IL142438A0 - Diagnostic and therapeutics for sepsis - Google Patents
Diagnostic and therapeutics for sepsisInfo
- Publication number
- IL142438A0 IL142438A0 IL14243899A IL14243899A IL142438A0 IL 142438 A0 IL142438 A0 IL 142438A0 IL 14243899 A IL14243899 A IL 14243899A IL 14243899 A IL14243899 A IL 14243899A IL 142438 A0 IL142438 A0 IL 142438A0
- Authority
- IL
- Israel
- Prior art keywords
- sepsis
- therapeutics
- diagnostic
- susceptibility
- predictive
- Prior art date
Links
- 206010040047 Sepsis Diseases 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/131—Allele specific probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/183,850 US6251598B1 (en) | 1998-10-30 | 1998-10-30 | Methods for diagnosing sepsis |
| PCT/US1999/025633 WO2000037679A2 (en) | 1998-10-30 | 1999-11-01 | Method for determining the susceptibility to developing sepsis and therapeutics for the treatment of sepsis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL142438A0 true IL142438A0 (en) | 2002-03-10 |
Family
ID=22674558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14243899A IL142438A0 (en) | 1998-10-30 | 1999-11-01 | Diagnostic and therapeutics for sepsis |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6251598B1 (https=) |
| EP (1) | EP1127168B1 (https=) |
| JP (1) | JP2002533096A (https=) |
| AT (1) | ATE403745T1 (https=) |
| AU (1) | AU779772B2 (https=) |
| CA (1) | CA2346960A1 (https=) |
| DE (1) | DE69939269D1 (https=) |
| ES (1) | ES2308861T3 (https=) |
| IL (1) | IL142438A0 (https=) |
| WO (1) | WO2000037679A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| US20050032077A1 (en) * | 1998-03-10 | 2005-02-10 | Duff Gordon W. | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
| AU2001263373A1 (en) * | 2000-09-20 | 2002-04-02 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the il1b gene |
| US20040028651A1 (en) * | 2001-03-29 | 2004-02-12 | Karrupiah Muthumani | Composition and methods of using hiv vpr |
| WO2003030827A2 (en) * | 2001-10-05 | 2003-04-17 | The Trustees Of The University Of Pennsylvania | Compositions for and methods of treating and preventing sirs/sepsis |
| CN1753903B (zh) * | 2001-11-19 | 2010-05-12 | 白介素遗传公司 | 影响转录和对炎性和传染性疾病的敏感性的白细胞介素-1基因座的功能多态性 |
| US20080311581A1 (en) * | 2001-11-19 | 2008-12-18 | David Wyllie | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
| WO2004044556A2 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| US20040096917A1 (en) * | 2002-11-12 | 2004-05-20 | Becton, Dickinson And Company | Diagnosis of sepsis or SIRS using biomarker profiles |
| WO2004044555A2 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| WO2005038427A2 (en) * | 2003-06-05 | 2005-04-28 | Medical Gene Center Ltd. | Rapid identification of viruses of the upper respiratory tract infection including sars causing coronus viruses |
| ES2361018T3 (es) * | 2003-10-06 | 2011-06-13 | Novartis Ag | Uso de polimorfismos genéticos para predecir la hepatotoxicidad inducida por fármacos. |
| WO2005085273A1 (en) * | 2004-03-04 | 2005-09-15 | The University Of British Columbia | Thrombomodulin (thbd) haplotypes predict outcome of patients |
| EP1723160A4 (en) * | 2004-03-04 | 2008-04-23 | Univ British Columbia | FORECAST OF PATIENT STATUS EVOLUTION USING TOLL-RECEPTOR 2 (TLR-2) HAPLOTYPES |
| US8034553B2 (en) * | 2004-06-24 | 2011-10-11 | Kimberly-Clark Worldwide, Inc. | Biomarkers for wound healing |
| US20060157647A1 (en) * | 2005-01-18 | 2006-07-20 | Becton, Dickinson And Company | Multidimensional liquid chromatography/spectrometry |
| EP1851245B1 (en) | 2005-01-26 | 2012-10-10 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| RU2286154C2 (ru) * | 2005-02-17 | 2006-10-27 | Владимир Алексеевич Шатров | Способ лечения воспалительных заболеваний головного мозга |
