JP2002535407A5 - - Google Patents
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- Publication number
- JP2002535407A5 JP2002535407A5 JP2000596008A JP2000596008A JP2002535407A5 JP 2002535407 A5 JP2002535407 A5 JP 2002535407A5 JP 2000596008 A JP2000596008 A JP 2000596008A JP 2000596008 A JP2000596008 A JP 2000596008A JP 2002535407 A5 JP2002535407 A5 JP 2002535407A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- formula
- acceptable salt
- triazolo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9901743.6A GB9901743D0 (en) | 1999-01-27 | 1999-01-27 | Therapeutic agents |
| GB9901743.6 | 1999-01-27 | ||
| GB9901744.4 | 1999-01-27 | ||
| GBGB9901744.4A GB9901744D0 (en) | 1999-01-27 | 1999-01-27 | Therapeutic agents |
| GB9912429.9 | 1999-05-27 | ||
| GBGB9912429.9A GB9912429D0 (en) | 1999-05-27 | 1999-05-27 | Therapeutic agents |
| PCT/GB2000/000183 WO2000044752A1 (en) | 1999-01-27 | 2000-01-19 | Triazolo-pyridazine derivatives as ligands for gaba receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002535407A JP2002535407A (ja) | 2002-10-22 |
| JP2002535407A5 true JP2002535407A5 (https=) | 2007-03-08 |
Family
ID=27269629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000596008A Withdrawn JP2002535407A (ja) | 1999-01-27 | 2000-01-19 | Ｇａｂａ受容体のリガンドとしてのトリアゾロピリダジン誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6500828B1 (https=) |
| EP (1) | EP1149102B1 (https=) |
| JP (1) | JP2002535407A (https=) |
| AT (1) | ATE284403T1 (https=) |
| AU (1) | AU772947B2 (https=) |
| CA (1) | CA2359008C (https=) |
| DE (1) | DE60016566T2 (https=) |
| ES (1) | ES2232416T3 (https=) |
| WO (1) | WO2000044752A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0000564D0 (en) * | 2000-01-11 | 2000-03-01 | Merck Sharp & Dohme | Therapeutic agents |
| US6958334B2 (en) | 2001-04-10 | 2005-10-25 | Merck & Co., Inc. | Inhibitors of Akt activity |
| WO2002083139A1 (en) | 2001-04-10 | 2002-10-24 | Merck & Co., Inc. | Inhibitors of akt activity |
| US6960584B2 (en) | 2001-04-10 | 2005-11-01 | Merck & Co., Inc. | Inhibitors of Akt activity |
| WO2004048980A1 (en) * | 2002-11-28 | 2004-06-10 | Neurosearch A/S | Method for screening for compounds as potential sedatives or anxiolytics |
| WO2006061428A2 (en) * | 2004-12-10 | 2006-06-15 | Universität Zürich | Gaba-a alpha 2 and alpha 3 receptor agonists for treating neuropathic, inflammatory and migraine associated pain |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| JP2009536667A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | ５ｈｔ受容体介在性の神経新生 |
| EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| CN104098578A (zh) * | 2008-08-29 | 2014-10-15 | 康瑟特制药公司 | 取代的三唑并哒嗪衍生物 |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| JP2012531419A (ja) | 2009-06-23 | 2012-12-10 | コンサート ファーマシューティカルズ インコーポレイテッド | Ｇａｂａ−ａ受容体修飾物質としての重水素修飾されたトリアゾロピリダジン誘導体 |
| WO2011047315A1 (en) | 2009-10-15 | 2011-04-21 | Concert Pharmaceuticals, Inc. | Subsitituted benzimidazoles |
| US20150158870A1 (en) * | 2012-05-11 | 2015-06-11 | Concert Pharmaceuticals Inc. | Polymorphs of 7-(tert-butyl-d9)-3-(2,5-difluorophenyl)-6-((1-methyl-1h-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine |
| US20150099753A1 (en) * | 2012-05-11 | 2015-04-09 | Concert Pharmaceuticals Inc. | Form 5 polymorph of 7-(tert-butyl-d9)-3-(2,5-difluorophenyl)-6-((1-methyl-1h-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine |
| WO2013170242A1 (en) * | 2012-05-11 | 2013-11-14 | Concert Pharmaceuticals, Inc. | Form 2 polymorph of 7-(tert-butyl-d9)-3-(2,5-difluorophenyl)-6-((1-methyl-1h-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine |
| WO2015095549A1 (en) * | 2013-12-18 | 2015-06-25 | Concert Pharmaceuticals, Inc. | Dosage regimen for gabaa receptor subtype selective drug |
| BR112021004661A2 (pt) * | 2018-09-13 | 2021-06-01 | Saniona A/S | composto, composição farmacêutica, método para tratamento de dor neuropática e/ou prurido, e, uso do composto |
| EP4511025A4 (en) * | 2022-04-20 | 2026-04-15 | Engrail Therapeutics Inc | GABAa receptor modulator salts, particles, and their uses |
| CN115837022B (zh) * | 2023-02-20 | 2023-04-25 | 中山大学附属第八医院（深圳福田） | 1,2,4三唑并4,3-b哒嗪衍生物在制备抗衰老药物中的应用 |
| WO2025141131A1 (en) | 2023-12-27 | 2025-07-03 | Saniona A/S | A gabaa receptor ligand and the use thereof in medicine, in particular in the treatment of epilepsy |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000029548A (ko) * | 1996-07-25 | 2000-05-25 | 더블유. 지. 콜 | 가바수용체에대한리간드로서의치환된트리아졸로-피리다진유도체 |
-
2000
- 2000-01-19 AT AT00900748T patent/ATE284403T1/de not_active IP Right Cessation
- 2000-01-19 WO PCT/GB2000/000183 patent/WO2000044752A1/en not_active Ceased
- 2000-01-19 JP JP2000596008A patent/JP2002535407A/ja not_active Withdrawn
- 2000-01-19 AU AU30669/00A patent/AU772947B2/en not_active Ceased
- 2000-01-19 DE DE60016566T patent/DE60016566T2/de not_active Expired - Fee Related
- 2000-01-19 CA CA002359008A patent/CA2359008C/en not_active Expired - Fee Related
- 2000-01-19 EP EP00900748A patent/EP1149102B1/en not_active Expired - Lifetime
- 2000-01-19 ES ES00900748T patent/ES2232416T3/es not_active Expired - Lifetime
- 2000-01-19 US US09/890,000 patent/US6500828B1/en not_active Expired - Fee Related
-
2002
- 2002-12-20 US US10/324,968 patent/US20030158203A1/en not_active Abandoned
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