JP2002533096A5 - - Google Patents
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- Publication number
- JP2002533096A5 JP2002533096A5 JP2000589732A JP2000589732A JP2002533096A5 JP 2002533096 A5 JP2002533096 A5 JP 2002533096A5 JP 2000589732 A JP2000589732 A JP 2000589732A JP 2000589732 A JP2000589732 A JP 2000589732A JP 2002533096 A5 JP2002533096 A5 JP 2002533096A5
- Authority
- JP
- Japan
- Prior art keywords
- allele
- pattern
- kit
- primer
- oligonucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108700028369 Alleles Proteins 0.000 description 31
- 238000000034 method Methods 0.000 description 27
- 108091034117 Oligonucleotide Proteins 0.000 description 11
- 206010040047 Sepsis Diseases 0.000 description 9
- 238000009396 hybridization Methods 0.000 description 9
- 108010002352 Interleukin-1 Proteins 0.000 description 6
- 102000000589 Interleukin-1 Human genes 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 230000003321 amplification Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 238000003199 nucleic acid amplification method Methods 0.000 description 4
- 101710163270 Nuclease Proteins 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000012163 sequencing technique Methods 0.000 description 3
- 238000001976 enzyme digestion Methods 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 108091008146 restriction endonucleases Proteins 0.000 description 2
- 102100026018 Interleukin-1 receptor antagonist protein Human genes 0.000 description 1
- 101710144554 Interleukin-1 receptor antagonist protein Proteins 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/183,850 | 1998-10-30 | ||
| US09/183,850 US6251598B1 (en) | 1998-10-30 | 1998-10-30 | Methods for diagnosing sepsis |
| PCT/US1999/025633 WO2000037679A2 (en) | 1998-10-30 | 1999-11-01 | Method for determining the susceptibility to developing sepsis and therapeutics for the treatment of sepsis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002533096A JP2002533096A (ja) | 2002-10-08 |
| JP2002533096A5 true JP2002533096A5 (https=) | 2007-07-19 |
Family
ID=22674558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000589732A Pending JP2002533096A (ja) | 1998-10-30 | 1999-11-01 | 敗血症の診断法および治療法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6251598B1 (https=) |
| EP (1) | EP1127168B1 (https=) |
| JP (1) | JP2002533096A (https=) |
| AT (1) | ATE403745T1 (https=) |
| AU (1) | AU779772B2 (https=) |
| CA (1) | CA2346960A1 (https=) |
| DE (1) | DE69939269D1 (https=) |
| ES (1) | ES2308861T3 (https=) |
| IL (1) | IL142438A0 (https=) |
| WO (1) | WO2000037679A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| US20050032077A1 (en) * | 1998-03-10 | 2005-02-10 | Duff Gordon W. | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
| WO2002024951A1 (en) * | 2000-09-20 | 2002-03-28 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the il1b gene |
| US20040028651A1 (en) * | 2001-03-29 | 2004-02-12 | Karrupiah Muthumani | Composition and methods of using hiv vpr |
| JP2005523879A (ja) * | 2001-10-05 | 2005-08-11 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | Ｓｉｒｓ／ｓｅｐｓｉｓを治療及び予防するための組成物及び方法 |
| WO2003044176A2 (en) * | 2001-11-19 | 2003-05-30 | Interleukin Genetics, Inc. | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
| US20080311581A1 (en) * | 2001-11-19 | 2008-12-18 | David Wyllie | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
| BR0316232A (pt) * | 2002-11-12 | 2005-10-04 | Becton Dickinson Co | Métodos para determinar o estado de sepsia, para prognosticar o começo de sepsia e para diagnosticar a sìndrome de resposta inflamatória sistêmica em um indivìduo |
| CA2505843A1 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| MXPA05005073A (es) * | 2002-11-12 | 2005-11-17 | Becton Dickinson Co | Diagnostico de la sepsis o sirs usando perfiles de biomarcadores. |
| WO2005038427A2 (en) * | 2003-06-05 | 2005-04-28 | Medical Gene Center Ltd. | Rapid identification of viruses of the upper respiratory tract infection including sars causing coronus viruses |
| PT1673472E (pt) * | 2003-10-06 | 2011-05-12 | Novartis Ag | Utiliza??o de polimorfismos gen?ticos na predi??o de hepatotoxicidade induzida por f?rmacos |
