensorchip mit in einem Polymer-Netzwerk eingelagerten Rezeptoren |
| KR100838124B1 (ko) * | 2007-02-01 | 2008-06-13 | 포항공과대학교 산학협력단 | 생체적합성 지방족 브러쉬 고분자 및 그 제조 방법 |
| DE102008032570A1 (de) | 2008-07-11 | 2010-01-14 | Tesa Se | Haftklebemassen und Verfahren zu deren Herstellung |
| EP2192409B1 (en) | 2008-11-26 | 2014-04-23 | Corning Incorporated | Label independent detection biosensor composition and methods thereof |
| DE102009060626A1 (de) | 2009-12-24 | 2011-06-30 | Klapproth, Holger, Dr., 79108 | Kalibrierte Flusszelle zur IR-Analytik |
| US20130199692A1 (en) * | 2010-07-30 | 2013-08-08 | North Carolina State University | Surface Functionalization of Polyester |
| AP2013007092A0 (en) | 2011-02-01 | 2013-09-30 | Maharshi Dayanand University | Polyvinyl chloride surface co-immobilized with enzymes and uses thereof |
| EP2718691B1 (de) | 2011-06-09 | 2017-12-13 | QFood GmbH | Verfahren und vorrichtung zum bestimmen der konzentration eines in einer flüssigen probe enthaltenen analyten |
| MY178616A (en) | 2012-09-17 | 2020-10-19 | Grace W R & Co | Chromatography media and devices |
| MY195756A (en) | 2012-09-17 | 2023-02-09 | Grace W R & Co | Functionalized Particulate Support Material and Methods of Making and Using the Same |
| EP2998326B1 (en) | 2013-05-13 | 2020-02-19 | Japan Science and Technology Agency | Novel composite material, and polymer coating material precursor produced using same |
| CN111118121B (zh) | 2013-12-05 | 2024-07-19 | 生捷科技控股公司 | 图案化阵列的制备 |
| CN105940024B (zh) | 2013-12-05 | 2019-03-15 | 生捷科技控股公司 | 修饰的表面 |
| CN107002117B (zh) | 2013-12-05 | 2021-12-10 | 生捷科技控股公司 | 核酸测序方法 |
| JP6853670B2 (ja) | 2014-01-16 | 2021-04-07 | ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ | 親和性クロマトグラフィー媒体及びクロマトグラフィーデバイス |
| US11060139B2 (en) | 2014-03-28 | 2021-07-13 | Centrillion Technology Holdings Corporation | Methods for sequencing nucleic acids |
| JP6914189B2 (ja) | 2014-05-02 | 2021-08-04 | ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ | 官能化担体材料並びに官能化担体材料を作製及び使用する方法 |
| CN107921407B (zh) | 2015-06-05 | 2022-07-05 | 格雷斯公司 | 生物处理吸附澄清剂及其制备和使用方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63233360A (ja) * | 1986-12-15 | 1988-09-29 | Fuji Photo Film Co Ltd | 電気泳動用媒体 |
| SE8801070D0 (sv) * | 1988-03-23 | 1988-03-23 | Pharmacia Ab | Method for immobilizing a dna sequence on a solid support |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| JPH05502585A (ja) * | 1989-12-04 | 1993-05-13 | ベクトン ディッキンソン アンド カンパニー | ポリマーに共有結合したオリゴヌクレオチドの利用により向上される標的核酸の捕獲 |
| WO1993009250A1 (en) * | 1991-11-01 | 1993-05-13 | Adelaide Children's Hospital | Solid phase amplification process |
| US5624711A (en) * | 1995-04-27 | 1997-04-29 | Affymax Technologies, N.V. | Derivatization of solid supports and methods for oligomer synthesis |
| SE9502608D0 (sv) | 1995-07-14 | 1995-07-14 | Pharmacia Biosensor Ab | Method for nucleic acid senquencing |
| JP2001508281A (ja) * | 1995-11-14 | 2001-06-26 | ベイラー カレッジ オブ メディシン | 活性表面化学特性に基づく統合核酸ハイブリダイゼーション装置 |
| US6132765A (en) * | 1996-04-12 | 2000-10-17 | Uroteq Inc. | Drug delivery via therapeutic hydrogels |
| EP1005644B1 (en) * | 1996-04-25 | 2003-03-12 | Pence, Inc. | Biosensor device and method |
| US6130037A (en) * | 1996-04-25 | 2000-10-10 | Pence And Mcgill University | Biosensor device and method |
| US6485703B1 (en) * | 1998-07-31 | 2002-11-26 | The Texas A&M University System | Compositions and methods for analyte detection |
| JP3919958B2 (ja) * | 1998-11-11 | 2007-05-30 | 独立行政法人科学技術振興機構 | 高分子薄膜の製造方法 |
| DE69924749T2 (de) * | 1998-11-20 | 2006-04-27 | The University Of Connecticut, Farmington | Generisch integrierte implantierbare Potentiostatfernmeßanordnung für elektrochemische Fühler |
| US6413587B1 (en) * | 1999-03-02 | 2002-07-02 | International Business Machines Corporation | Method for forming polymer brush pattern on a substrate surface |
-
2000
- 2000-01-25 DE DE60029561T patent/DE60029561T2/de not_active Expired - Lifetime
- 2000-01-25 WO PCT/EP2000/000554 patent/WO2000043539A2/en not_active Ceased
- 2000-01-25 US US09/889,935 patent/US7250253B1/en not_active Expired - Fee Related
- 2000-01-25 EP EP00909103A patent/EP1144677B1/en not_active Expired - Lifetime
- 2000-01-25 CA CA002360027A patent/CA2360027A1/en not_active Abandoned
- 2000-01-25 AT AT00909103T patent/ATE334226T1/de not_active IP Right Cessation
- 2000-01-25 JP JP2000594947A patent/JP4970654B2/ja not_active Expired - Fee Related
- 2000-01-25 AU AU31504/00A patent/AU3150400A/en not_active Abandoned
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