JP2002533326A5 - - Google Patents
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- Publication number
- JP2002533326A5 JP2002533326A5 JP2000589516A JP2000589516A JP2002533326A5 JP 2002533326 A5 JP2002533326 A5 JP 2002533326A5 JP 2000589516 A JP2000589516 A JP 2000589516A JP 2000589516 A JP2000589516 A JP 2000589516A JP 2002533326 A5 JP2002533326 A5 JP 2002533326A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- oxy
- phenyl
- acetyl
- propanoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C1OC1N(*)C(*)(*)C(N[C@@](Cc(cc1)ccc1OC1OC1N(*)*)C(O*)=O)=O Chemical compound *C1OC1N(*)C(*)(*)C(N[C@@](Cc(cc1)ccc1OC1OC1N(*)*)C(O*)=O)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9828074.6 | 1998-12-18 | ||
| GBGB9828074.6A GB9828074D0 (en) | 1998-12-18 | 1998-12-18 | Therapeutically useful compounds |
| PCT/EP1999/010000 WO2000037444A1 (en) | 1998-12-18 | 1999-12-16 | Compounds useful in the treatment of inflammatory diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002533326A JP2002533326A (ja) | 2002-10-08 |
| JP2002533326A5 true JP2002533326A5 (https=) | 2006-10-19 |
| JP4431282B2 JP4431282B2 (ja) | 2010-03-10 |
Family
ID=10844608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000589516A Expired - Lifetime JP4431282B2 (ja) | 1998-12-18 | 1999-12-16 | 炎症性疾患の治療に有用な化合物 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6867192B1 (https=) |
| EP (1) | EP1140837B1 (https=) |
| JP (1) | JP4431282B2 (https=) |
| KR (1) | KR20010101258A (https=) |
| CN (1) | CN1330637A (https=) |
| AR (1) | AR023727A1 (https=) |
| AT (1) | ATE273954T1 (https=) |
| AU (1) | AU760169B2 (https=) |
| BR (1) | BR9916282A (https=) |
| CA (1) | CA2355630A1 (https=) |
| CO (1) | CO5170533A1 (https=) |
| CZ (1) | CZ20012209A3 (https=) |
| DE (1) | DE69919580T2 (https=) |
| ES (1) | ES2226488T3 (https=) |
| GB (1) | GB9828074D0 (https=) |
| GT (1) | GT199900217A (https=) |
| HK (1) | HK1038744A1 (https=) |
| HU (1) | HUP0104867A3 (https=) |
| IL (1) | IL142908A0 (https=) |
| NO (1) | NO20012995L (https=) |
| NZ (1) | NZ511478A (https=) |
| PE (1) | PE20001387A1 (https=) |
| PL (1) | PL348059A1 (https=) |
| TR (1) | TR200101709T2 (https=) |
| WO (1) | WO2000037444A1 (https=) |
| ZA (1) | ZA200103948B (https=) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU41202A (sh) | 1999-12-28 | 2005-03-15 | Pfizer Products Inc. | Ne-peptidni inhibitori vezivanja za ćeliju zavisnog od vla-4 korisni pri tretiranju inflamatornih, autoimunih i respiratornih bolesti |
| GB0014869D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Novel pharmaceutical formulation |
| GB0014881D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Pharmaceutical aerosol formulation |
| GB0014883D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Novel pharmaceutical formulation |
| GB0014892D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Novel pharmaceutical formulation |
| GB0014947D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Novel pharmaceutical formulation |
| GB0014851D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Novel pharmaceutical formulation |
| GB0014849D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Pharmaceutical aerosol formulation |
| GB0127423D0 (en) * | 2001-11-15 | 2002-01-09 | Glaxo Group Ltd | Process |
| GB0218630D0 (en) | 2002-08-10 | 2002-09-18 | Tanabe Seiyaku Co | Novel compounds |
