JP2002531055A - 肺炎連鎖球菌のタンパク質及び核酸分子 - Google Patents

肺炎連鎖球菌のタンパク質及び核酸分子

Info

Publication number
JP2002531055A
JP2002531055A JP2000562519A JP2000562519A JP2002531055A JP 2002531055 A JP2002531055 A JP 2002531055A JP 2000562519 A JP2000562519 A JP 2000562519A JP 2000562519 A JP2000562519 A JP 2000562519A JP 2002531055 A JP2002531055 A JP 2002531055A
Authority
JP
Japan
Prior art keywords
sequence
protein
polypeptide
pneumoniae
outside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000562519A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002531055A5 (https=
Inventor
フランシス ガイ ギルバート，クリストフ
マイケル ハンスブロ，フィリップ
Original Assignee
マイクロビアル テクニクス リミティッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9816337.1A external-priority patent/GB9816337D0/en
Application filed by マイクロビアル テクニクス リミティッド filed Critical マイクロビアル テクニクス リミティッド
Publication of JP2002531055A publication Critical patent/JP2002531055A/ja
Publication of JP2002531055A5 publication Critical patent/JP2002531055A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2000562519A 1998-07-27 1999-07-27 肺炎連鎖球菌のタンパク質及び核酸分子 Pending JP2002531055A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9816337.1A GB9816337D0 (en) 1998-07-27 1998-07-27 Proteins
US12516499P 1999-03-19 1999-03-19
US60/125,164 1999-03-19
US9816337.1 1999-03-19
PCT/GB1999/002451 WO2000006737A2 (en) 1998-07-27 1999-07-27 Streptococcus pneumoniae proteins and nucleic acid molecules

Related Child Applications (5)

Application Number Title Priority Date Filing Date
JP2008080923A Division JP2008263968A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008081183A Division JP2008263969A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008081417A Division JP2008263970A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008080545A Division JP2008263966A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2009035978A Division JP2009148283A (ja) 1998-07-27 2009-02-19 肺炎連鎖球菌のタンパク質及び核酸分子

Publications (2)

Publication Number Publication Date
JP2002531055A true JP2002531055A (ja) 2002-09-24
JP2002531055A5 JP2002531055A5 (https=) 2010-02-25

Family

ID=26314125

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2000562519A Pending JP2002531055A (ja) 1998-07-27 1999-07-27 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008081183A Pending JP2008263969A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008080923A Pending JP2008263968A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008080545A Pending JP2008263966A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008081417A Pending JP2008263970A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2009035978A Pending JP2009148283A (ja) 1998-07-27 2009-02-19 肺炎連鎖球菌のタンパク質及び核酸分子

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2008081183A Pending JP2008263969A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008080923A Pending JP2008263968A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008080545A Pending JP2008263966A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2008081417A Pending JP2008263970A (ja) 1998-07-27 2008-03-26 肺炎連鎖球菌のタンパク質及び核酸分子
JP2009035978A Pending JP2009148283A (ja) 1998-07-27 2009-02-19 肺炎連鎖球菌のタンパク質及び核酸分子

Country Status (5)

Country Link
EP (2) EP1100921B1 (https=)
JP (6) JP2002531055A (https=)
AT (1) ATE361365T1 (https=)
DE (1) DE69935986D1 (https=)
WO (1) WO2000006737A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010057501A (ja) * 2002-11-07 2010-03-18 Synergy America Inc 肺炎球菌感染を治療または予防するための組成物および方法
JP2018521640A (ja) * 2015-06-05 2018-08-09 オックスフォード ユニバーシティ イノベーション リミテッドＯｘｆｏｒｄ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 融合タンパク質を合成するための方法および製品

