JP2002530341A5 - - Google Patents
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- Publication number
- JP2002530341A5 JP2002530341A5 JP2000583533A JP2000583533A JP2002530341A5 JP 2002530341 A5 JP2002530341 A5 JP 2002530341A5 JP 2000583533 A JP2000583533 A JP 2000583533A JP 2000583533 A JP2000583533 A JP 2000583533A JP 2002530341 A5 JP2002530341 A5 JP 2002530341A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- pharmaceutically acceptable
- acceptable salt
- jig
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 22
- FHPIXVHJEIZKJW-UHFFFAOYSA-N 4'-N-desmethylolanzapine Chemical compound S1C(C)=CC2=C1NC1=CC=CC=C1N=C2N1CCNCC1 FHPIXVHJEIZKJW-UHFFFAOYSA-N 0.000 description 15
- 150000003839 salts Chemical class 0.000 description 15
- 239000004480 active ingredient Substances 0.000 description 12
- 208000019901 Anxiety disease Diseases 0.000 description 6
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 description 3
- RTHCYVBBDHJXIQ-MRXNPFEDSA-N (R)-fluoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-MRXNPFEDSA-N 0.000 description 3
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 229960002464 fluoxetine Drugs 0.000 description 3
- 229960004038 fluvoxamine Drugs 0.000 description 3
- CJOFXWAVKWHTFT-XSFVSMFZSA-N fluvoxamine Chemical compound COCCCC\C(=N/OCCN)C1=CC=C(C(F)(F)F)C=C1 CJOFXWAVKWHTFT-XSFVSMFZSA-N 0.000 description 3
- 229960001800 nefazodone Drugs 0.000 description 3
- VRBKIVRKKCLPHA-UHFFFAOYSA-N nefazodone Chemical compound O=C1N(CCOC=2C=CC=CC=2)C(CC)=NN1CCCN(CC1)CCN1C1=CC=CC(Cl)=C1 VRBKIVRKKCLPHA-UHFFFAOYSA-N 0.000 description 3
- 229960002296 paroxetine Drugs 0.000 description 3
- 229960004688 venlafaxine Drugs 0.000 description 3
- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 description 3
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- -1 methyl olanzapine Chemical compound 0.000 description 2
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 description 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 description 1
- 208000020706 Autistic disease Diseases 0.000 description 1
- 208000020925 Bipolar disease Diseases 0.000 description 1
- 206010017543 Fungal skin infection Diseases 0.000 description 1
- 206010026749 Mania Diseases 0.000 description 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003001 depressive effect Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 208000035231 inattentive type attention deficit hyperactivity disease Diseases 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229960005017 olanzapine Drugs 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 208000028173 post-traumatic stress disease Diseases 0.000 description 1
- 229940001470 psychoactive drug Drugs 0.000 description 1
- 239000004089 psychotropic agent Substances 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 description 1
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 description 1
- 230000000697 serotonin reuptake Effects 0.000 description 1
- 201000009032 substance abuse Diseases 0.000 description 1
- 231100000736 substance abuse Toxicity 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000016686 tic disease Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10958498P | 1998-11-23 | 1998-11-23 | |
| US60/109,584 | 1998-11-23 | ||
| PCT/US1999/027647 WO2000030650A1 (en) | 1998-11-23 | 1999-11-22 | Desmethylolanzapine compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002530341A JP2002530341A (ja) | 2002-09-17 |
| JP2002530341A5 true JP2002530341A5 (enExample) | 2007-03-01 |
Family
ID=22328453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000583533A Withdrawn JP2002530341A (ja) | 1998-11-23 | 1999-11-22 | デスメチルオランザピン組成物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6348455B1 (enExample) |
| EP (1) | EP1133300B1 (enExample) |
| JP (1) | JP2002530341A (enExample) |
| AT (1) | ATE286398T1 (enExample) |
| AU (1) | AU757973B2 (enExample) |
| CA (1) | CA2351718A1 (enExample) |
| DE (1) | DE69923081T2 (enExample) |
| ES (1) | ES2237188T3 (enExample) |
| PT (1) | PT1133300E (enExample) |