| CA2525934A1 (en) | 2003-05-20 | 2004-12-02 | Genentech, Inc. | Thiocarbamate inhibitors of alpha-4 integrins |
| AU2005249566B2 (en) | 2004-06-04 | 2010-11-11 | Genentech, Inc. | Method for treating multiple sclerosis |
| US8482496B2 (en) | 2006-01-06 | 2013-07-09 | Pixtronix, Inc. | Circuits for controlling MEMS display apparatus on a transparent substrate |
| US20070205969A1 (en) | 2005-02-23 | 2007-09-06 | Pixtronix, Incorporated | Direct-view MEMS display devices and methods for generating images thereon |
| US9158106B2 (en) | 2005-02-23 | 2015-10-13 | Pixtronix, Inc. | Display methods and apparatus |
| US8310442B2 (en) | 2005-02-23 | 2012-11-13 | Pixtronix, Inc. | Circuits for controlling display apparatus |
| US9082353B2 (en) | 2010-01-05 | 2015-07-14 | Pixtronix, Inc. | Circuits for controlling display apparatus |
| US8519945B2 (en) | 2006-01-06 | 2013-08-27 | Pixtronix, Inc. | Circuits for controlling display apparatus |
| US9261694B2 (en) | 2005-02-23 | 2016-02-16 | Pixtronix, Inc. | Display apparatus and methods for manufacture thereof |
| US7742016B2 (en) | 2005-02-23 | 2010-06-22 | Pixtronix, Incorporated | Display methods and apparatus |
| US7999994B2 (en) | 2005-02-23 | 2011-08-16 | Pixtronix, Inc. | Display apparatus and methods for manufacture thereof |
| US9229222B2 (en) | 2005-02-23 | 2016-01-05 | Pixtronix, Inc. | Alignment methods in fluid-filled MEMS displays |
| US8159428B2 (en) | 2005-02-23 | 2012-04-17 | Pixtronix, Inc. | Display methods and apparatus |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| US8526096B2 (en) | 2006-02-23 | 2013-09-03 | Pixtronix, Inc. | Mechanical light modulators with stressed beams |
| US9176318B2 (en) * | 2007-05-18 | 2015-11-03 | Pixtronix, Inc. | Methods for manufacturing fluid-filled MEMS displays |
| AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
| US8169679B2 (en) | 2008-10-27 | 2012-05-01 | Pixtronix, Inc. | MEMS anchors |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| BR112012019383A2 (pt) | 2010-02-02 | 2017-09-12 | Pixtronix Inc | Circuitos para controlar aparelho de exibição |
| WO2011097252A2 (en) | 2010-02-02 | 2011-08-11 | Pixtronix, Inc. | Methods for manufacturing cold seal fluid-filled display apparatus |
| WO2013101771A2 (en) | 2011-12-30 | 2013-07-04 | Genentech, Inc. | Compositions and method for treating autoimmune diseases |
| KR20140119777A (ko) | 2012-01-31 | 2014-10-10 | 제넨테크, 인크. | 항-ig-e m1'' 항체 및 그의 사용 방법 |
| US9134552B2 (en) | 2013-03-13 | 2015-09-15 | Pixtronix, Inc. | Display apparatus with narrow gap electrostatic actuators |
| BR112016028081A2 (pt) * | 2014-05-30 | 2017-08-22 | Sphaera Pharma Private Ltd | Novos compostos como agentes antituberculares |
| JP6752276B2 (ja) | 2015-07-08 | 2020-09-09 | アクセロビジョン インコーポレイテッド | 眼炎症状態を処置する際に使用するための、インテグリンα４アンタゴニストを含む薬学的組成物 |
| IL293708B2 (en) | 2015-10-06 | 2026-04-01 | Genentech Inc | A method for treating multiple sclerosis |
| US11021514B2 (en) * | 2016-06-01 | 2021-06-01 | Athira Pharma, Inc. | Compounds |
| CN109722455B (zh) * | 2017-10-31 | 2022-03-11 | 中国科学院天津工业生物技术研究所 | 微生物发酵生产谷内酯的方法、工程菌及应用 |
| US20230033021A1 (en) | 2018-06-20 | 2023-02-02 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| EP3873605B1 (en) | 2018-10-30 | 2024-10-23 | Gilead Sciences, Inc. | Compounds for inhibition of alpha4beta7 integrin |