| US8293521B2 (en) | 2005-03-30 | 2012-10-23 | Shimadzu Corporation | Method of dispensing nonvolatile liquid in reaction vessel and reaction vessel processing apparatus |
| CA2605143A1 (en) | 2005-04-15 | 2006-10-26 | Becton, Dickinson And Company | Diagnosis of sepsis |
| US8669113B2 (en) | 2008-04-03 | 2014-03-11 | Becton, Dickinson And Company | Advanced detection of sepsis |
| WO2010070136A2 (en) * | 2008-12-19 | 2010-06-24 | Centre de Recherche Public de la Santé | Novel caviidae allergens and uses thereof |
| US9913880B2 (en) | 2011-02-18 | 2018-03-13 | Stemdr Inc. | Method of treating sepsis or septic shock |
| WO2014210031A1 (en) | 2013-06-25 | 2014-12-31 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Proteomic biomarkers of sepsis in elderly patients |
| CA3011363A1 (en) | 2016-01-12 | 2017-07-20 | Interleukin Genetics, Inc. | Methods for predicting response to treatment |
| US10329620B2 (en) | 2017-01-12 | 2019-06-25 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| US20220249660A1 (en) | 2019-06-06 | 2022-08-11 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| CA2081774A1 (en) | 1990-05-01 | 1991-11-02 | John Stephen Haskill | Interleukin-1 antagonist and uses thereof |
| US5916891A (en) | 1992-01-13 | 1999-06-29 | Smithkline Beecham Corporation | Pyrimidinyl imidazoles |
| WO1995001997A1 (en) | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| DE4408890A1 (de) | 1994-03-16 | 1995-09-21 | Knoll Ag | Verwendung von Il-1-Antagonisten als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel |
| US5686246A (en) | 1995-08-03 | 1997-11-11 | Kornman; Kenneth S. | Detecting genetic predisposition to periodontal disease |
| US5942390A (en) * | 1996-01-12 | 1999-08-24 | Cedars-Sinai Medical Center | Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism |
| AU2213697A (en) | 1996-03-18 | 1997-10-10 | Medical Science Systems, Inc. | A method for periodontal disease treatment |
| GB9621129D0 (en) | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6210877B1 (en) | 1997-03-10 | 2001-04-03 | Interleukin Genetics, Inc. | Prediction of coronary artery disease |
| GB9711040D0 (en) | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| IL135957A0 (en) | 1997-11-07 | 2001-05-20 | Interleukin Genetics Inc | Diagnostics and therapeutics for chronic obstructive airway disease |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
-
1998
- 1998-10-30 US US09/183,850 patent/US6251598B1/en not_active Expired - Fee Related
-
1999
- 1999-11-01 WO PCT/US1999/025633 patent/WO2000037679A2/en not_active Ceased
- 1999-11-01 AU AU39956/00A patent/AU779772B2/en not_active Ceased
- 1999-11-01 EP EP99972008A patent/EP1127168B1/en not_active Expired - Lifetime
- 1999-11-01 ES ES99972008T patent/ES2308861T3/es not_active Expired - Lifetime
- 1999-11-01 IL IL14243899A patent/IL142438A0/xx unknown
- 1999-11-01 AT AT99972008T patent/ATE403745T1/de not_active IP Right Cessation
- 1999-11-01 CA CA002346960A patent/CA2346960A1/en not_active Abandoned
- 1999-11-01 JP JP2000589732A patent/JP2002533096A/ja active Pending
- 1999-11-01 DE DE69939269T patent/DE69939269D1/de not_active Expired - Lifetime
-
2001
- 2001-05-10 US US09/852,948 patent/US6551785B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000037679A2 (en) | 2000-06-29 |
| CA2346960A1 (en) | 2000-06-29 |
| ES2308861T3 (es) | 2008-12-01 |
| AU3995600A (en) | 2000-07-12 |
| US6251598B1 (en) | 2001-06-26 |
| US6551785B2 (en) | 2003-04-22 |
| US20010034032A1 (en) | 2001-10-25 |
| EP1127168A2 (en) | 2001-08-29 |
| EP1127168B1 (en) | 2008-08-06 |
| AU779772B2 (en) | 2005-02-10 |
| WO2000037679A3 (en) | 2001-01-11 |
| ATE403745T1 (de) | 2008-08-15 |
| JP2002533096A (ja) | 2002-10-08 |
| DE69939269D1 (de) | 2008-09-18 |
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