JP2002533096A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002533096A5 JP2002533096A5 JP2000589732A JP2000589732A JP2002533096A5 JP 2002533096 A5 JP2002533096 A5 JP 2002533096A5 JP 2000589732 A JP2000589732 A JP 2000589732A JP 2000589732 A JP2000589732 A JP 2000589732A JP 2002533096 A5 JP2002533096 A5 JP 2002533096A5
- Authority
- JP
- Japan
- Prior art keywords
- allele
- pattern
- kit
- primer
- oligonucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108700028369 Alleles Proteins 0.000 description 31
- 238000000034 method Methods 0.000 description 27
- 108091034117 Oligonucleotide Proteins 0.000 description 11
- 206010040047 Sepsis Diseases 0.000 description 9
- 238000009396 hybridization Methods 0.000 description 9
- 108010002352 Interleukin-1 Proteins 0.000 description 6
- 102000000589 Interleukin-1 Human genes 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 230000003321 amplification Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 238000003199 nucleic acid amplification method Methods 0.000 description 4
- 101710163270 Nuclease Proteins 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000012163 sequencing technique Methods 0.000 description 3
- 238000001976 enzyme digestion Methods 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 108091008146 restriction endonucleases Proteins 0.000 description 2
- 102100026018 Interleukin-1 receptor antagonist protein Human genes 0.000 description 1
- 101710144554 Interleukin-1 receptor antagonist protein Proteins 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/183,850 | 1998-10-30 | ||
| US09/183,850 US6251598B1 (en) | 1998-10-30 | 1998-10-30 | Methods for diagnosing sepsis |
| PCT/US1999/025633 WO2000037679A2 (en) | 1998-10-30 | 1999-11-01 | Method for determining the susceptibility to developing sepsis and therapeutics for the treatment of sepsis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002533096A JP2002533096A (ja) | 2002-10-08 |
| JP2002533096A5 true JP2002533096A5 (https=) | 2007-07-19 |
Family
ID=22674558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000589732A Pending JP2002533096A (ja) | 1998-10-30 | 1999-11-01 | 敗血症の診断法および治療法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6251598B1 (https=) |
| EP (1) | EP1127168B1 (https=) |
| JP (1) | JP2002533096A (https=) |
| AT (1) | ATE403745T1 (https=) |
| AU (1) | AU779772B2 (https=) |
| CA (1) | CA2346960A1 (https=) |
| DE (1) | DE69939269D1 (https=) |
| ES (1) | ES2308861T3 (https=) |
| IL (1) | IL142438A0 (https=) |
| WO (1) | WO2000037679A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| US20050032077A1 (en) * | 1998-03-10 | 2005-02-10 | Duff Gordon W. | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
| AU2001263373A1 (en) * | 2000-09-20 | 2002-04-02 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the il1b gene |
| US20040028651A1 (en) * | 2001-03-29 | 2004-02-12 | Karrupiah Muthumani | Composition and methods of using hiv vpr |
| WO2003030827A2 (en) * | 2001-10-05 | 2003-04-17 | The Trustees Of The University Of Pennsylvania | Compositions for and methods of treating and preventing sirs/sepsis |
| CN1753903B (zh) * | 2001-11-19 | 2010-05-12 | 白介素遗传公司 | 影响转录和对炎性和传染性疾病的敏感性的白细胞介素-1基因座的功能多态性 |
| US20080311581A1 (en) * | 2001-11-19 | 2008-12-18 | David Wyllie | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
| WO2004044556A2 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| US20040096917A1 (en) * | 2002-11-12 | 2004-05-20 | Becton, Dickinson And Company | Diagnosis of sepsis or SIRS using biomarker profiles |
| WO2004044555A2 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| WO2005038427A2 (en) * | 2003-06-05 | 2005-04-28 | Medical Gene Center Ltd. | Rapid identification of viruses of the upper respiratory tract infection including sars causing coronus viruses |
| ES2361018T3 (es) * | 2003-10-06 | 2011-06-13 | Novartis Ag | Uso de polimorfismos genéticos para predecir la hepatotoxicidad inducida por fármacos. |
| WO2005085273A1 (en) * | 2004-03-04 | 2005-09-15 | The University Of British Columbia | Thrombomodulin (thbd) haplotypes predict outcome of patients |
| EP1723160A4 (en) * | 2004-03-04 | 2008-04-23 | Univ British Columbia | FORECAST OF PATIENT STATUS EVOLUTION USING TOLL-RECEPTOR 2 (TLR-2) HAPLOTYPES |
| US8034553B2 (en) * | 2004-06-24 | 2011-10-11 | Kimberly-Clark Worldwide, Inc. | Biomarkers for wound healing |
| US20060157647A1 (en) * | 2005-01-18 | 2006-07-20 | Becton, Dickinson And Company | Multidimensional liquid chromatography/spectrometry |
| EP1851245B1 (en) | 2005-01-26 | 2012-10-10 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| RU2286154C2 (ru) * | 2005-02-17 | 2006-10-27 | Владимир Алексеевич Шатров | Способ лечения воспалительных заболеваний головного мозга |
| US8293521B2 (en) | 2005-03-30 | 2012-10-23 | Shimadzu Corporation | Method of dispensing nonvolatile liquid in reaction vessel and reaction vessel processing apparatus |
| CA2605143A1 (en) | 2005-04-15 | 2006-10-26 | Becton, Dickinson And Company | Diagnosis of sepsis |