| FI3873884T3 (fi) | 2018-10-30 | 2025-02-24 | Gilead Sciences Inc | 3-(kinolin-8-yyli)-1,4-dihydropyrido[3,4-d]pyrimidiini-2,4-dionijohdannaisia alfa-4-beta-7-integriinin estäjinä tulehdussairauksien hoidossa |
| JP7189368B2 (ja) | 2018-10-30 | 2022-12-13 | ギリアード サイエンシーズ， インコーポレイテッド | アルファ４ベータ７インテグリンの阻害のための化合物 |
| ES3013256T3 (en) | 2018-10-30 | 2025-04-11 | Gilead Sciences Inc | Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| WO2021030438A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
| IL302175A (en) * | 2020-10-21 | 2023-06-01 | Azura Ophthalmics Ltd | Compounds and methods for the treatment of ocular disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1593858A1 (de) * | 1967-03-02 | 1970-10-29 | Hoechst Ag | Verfahren zur Herstellung tyrosinhaltiger Peptide und deren Derivaten |
| US4105602A (en) * | 1975-02-10 | 1978-08-08 | Armour Pharmaceutical Company | Synthesis of peptides with parathyroid hormone activity |
| US6248713B1 (en) | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
| WO1998053818A1 (en) | 1997-05-29 | 1998-12-03 | Merck & Co., Inc. | Sulfonamides as cell adhesion inhibitors |
| EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION |
| JP2001517245A (ja) * | 1997-05-29 | 2001-10-02 | メルク エンド カンパニー インコーポレーテッド | 細胞接着阻害薬としてのビアリールアルカン酸類 |
| AU7667498A (en) * | 1997-05-30 | 1998-12-30 | Celltech Therapeutics Limited | Anti-inflammatory tyrosine derivatives |
-
1998
- 1998-12-18 GB GBGB9828074.6A patent/GB9828074D0/en not_active Ceased
-
1999
- 1999-12-15 CO CO99078241A patent/CO5170533A1/es not_active Application Discontinuation
- 1999-12-15 AR ARP990106429A patent/AR023727A1/es not_active Application Discontinuation
- 1999-12-16 NZ NZ511478A patent/NZ511478A/en unknown
- 1999-12-16 HK HK02100145.2A patent/HK1038744A1/zh unknown
- 1999-12-16 CZ CZ20012209A patent/CZ20012209A3/cs unknown
- 1999-12-16 JP JP2000589516A patent/JP4431282B2/ja not_active Expired - Lifetime
- 1999-12-16 IL IL14290899A patent/IL142908A0/xx unknown
- 1999-12-16 PE PE1999001274A patent/PE20001387A1/es not_active Application Discontinuation
- 1999-12-16 CA CA002355630A patent/CA2355630A1/en not_active Abandoned
- 1999-12-16 EP EP99964583A patent/EP1140837B1/en not_active Expired - Lifetime
- 1999-12-16 TR TR2001/01709T patent/TR200101709T2/xx unknown
- 1999-12-16 ES ES99964583T patent/ES2226488T3/es not_active Expired - Lifetime
- 1999-12-16 PL PL99348059A patent/PL348059A1/xx not_active Application Discontinuation
- 1999-12-16 HU HU0104867A patent/HUP0104867A3/hu unknown
- 1999-12-16 CN CN99814654A patent/CN1330637A/zh active Pending
- 1999-12-16 AU AU30391/00A patent/AU760169B2/en not_active Ceased
- 1999-12-16 BR BR9916282-2A patent/BR9916282A/pt not_active IP Right Cessation
- 1999-12-16 KR KR1020017007579A patent/KR20010101258A/ko not_active Withdrawn
- 1999-12-16 WO PCT/EP1999/010000 patent/WO2000037444A1/en not_active Ceased
- 1999-12-16 AT AT99964583T patent/ATE273954T1/de not_active IP Right Cessation
- 1999-12-16 DE DE69919580T patent/DE69919580T2/de not_active Expired - Lifetime
- 1999-12-16 US US09/868,395 patent/US6867192B1/en not_active Expired - Lifetime
- 1999-12-17 GT GT199900217A patent/GT199900217A/es unknown
-
2001
- 2001-05-15 ZA ZA200103948A patent/ZA200103948B/en unknown
- 2001-06-15 NO NO20012995A patent/NO20012995L/no not_active Application Discontinuation
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