| US20090176206A1 (en) * | 2004-03-04 | 2009-07-09 | James Russell | Toll-like receptor 2 (tlr-2) haplotypes predict outcome of patients |
| AU2005219472A1 (en) * | 2004-03-04 | 2005-09-15 | The University Of British Columbia | Thrombomodulin (THBD) haplotypes predict outcome of patients |
| US8034553B2 (en) * | 2004-06-24 | 2011-10-11 | Kimberly-Clark Worldwide, Inc. | Biomarkers for wound healing |
| US20060157647A1 (en) * | 2005-01-18 | 2006-07-20 | Becton, Dickinson And Company | Multidimensional liquid chromatography/spectrometry |
| EP2361933A3 (en) | 2005-01-26 | 2012-05-02 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| RU2286154C2 (ru) * | 2005-02-17 | 2006-10-27 | Владимир Алексеевич Шатров | Способ лечения воспалительных заболеваний головного мозга |
| WO2006106868A1 (ja) | 2005-03-30 | 2006-10-12 | Shimadzu Corporation | 反応容器における不揮発性液体分注方法及び反応容器処理装置 |
| JP2008538007A (ja) | 2005-04-15 | 2008-10-02 | ベクトン，ディッキンソン アンド カンパニー | 敗血症の診断 |
| US8669113B2 (en) | 2008-04-03 | 2014-03-11 | Becton, Dickinson And Company | Advanced detection of sepsis |
| WO2010070136A2 (en) * | 2008-12-19 | 2010-06-24 | Centre de Recherche Public de la Santé | Novel caviidae allergens and uses thereof |
| KR101451357B1 (ko) | 2011-02-18 | 2014-10-15 | 주식회사 스템디알 | Ｓｉｒｔ１ 발현 유도 물질을 포함하는 패혈증 또는 패혈증 쇼크의 예방 또는 치료용 조성물 |
| US10126305B2 (en) | 2013-06-25 | 2018-11-13 | University of Pittsburg—Of the Commonwealth System of Higher Education | Proteomic biomarkers of sepsis in elderly patients |
| WO2017123696A1 (en) | 2016-01-12 | 2017-07-20 | Interleukin Genetics, Inc. | Methods for predicting response to treatment |
| US10337070B2 (en) | 2017-01-12 | 2019-07-02 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| US20220249660A1 (en) | 2019-06-06 | 2022-08-11 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| AU655766B2 (en) | 1990-05-01 | 1995-01-12 | Chiron Corporation | Interleukin-1 antagonist and uses thereof |
| US5916891A (en) | 1992-01-13 | 1999-06-29 | Smithkline Beecham Corporation | Pyrimidinyl imidazoles |
| WO1995001997A1 (en) | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| DE4408890A1 (de) | 1994-03-16 | 1995-09-21 | Knoll Ag | Verwendung von Il-1-Antagonisten als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel |
| US5686246A (en) * | 1995-08-03 | 1997-11-11 | Kornman; Kenneth S. | Detecting genetic predisposition to periodontal disease |
| US5942390A (en) * | 1996-01-12 | 1999-08-24 | Cedars-Sinai Medical Center | Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism |
| AU2213697A (en) | 1996-03-18 | 1997-10-10 | Medical Science Systems, Inc. | A method for periodontal disease treatment |
| GB9621129D0 (en) | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6210877B1 (en) | 1997-03-10 | 2001-04-03 | Interleukin Genetics, Inc. | Prediction of coronary artery disease |
| GB9711040D0 (en) | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| ES2297900T3 (es) | 1997-11-07 | 2008-05-01 | Interleukin Genetics, Inc. | Diagnosis y terapia para la enfermedad obstructiva cronica de las vias respiratorias. |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
-
1998
- 1998-10-30 US US09/183,850 patent/US6251598B1/en not_active Expired - Fee Related
-
1999
- 1999-11-01 WO PCT/US1999/025633 patent/WO2000037679A2/en not_active Ceased
- 1999-11-01 AT AT99972008T patent/ATE403745T1/de not_active IP Right Cessation
- 1999-11-01 EP EP99972008A patent/EP1127168B1/en not_active Expired - Lifetime
- 1999-11-01 ES ES99972008T patent/ES2308861T3/es not_active Expired - Lifetime
- 1999-11-01 DE DE69939269T patent/DE69939269D1/de not_active Expired - Lifetime
- 1999-11-01 AU AU39956/00A patent/AU779772B2/en not_active Ceased
- 1999-11-01 IL IL14243899A patent/IL142438A0/xx unknown
- 1999-11-01 JP JP2000589732A patent/JP2002533096A/ja active Pending
- 1999-11-01 CA CA002346960A patent/CA2346960A1/en not_active Abandoned
-
2001
- 2001-05-10 US US09/852,948 patent/US6551785B2/en not_active Expired - Fee Related
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