| US8669113B2 (en) | 2008-04-03 | 2014-03-11 | Becton, Dickinson And Company | Advanced detection of sepsis |
| WO2010070136A2 (en) * | 2008-12-19 | 2010-06-24 | Centre de Recherche Public de la Santé | Novel caviidae allergens and uses thereof |
| US9913880B2 (en) | 2011-02-18 | 2018-03-13 | Stemdr Inc. | Method of treating sepsis or septic shock |
| WO2014210031A1 (en) | 2013-06-25 | 2014-12-31 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Proteomic biomarkers of sepsis in elderly patients |
| CA3011363A1 (en) | 2016-01-12 | 2017-07-20 | Interleukin Genetics, Inc. | Methods for predicting response to treatment |
| US10329620B2 (en) | 2017-01-12 | 2019-06-25 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| US20220249660A1 (en) | 2019-06-06 | 2022-08-11 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| CA2081774A1 (en) | 1990-05-01 | 1991-11-02 | John Stephen Haskill | Interleukin-1 antagonist and uses thereof |
| US5916891A (en) | 1992-01-13 | 1999-06-29 | Smithkline Beecham Corporation | Pyrimidinyl imidazoles |
| WO1995001997A1 (en) | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| DE4408890A1 (de) | 1994-03-16 | 1995-09-21 | Knoll Ag | Verwendung von Il-1-Antagonisten als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel |
| US5686246A (en) | 1995-08-03 | 1997-11-11 | Kornman; Kenneth S. | Detecting genetic predisposition to periodontal disease |
| US5942390A (en) * | 1996-01-12 | 1999-08-24 | Cedars-Sinai Medical Center | Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism |
| AU2213697A (en) | 1996-03-18 | 1997-10-10 | Medical Science Systems, Inc. | A method for periodontal disease treatment |
| GB9621129D0 (en) | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6210877B1 (en) | 1997-03-10 | 2001-04-03 | Interleukin Genetics, Inc. | Prediction of coronary artery disease |
| GB9711040D0 (en) | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| IL135957A0 (en) | 1997-11-07 | 2001-05-20 | Interleukin Genetics Inc | Diagnostics and therapeutics for chronic obstructive airway disease |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
-
1998
- 1998-10-30 US US09/183,850 patent/US6251598B1/en not_active Expired - Fee Related
-
1999
- 1999-11-01 WO PCT/US1999/025633 patent/WO2000037679A2/en not_active Ceased
- 1999-11-01 AU AU39956/00A patent/AU779772B2/en not_active Ceased
- 1999-11-01 EP EP99972008A patent/EP1127168B1/en not_active Expired - Lifetime
- 1999-11-01 ES ES99972008T patent/ES2308861T3/es not_active Expired - Lifetime
- 1999-11-01 IL IL14243899A patent/IL142438A0/xx unknown
- 1999-11-01 AT AT99972008T patent/ATE403745T1/de not_active IP Right Cessation
- 1999-11-01 CA CA002346960A patent/CA2346960A1/en not_active Abandoned
- 1999-11-01 JP JP2000589732A patent/JP2002533096A/ja active Pending
- 1999-11-01 DE DE69939269T patent/DE69939269D1/de not_active Expired - Lifetime
-
2001
- 2001-05-10 US US09/852,948 patent/US6551785B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002533096A5 (https=) | ||
| JP2003500071A5 (https=) | ||
| US7169358B2 (en) | Electrochemical detection of nucleic acid sequences | |
| JP3937136B2 (ja) | 塩基多型の検出方法 | |
| CA2369045A1 (en) | Methods for improving sensitivity and specificity of screening assays | |
| CA2374916A1 (en) | Diagnostics and therapeutics for cardiovascular disorders | |
| Syvänen et al. | Direct sequencing of affinity‐captured amplified human DNA application to the detection of apolipoprotein E polymorphism | |
| JP2002539848A5 (https=) | ||
| WO1990013668A1 (en) | Method for genetic analysis of a nucleic acid sample | |
| EP1375672A1 (en) | Method of detecting nucleic acid relating to disease | |
| Litos et al. | Genotyping of single-nucleotide polymorphisms by primer extension reaction in a dry-reagent dipstick format | |
| CN102796828A (zh) | 用于检测乙型肝炎病毒的抗药性株系的核酸引物组、测定试剂盒及检测乙型肝炎病毒的抗药性株系的方法 | |
| JP2004504802A5 (https=) | ||
| CA2462932A1 (en) | Method for the detection of cytosine methylations in immobilized dna samples | |
| JP4410269B2 (ja) | Ｎ−アセチルトランスフェラーゼ２（ｎａｔ２）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法 | |
| JP2004500020A (ja) | 半導体マイクロチップ上の電子的ドットブロットアッセイによる一塩基多型の識別 | |
| JP2007501627A5 (https=) | ||
| EP1612282B1 (en) | Probe set and substrate for detecting nucleic acid | |
| AU4766000A (en) | Method for analysing a patient's genetic predisposition to at least a disease and amplification adapted to such a method | |
| JP2003500067A5 (https=) | ||
| Bang‐Ce et al. | Rapid detection of common Chinese glucose‐6‐phosphate dehydrogenase (G6PD) mutations by microarray‐based assay | |
| US20070003938A1 (en) | Hybridization of genomic nucleic acid without complexity reduction | |
| Nakamura et al. | Simple and accurate determination of CYP2D6 gene copy number by a loop-mediated isothermal amplification method and an electrochemical DNA chip | |
| Carvalho et al. | Optimization of a multiplex minisequencing protocol for population studies and medical genetics | |
| JP2008079604A (ja) | アルコール分解能と宿酔の耐性とを予測するためのプライマーセット、プローブセット、方法及びキット |