| WO (1) | WO2000030650A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200402289A (en) * | 2002-05-17 | 2004-02-16 | Wyeth Corp | Methods of treating gastrointestinary and genitourinary pain disorders |
| PL199016B1 (pl) | 2002-06-20 | 2008-08-29 | Adamed Sp Z Oo | Sposób wytwarzania olanzapiny |
| US6831077B2 (en) * | 2002-07-25 | 2004-12-14 | Comprehensive Neuroscience, Inc. | Augmentation of atypical antipsychotic agent pharmacotherapy with chromium supplementation |
| MXPA05000294A (es) * | 2002-07-30 | 2005-08-19 | Peter Migaly | Terapia combinada para la depresion, prevencion de suicidios y varias condiciones medicas y psiquiatricas. |
| AR042806A1 (es) * | 2002-12-27 | 2005-07-06 | Otsuka Pharma Co Ltd | Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo |
| AU2003295235B2 (en) | 2002-12-27 | 2008-06-19 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and serotonin reuptake inhibitors for treatment of mood disorders |
| WO2004071417A2 (en) * | 2003-02-05 | 2004-08-26 | University Of Vermont And State Agricultural College | Inhibitors of candida albicans |
| PL198589B1 (pl) | 2004-11-22 | 2008-06-30 | Adamed Sp Z Oo | Sposób wytwarzania N-demetyloolanzapiny |
| US20060194769A1 (en) * | 2005-01-25 | 2006-08-31 | University Of Vermont And State Agricultural College | Small molecules that reduce fungal growth |
| US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
| EP2114150A4 (en) * | 2007-02-01 | 2010-03-10 | Alan I Green | COMBINATIONS OF BLOCKING OF DOPAMINERGIC D2 RECEPTORS WITH INHIBITION OF NOREPINEPHRINE RECAPTATION AND BLOCKING OF NOREPINEPHRINE ALPHA RECEPTORS |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4115568A (en) | 1974-11-26 | 1978-09-19 | Lilly Industries Limited | Thieno[3,2-b]-[1,5]benzodiazepines |
| US4590213A (en) * | 1983-04-08 | 1986-05-20 | Eli Lilly And Company | Anti-anxiety method |
| US5229382A (en) | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
| US5627178A (en) | 1991-04-23 | 1997-05-06 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
| US5605897A (en) | 1991-04-23 | 1997-02-25 | Eli Lilly And Company | 2-methyl-thieno-benzodiazepine |
| US5457101A (en) | 1994-06-03 | 1995-10-10 | Eli Lilly And Company | Thieno[1,5]benzoidiazepine use |
| US6274636B1 (en) | 1995-09-29 | 2001-08-14 | Eli Lilly And Company | Method for treating a tic disorder |
| AU1335397A (en) * | 1995-12-21 | 1997-07-17 | Eli Lilly And Company | Method for treating dermatitis |
| HUP9903684A3 (en) | 1995-12-22 | 2001-12-28 | Lilly Co Eli | Use of olanzapine for the preparation of pharmaceutical compositions treating depression |
| UA57727C2 (uk) | 1996-03-11 | 2003-07-15 | Елі Ліллі Енд Компані | Спосіб лікування надмірної агресивності |
| JP2000506859A (ja) * | 1996-03-11 | 2000-06-06 | イーライ・リリー・アンド・カンパニー | 双極性障害の処置方法 |
| NZ331845A (en) | 1996-03-11 | 2000-09-29 | Lilly Co Eli | Use of olanzapine for treating substance abuse, alcohol and nicotine dependency |
| EP0946179B1 (en) | 1996-03-11 | 2003-09-17 | Eli Lilly And Company | Use of olanzapine or a pharmaceutically acceptable salt for the manufacture of a medicament for the treatment of autism and mental retardation |
| GB9615767D0 (en) | 1996-07-26 | 1996-09-04 | Smithkline Beecham Plc | Novel treatment |
-
1999
- 1999-11-22 DE DE69923081T patent/DE69923081T2/de not_active Expired - Fee Related
- 1999-11-22 EP EP99960547A patent/EP1133300B1/en not_active Expired - Lifetime
- 1999-11-22 AT AT99960547T patent/ATE286398T1/de not_active IP Right Cessation
- 1999-11-22 AU AU17416/00A patent/AU757973B2/en not_active Ceased
- 1999-11-22 JP JP2000583533A patent/JP2002530341A/ja not_active Withdrawn
- 1999-11-22 CA CA002351718A patent/CA2351718A1/en not_active Abandoned
- 1999-11-22 US US09/444,590 patent/US6348455B1/en not_active Expired - Fee Related
- 1999-11-22 PT PT99960547T patent/PT1133300E/pt unknown
- 1999-11-22 ES ES99960547T patent/ES2237188T3/es not_active Expired - Lifetime
- 1999-11-22 WO PCT/US1999/027647 patent/WO2000030650A1/en not_active Ceased
-
2001
- 2001-12-19 US US10/026,303 patent/US6468997B2/en not_active Expired - Fee Related
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