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
ES2322306T3 (es) * 1998-12-21 2009-06-18 Medimmune, Inc. Proteinas de streptpcpccus pneumoniae y fragmentos inmunogenicos para vacunas.
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
EP1950302B1 (en) 1998-12-23 2012-12-05 ID Biomedical Corporation of Quebec Streptococcus antigens
ES2400280T3 (es) * 1998-12-23 2013-04-08 Id Biomedical Corporation Of Quebec Antígenos de estreptococos
EP1075841A1 (en) * 1999-08-13 2001-02-14 Erasmus Universiteit Rotterdam Pneumococcal vaccines
AU2001270381B2 (en) * 2000-06-20 2007-05-24 Id Biomedical Corporation Streptococcus antigens
US7074415B2 (en) 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
US7892552B2 (en) 2001-08-08 2011-02-22 University Of Utah Research Foundation Group B Streptococcus polypeptides nucleic acids and therapeutic compositions and vaccines thereof
PT1320542E (pt) 2000-08-08 2007-08-06 St Jude Childrens Res Hospital Ácidos nucleicos de estreptococo de grupo b, polipéptidos, composições terapêuticas e vacinas correspondentes
DK1328543T3 (da) 2000-10-27 2009-11-23 Novartis Vaccines & Diagnostic Nukleinsyrer og proteiner fra streptococcus-gruppe A & B
EP1343895B1 (en) 2000-12-21 2008-06-18 ID Biomedical Corporation Streptococcus pyogenes antigens and corresponding dna fragments
GB0107658D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
EP1456231A2 (en) 2001-12-20 2004-09-15 Shire Biochem Inc. Streptococcus antigens
EP2333114A1 (en) * 2003-04-15 2011-06-15 Intercell AG S. pneumoniae antigens
JP4875490B2 (ja) 2003-07-31 2012-02-15 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド ＳｔｒｅｐｔｏｃｏｃｃｕｓＰｙｏｇｅｎｅｓについての免疫原組成物
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
CA2545325C (en) * 2003-11-10 2015-01-13 Uab Research Foundation Compositions for reducing bacterial carriage and cns invasion and methods of using same
AU2007285775B2 (en) 2006-08-17 2011-03-03 Sanofi Pasteur Ltd. Immunogenic PcpA polypeptides and uses thereof
US8722055B2 (en) * 2006-09-27 2014-05-13 St. Jude Children's Research Hospital Synthetic Streptococcus pneumoniae vaccine
EP2450054B1 (en) * 2007-04-12 2018-07-18 Stichting Katholieke Universiteit New virulence factors of Streptococcus pneumoniae
US8329195B2 (en) 2007-05-23 2012-12-11 The Uab Research Foundation Detoxified pneumococcal neuraminidase and uses thereof
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
CA2699513C (en) 2007-09-12 2018-03-13 Novartis Ag Gas57 mutant antigens and gas57 antibodies
PT2268618E (pt) 2008-03-03 2015-10-12 Novartis Ag Compostos e composições moduladores da actividade tlr
CA2765112A1 (en) 2009-06-10 2010-12-16 Novartis Ag Benzonaphthyridine-containing vaccines
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
ES2443952T3 (es) 2009-09-02 2014-02-21 Novartis Ag Composiciones inmunógenas que incluyen moduladores de la actividad de TLR
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
SG10201501980SA (en) 2009-12-15 2015-05-28 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
WO2011105891A1 (en) 2010-02-23 2011-09-01 Stichting Katholieke Universiteit, More Particularly The Radboud University Nijmegen Medical Centre Combination vaccine for streptococcus
EP2550289A4 (en) 2010-03-12 2013-11-27 Childrens Medical Center NEW IMMUNOGENES AND METHODS FOR IDENTIFICATION AND SCREENING THEREOF
AU2011232421B2 (en) 2010-03-23 2015-08-13 Novartis Ag Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc.
JP2015510872A (ja) 2012-03-07 2015-04-13 ノバルティス アーゲー Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ抗原の増強された製剤
JP6411378B2 (ja) 2013-02-01 2018-10-24 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Ｔｏｌｌ様受容体アゴニストを含む免疫学的組成物の皮内送達
JP6494527B2 (ja) 2013-02-07 2019-04-03 ザ チルドレンズ メディカル センター コーポレーション 肺炎球菌のコロニー形成および／または疾患からの保護を提供するタンパク質抗原
ES2985591T3 (es) 2018-02-12 2024-11-06 Inimmune Corp Ligandos de receptores tipo Toll
IL281204B2 (en) 2018-09-12 2025-07-01 Affinivax Inc Multivalent pneumococcal vaccines
KR20230098825A (ko) 2020-11-04 2023-07-04 엘리고 바이오사이언스 씨. 아크네스 개체군에게 dna 페이로드의 원위치 전달을 위한 파지-유래 입자
IL326005A (en) 2021-09-09 2026-03-01 Affinivax Inc Multivalent pneumococcal vaccines

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0866198A (ja) * 1994-05-20 1996-03-12 Uab Res Found 肺炎球菌の表面タンパクａのエピトープ領域

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2116261A1 (en) * 1993-04-20 1994-10-21 David E. Briles Epitopic regions of pneumococcal surface protein a
US5928900A (en) * 1993-09-01 1999-07-27 The Rockefeller University Bacterial exported proteins and acellular vaccines based thereon
EP0956289A4 (en) * 1996-08-16 2004-10-13 Smithkline Beecham Corp NOVEL PROKARYOTA POLYNUCLEOTIDES AND POLYPEPTIDES AND USES THEREOF
JP4469026B2 (ja) * 1996-10-31 2010-05-26 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅの抗原およびワクチン
EP0885966A3 (en) * 1997-06-20 1999-12-29 Smithkline Beecham Corporation Novel compouds
EP0891984A3 (en) * 1997-06-20 2000-01-19 Smithkline Beecham Corporation Nucleic acid encoding streptococcus pneumoniae response regulator
EP1783224A3 (en) * 1998-07-27 2007-08-15 Sanofi Pasteur Limited Streptococcus pneumoniae proteins and nucleic acid molecules

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0866198A (ja) * 1994-05-20 1996-03-12 Uab Res Found 肺炎球菌の表面タンパクａのエピトープ領域

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010057501A (ja) * 2002-11-07 2010-03-18 Synergy America Inc 肺炎球菌感染を治療または予防するための組成物および方法
JP2018521640A (ja) * 2015-06-05 2018-08-09 オックスフォード ユニバーシティ イノベーション リミテッドＯｘｆｏｒｄ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 融合タンパク質を合成するための方法および製品

Also Published As

Publication number Publication date
EP1100921B1 (en) 2007-05-02
ATE361365T1 (de) 2007-05-15
JP2008263968A (ja) 2008-11-06
WO2000006737A2 (en) 2000-02-10
JP2008263970A (ja) 2008-11-06
EP2053126A1 (en) 2009-04-29
JP2009148283A (ja) 2009-07-09
JP2008263966A (ja) 2008-11-06
WO2000006737A3 (en) 2000-06-29
JP2008263969A (ja) 2008-11-06
DE69935986D1 (de) 2007-06-14
WO2000006737A8 (en) 2000-11-09
EP1100921A2 (en) 2001-05-23

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